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81. 发明申请

US20100317998A1 Valve Mechanism for Tetherless Biopsy Device 有权
标题翻译：无栓塞活检装置的瓣膜机制
公开(公告)号：US20100317998A1
公开(公告)日：2010-12-16
申请号：US12541437
申请日：2009-08-14
申请人： John A. Hibner , Patrick A. Mescher , Edward A. Rhad
发明人： John A. Hibner , Patrick A. Mescher , Edward A. Rhad
IPC分类号： A61B10/02
CPC分类号： A61B10/0275 , A61B10/0096 , A61B10/0283 , A61B2010/0208
摘要： A biopsy device comprises a body, a needle, a cutter, and a shuttle valve slider. The needle has a first lumen and a second lumen. The cutter translates relative to the needle. The shuttle valve slider translates in response to translation of the cutter. The shuttle valve slider vents the second lumen when the shuttle valve slider is in a first longitudinal position and substantially seals the second lumen relative to atmospheric air when the shuttle valve slider is in a second longitudinal position. A degree of lost motion is provided between the cutter and the shuttle valve slider, such that the cutter moves the shuttle valve slider only when the cutter moves through a first part of the cutter's range of motion; and such that the cutter does not move the shuttle valve slider when the cutter moves through a second part of the cutter's range of motion.
摘要翻译：活检装置包括主体，针，切割器和梭阀滑块。针头具有第一腔和第二腔。切割器相对于针转动。梭阀滑块可根据切刀的平移而平移。当梭阀滑块处于第一纵向位置时，梭阀滑块排出第二内腔，并且当梭阀滑块处于第二纵向位置时，梭阀滑块能够相对于大气空气基本上密封第二腔。在切割器和梭阀滑块之间提供了一定程度的运动，使得切割器仅在切割器移动通过切割器的运动范围的第一部分时移动梭阀滑块; 并且使得当切割器移动通过切割器的运动范围的第二部分时，切割器不移动梭阀滑块。

82. 发明申请

US20100317997A1 Tetherless Biopsy Device with Reusable Portion 有权
标题翻译：无可重复使用部分无栓塞活检装置
公开(公告)号：US20100317997A1
公开(公告)日：2010-12-16
申请号：US12483305
申请日：2009-06-12
申请人： John A. Hibner , Patrick A. Mescher , Edward A. Rhad
发明人： John A. Hibner , Patrick A. Mescher , Edward A. Rhad
IPC分类号： A61B10/02
CPC分类号： A61B10/0275 , A61B10/0096 , A61B10/0283 , A61B2010/0208
摘要： A biopsy device comprises a body, a needle, and a cutter actuation mechanism. The needle extends distally from the body. The cutter actuation mechanism rotates and translates the cutter relative to the body and relative to the needle. The cutter has an overmold presenting a lead screw and a hex portion. The cutter actuation mechanism comprises a first gear disposed about the hex portion of the overmold and a second gear engaged with the lead screw of the overmold by a nut that is integral with the second gear. The cutter actuation mechanism is operable to simultaneously rotate the first gear relative to the body at a first rotational speed and the second gear relative to the body at a second rotational speed. With the lead screw and the nut rotating at different rotational speeds, the lead screw rotates relative to the nut at a third rotational speed.
摘要翻译：活检装置包括主体，针和切割器致动机构。针从身体向远处延伸。切割器致动机构使刀具相对于主体相对于针旋转并平移。刀具具有一个包含一个导螺杆和一个十六进制部分的二次模型。切割器致动机构包括围绕包覆模制件的六边形部分设置的第一齿轮和通过与第二齿轮成一体的螺母与包覆模制体的导螺杆啮合的第二齿轮。切割器致动机构可操作以在第一旋转速度下相对于主体同时旋转第一齿轮，并且第二齿轮以第二旋转速度相对于主体旋转。利用导螺杆和螺母以不同的转速旋转，导螺杆以第三转速相对于螺母旋转。

83. 发明授权

US07826883B2 Localization mechanism for an MRI compatible biopsy device 有权
标题翻译： MRI兼容活检装置的定位机制
公开(公告)号：US07826883B2
公开(公告)日：2010-11-02
申请号：US10171330
申请日：2002-06-12
申请人： John A. Hibner , Gary Todd McCollister , David Denis Beck , David Scott Little
发明人： John A. Hibner , Gary Todd McCollister , David Denis Beck , David Scott Little
IPC分类号： A61B6/02
CPC分类号： A61B10/0275 , A61B5/0555 , A61B17/3403 , A61B90/17 , A61B2010/0208 , A61B2017/00911 , A61B2017/3405 , A61B2017/3411 , A61B2017/347 , A61B2090/3954 , Y10S128/915 , Y10S128/916
摘要： A localization mechanism, or fixture, is used in conjunction with a breast coil for breast compression and for guiding a core biopsy instrument during prone stereotactic biopsy procedures in both open and closed Magnetic Resonance Imaging (MRI) machines. The localization fixture includes a fiducial marker and three-dimensional Cartesian positionable guide for supporting and orienting an MRI-compatible biopsy instrument with detachable probe/thumb wheel probe to the biopsy site of suspicious tissues or lesions.
摘要翻译：定位机构或夹具与乳房线圈结合使用以用于乳房压缩，并用于在开放和闭合的磁共振成像（MRI）机器中的倾斜立体定向活检过程中引导核心活检仪器。本地化夹具包括基准标记和三维笛卡尔定位指南，用于支持和定向具有可拆卸探针/拇指轮探针的MRI兼容活检装置到可疑组织或病变的活检部位。

84. 发明授权

US07758515B2 Biopsy device with integral vacuum assist and tissue sample and fluid capturing canister 有权
标题翻译：具有整体真空辅助和组织样本和流体捕获罐的活检装置
公开(公告)号：US07758515B2
公开(公告)日：2010-07-20
申请号：US11753952
申请日：2007-05-25
申请人： John A. Hibner
发明人： John A. Hibner
IPC分类号： A61B10/00
CPC分类号： A61B10/0275 , A61B10/0283 , A61B2010/0208 , A61B2010/0225
摘要： A biopsy device is provided for obtaining a tissue sample, such as a breast tissue biopsy sample. The biopsy device includes a disposable probe assembly with an outer cannula having a distal piercing tip, a cutter lumen, and a cutter tube that rotates and translates past a side aperture in the outer cannula to sever a tissue sample. The biopsy device also includes a reusable handpiece with an integral motor and power source to make a convenient, untethered control for use with ultrasonic imaging. The reusable handpiece incorporates a probe oscillation mode to assist when inserting the distal piercing tip into tissue. An integral vacuum motor assists prolapsing tissue for effective severing as well as facilitating withdrawal of the tissue samples and bodily fluids from the biopsy site into a detachable,self-contained canister for transporting the separated biopsy samples and fluid for pathology assessment, avoiding biohazards in a clinical setting.
摘要翻译：提供活检装置用于获得诸如乳房组织活组织检查样本的组织样本。活检装置包括具有外插管的一次性探针组件，该外套管具有远端穿刺尖端，切割器内腔和切割管，其旋转并平移穿过外插管中的侧孔以切断组织样本。活检装置还包括具有集成电机和电源的可重复使用的手持件，以便使用于超声波成像的方便，无阻塞的控制。可重复使用的手持件包含探针振动模式，以在将远端穿刺尖端插入组织中时有助于。整体式真空马达帮助脱垂组织进行有效切断，并有利于将组织样本和体液从活组织检查部位抽出到可拆卸的独立罐中，用于运输分离的活检样本和流体进行病理学评估，避免生物危害在临床设置。

85. 发明授权

US07753857B2 Tissue sample serial capturing biopsy device 失效
标题翻译：组织样品连续捕获活检装置
公开(公告)号：US07753857B2
公开(公告)日：2010-07-13
申请号：US11753665
申请日：2007-05-25
申请人： John A. Hibner
发明人： John A. Hibner
IPC分类号： A61B10/00
CPC分类号： A61B10/0275 , A61B10/0283 , A61B2010/0208 , A61B2010/0225
摘要： A biopsy device and method are provided for obtaining a tissue sample, such as a breast tissue biopsy sample. The biopsy device includes a disposable probe assembly with an outer cannula having a distal piercing tip, a cutter lumen, and a cutter tube that rotates and translates past a side aperture in the outer cannula to sever a tissue sample. The biopsy device also includes a reusable handpiece with an integral motor and power source to make a convenient, untethered control for use with ultrasonic imaging. The reusable handpiece incorporates a probe oscillation mode to assist when inserting the distal piercing tip into tissue. The motor also actuates an attached tape indexing mechanism in coordination with movement of the cutter tube to provide sequentially stored tissue samples in a replaceable serial stacking assembly.
摘要翻译：提供活检装置和方法来获得诸如乳房组织活组织检查样本的组织样本。活检装置包括具有外插管的一次性探针组件，该外套管具有远端穿刺尖端，切割器内腔和切割管，其旋转并平移穿过外插管中的侧孔以切断组织样本。活检装置还包括具有集成电机和电源的可重复使用的手持件，以便使用于超声波成像的方便，无阻塞的控制。可重复使用的手持件包含探针振动模式，以在将远端穿刺尖端插入组织中时有助于。电动机还与切割管的运动协调地启动附着的带分度机构，以将顺序存储的组织样本提供在可更换的串联堆叠组件中。

86. 发明申请

US20100160819A1 Biopsy Device with Central Thumbwheel 审中-公开
标题翻译：带中央指轮的活检装置
公开(公告)号：US20100160819A1
公开(公告)日：2010-06-24
申请号：US12337942
申请日：2008-12-18
申请人： Shailendra K. Parihar , John A. Hibner , Andrew P. Nock , Wells D. Haberstich , Gregory W. Johnson , Jessica P. Leimbach , Michael R. Ludzack
发明人： Shailendra K. Parihar , John A. Hibner , Andrew P. Nock , Wells D. Haberstich , Gregory W. Johnson , Jessica P. Leimbach , Michael R. Ludzack
IPC分类号： A61B10/02
CPC分类号： A61B10/0275 , A61B10/0283 , A61B2010/0208 , A61B2010/0225 , A61B2090/0813
摘要： A biopsy device comprises a probe and a holster. The probe has a distally extending needle and a central thumbwheel coupled with the needle. The needle has a transverse tissue receiving aperture. A cutter is translatable relative to the needle to sever tissue protruding through the aperture. The central thumbwheel is manually operable to rotate the needle to reorient the angular position of the aperture about the longitudinal axis defined by the needle. The central thumbwheel is positioned coaxially with the longitudinal axis. An elongate sleeve unitarily couples the needle with the central thumbwheel. A cable driven mechanism in the holster drives the cutter. A rotatable tissue sample holder is coupled with the probe, and has chambers configured to receive tissue samples communicated proximally through a lumen defined by the cutter. A piezoelectric motor in the holster drives the tissue sample holder.
摘要翻译：活检装置包括探针和皮套。探针具有远端延伸的针和与针连接的中心指轮。针具有横向组织接收孔。刀具相对于针可平移以切断通过孔突出的组织。中心指轮可手动操作以旋转针来重新定位围绕由针定义的纵向轴线的孔的角位置。中心指轮与纵向轴线同轴设置。细长的套筒将针与中央指轮整体地连接起来。皮套中的电缆驱动机构驱动切割器。可旋转的组织样本保持器与探针联接，并且具有被配置为接收通过由切割器限定的内腔近端连通的组织样本的腔室。皮套中的压电马达驱动组织样本保持器。

87. 发明申请

US20100160817A1 Control Module Interface for MRI Biopsy Device 有权
标题翻译： MRI活检装置的控制模块接口
公开(公告)号：US20100160817A1
公开(公告)日：2010-06-24
申请号：US12337814
申请日：2008-12-18
申请人： Shailendra K. Parihar , Todd M. Dahling , Patrick A. Mescher , John A. Hibner , Trevor W. V. Speeg , Jessica P. Leimbach , Raj G. Raghavendran , Gavin M. Monson
发明人： Shailendra K. Parihar , Todd M. Dahling , Patrick A. Mescher , John A. Hibner , Trevor W. V. Speeg , Jessica P. Leimbach , Raj G. Raghavendran , Gavin M. Monson
IPC分类号： A61B10/02
CPC分类号： A61B10/04 , A61B5/055 , A61B10/0266 , A61B10/0275 , A61B10/0283 , A61B17/3403 , A61B2010/0208 , A61B2010/045 , A61B2017/00017 , A61B2017/00199 , A61B2017/00221 , A61B2017/00911 , G01R33/285
摘要： A biopsy system includes a first external device, a second external device and a control module interface. The control module interface is in electrical communication with both the first and second external devices, and the control module interface is in mechanical communication with the second external device. The control module interface is configured to be positioned remotely from at least one of the first and second external devices. The control module interface comprises a motor, operational electronics, a shaft connector assembly, an electrical connector and a cabinet configured to house the motor and operational electronics. The motor is in mechanical communication with the second external device via a mechanical cable. The operational electronics are configured to permit control of the motor and a motorized component of the second external device. In some embodiments, the mechanical cable comprises a flexible shaft cable, such as a speedometer cable.
摘要翻译：活检系统包括第一外部设备，第二外部设备和控制模块接口。控制模块接口与第一和第二外部设备电气通信，控制模块接口与第二外部设备进行机械通信。控制模块接口被配置为远离第一和第二外部设备中的至少一个。控制模块接口包括电动机，操作电子设备，轴连接器组件，电连接器和被配置为容纳电动机和操作电子设备的机柜。电机通过机械电缆与第二外部设备进行机械通信。操作电子设备被配置为允许控制电动机和第二外部设备的电动部件。在一些实施例中，机械电缆包括柔性轴电缆，例如速度计电缆。

88. 发明授权

US07693567B2 MRI biopsy apparatus incorporating a sleeve and multi-function obturator 有权
标题翻译：包括套管和多功能闭孔器的MRI活检装置
公开(公告)号：US07693567B2
公开(公告)日：2010-04-06
申请号：US11103718
申请日：2005-04-12
申请人： Mark Tsonton , Timothy G. Dietz , John A. Hibner , Jessica M. Pyzoha , Michael J. Andreyko , Keshava Datta , Michael A. Murray
发明人： Mark Tsonton , Timothy G. Dietz , John A. Hibner , Jessica M. Pyzoha , Michael J. Andreyko , Keshava Datta , Michael A. Murray
IPC分类号： A61B5/05 , A61B10/00
CPC分类号： A61B10/02 , A61B5/055 , A61B5/0555 , A61B10/0041 , A61B10/0233 , A61B10/0275 , A61B10/0283 , A61B17/3403 , A61B17/3417 , A61B17/3421 , A61B90/11 , A61B90/17 , A61B2010/0208 , A61B2010/0225 , A61B2017/00477 , A61B2017/00796 , A61B2017/00911 , A61B2017/3411 , A61B2090/034 , A61B2090/036 , A61B2090/374 , A61B2090/3908 , A61B2090/3933 , A61B2090/3954 , A61B2090/3987
摘要： A localization mechanism, or fixture, is used in conjunction with a breast coil for breast compression and for guiding a core biopsy instrument during prone biopsy procedures in both open and closed Magnetic Resonance Imaging (MRI) machines. The localization fixture includes a three-dimensional Cartesian positionable guide for supporting and orienting an MRI-compatible biopsy instrument, and in particular a sleeve, to a biopsy site of suspicious tissues or lesions. A depth stop enhances accurate insertion, and prevents over-insertion or inadvertent retraction of the sleeve. The sleeve receives a probe of the MRI-compatible biopsy instrument and may contain various features to enhance its imagability, to enhance vacuum and pressure assist therethrough, and marker deployment etc.
摘要翻译：定位机构或夹具与乳房线圈一起用于乳房压缩，并用于在开放和闭合的磁共振成像（MRI）机器中的易行活检过程中引导核心活检仪器。定位固定装置包括一个三维笛卡尔定位指南，用于支持和定向MRI兼容的活检仪器，特别是套筒，用于可疑组织或病变的活检部位。深度限位器可以提高精确的插入，并防止套筒的过度插入或无意的收回。袖子接受MRI兼容活检器械的探头，并且可以包含各种特征以增强其成像能力，以增强通过其中的真空和压力辅助以及标记部署等。

89. 发明授权

US07670338B2 Device for tissue removal 有权
标题翻译：组织去除装置
公开(公告)号：US07670338B2
公开(公告)日：2010-03-02
申请号：US11040711
申请日：2005-01-21
申请人： Thomas E. Albrecht , John A. Hibner , Elizabeth L. Sebern
发明人： Thomas E. Albrecht , John A. Hibner , Elizabeth L. Sebern
IPC分类号： A61B18/14 , A61B10/00
CPC分类号： A61B18/14 , A61B10/02 , A61B2018/00601 , A61B2018/1407
摘要： An excisional biopsy method is disclosed. The method can include rotating an arcuate shaped electrode around a tissue specimen, and drawing a sheath around the tissue specimen as the specimen is cut from a tissue mass. In one embodiment, the method includes tunneling to a tissue site with one electrode, and cutting with a second electrode to obtain the tissue specimen.
摘要翻译：公开了切除活检方法。该方法可以包括围绕组织样本旋转弧形电极，以及当组织块切割样本时在组织样本周围绘制鞘。在一个实施例中，该方法包括用一个电极隧穿到组织部位，并用第二电极切割以获得组织标本。

90. 发明授权

US07611474B2 Core sampling biopsy device with short coupled MRI-compatible driver 有权
标题翻译：具有短耦合MRI兼容驱动程序的核心取样活检装置
公开(公告)号：US07611474B2
公开(公告)日：2009-11-03
申请号：US11025556
申请日：2004-12-29
申请人： John A. Hibner , Kevin D. Predmore , Lawrence Bullen , Vincent J. Contini , James E. Dvorsky , Eric R. Navin
发明人： John A. Hibner , Kevin D. Predmore , Lawrence Bullen , Vincent J. Contini , James E. Dvorsky , Eric R. Navin
IPC分类号： A61B10/00
CPC分类号： A61B10/0266 , A61B10/0283 , A61B2017/00535 , A61B2017/00539 , A61B2017/00544
摘要： A core sampling biopsy device is compatible with use in a Magnetic Resonance Imaging (MRI) environment by being driven by either a pneumatic rotary motor or a piezoelectric drive motor. The core sampling biopsy device obtains a tissue sample, such as a breast tissue biopsy sample, for diagnostic or therapeutic purposes. The biopsy device may include an outer cannula having a distal piercing tip, a cutter lumen, a side tissue port communicating with the cutter lumen, and at least one fluid passageway disposed distally of the side tissue port. The inner cutter may be advanced in the cutter lumen past the side tissue port to sever a tissue sample. A cutter drive assembly maintains a fixed gear ratio relationship between a cutter rotation speed and translation speed of the inner cutter regardless of the density of the tissue encountered to yield consistent sample size.
摘要翻译：核心采样活检装置通过由气动旋转电机或压电驱动电机驱动，与磁共振成像（MRI）环境中的使用兼容。核心采样活检装置获得组织样本，例如乳腺组织活检样本，用于诊断或治疗目的。活检装置可以包括具有远端穿刺尖端，切割器腔，与切割器腔连通的侧组织端口以及至少一个流体通道的外套管，该至少一个流体通道设置在侧组织端口的远侧。内切割器可以在切割器腔中前进通过侧组织端口以切断组织样品。切割器驱动组件保持切割器旋转速度和内切割器的平移速度之间的固定齿轮比关系，而与所遇到的组织的密度无关，以产生一致的样本尺寸。

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