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81. 发明申请

US20200208612A1 Bionic Root Foundation for Onshore Wind Turbine Generators 审中-公开
公开(公告)号：US20200208612A1
公开(公告)日：2020-07-02
申请号：US16278010
申请日：2019-02-15
申请人： Dongyuan Wang , Jing Li , Ying Han
发明人： Dongyuan Wang , Jing Li , Ying Han
IPC分类号： F03D13/20 , E02D27/42
摘要： Embodiments of the present foundation for wind turbine generators comprise four structural members: one short central hollow pier, one continued grade beam, several solid piles built below the continued grade beam, and several arm grade beams linking the structural members. All structural members are constructed of cast-in-place concrete reinforced with rebars, and all connections are fixed and rigid. The short central hollow pier positions in the center of the system, functions as a hub to take the loadings and continuously to transfer and distribute the loadings further to the continued grade beam, arranged circumferentially in outer periphery of the system, and deeper to the solid piles, through the arm grade beams, which have a varied section and embed into ground in the far end. The present foundation utilizes the ground to shape and form the structural members, no formworks, backfilling and compaction is needed.

82. 发明授权

US10175378B2 System and method of focusing an array laterolog 有权
公开(公告)号：US10175378B2
公开(公告)日：2019-01-08
申请号：US14403455
申请日：2012-07-13
申请人： Shanjun Li , Luis Emilio San Martin , Michael S. Bittar , Jing Li
发明人： Shanjun Li , Luis Emilio San Martin , Michael S. Bittar , Jing Li
IPC分类号： G01V3/20 , G01V3/24
摘要： Various embodiments include apparatus and methods to make resistivity measurements in a borehole using tool having an array of electrodes operable to provide focused currents, measure corresponding voltages, and measure corresponding voltage differences to determine resistivity. Tools can be configured to operate at a plurality of modes when voltage differences at some frequencies are effectively unreadable. Additional apparatus, systems, and methods are disclosed.

83. 发明授权

US09810805B2 Method and apparatus to detect a conductive body 有权
公开(公告)号：US09810805B2
公开(公告)日：2017-11-07
申请号：US13818380
申请日：2011-08-03
申请人： Michael S. Bittar , Jing Li
发明人： Michael S. Bittar , Jing Li
IPC分类号： G01V3/28 , G01V3/26 , E21B47/022 , G06F17/00
CPC分类号： G01V3/26 , E21B47/02216 , G06F17/00
摘要： Various embodiments include apparatus and methods to detect and locate conductive bodies and/or provide steam-assisted gravity drainage (SAGD) steering operation. Tools can be configured with receiving sensors (310) arranged to cancel substantially a primary signal associated with a probe signal without rotating the receiving sensors to cancel the primary signal and to capture a secondary signal generated from a conductive body (301) below the earth's surface. Additional apparatus, systems, and methods are disclosed.

84. 发明授权

US09547100B2 Multi-array laterolog tools and methods with differential voltage measurements 有权
标题翻译：具有差分电压测量的多阵列后验工具和方法
公开(公告)号：US09547100B2
公开(公告)日：2017-01-17
申请号：US13884034
申请日：2011-11-02
申请人： Shanjun Li , Luis E San Martin , Michael S Bittar , Jing Li
发明人： Shanjun Li , Luis E San Martin , Michael S Bittar , Jing Li
IPC分类号： G01V3/20 , G01V3/24 , E21B49/00 , E21B47/10 , G01V3/28
CPC分类号： G01V3/20 , E21B47/102 , E21B49/00 , G01V3/24 , G01V3/28 , G01V2200/16
摘要： Multi-array laterolog tool systems and methods acquire a set of array measurements sufficient to provide laterolog tool measurements of differing array sizes. Such systems and method offer multiple depths of investigation while offering greater measurement stability in borehole environments having high resistivity contrasts. In at least some system embodiments, a wireline or LWD tool body has a center electrode positioned between multiple pairs of guard electrodes and a pair of return electrodes. The tool's electronics provide a current from the center electrode to the pair of return electrodes and currents from each pair of guard electrodes to the pair of return electrodes. Each of the currents may be distinguishable by frequency or distinguishable by some other means. This novel arrangement of currents provides a complete set of measurements that enables one tool to simultaneously emulate a whole range of laterolog tools.
摘要翻译：多阵列后验工具系统和方法获取足够的阵列测量集，以提供不同阵列大小的后者工具测量。这种系统和方法提供多个调查深度，同时在具有高电阻率对比度的钻孔环境中提供更大的测量稳定性。在至少一些系统实施例中，有线或LWD工具主体具有位于多对保护电极和一对返回电极之间的中心电极。工具的电子器件提供从中心电极到一对返回电极的电流以及从每对保护电极到一对返回电极的电流。每个电流可以通过频率区分或通过某种其他方式可区分。这种新颖的电流布置提供了一整套测量，使一个工具能够同时模拟一整套后期工具。

85. 发明授权

US09523074B2 Sub-totipotent stem cell product and apparent hereditary modifying label thereof 有权
标题翻译：亚全能干细胞产品及其显性遗传修饰标签
公开(公告)号：US09523074B2
公开(公告)日：2016-12-20
申请号：US13992619
申请日：2011-12-02
申请人： Chunhua Zhao , Jing Li , Hongling Li , Jianhe Chen , Qin Han , Kanghua Li , Jing Wang
发明人： Chunhua Zhao , Jing Li , Hongling Li , Jianhe Chen , Qin Han , Kanghua Li , Jing Wang
IPC分类号： C12N5/074 , C12Q1/68 , C12N5/077 , C12N5/0775 , G01N33/68 , G01N33/569
CPC分类号： C12N5/0607 , C12Q1/6881 , G01N33/56966 , G01N33/6875
摘要： Provided are a sub-totipotent stem cell product and epigenetic modification label thereof, a method for inducing the generation of the sub-totipotent stem cell product and identification for the epigenetic modification label of the differentiation potential of stem cells. Also provided is a use of histone modification states of sub-totipotent genes and/or differentiation related genes to predict the epigenetic modification label of the differentiation potentials of stem cells.
摘要翻译：提供了全能的干细胞产物和表观遗传修饰标记，诱导产生亚全能干细胞产物的方法和干细胞分化潜能的表观遗传修饰标记物的鉴定。还提供了使用亚全能基因和/或分化相关基因的组蛋白修饰状态来预测干细胞分化潜能的表观遗传修饰标记。

86. 发明授权

US09489289B2 Adaptive framework automatically prioritizing software test cases 有权
标题翻译：自适应框架自动优先考虑软件测试用例
公开(公告)号：US09489289B2
公开(公告)日：2016-11-08
申请号：US14565220
申请日：2014-12-09
申请人： Ziheng Hu , Jing Li , Xin Li , Chen Zhou , Longhui Chang
发明人： Ziheng Hu , Jing Li , Xin Li , Chen Zhou , Longhui Chang
IPC分类号： G06F11/00 , G06F11/36
CPC分类号： G06F11/3684 , G06F11/3688
摘要： An automated, self-adaptive framework prioritizes software testing in a consistent and effective manner. A metric evaluates past test execution information for assigning regression testing priority. The metric may be calculated with reference to one or more of the following factors taken in combination: requirement, coverage, history, and cost. The requirement factor considers customer-assigned priority of testing the code, complexity of implementing the code, and proneness of the code to faults. The coverage factor considers code coverage, feature coverage, and common usage rate. The history factor considers previous bug found rate, case stable rate, and priority to calculate. The cost factor considers test case execution time, and step length. A value of each factor for one test case is measured according to that test case and is not related to other test cases. The calculation result representing the metric for each test case determines a priority of the test case.
摘要翻译：自动化的自适应框架以一致和有效的方式优先考虑软件测试。指标评估过去的测试执行信息，以分配回归测试优先级。可以参考以下组合中的一个或多个因素来计算度量：要求，覆盖率，历史和成本。要求因素考虑了客户分配的测试代码的优先级，实现代码的复杂性和代码的错误。覆盖率考虑代码覆盖率，功能覆盖率和常用使用率。历史因素考虑以前的错误发现率，病例稳定率和优先级来计算。成本因素考虑测试用例执行时间和步长。一个测试用例的每个因子的值根据该测试用例进行测量，与其他测试用例无关。表示每个测试用例的度量的计算结果决定了测试用例的优先级。

87. 发明申请

US20160244417A1 CATHEPSIN CYSTEINE PROTEASE INHIBITORS 有权
公开(公告)号：US20160244417A1
公开(公告)日：2016-08-25
申请号：US15027271
申请日：2014-10-03
申请人： Shawn STACHEL , Jing LI , Anthony GINNETTI
发明人： Shawn Stachel , Daniel V. Paone , Jing Li , Anthony Ginnetti , John Lim , Jianmin Fu , Shimin Xu
IPC分类号： C07D277/30 , A61K31/541 , C07D417/04 , A61K31/5377 , C07D277/52 , C07D417/10 , A61K31/427 , C07D277/34 , C07D417/14 , A61K31/4439 , A61K45/06 , C07D263/32
CPC分类号： C07D277/30 , A61K31/415 , A61K31/427 , A61K31/44 , A61K31/4439 , A61K31/5377 , A61K31/541 , A61K45/06 , C07D231/12 , C07D263/22 , C07D263/32 , C07D277/22 , C07D277/34 , C07D277/52 , C07D405/04 , C07D417/04 , C07D417/10 , C07D417/14 , Y02A50/423 , A61K2300/00
摘要： This invention relates to a novel class of compounds which are cysteine protease inhibitors, including but not limited to, inhibitors of cathepsins K, L, S and B. These compounds are useful for treating diseases in which inhibition of bone resorption is indicated, such as osteoporosis.

88. 发明授权

US09341734B2 Apparatus and method for bed boundary detection 有权
标题翻译：床边界检测装置及方法
公开(公告)号：US09341734B2
公开(公告)日：2016-05-17
申请号：US13786302
申请日：2013-03-05
申请人： Ce Liu , Jing Li
发明人： Ce Liu , Jing Li
IPC分类号： G06F11/00 , G01V3/30 , E21B47/022
CPC分类号： G01V3/30 , E21B47/02216
摘要： A method for performing detection of a bed boundary can include deploying a tool body with a longitudinal axis in a borehole, modulating the magnetic moments of electromagnetic signals to be transmitted by the first transmitter and the second transmitter, firing the first transmitter and the second transmitter substantially simultaneously, utilizing the receiver to receive and measure the modulated electromagnetic signals from the first transmitter and the second transmitter, and computing the orientation and location of the bed boundary based on the amplitudes and phases of the electromagnetic signals received and measured at the receiver. The tool body can be deployed with a first transmitter, a second transmitter, and a receiver, all of which are oriented in different directions. The vector of the total magnetic moment of the modulated electromagnetic signals can electrically rotate during firing. A corresponding apparatus for detection of a bed boundary is also provided.
摘要翻译：用于执行床边界检测的方法可以包括在钻孔中布置具有纵向轴线的工具主体，调制由第一发射器和第二发射器传输的电磁信号的磁矩，点火第一发射器和第二发射器基本上同时利用接收机接收并测量来自第一发射机和第二发射机的调制电磁信号，并且基于在接收机处接收和测量的电磁信号的幅度和相位来计算床边界的取向和位置。工具主体可以部署有第一发射器，第二发射器和接收器，所有这些都沿不同的方向定向。调制电磁信号的总磁矩矢量可以在点火过程中电旋转。还提供了用于检测床边界的相应装置。

89. 发明授权

US09322796B2 Fluid resistivity sensor 有权
标题翻译：流体电阻率传感器
公开(公告)号：US09322796B2
公开(公告)日：2016-04-26
申请号：US13695368
申请日：2010-06-01
申请人： Jing Li , Michael S. Bittar
发明人： Jing Li , Michael S. Bittar
IPC分类号： G01N27/06 , G01N27/07 , G01V3/24 , G01N27/04 , G01N27/02
CPC分类号： G01N27/06 , G01N27/02 , G01N27/04 , G01N27/07 , G01V3/24
摘要： Various embodiments include apparatus and methods of determining resistivity of fluids downhole in a well. The apparatus and methods may include using a sensor that employs a focused electric dipole as a transmitter and a uses a receiver to detect the electric current strength in the fluid under measurement responsive to the transmitter. Additional apparatus, systems, and methods are disclosed.
摘要翻译：各种实施例包括确定井中井下的流体的电阻率的装置和方法。该装置和方法可以包括使用采用聚焦电偶极子作为发射器的传感器，并且使用接收器来响应于发射器来检测被测流体中的电流强度。公开了附加装置，系统和方法。

90. 发明授权

US09249231B2 Motif-specific and context-independent antibodies that specifically bind to a cleaved caspase motif 有权
标题翻译：与特异性结合切割的半胱天冬酶基序的母体特异性和上下文相关抗体
公开(公告)号：US09249231B2
公开(公告)日：2016-02-02
申请号：US13289651
申请日：2011-11-04
申请人： Michael Comb , Ailan Guo , John Edward Rush, II , Jun-Ming Cai , Jing Li , Jing Zhou
发明人： Michael Comb , Ailan Guo , John Edward Rush, II , Jun-Ming Cai , Jing Li , Jing Zhou
IPC分类号： C07K16/44 , C07K16/00 , C12N5/07
CPC分类号： C07K16/18 , C07K16/44 , C07K2317/14 , C07K2317/20 , C07K2317/33 , C07K2317/34
摘要： There is provided a motif-specific, context-independent antibody that specifically binds a recurring, modified motif consisting of (i) at least one sumoylated lysine residue, and (ii) one or more degenerate amino acids bound by a peptide bond to said sumoylated lysine residue, said antibody specifically binding said motif in a plurality of non-homologous peptides or proteins within an organism in which it recurs. Also provided is a motif-specific, context-independent antibody that specifically binds a recurring, modified motif consisting of (i) a C-terminal aspartic acid residue, and (ii) one or more degenerate amino acids bound by a peptide bond to said C-terminal aspartic acid residue, said antibody specifically binding said motif in a plurality of non-homologous peptides or proteins within an organism in which it recurs.
摘要翻译：提供了一种特异性基因，独立于上下文的抗体，其特异性结合由（i）至少一个sumoylated赖氨酸残基组成的复发性修饰基序，和（ii）通过肽键与所述sumoylated结合的一个或多个简并氨基酸赖氨酸残基，所述抗体特异性结合所述基序在其再次发生的生物体内的多个非同源肽或蛋白质中。还提供了一种特异性基因，独立于上下文的抗体，其特异性结合由（i）C末端天冬氨酸残基组成的重复修饰基序，和（ii）一个或多个与肽键结合的简并氨基酸与所述 C末端天冬氨酸残基，所述抗体特异性结合所述基序在其再次发生的生物体内的多个非同源肽或蛋白质中。

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