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    • 87. 发明授权
    • Multi-criterial decision making system and method
    • 多标准决策制度和方法
    • US07155423B1
    • 2006-12-26
    • US09717332
    • 2000-11-20
    • John R. JosephsonBalakrishran ChandrasekaranMark CarrollNaresh Sundaram Iyer
    • John R. JosephsonBalakrishran ChandrasekaranMark CarrollNaresh Sundaram Iyer
    • G06F17/00G06N7/04
    • G06Q10/06Y10S707/99933
    • An architecture is disclosed for assistance with exploration of design and other decision spaces and for making decisions. These decision spaces may be very large. The architecture consists of three main components: A Seeker acquires candidates by generating or retrieving them, along with their scores according to one or more criteria. A Filter locates a relatively small number of promising candidates that are retained for further analysis. Various filters may be used to locate the promising candidates. A Viewer allows a user to examine trade-off diagrams, and other linked displays, that present the filtered candidates for evaluation, analysis, further exploration, and narrowing the choice set. The computational load of the Seeker may be distributed among a large number of clients in a client-server computing environment.
    • 披露了一种架构,用于协助探索设计和其他决策空间以及作出决策。 这些决策空间可能非常大。 该架构由三个主要组成部分组成:寻求者根据一个或多个标准通过生成或检索它们以及其分数来获取候选者。 过滤器定位了相对较少数量的有希望的候选人,用于进一步分析。 可以使用各种滤波器来定位有希望的候选者。 查看器允许用户检查权衡图和其他链接显示,呈现过滤的候选人进行评估,分析,进一步探索和缩小选择集。 Seeker的计算负载可以分布在客户端 - 服务器计算环境中的大量客户端之间。
    • 89. 发明申请
    • NANOPUMP DEVICES AND METHODS
    • US20060191831A1
    • 2006-08-31
    • US11279515
    • 2006-04-12
    • Derek HansfordRobbie WalczakAnthony Boiarski
    • Derek HansfordRobbie WalczakAnthony Boiarski
    • B01D63/00
    • F04B19/006B01D57/02B01D61/56B01L3/5027F04B17/00
    • Disclosed is a nanopump for pumping small volumes of electrolyte solution under the control of a voltage source. The device includes a chamber and a nanopore membrane which partitions the chamber into upstream and downstream regions. When a voltage potential is applied across the membrane, electroosmotic flow through the membrane channels produces a precise-volume flow between the two chamber regions. Also disclosed is a method for precis-volume pumping employing the nanopump. Also disclosed is device for determining the lengths of nucleic acid fragments in an electrolyte solution of different-length fragments is disclosed. The device includes a chamber having disposed therein, a nanopore channel extending between upstream and downstream chamber regions. By applying a voltage potential across upstream and downstream electrodes in the chamber regions, individual nucleic acid fragments contained in the solution are moved through the channel. A current detector detects time-dependent current flow across said membrane, and from the measured flow times, fragments lengths can be estimated. Also disclosed is a device for separating macromolecules in a solution of macromolecules having different molecular sizes. The device includes a separation chamber having upstream and downstream ends, and one or more nanopore membranes disposed in the chamber between said upstream and downstream ends, partitioning the chamber into two or more chamber regions, respectively. Upstream and downstream electrodes are disposed at the upstream and downstream ends of the chamber, respectively. A controller in the device has a power source operatively connected to the electrodes for applying a selected voltage potential across said channel, to pump solution through each of said membranes, in an upstream-to-downstream direction, wherein macromolecules contained in the solution are filtered at each successive membrane, to concentrate successively smaller macromolecules in successively more downstream chamber regions.