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81. 发明授权

US5658278A Catheter for RF ablation with cooled electrode and method 失效
标题翻译：用于RF消融的导管用冷却的电极和方法
公开(公告)号：US5658278A
公开(公告)日：1997-08-19
申请号：US381198
申请日：1995-01-31
申请人： Mir A. Imran , Mark L. Pomeranz
发明人： Mir A. Imran , Mark L. Pomeranz
IPC分类号： A61B18/12 , A61B17/00 , A61B18/00 , A61B18/14 , A61B17/39 , A61N1/05
CPC分类号： A61B18/1492 , A61B18/1402 , A61B2017/00084 , A61B2017/003 , A61B2018/00023 , A61B2018/00029 , A61B2018/00035 , A61B2018/00166 , A61B2018/00351 , A61B2018/00577 , A61B2018/00821
摘要： A catheter for radio frequency ablation with a cooled electrode for use in tissue having a surface comprising an elongate member having proximal and distal extremities. A metal conducting electrode secured to the distal extremity of the elongate member and having a chamber therein. A conductor extends through the elongate member from the proximal to the distal extremity for supplying radio frequency energy to the electrode. The elongate member has a lumen in the distal extremity which is in communication with the chamber. A coolant is disposed in the chamber and in contact with the electrode for dissipating heat created in the electrode by the application of radio frequency energy thereto.
摘要翻译：一种用于射频消融的导管，其具有用于组织的冷却电极，其具有包括具有近端和远端的细长构件的表面。金属导电电极固定到细长构件的远端并且在其中具有室。导体从近端延伸穿过细长构件到远端，用于向电极提供射频能量。细长构件具有与腔室连通的远端末端的内腔。冷却剂设置在室中并与电极接触，用于通过对其施加射频能量来散发在电极中产生的热量。

82. 发明授权

US5626593A Flexible elongate device having a distal extremity with a vibratory impact tip and method 失效
标题翻译：具有远端的柔性细长装置，其具有振动冲击尖端和方法
公开(公告)号：US5626593A
公开(公告)日：1997-05-06
申请号：US444311
申请日：1995-05-18
申请人： Mir A. Imran
发明人： Mir A. Imran
IPC分类号： A61B17/00 , A61B17/22 , A61M25/00 , A61M25/01 , A61M25/08
CPC分类号： A61B17/2202 , A61M25/0113 , A61M25/09041 , A61B2017/22094
摘要： A flexible elongate device including a flexible elongate tubular member having proximal and distal extremities. A flexible coil spring is provided having proximal and distal extremities. The proximal extremity of the coil spring is secured to the distal extremity of the flexible elongate tubular member. A rounded tip is secured to the distal extremity of the coil spring. A flexible elongate element having proximal and distal extremities is disposed within said coil spring and extends longitudinally of the coil spring. The distal extremity of the flexible elongate element is secured to the rounded tip. A vibrator is secured to the proximal extremity of the flexible elongate element for imparting vibratory motion to the flexible elongate element to cause vibratory impact motion of the rounded tip in a direction longitudinal of the axis of the flexible elongate element.
摘要翻译：柔性细长装置，其包括具有近端和远端的柔性细长管状构件。提供了具有近端和远端的柔性螺旋弹簧。螺旋弹簧的近端被固定到柔性细长管状构件的远端。圆形尖端固定到螺旋弹簧的远端。具有近端和远端的柔性细长元件设置在所述螺旋弹簧内并且延伸到螺旋弹簧的纵向。柔性细长元件的远端被固定到圆形尖端。振动器被固定到柔性细长元件的近端，用于向柔性细长元件施加振动运动，以引起圆形尖端在柔性细长元件的轴线方向上的振动冲击运动。

83. 发明授权

US5588964A Steerable catheter with adjustable bend location and/or radius and method 失效
标题翻译：具有可调弯曲位置和/或半径和方法的可导向导管
公开(公告)号：US5588964A
公开(公告)日：1996-12-31
申请号：US382622
申请日：1995-02-02
申请人： Mir A. Imran , Mark L. Pomeranz , Brian A. Glynn
发明人： Mir A. Imran , Mark L. Pomeranz , Brian A. Glynn
IPC分类号： A61B17/00 , A61B18/14 , A61M25/01 , A61M37/00
CPC分类号： A61M25/0144 , A61B18/1492 , A61M25/0136 , A61M25/0147 , A61M25/0158 , A61B2017/003 , A61B2017/00867 , A61B2018/00351 , A61B2018/00577 , A61B2018/0091 , A61B2018/00916 , A61B2018/00946 , A61B2018/1253 , A61B2018/1467
摘要： A steerable catheter comprising a flexible elongate tubular member having proximal and distal extremity. A handle is secured to the proximal extremity tubular member said a lumen extending therethrough. A mandrel is slidably mounted in the lumen and extends into the distal extremity. A mechanism extends through the tubular member for causing bending of the distal extremity with respect to the mandrel disposed therein.
摘要翻译：导管，其包括具有近端和远端的柔性细长管状构件。手柄固定到近端管状构件，所述近端管状构件表示延伸穿过其中的内腔。心轴可滑动地安装在内腔中并延伸到远端。机构延伸穿过管状构件，用于相对于设置在其中的心轴弯曲远侧末端。

84. 发明授权

US5578007A Endocardial mapping and ablation system utilizing a separately controlled ablation catheter and method 失效
标题翻译：使用单独控制的消融导管和方法的心内膜测绘和消融系统
公开(公告)号：US5578007A
公开(公告)日：1996-11-26
申请号：US439663
申请日：1995-05-11
申请人： Mir A. Imran
发明人： Mir A. Imran
IPC分类号： A61B17/00 , A61B1/00 , A61B17/22 , A61B18/00 , A61B18/14 , A61M25/00 , A61M25/01 , A61M37/00
CPC分类号： A61M25/0158 , A61B18/1492 , A61B18/1815 , A61B2017/00292 , A61B2017/003 , A61B2017/00867 , A61B2018/0016 , A61B2018/00196 , A61B2018/00214 , A61B2018/00267 , A61B2018/00357 , A61B2018/00505 , A61B2018/00839 , A61M25/0147 , C08L2201/12
摘要： Endocardial mapping and ablation system for introduction into a chamber of a heart formed by a wall and having a passage leading thereto. The system is comprised of a catheter probe having a distal extremity. A plurality of electrodes are carried by the distal extremity for mapping the wall of the chamber. An ablation catheter is provided having a distal extremity. The ablation catheter has control means whereby the distal extremity can be bent separately of movement of the catheter probe to come into close proximity to the wall of the heart. The distal extremity of the ablation catheter is provided with capabilities for ablating a portion of the wall of the heart to eliminate an arrythmia in the heart.
摘要翻译：用于引入由壁形成并具有通向其的通道的心室的心内膜定位和消融系统。该系统由具有远端的导管探针构成。多个电极由远端承载以映射室的壁。提供具有远端末端的消融导管。消融导管具有控制装置，由此远端可以与导管探针的运动分开地弯曲成靠近心脏壁。消融导管的远端具有用于烧蚀心脏壁的一部分以消除心脏中的心律不齐的能力。

85. 发明授权

US5540722A Switch apparatus and method for switching between multiple electrodes for diagnostic and therapeutic procedures 失效
标题翻译：用于在多个电极之间切换用于诊断和治疗程序的开关装置和方法
公开(公告)号：US5540722A
公开(公告)日：1996-07-30
申请号：US243229
申请日：1994-05-16
申请人： Christopher R. Clare , Mir A. Imran
发明人： Christopher R. Clare , Mir A. Imran
IPC分类号： A61B18/12 , A61B18/14 , A61B18/16 , A61N1/00 , A61N1/39 , A61N1/40
CPC分类号： A61B18/1206 , A61B18/12 , A61B18/14 , A61N1/39 , A61N1/40 , A61B18/16 , A61B2018/00178 , A61B2018/0066
摘要： A switch apparatus for performing diagnostic and/or therapeutic procedures on a patient by the use of first and second electrodes adapted to be placed on the patient and by the use of a defibrillator unit and another medical device utilizing radiofrequency energy from a radiofrequency generator unit comprising a multi-function adapter unit adapted to be coupled to the first and second electrodes and adapted to be coupled to the defibrillator unit and to the electrosurgery unit for switching between the defibrillation unit and another medical device to permit performing the diagnostic and therapeutic procedures on the patient utilizing the same first and second electrodes.
摘要翻译：一种开关装置，用于通过使用适于放置在患者身上的第一和第二电极以及使用除颤器单元和利用来自射频发生器单元的射频能量的另一医疗装置对患者执行诊断和/或治疗程序，所述射频能量包括多功能适配器单元，其适于联接到所述第一和第二电极并且适于耦合到所述除颤器单元和所述电外科单元，用于在所述除颤单元与另一医疗设备之间切换以允许在所述除颤器单元和所述电外科单元上执行所述诊断和治疗程序患者利用相同的第一和第二电极。

86. 发明授权

US5456254A Flexible strip assembly having insulating layer with conductive pads exposed through insulating layer and device utilizing the same 失效
标题翻译：具有通过绝缘层暴露的导电焊盘的绝缘层的柔性带组件和利用其的装置
公开(公告)号：US5456254A
公开(公告)日：1995-10-10
申请号：US223111
申请日：1994-04-05
申请人： Susan M. Pietroski , Mark S. Varner , Mir A. Imran
发明人： Susan M. Pietroski , Mark S. Varner , Mir A. Imran
IPC分类号： A61B5/042 , A61B17/00 , A61B18/14 , A61N1/05 , A61N1/36 , A61B5/04 , A61N1/04
CPC分类号： A61B5/6858 , A61B18/1492 , A61B5/0422 , A61N1/056 , A61B18/1402 , A61B2017/00292 , A61B2017/22038 , A61B2018/00083 , A61B2018/00107 , A61B2018/0016 , A61B2018/00214 , A61B2018/00267 , A61B2018/00357 , A61B2018/00577 , A61B2018/00839 , A61B2018/0091 , A61B2018/124 , A61B2018/1253 , A61B2018/126 , A61B2018/1435 , A61B2562/0209 , A61B2562/043 , A61N1/3605
摘要： A flexible elongate strip assembly for use in a medical device and including at least one longitudinally-extending layer of an insulating material having substantially planar spaced-apart parallel outer and inner surfaces. A plurality of pads formed from a conductive material are attached to the inner surface of the layer in longitudinally spaced-apart positions. The layer is provided with a plurality of openings extending between the outer and inner surfaces in spaced-apart positions so as to expose through the outer surface at least a portion of each pad. A plurality of spaced-apart generally parallel traces are attached to the inner surface and extend longitudinally of the layer from the pads. The exposed portion of each pad can serve as a conductive surface of an electrode.
摘要翻译：一种柔性细长条组合件，用于医疗装置，并且包括至少一个绝缘材料的纵向延伸层，所述绝缘材料具有基本平坦的间隔开的平行外表面和内表面。由导电材料形成的多个焊盘在纵向间隔开的位置附接到该层的内表面。该层设置有多个开口，其在间隔开的位置在外表面和内表面之间延伸，以便通过外表面暴露每个垫的至少一部分。多个间隔开的大致平行的迹线附着到内表面并且从该焊盘的该层的纵向延伸。每个焊盘的暴露部分可以用作电极的导电表面。

87. 发明授权

US5423771A Flexible elongate device having a distal extremity of adjustable stiffness and method 失效
标题翻译：柔性细长装置具有可调刚度和方法的远端
公开(公告)号：US5423771A
公开(公告)日：1995-06-13
申请号：US147005
申请日：1993-11-02
申请人： Mir A. Imran
发明人： Mir A. Imran
IPC分类号： A61M25/00 , A61M25/01 , A61M29/00 , A61M37/00
CPC分类号： A61M25/0158 , A61M25/0054 , C08L2201/12
摘要： A device comprising a flexible elongate member having proximal and distal extremities. A flexible coil spring is provided having proximal and distal extremities. The proximal extremity of the coil spring is secured to the distal extremity of the flexible elongate member. A shape-memory alloy element is disposed within and extends substantially longitudinally of the coil spring. The shape-memory alloy element has a memory which makes it attempt to assume a straight shape when an electrical current is passed through and heats the same. The shape-memory alloy element also has a stiffness which increases with the temperature of the element. An electrical current supply is provided for supplying an electrical current to the shape-memory alloy element for changing the stiffness of the shape-memory alloy element to thereby stiffen the distal extremity of the flexible elongate member.
摘要翻译：一种包括具有近端和远端的柔性细长构件的装置。提供了具有近端和远端的柔性螺旋弹簧。螺旋弹簧的近端被固定到柔性细长构件的远端。形状记忆合金元件设置在螺旋弹簧的大致纵向上并且基本上沿其延伸。形状记忆合金元件具有当电流通过并使其加热时尝试呈现直线形状的记忆。形状记忆合金元件还具有随着元件的温度而增加的刚度。提供电流源用于向形状记忆合金元件提供电流，以改变形状记忆合金元件的刚度，从而加强柔性细长构件的远端。

88. 发明授权

US5357979A Flexible elongate device having a distal extremity with current controlled adjustable stiffness and adjustable bend location and method 失效
标题翻译：柔性细长装置具有远端，具有电流控制的可调刚度和可调节的弯曲位置和方法
公开(公告)号：US5357979A
公开(公告)日：1994-10-25
申请号：US116666
申请日：1993-09-03
申请人： Mir A. Imran
发明人： Mir A. Imran
IPC分类号： A61M25/00 , A61M25/01 , A61B5/00
CPC分类号： A61M25/0158 , A61M25/0054 , C08L2201/12
摘要： Flexible elongate device comprising a flexible elongate member having proximal and distal extremities, a shape-memory element is disposed in the flexible elongate member and is capable of assuming martensitic and austenitic states and has first and second portions. A layer of conductive material is formed on at least one of said portions. The layer has a conductivity greater than that of the shape-memory element. Electrical current is supplied to the shape-memory element. The conductive layer serves to conduct current and shunts current flow around that portion of the shape-memory element having the layer of conductive material thereon.
摘要翻译：柔性细长装置包括具有近端和远端的柔性细长构件，形状记忆元件设置在柔性细长构件中并且能够呈现马氏体和奥氏体状态并具有第一和第二部分。在至少一个所述部分上形成导电材料层。该层的导电率大于形状记忆元件的导电率。电流被提供给形状记忆元件。导电层用于传导电流并且在其上具有导电材料层的形状记忆元件的该部分周围流过电流。

89. 发明授权

US5342295A Catheter assembly, catheter and multi-port introducer for use therewith 失效
标题翻译：导管组件，导管和多端口导引器
公开(公告)号：US5342295A
公开(公告)日：1994-08-30
申请号：US126314
申请日：1993-09-24
申请人： Mir A. Imran
发明人： Mir A. Imran
IPC分类号： A61B5/042 , A61B17/00 , A61B18/14 , A61M25/00 , A61M25/01 , A61M3/00 , A61M5/00 , A61M5/178 , A61M31/00
CPC分类号： A61B5/6859 , A61B18/1492 , A61B5/0422 , A61M25/0026 , A61B2017/00053 , A61B2017/00243 , A61B2018/00148 , A61B2018/00267 , A61B2018/00916 , A61B2018/1435 , A61B2562/0209 , A61B2562/043 , A61M25/01
摘要： Catheter assembly for use in performing medical procedures in the body of a patient having a vessel therein comprising a multi-port introducer adapted to be inserted into a vessel of the patient and a plurality of catheters disposed in the multi-port introducer and adapted to be disposed in the vessel of the patient.
摘要翻译：用于在其中具有容器的患者的身体中进行医疗程序的导管组件，其包括适于插入患者血管的多端口导引器和设置在多端口引导器中的多个导管，放置在患者的血管中。

90. 发明授权

US5331959A Low impedance, low durometer, dry conforming contact member 失效
标题翻译：低阻抗，低硬度，干燥的接触构件
公开(公告)号：US5331959A
公开(公告)日：1994-07-26
申请号：US745863
申请日：1991-08-16
申请人： Mir A. Imran
发明人： Mir A. Imran
IPC分类号： A61B5/0408 , A61N1/04 , A61B5/04 , A61N1/05
CPC分类号： A61N1/0456 , A61B5/0408 , A61N1/0492
摘要： Contact member comprised of a mass of nonconductive material having a low durometer and conductive elements dispersed in the mass of material in sufficient quantity to establish contact between the elements to provide a resistivity in the range of 10 to 100 ohm-cm.
摘要翻译：接触构件由具有低硬度的大量非导电材料和分散在材料块中的导电元素组成，其质量足以建立元件之间的接触，以提供10至100欧姆 - 厘米范围内的电阻率。

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