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    • 81. 发明授权
    • Self-locking knob for adjustable control mechanism
    • 自锁旋钮可调控制机构
    • US4955253A
    • 1990-09-11
    • US902045
    • 1986-08-26
    • Yoshio SakaiTakeshi Yamada
    • Yoshio SakaiTakeshi Yamada
    • H05B3/00G05G1/00G05G1/10G05G5/12G05G5/18
    • G05G1/10G05G5/18Y10S16/30Y10T16/506Y10T74/2066Y10T74/2084
    • A control mechanism having a dial and cooperating structure for selectively locking the dial in any one of a plurality of angularly related positions. The locking mechanism is configured to provide a force or manipulating characteristic precluding operation thereof by accident or by young children, such as infants, thereby effectively precluding undesired resetting of the associated control mechanism. The locking structure is formed integrally with the respective relatively movable parts of the mechanism, including the structure for providing the biasing of the locking mechanism to the locking disposition. The locking mechanism is resiliently biased and includes a graspable portion which when grasped to effect movement of the control overcomes the resilient biasing. The biasing structure automatically relocks the dial upon release of the graspable portion.
    • 一种具有拨盘和配合结构的控制机构,用于选择性地将表盘锁定在多个角度相关位置中的任一个中。 锁定机构被配置成提供强制或操纵特性,排除其意外或幼儿(例如婴儿)的操作,从而有效地排除相关联的控制机构的不期望的重置。 锁定结构与机构的各个可相对移动的部分一体地形成,包括用于提供锁定机构偏压到锁定配置的结构。 锁定机构被弹性地偏置并且包括可握持部分,当被抓握以实现控制的移动时克服了弹性偏压。 偏置结构在释放可抓握部分时自动重新拨盘。
    • 85. 发明授权
    • Detection of digestive organ cancer, gastric cancer, colorectal cancer, pancreatic cancer, and biliary tract cancer by gene expression profiling
    • 通过基因表达谱检测消化器官癌,胃癌,结肠直肠癌,胰腺癌和胆道癌
    • US08932990B2
    • 2015-01-13
    • US13391858
    • 2010-08-03
    • Shuichi KanekoMasao HondaYoshio SakaiTaro Yamashita
    • Shuichi KanekoMasao HondaYoshio SakaiTaro Yamashita
    • C40B30/04C12Q1/68C40B40/06
    • C12Q1/6886C12Q2600/158C12Q2600/16
    • The present invention provides a method and a reagent for detecting a digestive organ cancer, gastric cancer, colorectal cancer, pancreatic cancer, or biliary tract cancer patient by analyzing genes with expression levels (in peripheral blood) that vary in association with digestive organ cancer, gastric cancer, colorectal cancer, pancreatic cancer, or biliary tract cancer cases, compared with normal healthy subjects. Specifically, the method for detecting a digestive organ cancer, gastric cancer, colorectal cancer, pancreatic cancer, or biliary tract cancer patient based on expression profiles comprises obtaining the expression profile of at least one gene selected from the group consisting of probes corresponding to genes with expression levels (in peripheral blood) that vary in digestive organ cancer, gastric cancer, colorectal cancer, pancreatic cancer, and biliary tract cancer cases, compared with normal healthy subjects. The reagent for detecting digestive organ cancer, gastric cancer, colorectal cancer, pancreatic cancer, or biliary tract cancer contains nucleotides or partial sequences thereof consisting of the nucleotide sequence of at least one gene selected from the group consisting of probes with expression levels that vary in digestive organ cancer, gastric cancer, colorectal cancer, pancreatic cancer, or biliary tract cancer, or nucleotides containing sequences complementary thereto.
    • 本发明提供了通过分析与消化器官癌相关的变化的表达水平(外周血)的基因来检测消化器官癌,胃癌,结肠直肠癌,胰腺癌或胆道癌患者的方法和试剂, 胃癌,结肠直肠癌,胰腺癌或胆道癌,与正常健康人相比。 具体地,基于表达谱,检测消化器官癌,胃癌,结肠直肠癌,胰腺癌或胆道癌患者的方法包括获得至少一种基因的表达谱,所述基因选自对应于具有 与正常健康受试者相比,消化器官癌,胃癌,结肠直肠癌,胰腺癌和胆道癌患者的表达水平(外周血)差异不大。 用于检测消化器官癌,胃癌,结肠直肠癌,胰腺癌或胆道癌的试剂含有由至少一种基因的核苷酸序列组成的核苷酸或其部分序列,所述核苷酸序列选自下组的探针:表达水平在 消化器官癌,胃癌,结肠直肠癌,胰腺癌或胆道癌,或含有与其互补的序列的核苷酸。
    • 90. 发明授权
    • Digital scale
    • 数字刻度
    • US07596453B2
    • 2009-09-29
    • US11878840
    • 2007-07-27
    • Yoshio Sakai
    • Yoshio Sakai
    • G06F19/00G06F15/00
    • G01G19/44G01G23/10
    • A digital scale is provided that switches a measuring interval according to the amount of variation of sampled data, and computes a weight. Embodiments include a scale with pre-stored scale intervals set at multiple levels, and allowable ranges of fluctuation that correspond to the scale intervals. The scale acquires digital data of a load continuously, and computes a predetermined number, or a fluctuation range in a predetermined time, of the acquired digital data. The scale then determines the degree of variation of the digital data by comparing the computed fluctuation range with the allowable range of fluctuation stored for each scale interval, and switches the scale interval based on the determined degree of variation, thereby allowing the scale to measure and compute the weight of the load even if the fluctuation is large.
    • 提供数字刻度,根据采样数据的变化量切换测量间隔,并计算重量。 实施例包括具有设置在多个级别上的预先存储的刻度间隔的刻度,以及对应于刻度间隔的允许的波动范围。 该刻度尺持续地获取负载的数字数据,并计算所获取的数字数据的预定数量或预定时间的波动范围。 然后,通过将计算出的波动范围与每个刻度间隔所存储的波动允许范围进行比较来确定数字数据的变化程度,并根据确定的变化程度切换刻度间隔,从而允许刻度测量和 即使波动较大,也可以计算负载的重量。