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81. 发明授权

US06559692B2 Output driver for a 10baset/100basetx ethernet physical layer line interface 有权
标题翻译： 10baset / 100basetx以太网物理层线路接口的输出驱动程序
公开(公告)号：US06559692B2
公开(公告)日：2003-05-06
申请号：US09299051
申请日：1999-04-23
申请人： Eric Kimball , Perry Heedley , Baker Scott , Eric Smith , Stephen Hodapp , Sumant Ranganathan , Mohammad Navabi
发明人： Eric Kimball , Perry Heedley , Baker Scott , Eric Smith , Stephen Hodapp , Sumant Ranganathan , Mohammad Navabi
IPC分类号： H03B100
CPC分类号： H04L7/0331 , H04L25/0266 , H04L25/0274 , H04L25/0278 , H04L25/028 , H04L25/0292 , H04L25/4904
摘要： A multi-path unity gain buffer circuit and method are implemented in a slew amplifier. The multi-path unity buffer has a high frequency signal path and a low frequency signal path. The high frequency signal path has a differential amplifier powered for providing a high frequency, low accuracy buffering operation. The low frequency signal path is coupled to the high frequency signal path. The low frequency signal path has an operational amplifier powered to provide a low frequency, high bandwidth buffering operation. An output of the operational amplifier is fed back to an input of the operational amplifier through a current varying element that varies current levels of the input of the operational amplifier to remove a level shift of an output signal of the differential amplifier.
摘要翻译：多路单位增益缓冲电路和方法在压摆放大器中实现。多径单位缓冲器具有高频信号路径和低频信号路径。高频信号路径具有用于提供高频，低精度缓冲操作的差分放大器。低频信号路径耦合到高频信号路径。低频信号路径具有用于提供低频，高带宽缓冲操作的运算放大器。运算放大器的输出通过电流变化元件反馈到运算放大器的输入，该电流变化元件改变运算放大器的输入的电流电平以去除差分放大器的输出信号的电平移位。

82. 外观设计

USD467294S1 Hexagonal insecticide coil 失效
标题翻译：六角虫杀虫线圈
公开(公告)号：USD467294S1
公开(公告)日：2002-12-17
申请号：US29133923
申请日：2000-12-11
申请人： Bruce Graham Kemmis , Rosita Junus , Eric Smith , Margaret Lee Bosworth
设计人： Bruce Graham Kemmis , Rosita Junus , Eric Smith , Margaret Lee Bosworth

83. 发明授权

US06468238B1 Halo crown 有权
标题翻译：光晕冠
公开(公告)号：US06468238B1
公开(公告)日：2002-10-22
申请号：US09687135
申请日：2000-10-13
申请人： J. Riley Hawkins , John Knapik , Eric Smith
发明人： J. Riley Hawkins , John Knapik , Eric Smith
IPC分类号： A61F500
CPC分类号： A61F5/055 , A61B90/14
摘要： A halo crown has depending posterior legs adjustable in multiple dimensions for conveniently adjusting the halo crown to a patient's skull. Each leg slides along a single axis yet provides adjustments in three dimensions due to a portion thereof extending downwardly, inwardly and rearwardly and the orientation of the axis.
摘要翻译：晕冠具有多个尺寸可调整的后腿，以方便地将晕冠调整到患者的头骨。每个腿沿着单个轴线滑动，但是由于其一部分向下，向内和向后延伸并且轴线的取向而在三个维度上提供调节。

84. 发明授权

US5701974A Railway hand brake apparatus with visual condition indicator 失效
标题翻译：具有视觉状态指示器的铁路手制动装置
公开(公告)号：US5701974A
公开(公告)日：1997-12-30
申请号：US486108
申请日：1995-08-16
申请人： Wajih Kanjo , Eric Smith , Thomas J. Demoise , Michael Girotti , Thomas McCabe , Charles B. Fessler , Scott Natschke
发明人： Wajih Kanjo , Eric Smith , Thomas J. Demoise , Michael Girotti , Thomas McCabe , Charles B. Fessler , Scott Natschke
IPC分类号： B60T7/18 , B60T13/40 , B60T17/22 , B61H13/02 , F16D66/00
CPC分类号： B60T7/18 , B60T13/406 , B60T17/228 , B61H13/02
摘要： Apparatus for indicating the condition of hand brakes on railway cars and for applying and releasing railway car parking or hand brakes automatically in response to predetermined conditions including movement of a train, wayside conditioning apparatus, wayside operating mechanism, a signal controlled by an operator and performance of predetermined railway operating procedures, such as completion of an air brake test procedure. The apparatus may respond to mechanical, electrical and electronic signals and may operate on pneumatic or electric power provided from the service air brake system of a train or from a source of power outside of such air brake system.
摘要翻译：用于指示铁路车辆上的手制动器的状况的装置，以及响应于包括列车的移动，路边调节装置，路旁操作机构，由操作者控制的信号和性能的预定条件自动地施加和释放铁路停车场或手刹预定的铁路操作程序，如完成空气制动测试程序。该装置可以响应机械，电气和电子信号，并且可以对从列车的服务空气制动系统或从这种空气制动系统外部的动力源提供的气动或电力进行操作。

85. 发明授权

US11503817B1 Fish lures and methods for making fish lures and luring fish 有权
公开(公告)号：US11503817B1
公开(公告)日：2022-11-22
申请号：US16575373
申请日：2019-09-18
申请人： Eric Smith
发明人： Eric Smith
IPC分类号： A01K85/18
摘要： Soft bait lures emulating a fish are provided. The lure can provide at least one channel within at least one of the exterior surfaces of the tail. Methods for manufacturing a soft bait fishing lure are also provided. The methods can include removing one or more portions of one or more exterior surfaces of the tail to define one or more channels within the one or more surfaces of the tail. Methods for luring fish using a soft bait fishing lure are also provided. The methods can include channeling at least some of the water through one or more channels within the surface of the tail of the fishing lure.

86. 发明申请

US20180282411A1 Heavy Chain Constant Regions with Reduced Binding to Fc Gamma Receptors 审中-公开
公开(公告)号：US20180282411A1
公开(公告)日：2018-10-04
申请号：US15562881
申请日：2016-03-30
申请人： Samuel Davis , Eric Smith , Tong Zhang , Supriya Patel
发明人： Samuel Davis , Eric Smith , Tong Zhang , Supriya Patel
IPC分类号： C07K16/28
CPC分类号： C07K16/2809 , C07K16/2803 , C07K16/2887 , C07K2317/24 , C07K2317/31 , C07K2317/526 , C07K2317/53 , C07K2317/71 , C07K2317/732 , C07K2317/90
摘要： The invention provides antibody heavy chain constant regions with a hinge region modified to reduce binding to Fcγ receptors. The modification occurs within positions 233-236 by replacement of natural residues by glycine(s) and/or deletion(s). Such modifications can reduce binding of an antibody bearing such a constant region to Fcγ receptors to background levels. The constant regions can be incorporated into any format of antibody or Fc fusion protein. Such antibodies or fusion proteins can be used in methods of treatment, particularly those in which the mechanisms of action of the antibody or Fc fusion protein is not primarily or at all dependent on effector functions, as is the case when an antibody inhibits a receptor-ligand interaction or agonizes a receptor.

87. 发明授权

US09789612B2 Remotely operating a mobile robot 有权
公开(公告)号：US09789612B2
公开(公告)日：2017-10-17
申请号：US15457671
申请日：2017-03-13
申请人： Orin P. F. Hoffman , Peter Keefe , Eric Smith , John Wang , Andrew Labrecque , Brett Ponsler , Susan Macchia , Brian J. Madge
发明人： Orin P. F. Hoffman , Peter Keefe , Eric Smith , John Wang , Andrew Labrecque , Brett Ponsler , Susan Macchia , Brian J. Madge
IPC分类号： G05B19/04 , B25J13/00 , B25J5/00 , B25J9/16 , B25J13/06 , B25J19/02 , G05D1/00
CPC分类号： B25J13/006 , B25J5/005 , B25J5/007 , B25J9/161 , B25J9/1671 , B25J9/1689 , B25J9/1697 , B25J13/025 , B25J13/06 , B25J19/021 , B25J19/04 , G05B2219/39449 , G05B2219/39451 , G05D1/0038 , G05D2201/0209 , Y10S901/47
摘要： A method of operating a robot includes electronically receiving images and augmenting the images by overlaying a representation of the robot on the images. The robot representation includes user-selectable portions. The method includes electronically displaying the augmented images and receiving an indication of a selection of at least one user-selectable portion of the robot representation. The method also includes electronically displaying an intent to command the selected at least one user-selectable portion of the robot representation, receiving an input representative of a user interaction with at least one user-selectable portion, and issuing a command to the robot based on the user interaction.

88. 发明申请

US20120280563A1 TIME-DOMAIN MULTIPLEXING OF POWER AND DATA 有权
标题翻译：功率和数据的时域多路复用
公开(公告)号：US20120280563A1
公开(公告)日：2012-11-08
申请号：US13286982
申请日：2011-11-01
申请人： Eric Smith , Bryan R. Hinch , Tommee So
发明人： Eric Smith , Bryan R. Hinch , Tommee So
IPC分类号： H02J3/00 , H01H35/00
CPC分类号： H02J7/007 , G06F1/263 , Y10T307/858
摘要： Circuits, methods, and apparatus that may allow an electronic device to control a power adapter. One example may provide an electronic system where an electronic device may control a power adapter through a communication channel. Data transferred in the communication channel may include the temperature of the power adapter, the charging capability of the adapter, and other types of data. In one example, power and data may share the same two wires, and the power and data may be time-division multiplexed. That is, the two wires may convey power and data at different times. Another example may include circuitry to detect a connection between the electronic device and the power adapter. Once a connection is detected, power may be transferred from the power adapter to the electronic device. This power transfer may be interrupted on occasion to transfer data between the power adapter to the electronic device.
摘要翻译：可允许电子设备控制电源适配器的电路，方法和设备。一个示例可以提供电子系统，其中电子设备可以通过通信信道来控制电力适配器。在通信信道中传送的数据可以包括电源适配器的温度，适配器的充电能力以及其他类型的数据。在一个示例中，功率和数据可以共享相同的两条线，并且功率和数据可以被时分复用。也就是说，两条线可以在不同时间传输电力和数据。另一示例可以包括用于检测电子设备和电源适配器之间的连接的电路。一旦检测到连接，电源可能会从电源适配器传输到电子设备。这种电力传输有时可能会在电源适配器与电子设备之间传输数据。

89. 发明申请

US20120195080A1 HIGH-VOLTAGE REGULATED POWER SUPPLY 有权
标题翻译：高压调节电源
公开(公告)号：US20120195080A1
公开(公告)日：2012-08-02
申请号：US13090128
申请日：2011-04-19
申请人： Eric Smith , P. Jeffrey Ungar , Heather R. Sullens
发明人： Eric Smith , P. Jeffrey Ungar , Heather R. Sullens
IPC分类号： H02M7/10
CPC分类号： H02M7/10
摘要： The disclosed embodiments relate to a power-supply circuit, an electronic device that includes the power-supply circuit, and a method for generating high-voltage DC power from AC line power using the power-supply circuit. This power-supply circuit includes a voltage multiplier and a low dropout (LDO) regulator, and does not include a step-up transformer. Conventional power supplies often use a custom step-up transformer, which is expensive unless the power supplies are manufactured in high quantities. In contrast, one embodiment of the present disclosure provides a solid-state implementation of a 700 V regulated power supply that can take up to a 1020 V input from an 6× voltage multiplier powered from the AC mains. Hence, the disclosed power-supply circuit eliminates the need for large, heavy and expensive step-up transformers and chokes that are used in conventional high-voltage DC power supplies.
摘要翻译：所公开的实施例涉及电源电路，包括电源电路的电子设备以及使用电源电路从AC线路电力产生高压DC电力的方法。该电源电路包括电压倍增器和低压差（LDO）调节器，并且不包括升压变压器。常规电源通常使用定制的升压变压器，这是非常昂贵的，除非电源大量生产。相比之下，本公开的一个实施例提供了700V稳压电源的固态实现，其可以从由AC电源供电的6×电压倍增器采用高达1020V的输入。因此，所公开的电源电路消除了对常规高压直流电源中使用的大型，重型和昂贵的升压变压器和扼流器的需要。

90. 发明申请

US20120045440A1 METHOD OF TREATING RHEUMATOID ARTHRITIS WITH AN ANTI-IL-6R ANTIBODY 有权
标题翻译：用抗IL-6R抗体治疗恶性肿瘤的方法
公开(公告)号：US20120045440A1
公开(公告)日：2012-02-23
申请号：US13286261
申请日：2011-11-01
申请人： Allen Radin , Sean Stevens , Tammy T. Huang , Joel H. Martin , Jeanette L. Fairhurst , Ashique Rafique , Eric Smith , Kevin J. Pobursky , Nicholas J. Papadopoulos , James P. Fandl , Gang Chen , Margaret Karow
发明人： Allen Radin , Sean Stevens , Tammy T. Huang , Joel H. Martin , Jeanette L. Fairhurst , Ashique Rafique , Eric Smith , Kevin J. Pobursky , Nicholas J. Papadopoulos , James P. Fandl , Gang Chen , Margaret Karow
IPC分类号： A61K39/395 , A61P19/02
CPC分类号： A61K39/3955 , A61K31/4706 , A61K31/519 , A61K31/655 , A61K38/191 , A61K39/39541 , A61K39/39558 , A61K45/06 , A61K2039/505 , C07K16/248 , C07K16/2866 , C07K2317/21 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92 , Y10S514/885 , A61K2300/00
摘要： The present invention provides methods of preventing or treating rheumatoid arthritis using a fully human antibody or antigen-binding fragment thereof that specifically binds human interleukin-6 receptor (hIL-6R). The methods of the present invention may include administration of a second therapeutic agent, such as one or more of a non-steroidal anti-inflammatory drug (NSAID), a glucocorticoid, a disease-modifying anti-rheumatic drug (DMARD), or a TNF-alpha antagonist, T-cell blocker, anti-CD20 antibody, an IL-1, JAK or IL-17 antagonist, or any combination thereof.
摘要翻译：本发明提供使用特异性结合人白细胞介素-6受体（hIL-6R）的完全人抗体或其抗原结合片段预防或治疗类风湿性关节炎的方法。本发明的方法可以包括施用第二治疗剂，例如非甾体抗炎药（NSAID），糖皮质激素，疾病缓解性抗风湿药（DMARD）中的一种或多种，或 TNF-α拮抗剂，T细胞阻断剂，抗CD20抗体，IL-1，JAK或IL-17拮抗剂或其任何组合。

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