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    • 81. 发明授权
    • Quinazoline derivatives and quinazoline complex protein kinase inhibitor for inhibiting multiplication of tumor cells and preparation method thereof
    • 喹唑啉衍生物和喹唑啉复合蛋白激酶抑制剂抑制肿瘤细胞增殖及其制备方法
    • US09233995B2
    • 2016-01-12
    • US13882100
    • 2011-10-27
    • Fuyi WangQun LuoLiyun JiWei ZhengShuang LvXianchan Li
    • Fuyi WangQun LuoLiyun JiWei ZhengShuang LvXianchan Li
    • C07F15/00C07D239/94C07D403/12C07F17/02
    • C07F15/0053C07D239/94C07D403/12C07F15/0046C07F17/02
    • Quinazoline derivatives represented by general formula (1) and quinazoline complexes as protein kinase inhibitors, and their preparation methods are provided. Wherein, in general formula (1), at least one of R and R′ is a group containing an atom capable of coordinating with noble metals, m and n are either the same or different and are integers from 0 to 5. Said quinazoline complex as protein kinase inhibitor is formed by coordination compound containing noble metal and said quinazoline derivative ligand capable of coordinating with noble metal in the coordination compound. Used as tyrosine protein kinase inhibitors, Quinazoline derivatives and quinazoline complexes as protein kinase inhibitors provided by the present invention have exhibited good inhibitory effect on proliferation of various tumor cells including human breast cancer cells line (drug-resistant) MCF-7/A, human breast cancer cell line (sensitive) MCF-7/S, prostate cancer cell PC-3, keratinocytes Colo-16, human non-small cell lung cancer cell line A549, etc.
    • 提供了由通式(1)表示的喹唑啉衍生物和喹唑啉配合物作为蛋白激酶抑制剂及其制备方法。 其中,在通式(1)中,R和R'中的至少一个是含有与贵金属配位的原子的基团,m和n可以相同或不同,为0〜5的整数。所述喹唑啉络合物 因为蛋白激酶抑制剂是由含有贵金属的配位化合物和能与配位化合物中的贵金属配位的喹唑啉衍生物配体形成的。 作为酪氨酸蛋白激酶抑制剂,本发明提供的蛋白激酶抑制剂喹唑啉衍生物和喹唑啉配合物对包括人乳腺癌细胞系(耐药性)MCF-7 / A,人类在内的各种肿瘤细胞的增殖具有良好的抑制作用 乳腺癌细胞株(敏感)MCF-7 / S,前列腺癌细胞PC-3,角质形成细胞Colo-16,人非小细胞肺癌细胞株A549等
    • 85. 发明授权
    • Method and apparatus of ordering search results
    • 排序搜索结果的方法和装置
    • US08538975B2
    • 2013-09-17
    • US13381069
    • 2011-09-26
    • Huaxing JinWei ZhengPeng HuangXu YangFeng LinJiong FengQin Zhang
    • Huaxing JinWei ZhengPeng HuangXu YangFeng LinJiong FengQin Zhang
    • G06F7/00
    • G06F17/3053G06F17/30964
    • Ordering search results may include obtaining an exposed log file from a log system, computing a Bayesian posterior probability for relevancy between the log file and a search request, computing an expected value of the relevancy between the log file and the search request based on the Bayesian posterior probability, storing the search request and an identifier of the log file as a key and the expected value of the relevancy between the log file and the search request as a value into a search data structure, in response to receiving a search request submitted by a user, finding expected values of relevancy between the submitted search request and log files that are relevant to the submitted search request from the search data structure, and ordering the found log files in a descending order of the expected values.
    • 订购搜索结果可以包括从日志系统获取暴露的日志文件,计算日志文件和搜索请求之间的相关性的贝叶斯后验概率,基于贝叶斯计算日志文件和搜索请求之间的相关性的期望值 后验概率,响应于接收到由所述搜索请求提交的搜索请求,将所述搜索请求和所述日志文件的标识符作为密钥存储,并将所述日志文件和所述搜索请求之间的相关性的期望值作为值存储到搜索数据结构中 一个用户,从搜索数据结构中找到所提交的搜索请求和与提交的搜索请求相关的日志文件之间的相关性的预期值,并按照预期值的降序对找到的日志文件进行排序。
    • 86. 发明授权
    • Method, device and system for realizing kernel online patching
    • 实现内核在线修补的方法,设备和系统
    • US08499289B2
    • 2013-07-30
    • US12703409
    • 2010-02-10
    • Huafei DaiWei Zheng
    • Huafei DaiWei Zheng
    • G06F9/45
    • G06F8/656
    • A method, a device, and a system for realizing kernel online patching are provided. The method includes loading a pre-generated patch file in an operating system, setting a first breakpoint at an execution start position of the primitive function when a system thread executes the primitive function and a breakpoint exception occurs during the thread execution process due to the first breakpoint, modifying a returning execution address of the first breakpoint into the destination address of the patch function corresponding to the primitive function according to the first corresponding relation, and removing the first breakpoint. The kernel online patching implementation has a small impact on the normal operation of the operating system. The patch function becomes valid without restarting the operating system, thereby satisfying the high reliability requirements of carrier-class products.
    • 提供了一种实现内核在线修补的方法,设备和系统。 该方法包括在操作系统中加载预生成的补丁文件,当系统线程执行原始函数时,在原始函数的执行开始位置设置第一个断点,并且在线程执行过程期间发生断点异常,这是由于第一个 断点,根据第一对应关系将第一断点的返回执行地址修改为对应于原语函数的补丁函数的目的地地址,以及去除第一断点。 内核在线修补实现对操作系统的正常运行影响很小。 补丁功能无效,无需重新启动操作系统,从而满足电信级产品的高可靠性要求。
    • 87. 发明申请
    • Accelerating Service Processing Using Fast Path TCP
    • 使用快速路径TCP加速服务处理
    • US20130136139A1
    • 2013-05-30
    • US13567115
    • 2012-08-06
    • Wei ZhengLiang Han
    • Wei ZhengLiang Han
    • H04L12/56
    • H04L67/1014H04L69/161
    • A service gateway includes a fast path module for processing data packets without using packet buffers and a normal path module for processing data packets using packet buffers. The fast path module receives a service request data packet from a client side session, determines that the service request data packet cannot be processed by the fast path module, and in response, sends the service request data packet to the normal path module. After receiving the service request data packet, the normal path module retrieves a first proxy session record created by the fast path module, where the first proxy session record is associated with a client session record for the client side session, creates a second proxy session record based on the service request data packet and the client session record, and processes the service request data packet according to the second proxy session record.
    • 服务网关包括用于处理数据分组而不使用分组缓冲器的快速路径模块和用于使用分组缓冲器来处理数据分组的正常路径模块。 快速路径模块从客户端会话接收服务请求数据包,确定服务请求数据包不能被快速路径模块处理,响应时间将服务请求数据包发送到正常路径模块。 在接收到服务请求数据分组之后,正常路径模块检索由快速路径模块创建的第一代理会话记录,其中第一代理会话记录与客户端会话的客户端会话记录相关联,创建第二代理会话记录 基于所述服务请求数据分组和所述客户端会话记录,并根据所述第二代理会话记录处理所述服务请求数据分组。
    • 88. 发明申请
    • METHOD, DEVICE AND SYSTEM FOR ACTIVATING ON-LINE PATCH
    • 方法,设备和系统用于激活在线控制
    • US20120102476A1
    • 2012-04-26
    • US13336227
    • 2011-12-23
    • Jiaqiang YUWei Zheng
    • Jiaqiang YUWei Zheng
    • G06F9/44G06F9/45
    • G06F8/67G06F8/656
    • Embodiments of the present invention provide a method, a device and a system for activating an on-line patch. The method comprises: positioning an address of a patch function and an entry address of a to-be-patched function; writing, in a middle segment, a long-jump instruction for jumping to the patch function based on the address of the patch function and the entry address of the to-be-patched function, where the middle segment is a storage space, which is located before or after the entry position of the to-be-patched function and can at least store one long-jump instruction; and modifying an instruction at the entry position of the to-be-patched function to a short-jump instruction for jumping to the middle segment, so as to jump to the middle segment after the short jump instruction is executed, and then to jump to and execute the patch function through that instructions in the middle segment are executed.
    • 本发明的实施例提供一种用于激活在线补丁的方法,装置和系统。 该方法包括:定位补丁功能的地址和待修补功能的入口地址; 在中间段中,根据补丁功能的地址和待修补功能的入口地址写入跳转到补丁功能的长跳转指令,其中中间段是存储空间,其中 位于待修补功能的入口位置之前或之后,并且可以至少存储一个长跳转指令; 并且将待修补功能的入口位置处的指令修改为跳转到中间段的短跳转指令,以便在执行短跳转指令之后跳转到中间段,然后跳转到 并通过中间段的指令执行补丁功能。
    • 89. 发明授权
    • OP-AMP sharing with input and output reset
    • OP-AMP共享输入和输出复位
    • US08120423B2
    • 2012-02-21
    • US12960858
    • 2010-12-06
    • Liping DengTiejun DaiWei ZhengXueqing Wang
    • Liping DengTiejun DaiWei ZhengXueqing Wang
    • H03F1/02
    • H03F3/45H03F3/005
    • An operational amplifier with two pairs of differential inputs for use with an input switch capacitor network. The operational amplifier has reset devices for resetting the second pair of differential inputs while amplifying the first pair of differential inputs, and for resetting the first pair of differential inputs while amplifying the second pair of differential inputs for reducing memory effect in electronic circuits. In an embodiment, the amplifier has an additional reset device for resetting the outputs during a prophase of amplifying the first pair of differential inputs and a prophase of amplifying the second pair of differential inputs.
    • 具有两对差分输入的运算放大器,用于与输入开关电容网络一起使用。 运算放大器具有复位装置,用于复位第二对差分输入,同时放大第一对差分输入,并用于复位第一对差分输入,同时放大第二对差分输入,以减少电子电路中的记忆效应。 在一个实施例中,放大器具有用于在放大第一对差分输入的前期期间复位输出的附加复位装置以及放大第二对差分输入的前期。