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81. 发明申请

US20050074470A1 Compounds, methods and pharmaceutical compositions for treating cellular damage, such as neural or cardiovascular tissue damage 失效
标题翻译：用于治疗细胞损伤的化合物，方法和药物组合物，例如神经或心血管组织损伤
公开(公告)号：US20050074470A1
公开(公告)日：2005-04-07
申请号：US10772235
申请日：2004-02-06
申请人： Jia-He Li , Jie Zhang
发明人： Jia-He Li , Jie Zhang
IPC分类号： A61K9/20 , A61K9/48 , A61K31/436 , A61K31/4453 , A61K31/496 , A61K31/499 , A61K31/5377 , A61K31/662 , A61K47/34 , A61P1/00 , A61P3/10 , A61P7/00 , A61P9/00 , A61P9/10 , A61P13/12 , A61P17/00 , A61P17/02 , A61P19/00 , A61P19/02 , A61P19/10 , A61P21/00 , A61P21/04 , A61P25/00 , A61P25/02 , A61P25/04 , A61P25/14 , A61P25/16 , A61P25/28 , A61P27/02 , A61P29/00 , A61P31/18 , A61P35/00 , A61P35/02 , A61P35/04 , A61P37/02 , C07D237/26 , C07D491/06 , C07F9/6533 , C07F9/6561 , A61K9/00
CPC分类号： C07D491/06 , C07D237/26 , C07F9/6561
摘要： This invention relates to compounds, pharmaceutical compositions, and methods of using the disclosed compounds for inhibiting PARP.
摘要翻译：本发明涉及化合物，药物组合物和使用所公开的化合物抑制PARP的方法。

82. 发明申请

US20050020595A1 Compounds, methods and pharmaceutical compositions for inhibiting PARP 有权
标题翻译：用于抑制PARP的化合物，方法和药物组合物
公开(公告)号：US20050020595A1
公开(公告)日：2005-01-27
申请号：US10853714
申请日：2004-05-26
申请人： Vincent Kalish , Jie Zhang , Weizheng Xu , Jia-He Li , Amy Xing , Qun Liu
发明人： Vincent Kalish , Jie Zhang , Weizheng Xu , Jia-He Li , Amy Xing , Qun Liu
IPC分类号： A61K20060101 , A61K31/495 , A61K31/5025 , A61K31/675 , C07D487/04 , C07D491/04 , C07F9/6561
CPC分类号： C07D487/06 , C07D471/06 , C07D491/06 , C07D491/08
摘要： The present invention provides compounds which inhibit poly(ADP-ribose) polymerase (“PARP”), compositions containing these compounds and methods for using these PARP inhibitors to treat, prevent and/or ameliorate the effects of the conditions described herein.
摘要翻译：本发明提供抑制聚（ADP-核糖）聚合酶（“PARP”）的化合物，含有这些化合物的组合物和使用这些PARP抑制剂治疗，预防和/或改善本文所述病症的作用的方法。

83. 发明授权

US06603141B2 Organic semiconductor and method 失效
标题翻译：有机半导体和方法
公开(公告)号：US06603141B2
公开(公告)日：2003-08-05
申请号：US10034337
申请日：2001-12-28
申请人： Lawrence E. Lach , Steven M. Scheifers , Jie Zhang , Daniel R. Gamota , Paul W. Brazis, Jr.
发明人： Lawrence E. Lach , Steven M. Scheifers , Jie Zhang , Daniel R. Gamota , Paul W. Brazis, Jr.
IPC分类号： H01L2700
CPC分类号： H01L51/0508 , H01L51/0004 , H01L51/0005 , H01L51/0021
摘要： A semiconductor device formed of a flexible or rigid substrate (10) having a gate electrode (11), a source electrode (12), and a drain electrode (13) formed thereon and organic semiconductor material (14) disposed at least partially thereover. With appropriate selection of material, the gate electrode (11) will form a Schottky junction and an ohmic contact will form between the organic semiconductor material (14) and each of the source electrode (12) and drain electrode (13). In many of the embodiments, any of the above elements can be formed through contact or non-contact printing. Sizing of the resultant device can be readily scaled to suit various needs.
摘要翻译：由具有形成在其上的栅电极（11），源电极（12）和漏电极（13）的柔性或刚性基板（10）形成的半导体器件和至少部分地设置在其上的有机半导体材料（14）构成。通过适当选择材料，栅电极（11）将形成肖特基结，在有机半导体材料（14）与源电极（12）和漏电极（13）之间形成欧姆接触。在许多实施例中，可以通过接触或非接触印刷形成任何上述元件。可以容易地缩放所得到的装置的尺寸以适应各种需要。

84. 发明授权

US06387902B1 Phenazine compounds, methods and pharmaceutical compositions for inhibiting PARP 失效
标题翻译：吩嗪化合物，抑制PARP的方法和药物组合物
公开(公告)号：US06387902B1
公开(公告)日：2002-05-14
申请号：US09224293
申请日：1998-12-31
申请人： Jie Zhang , Kevin Leonard Tays , Jia-He Li
发明人： Jie Zhang , Kevin Leonard Tays , Jia-He Li
IPC分类号： A61K3150
CPC分类号： C07D405/12 , C07D241/46 , C07D417/12
摘要： This invention relates to compounds, pharmaceutical compositions, and methods of using compounds of the formula: wherein R1-R9 and Z are independently. hydrogen, hydroxy, halo, haloalkyl, thiocarbonyl, cyano, nitro, amino, imino, alkylamino, aminoalkyl, sulfhydryl, thioalkyl, alkylthio, sulfonyl, alkylsulfonyl, C1-C9 straight or branched chain alkyl, C2-C9 straight or branched chain alkenyl, C2-C9 straight or branched chain alkynyl, C1-C6 straight or branched chain alkoxy, C2-C6 straight or branched chain alkenoxy, C2-C6 straight or branched chain alkynoxy, aryl, carbocycle, heterocycle, aralkyl, alkylaryl, alkylaryloxy, aryloxy, aralkyloxy, aralkylsulfonyl, aralkylamino, arylamino, arylazo, arylthio, or aralkylthio; or Z is wherein U is C or N, and R7 and R8 are defined above; and X and Y are independently aryl, carbocycle, or heterocycle.
摘要翻译：本发明涉及化合物，药物组合物和使用下式化合物的方法：其中R1-R9和Z独立地表示。氢，羟基，卤素，卤代烷基，硫代羰基，氰基，硝基，氨基，亚氨基，烷基氨基，氨基烷基，巯基，硫代烷基，烷硫基，磺酰基，烷基磺酰基，C1-C9直链或支链烷基，C2-C9直链或支链烯基， C 2 -C 9直链或支链炔基，C 1 -C 6直链或支链烷氧基，C 2 -C 6直链或支链烯氧基，C 2 -C 6直链或支链炔氧基，芳基，碳环，杂环，芳烷基，烷基芳基，烷基芳氧基，芳氧基，芳烷氧基，芳烷基磺酰基，芳烷基氨基，芳基氨基，芳基偶氮，芳硫基或芳烷硫基; 或Z是其中U是C或N，并且R7和R8如上定义; X和Y独立地是芳基，碳环或杂环。

85. 发明授权

US06380211B1 Alkoxy-substituted compounds, methods, and compositions for inhibiting PARP activity 失效
标题翻译：用于抑制PARP活性的烷氧基取代的化合物，方法和组合物
公开(公告)号：US06380211B1
公开(公告)日：2002-04-30
申请号：US09711953
申请日：2000-11-15
申请人： Paul F. Jackson , Keith M. Maclin , Jie Zhang
发明人： Paul F. Jackson , Keith M. Maclin , Jie Zhang
IPC分类号： A61K3147
CPC分类号： C07D471/06 , C07D217/22 , C07D217/24 , C07D221/12 , C07D221/18 , C07D237/30 , C07D237/32 , C07D237/34 , C07D239/88 , C07D239/93 , C07D239/94 , C07D475/02 , C07D491/04 , C07F9/6561
摘要： A compound, compositions, methods of use, and processes of making formula I: or a pharmaceutically acceptable salt, hydrate, ester, solvate, prodrug, metabolite, stereoisomer, or mixtures thereof, wherein: R1, when present, is hydrogen or lower alkyl; R2 is lower alkyl, aryl, aralkyl, lower alkanoyl, or —(CH2)n—(CHOH)y(CH2)mA, wherein n is 1-4, y is 0 or 1, m is 0-5, and A is cycloalkyl, cycloalkenyl, lower alkanoyl, aryl, aralkyl, —NH2, —NH—(lower alkyl), Y represents the atoms necessary to form a fused 5- to 6-membered ring that is aromatic or nonaromatic and carbocyclic or heterocyclic; Z is (i) —CHR2CHR3— where R2 and R3 are independently hydrogen, alkyl, aryl or aralkyl; (ii) —R6C═CR3— where R6 and R3 are independently hydrogen, lower alkyl, aryl, aralkyl, chlorine, bromine or —NR7R8, where R7 and R8 are independently hydrogen or lower alkyl, or, R6 and R3, taken together, form a fused 5- to 6-membered ring that is aromatic or nonaromatic and carbocyclic or heterocyclic; (iii) —R2C═N—; (iv) —CR2(OH)—NR7—; or (v) —C(O)—NR7—.
摘要翻译：化合物，组合物，使用方法和制备式I的方法：或其药学上可接受的盐，水合物，酯，溶剂化物，前药，代谢物，立体异构体或其混合物，其中：R 1当存在时为氢或低级烷基或 - （CH 2）n - （CHOH）y（CH 2）mA，其中n为1-4，y为0或1，m为0-5，A为是环烷基，环烯基，低级烷酰基，芳基，芳烷基，-NH 2，-NH-（低级烷基），Y表示形成芳族或非芳族和碳环或杂环的稠合5-至6-元环所必需的原子; Z 是（i）-CHR2CHR3-，其中R2和R3独立地是氢，烷基，芳基或芳烷基;（ii）-R6C = CR3-，其中R6和R3独立地是氢，低级烷基，芳基，芳烷基，氯，溴或-NR7R8 其中R 7和R 8独立地为氢或低级烷基，或者R 6和R 3一起形成芳族或非芳族和碳环或杂环的稠合5-至6-元环;（ⅲ）-R2C = N-; （iv ）-CR2（OH）-NR7-; 或（ⅴ）-C（O）-NR7-。

86. 外观设计

USD1041229S1 Heating stove 有权
公开(公告)号：USD1041229S1
公开(公告)日：2024-09-10
申请号：US29832192
申请日：2022-03-25
申请人： Jie Zhang
设计人： Jie Zhang
摘要： FIG. 1 is a perspective view of a heating stove, showing my new design;
FIG. 2 is another perspective view thereof;
FIG. 3 is a front view thereof;
FIG. 4 is a rear view thereof;
FIG. 5 is a left side view thereof;
FIG. 6 is a right side view thereof;
FIG. 7 is a top plan view thereof;
FIG. 8 is a bottom plan view thereof;
FIG. 9 is an enlarged view of portion of FIG. 1; and,
FIG. 10 is another enlarged view of portion of FIG. 1.
The dash-dash broken lines show portions of the heating stove and form no part of the claimed design. The dot-dash broken lines shown in FIGS. 1, 9 & 10 define the boundary of the enlargement area and form no part of the claimed design.

87. 发明申请

US20160345828A1 SYSTEM AND METHOD FOR MULTI-SCALE CLOSED-LOOP EYE TRACKING WITH REAL-TIME IMAGE MONTAGING 有权
标题翻译：用于实时图像聚合的多尺度闭环眼跟踪的系统和方法
公开(公告)号：US20160345828A1
公开(公告)日：2016-12-01
申请号：US15158803
申请日：2016-05-19
申请人： Qiang Yang , Jie Zhang
发明人： Qiang Yang , Jie Zhang
IPC分类号： A61B3/15 , G02B26/10 , A61B3/12 , A61B3/113 , A61B3/00
CPC分类号： A61B3/152 , A61B3/0025 , A61B3/113 , A61B3/1225 , G02B26/105
摘要： A system for multi-scale closed-loop eye tracking to compensate for translation and rotation motion while imaging in vivo a surface area of an internal structure of an eye of a subject includes a narrow field imaging device optically coupled to an optical path to receive light reflected from the surface area of the structure of the eye. A wide field camera is optically coupled to the optical path by a beam splitter disposed in the optical path. A tracking mirror is disposed in the optical path between the beam splitter and the structure of the eye. A control process algorithm actively compensates substantially in real time for both translational and rotational movements of the eye. A system where a torsional correction device causes a rotating movement of a subject's head and a method for multi-scale closed-loop eye tracking are also described.
摘要翻译：一种用于多尺度闭环眼睛跟踪的系统，用于补偿平移和旋转运动，同时在体内成像对象的眼睛的内部结构的表面区域包括光学耦合到光路以接收光的窄场成像装置从眼睛结构的表面积反射出来。通过设置在光路中的分束器将宽视场摄像机光耦合到光路。跟踪镜设置在分束器和眼睛结构之间的光路中。控制过程算法主动地实时补偿眼睛的平移和旋转运动。还描述了一种系统，其中扭转校正装置引起受试者的头部的旋转运动以及用于多尺度闭环眼睛跟踪的方法。

88. 发明授权

US09346245B2 Laminar composite toilet lid and seat 有权
标题翻译：层压复合马桶盖和座椅
公开(公告)号：US09346245B2
公开(公告)日：2016-05-24
申请号：US13083161
申请日：2011-04-08
申请人： Chengdong Wu , Jie Zhang
发明人： Chengdong Wu , Jie Zhang
IPC分类号： A47K13/14 , B32B21/02 , A47K13/02 , B32B27/30
CPC分类号： B32B21/02 , A47K13/02 , B32B27/308 , B32B2307/412 , B32B2317/12 , B32B2317/16 , B32B2333/12 , B32B2509/00 , Y10T428/24802
摘要： Embodiments of the present disclosure include a laminate composite toilet lid and seat and a method of manufacturing thereof. The toilet lid includes a core structural layer having a shape and size associated with the toilet lid. The toilet lid also includes a first decorative graphic layer disposed on a first surface of the core structural layer. The toilet lid further includes a plurality of exterior layers disposed on exterior surfaces of the core structural layer and the first decorative graphic layer, the exterior layers configured to envelop the toilet lid.
摘要翻译：本公开的实施例包括层压复合马桶盖和座椅及其制造方法。马桶盖包括具有与马桶盖相关联的形状和尺寸的芯结构层。马桶盖还包括设置在芯结构层的第一表面上的第一装饰图形层。马桶盖还包括设置在芯结构层和第一装饰图形层的外表面上的多个外层，外层构造成包封马桶盖。

89. 发明授权

US09205180B2 Method and device for loading medical appliance with medicaments and/or polymers 有权
标题翻译：用药物和/或聚合物装载医疗器具的方法和装置
公开(公告)号：US09205180B2
公开(公告)日：2015-12-08
申请号：US13522819
申请日：2011-01-19
申请人： Jie Zhang , Bo Yi , Changsheng Wu , Zhirong Tang , Qiyi Luo
发明人： Jie Zhang , Bo Yi , Changsheng Wu , Zhirong Tang , Qiyi Luo
IPC分类号： A61L33/00 , A61L31/06 , A61L31/16 , A61F2/91
CPC分类号： A61F2/82 , A61F2/91 , A61F2240/001 , A61F2250/0068 , A61L31/06 , A61L31/16 , A61L2300/416 , B05C21/00 , C08L67/04
摘要： A method and a device for loading a medical appliance with a medicament and/or polymer includes capturing images of a plurality of grooves or holes of the medical appliance using an image capturing device; performing digital image processing on the image of each of the grooves or holes to obtain a pattern of each of the grooves or holes; calculating a central position of the pattern of each of the grooves or holes, and determining a loading position of each of the grooves or holes based on the central position; and adjusting a relative position between a loading device and the medical appliance to align an outlet of the loading device with the loading position of the medical appliance, and loading each of the grooves or holes with the medicament and/or polymer. The method and device can load the medical appliance with the medicament and/or polymer fast and efficiently.
摘要翻译：一种用于装载具有药物和/或聚合物的医疗器具的方法和装置包括使用图像捕获装置捕获医疗器具的多个凹槽或孔的图像; 对每个凹槽或孔的图像执行数字图像处理以获得每个凹槽或孔的图案; 计算每个凹槽或孔的图案的中心位置，以及基于中心位置确定每个凹槽或孔的装载位置; 以及调整加载装置和医疗器具之间的相对位置，以将装载装置的出口与医疗器具的装载位置对齐，并且用药物和/或聚合物装载每个凹槽或孔。该方法和装置可以快速且有效地加载具有药物和/或聚合物的医疗器具。

90. 发明授权

US08869383B2 Method of making magnetics assembly 有权
标题翻译：制作磁性装配的方法
公开(公告)号：US08869383B2
公开(公告)日：2014-10-28
申请号：US13523076
申请日：2012-06-14
申请人： Yong-Chun Xu , Jie Zhang
发明人： Yong-Chun Xu , Jie Zhang
IPC分类号： H01F7/06 , H01F17/06 , H01F27/28
CPC分类号： H01F17/062 , H01F27/2823 , H01F27/2828 , H01F41/07 , H01F41/08 , Y10T29/4902 , Y10T29/49069 , Y10T29/49071 , Y10T29/49073 , Y10T29/49075
摘要： A magnetics assembly (100) including a transformer (1) made of litz wire. The transformer includes a toroid core (2) and a bundle of wires (3) winding around the toroid core. The bundle of wires includes first to eighth wires, and has a central portion with all eight wires twisted together and winding around the toroid core. First and second ends of the bundle of wires oppositely extend out from the toroidal core. The ends of the first to eighth wires are connected to form a primary and a secondary coils of the transformer, wherein the second ends of the first wire and the second wire, and the first ends of the third wire and the fourth wire are sorted out to form central taps (35, 36) of the primary and secondary coils, respectively.
摘要翻译：磁性组件（100）包括由绞合线制成的变压器（1）。变压器包括环形磁芯（2）和缠绕在环形磁芯周围的电线束（3）。电线束包括第一至第八导线，并且具有中心部分，所有八条线绞合在一起并围绕环形芯线缠绕。线束的第一和第二端从环形芯相对地延伸出来。连接第一至第八导线的端部以形成变压器的初级线圈和次级线圈，其中第一线和第二线的第二端以及第三线和第四线的第一端被整理以分别形成初级和次级线圈的中心抽头（35,36）。

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