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81. 发明申请

US20110315621A1 DECANTING CENTRIFUGE WITH PLURAL SCREEN SUPPORT SECTIONS 有权
标题翻译：用多个屏幕支持部分决定离散度
公开(公告)号：US20110315621A1
公开(公告)日：2011-12-29
申请号：US13141980
申请日：2009-12-22
申请人： Trevor Heley , John Wright
发明人： Trevor Heley , John Wright
IPC分类号： B04B7/18 , B04B3/04
CPC分类号： B04B3/04 , B04B7/16
摘要： A screen bowl decanting centrifuge comprising a rotatable bowl (4) and a conveyor assembly (8) adapted, in use, to separate a slurry into solids and liquids components, and an outlet for the liquids component which outlet communicates with the inlet (102) of a perforated bowl section (100) arranged, in use, to filter the liquids component as it passes through the perforations of a screen or screens (13), wherein the perforated bowl section (100) comprises a plurality of removably mounted screen support sections (50).
摘要翻译：一种筛碗倾析离心机，包括可旋转碗（4）和输送机组件（8），所述输送机组件（8）在使用中适于将浆料分离成固体和液体组分，以及出口与入口（102）连通的液体组分，穿孔碗部分（100），其布置成在使用中过滤液体组分，当其穿过筛网（13）的穿孔时，其中多孔碗部分（100）包括多个可移除地安装的筛网支撑部分（50）。

82. 发明申请

US20090049314A1 Method and System for Dynamic Voltage and Frequency Scaling (DVFS) 审中-公开
标题翻译：动态电压和频率缩放方法与系统（DVFS）
公开(公告)号：US20090049314A1
公开(公告)日：2009-02-19
申请号：US12190029
申请日：2008-08-12
申请人： Ali Taha , Sani Gosali , Zhijun Gong , Nelson Sollenberger , John Wright
发明人： Ali Taha , Sani Gosali , Zhijun Gong , Nelson Sollenberger , John Wright
IPC分类号： G06F1/00
CPC分类号： G06F1/3203 , G06F1/324 , G06F1/3296 , Y02D10/126 , Y02D10/172
摘要： Methods and systems for dynamic voltage and frequency scaling (DVFS) may include monitoring change in resource utilization of an electronic device. If the change is greater than a threshold amount, a frequency of at least one clock and/or voltage for at least one voltage island may be adjusted. The resource utilization may be measured as, for example, a number of instructions executed per second. The frequency and/or voltage adjustment may depend on one or more operating points that may correspond to a power management state. An interrupt received in a power management state may also indicate an operating point. If resource utilization has increased, the frequency/voltage may be increased. Similarly, in cases where resource utilization has decreased, the frequency/voltage may be decreased. Voltage to circuits using the clock may be increased prior to increasing the clock frequency, and the voltage may be decreased after decreasing the clock frequency.
摘要翻译：用于动态电压和频率缩放（DVFS）的方法和系统可以包括监测电子设备的资源利用的变化。如果该变化大于阈值，则可调整至少一个电压岛的至少一个时钟和/或电压的频率。资源利用可以被测量为例如每秒执行的指令的数量。频率和/或电压调节可以取决于可对应于功率管理状态的一个或多个工作点。在电源管理状态下接收到的中断也可以指示操作点。如果资源利用率增加，频率/电压可能会增加。类似地，在资源利用率下降的情况下，可以降低频率/电压。使用时钟的电路的电压可以在增加时钟频率之前增加，并且可以在降低时钟频率之后降低电压。

83. 发明申请

US20070243615A1 Methods for producing preparations of recombinant AAV virions substantially free of empty capsids 有权
标题翻译：用于制备基本上不含空衣壳的重组AAV病毒体的制备方法
公开(公告)号：US20070243615A1
公开(公告)日：2007-10-18
申请号：US11809655
申请日：2007-06-01
申请人： Guang Qu , John Wright
发明人： Guang Qu , John Wright
IPC分类号： C12N15/861
CPC分类号： C12N15/86 , C12N7/00 , C12N2750/14143 , C12N2750/14151
摘要： Methods for separating AAV empty capsids from mixtures of AAV vector particles and AAV empty capsids are described. The methods use column chromatography techniques and provide for commercially viable levels of recombinant AAV virions.
摘要翻译：描述了从AAV载体颗粒和AAV空衣壳的混合物中分离AAV空衣壳的方法。该方法使用柱色谱技术并提供商业上可行的重组AAV病毒粒子水平。

84. 发明申请

US20070151235A1 Actuator system having a valve manifold 有权
标题翻译：具有阀歧管的致动器系统
公开(公告)号：US20070151235A1
公开(公告)日：2007-07-05
申请号：US11325370
申请日：2006-01-03
申请人： John Wright
发明人： John Wright
IPC分类号： F16D31/02
CPC分类号： F15B20/002 , F15B2211/20538 , F15B2211/212 , F15B2211/30505 , F15B2211/3051 , F15B2211/3127 , F15B2211/8623 , F15B2211/8752 , F15B2211/8757
摘要： A block manifold for a fail safe actuator system allows the actuator operation with a hand pump if electrical power were not available. A method is available to isolate fail safe solenoid valves and an accumulator from a hand pump circuit to relieve the stored energy from the fail safe circuit. An additional set of pilot operated check valves were installed between the motor driven pump circuit and the hand pump circuit. These pilot operated check valves isolated the hand pump circuit from the fail safe dump solenoid and accumulator. These pilot actuated check valves also hold the actuator in the fail safe position as long as the hand pump system was not used. There is also a hydraulic bleed circuit to relieve the accumulator stored energy when the hand pump system was used.
摘要翻译：用于故障安全执行器系统的块歧管允许在没有电力的情况下使用手动泵进行执行器操作。一种方法可用于隔离来自手动泵电路的故障安全电磁阀和蓄能器，以便从故障安全回路中释放存储的能量。在电机驱动泵电路和手动泵电路之间安装了一组先导式止回阀。这些先导式止回阀将手泵电路与故障安全转储电磁阀和蓄电池隔离。只要不使用手动泵系统，这些先导式止回阀也将执行器保持在故障安全位置。当使用手动泵系统时，还有一个液压泄放电路可以缓解蓄能器的储存能量。

85. 发明申请

US20070042154A1 Self-assembled monolayer enhanced DLC coatings 审中-公开
标题翻译：自组装单层增强DLC涂层
公开(公告)号：US20070042154A1
公开(公告)日：2007-02-22
申请号：US11586922
申请日：2006-10-26
申请人： Mehmet Hancer , Jane Gates , Joel Hoehn , Fang Chen , Marsha Huha , John Wright , Lee Walter
发明人： Mehmet Hancer , Jane Gates , Joel Hoehn , Fang Chen , Marsha Huha , John Wright , Lee Walter
IPC分类号： B32B3/02
CPC分类号： C23C26/00 , B05D1/185 , B82Y30/00 , B82Y40/00 , G11B5/3106 , G11B5/72 , G11B5/8408 , Y10T428/21
摘要： A protective coating for a substrate includes a diamond-like carbon (DLC) layer overlying the substrate and having gaps where the substrate is not protected by the diamond-like carbon layer. The protective coating also includes a self-assembled monolayer formed in the gaps of the diamond-like carbon layer.
摘要翻译：用于衬底的保护涂层包括覆盖衬底的类金刚石碳（DLC）层，并且具有衬底未被类金刚石碳层保护的间隙。保护涂层还包括在类金刚石碳层的间隙中形成的自组装单层。

86. 发明申请

US20070021466A1 CCR2 inhibitors and methods of use thereof 审中-公开
标题翻译： CCR2抑制剂及其使用方法
公开(公告)号：US20070021466A1
公开(公告)日：2007-01-25
申请号：US11486395
申请日：2006-07-13
申请人： Solomon Ungashe , John Wright , Andrew Pennell , Zheng Wei , Anita Melikian
发明人： Solomon Ungashe , John Wright , Andrew Pennell , Zheng Wei , Anita Melikian
IPC分类号： A61K31/444 , A61K31/44
CPC分类号： C07D213/50
摘要： Compounds are provided that act as potent antagonists of the CCR2 receptor. These compounds are useful for treating inflammation, a hallmark disease for CCR2. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR2-mediated diseases, and as controls in assays for the identification of CCR2 antagonists.
摘要翻译：提供了作为CCR2受体的有效拮抗剂的化合物。这些化合物可用于治疗炎症，CCR2的标志性疾病。化合物通常为芳基磺酰胺衍生物，并且可用于药物组合物，用于治疗CCR2介导的疾病的方法，以及用于鉴定CCR2拮抗剂的测定中的对照。

87. 发明申请

US20060267343A1 Pipe coupling 审中-公开
标题翻译：管接头
公开(公告)号：US20060267343A1
公开(公告)日：2006-11-30
申请号：US11489487
申请日：2006-07-20
申请人： John Wright
发明人： John Wright
IPC分类号： F16L21/06
CPC分类号： F16L21/08 , F16L17/04 , F16L21/005
摘要： The invention relates to a pipe coupling for rigid plastics pipes having smooth cylindrical ends. The coupling includes a rigid sleeve having a longitudinal bore. Two spaced apart annular grooves are provided in the bore to respectively house deformable annular seals adjacent the ends of the sleeve. O-rings will be used as seals. A harness is securable over the sleeve with pipe engaging teeth adjacent each of the opposite ends. The harness is split longitudinally with a cylindrical passage having an annular recess to receive the sleeve. The teeth are formed by serrated ridges, preferably screw threads, in the passage extending from the recess to the outer ends of the passage. Corresponding lateral lugs on each half of the harness have bolt holes for assembly of the harness over the sleeve. The coupling is particularly suited for connecting plastics pipes used to convey backfill, normally in underground mining operations.
摘要翻译：本发明涉及一种具有光滑圆柱端的刚性塑料管的管接头。联轴器包括具有纵向孔的刚性套筒。在孔中设置两个间隔开的环形槽，以分别容纳与套筒端部相邻的可变形环形密封件。 O形圈将用作密封件。线束可以在套筒上固定，管子与相邻端部相邻的齿相啮合。线束纵向分开，圆柱形通道具有环形凹槽以接收套筒。齿在通道中从凹槽延伸到通道的外端的通道中形成有锯齿状的脊，优选是螺纹。线束的每一半上的相应的横向凸耳具有用于将线束组装在套筒上的螺栓孔。联轴器特别适用于连接用于传送回填物的塑料管道，通常在地下采矿作业中。

88. 发明申请

US20060245110A1 Head assembly having a sensing element to provide feedback for head-media instability 有权
公开(公告)号：US20060245110A1
公开(公告)日：2006-11-02
申请号：US11115659
申请日：2005-04-27
申请人： Jorge Hanchi , Dian Song , John Wright , Andrew White
发明人： Jorge Hanchi , Dian Song , John Wright , Andrew White
IPC分类号： G11B5/60
CPC分类号： G11B5/6005 , G11B5/6058 , G11B5/607 , G11B5/6076
摘要： A head assembly having a sensor element on the head assembly. Embodiments of the sensor element are configured to detect non-contact induced head-media interface instability, “onset of contact” or low level interference. The non-contact head-media instability or interference is detected based upon sensor feedback relating to excitation of the air bearing resonance modes of the slider body. In embodiments of the present invention, the sensor head assembly includes a microactuator which is energizable to microactuate the head or transducer elements on the head assembly.

89. 发明申请

US20060227463A1 Suspension assembly with molded structures 有权
标题翻译：具有模制结构的悬挂组件
公开(公告)号：US20060227463A1
公开(公告)日：2006-10-12
申请号：US11102055
申请日：2005-04-08
申请人： John Wright , Jagdish Agrawal , Zine-Eddine Boutaghou , Joseph Sassine , Andrew White
发明人： John Wright , Jagdish Agrawal , Zine-Eddine Boutaghou , Joseph Sassine , Andrew White
IPC分类号： G11B5/48
CPC分类号： G11B5/4833
摘要： A support assembly includes a base layer, a circuit defined along the base layer, and a first material molded on at least a portion of the base layer. The first material substantially forms a shape of at least a portion of the support assembly. Further disclosed is a molded suspension assembly. The molded suspension assembly includes a thin and elongate metallic substrate and a non-metallic material molded along at least a portion of one side of the metallic substrate. The non-metallic material interlocks with the metallic substrate. The molded suspension assembly includes a transducer support area at or near a first end of the molded suspension assembly.
摘要翻译：支撑组件包括基底层，沿基底层限定的电路以及模制在基底层的至少一部分上的第一材料。第一材料基本上形成支撑组件的至少一部分的形状。进一步公开的是模制悬挂组件。模制的悬挂组件包括薄且细长的金属基底和沿着金属基底的一侧的至少一部分模制的非金属材料。非金属材料与金属基底互锁。模制的悬挂组件包括在模制的悬挂组件的第一端处或附近的换能器支撑区域。

90. 发明申请

US20060111351A1 Aryl sulfonamides 审中-公开
公开(公告)号：US20060111351A1
公开(公告)日：2006-05-25
申请号：US11255163
申请日：2005-10-20
申请人： Solomon Ungashe , John Wright , Andrew Pennell , Zheng Wei , Anita Melikian
发明人： Solomon Ungashe , John Wright , Andrew Pennell , Zheng Wei , Anita Melikian
IPC分类号： A61K31/5377 , C07D413/02
CPC分类号： C07D213/50 , C07D213/26 , C07D213/52 , C07D213/70 , C07D213/74 , C07D213/84 , C07D213/89 , C07D241/12 , C07D405/12 , C07D413/12
摘要： Compounds are provided that act as potent antagonists of the CCR9 receptor, and which have been further confirmed in animal testing for inflammation, one of the hallmark disease states for CCR9. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR9-mediated diseases, and as controls in assays for the identification of CCR9 antagonists.

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