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81. 发明申请

US20100209439A1 Anti-Prominin-1 Antibody having ADCC Activity or CDC Activity 失效
标题翻译：具有ADCC活性或CDC活性的抗Prominin-1抗体
公开(公告)号：US20100209439A1
公开(公告)日：2010-08-19
申请号：US12666418
申请日：2008-06-25
申请人： Kenji Yoshida
发明人： Kenji Yoshida
IPC分类号： C07K16/30 , A61K39/395
CPC分类号： C07K16/2896 , C07K2317/24 , C07K2317/56 , C07K2317/565 , C07K2317/72
摘要： An objective of the present invention is to provide antibodies that bind to Prominin-1 and have ADCC activity and/or CDC activity, and pharmaceutical compositions containing those antibodies as an active ingredient.To achieve a solution to the above-mentioned objective, the present inventors produced recombinant antibodies by cloning a nucleotide sequence of the AC133 antibody variable region, discovered that the ADCC/CDC-inducing effect which does not exist in the original AC133 antibody is imparted to the recombinant antibodies, and thereby completed the present invention. In the human chimeric antibody/human effector cell combination, the chimeric antibody whose constant region sequence had been converted to human IgG1/κ was found to induce strong ADCC. Furthermore, the present inventors produced humanized antibodies prepared by grafting the AC133 antibody CDRs to a human antibody sequence, and further produced humanized antibodies having binding activities equivalent to the activity of the chimeric antibody by introducing amino acid substitutions into the humanized L chain sequence. The present invention provides unlabeled AC133 human chimeric antibodies and humanized antibodies having antitumor effects.
摘要翻译：本发明的目的是提供结合Prominin-1并具有ADCC活性和/或CDC活性的抗体，以及含有这些抗体作为活性成分的药物组合物。为了实现上述目的的解决方案，本发明人通过克隆AC133抗体可变区的核苷酸序列产生重组抗体，发现赋予原始AC133抗体中不存在的ADCC / CDC诱导作用赋予重组抗体，从而完成了本发明。在人嵌合抗体/人效应细胞组合中，其恒定区序列已转化为人IgG1 / 被发现诱导强ADCC。此外，本发明人通过将AC133抗体CDR移植到人抗体序列而制备人源化抗体，并通过将人源化L链序列引入氨基酸取代而进一步制备具有与嵌合抗体活性相当的结合活性的人源化抗体。本发明提供了未标记的AC133人嵌合抗体和具有抗肿瘤作用的人源化抗体。

82. 发明申请

US20100121737A1 PERSONAL IDENTIFICATION NUMBER CODE INPUT METHOD USING DOT PATTERN, PERSONAL IDENTIFICATION NUMBER CODE INPUT METHOD, AND INTERNET SHOPPING SETTLEMENT SYSTEM 审中-公开
标题翻译：个人识别代码输入法使用点图案，个人识别码代码输入法和互联网购物结算系统
公开(公告)号：US20100121737A1
公开(公告)日：2010-05-13
申请号：US12523015
申请日：2008-01-15
申请人： Kenji Yoshida
发明人： Kenji Yoshida
IPC分类号： G06Q20/00 , G06K7/00 , G06Q30/00
CPC分类号： G07F19/205 , G06F3/0418 , G06F3/04886 , G06F21/31 , G06F21/313 , G06F21/34 , G06F21/36 , G06F21/83 , G06Q20/40 , G06Q30/0601 , G07C9/00039 , G07F7/10 , G07F7/1033 , G07F19/20
摘要： A PIN code input method which is low cost and operated easily and ensures high security is presented. The PIN code input method specifies and inputs a plurality of identifiable symbol icons printed or displayed on a medium surface in a predetermined order, based on which order the PIN code is authenticated. The PIN code input method uses a dot pattern signifying a coordinate value or/and a code value formed on the medium surface where the symbol icons are printed or the visual surface where the symbol icons are displayed. The dot pattern is read by a scanner and converted into the PIN code according to the coordinate value or/and code value. The PIN code is authenticated based on the order of the PIN code read. Upon reading the dot pattern by the scanner, the orientation of the scanner relative to a vertical axis perpendicular to the medium surface or the visual surface is input together with the coordinate value or/and code value signified by the dot pattern as the PIN code.
摘要翻译：提供了低成本，易于操作并确保高安全性的PIN码输入方法。 PIN码输入法基于PIN码被认证的顺序，以预定顺序指定和输入在介质表面上打印或显示的多个可识别符号图标。 PIN码输入法使用表示在打印符号图标的介质表面上形成的坐标值或/和代码值的点图案或者显示符号图标的视觉表面。点阵图由扫描仪读取，并根据坐标值或/和代码值转换为PIN码。 PIN码根据读取的PIN码的顺序进行认证。在通过扫描仪读取点阵图形时，扫描仪相对于垂直于中间表面或视觉表面的垂直轴的取向与由点阵图形表示的坐标值或/和代码值一起输入作为PIN码。

83. 发明申请

US20100046110A1 INFORMATION PROCESSING APPARATUS AND CONTROL METHOD THEREOF 有权
标题翻译：信息处理装置及其控制方法
公开(公告)号：US20100046110A1
公开(公告)日：2010-02-25
申请号：US12546606
申请日：2009-08-24
申请人： Kenji Yoshida
发明人： Kenji Yoshida
IPC分类号： G11B19/02
CPC分类号： G11B19/02
摘要： Disclosed is an information processing apparatus. The information processing apparatus includes a first hard disk drive, a conversion circuit and a signal control circuit. The conversion circuit is connected with the first hard disk drive to determine whether a second hard disk drive corresponding to a slave exists when the first hard disk drive serves as a master, and the determine whether a first control signal has a first logic level in a first predetermined time.
摘要翻译：公开了一种信息处理装置。信息处理装置包括第一硬盘驱动器，转换电路和信号控制电路。转换电路与第一硬盘驱动器连接，以确定当第一硬盘驱动器用作主机时是否存在对应于从设备的第二硬盘驱动器，并且确定第一控制信号是否具有第一逻辑电平第一预定时间。

84. 发明授权

US07667332B2 Method for generating pattern, method for manufacturing semiconductor device, semiconductor device, and computer program product 失效
标题翻译：产生图案的方法，制造半导体器件的方法，半导体器件和计算机程序产品
公开(公告)号：US07667332B2
公开(公告)日：2010-02-23
申请号：US11265231
申请日：2005-11-03
申请人： Masaaki Hatano , Motoya Okazaki , Junichi Wada , Takeshi Nishioka , Hisashi Kaneko , Takeshi Fujimaki , Kazuyuki Higashi , Kenji Yoshida , Noriaki Matsunaga
发明人： Masaaki Hatano , Motoya Okazaki , Junichi Wada , Takeshi Nishioka , Hisashi Kaneko , Takeshi Fujimaki , Kazuyuki Higashi , Kenji Yoshida , Noriaki Matsunaga
IPC分类号： H01L23/52 , H01L23/48 , H01L29/40
CPC分类号： G06F17/5068
摘要： A method for generating a pattern includes reading out an interconnect layout and a hole layout, the interconnect layout prescribing interconnect patterns, the hole layout prescribing hole patterns configured to connect to the interconnect patterns; extracting one of the hole patterns to be connected within the same interconnect layer level to one of the interconnect patterns in a pattern processing area; extracting a first processing area including the extracted hole pattern; calculating a first pattern density of the interconnect patterns included in the first processing area; and generating first additional patterns in the first processing area based on the first pattern density.
摘要翻译：一种用于产生图案的方法包括：读出互连布局和孔布局;布置规定互连图案的布局布局;布置配置为连接到互连图案的孔图案的孔布局; 在图案处理区域中将在相同互连层级中连接的孔图案中的一个提取到所述互连图案之一; 提取包括所提取的孔图案的第一处理区域; 计算包括在第一处理区域中的互连图案的第一图案密度; 以及基于所述第一图案密度在所述第一处理区域中生成第一附加图案。

85. 发明申请

US20100039053A1 TORQUE CONTROL DEVICE AND METHOD FOR CONTROLLING THE SAME 有权
标题翻译：扭矩控制装置及其控制方法
公开(公告)号：US20100039053A1
公开(公告)日：2010-02-18
申请号：US12605373
申请日：2009-10-26
申请人： Ryuta MATSUTANI , Kenji Yoshida , Shigeru Sakurai
发明人： Ryuta MATSUTANI , Kenji Yoshida , Shigeru Sakurai
IPC分类号： H02P5/46
CPC分类号： B25B21/00 , B23P19/066 , B25B23/14
摘要： A torque control device controlling torque of first and second mechanical units connected coaxially to each other through connecting members includes a controller generating first and second references from a command from a host system, first and second motors respectively driving the first and second mechanical units, first and second motor control units respectively controlling the first and second motors on the basis of the first and second references. The first and second references synchronously accelerate the first and second motors to first rotational speed, then increase rotational speed of the second motor according to a speed profile to produce torsional torque in the connecting members, decelerate the second motor to the first rotational speed after the torsional torque reaches a predetermined value, and synchronously decelerate and stop the first and second motors after a predetermined time period elapses.
摘要翻译：控制通过连接构件彼此同轴连接的第一和第二机械单元的扭矩的转矩控制装置包括控制器，其根据来自主机系统的命令产生第一和第二参考，第一和第二电动机分别驱动第一和第二机械单元，第一以及第二电动机控制单元，其基于第一和第二参考分别控制第一和第二电动机。第一和第二参考同步地将第一和第二电动机加速到第一转速，然后根据速度曲线提高第二电动机的转速，以在连接构件中产生扭转扭矩，在第二电动机之后将第二电动机减速到第一转速扭转扭矩达到预定值，并且在经过预定时间段之后同步地减速和停止第一和第二电动机。

86. 发明申请

US20090276685A1 DATA DECODING APPARATUS, MAGNETIC DISK APPARATUS, AND DATA DECODING METHOD 审中-公开
标题翻译：数据解码设备，磁盘设备和数据解码方法
公开(公告)号：US20090276685A1
公开(公告)日：2009-11-05
申请号：US12345578
申请日：2008-12-29
申请人： Kenji Yoshida
发明人： Kenji Yoshida
IPC分类号： H03M13/05 , G06F11/07
CPC分类号： G11B20/1833 , G11B2020/185 , G11B2220/2516
摘要： A data decoding apparatus has: a check matrix including a submatrix which indicates a parity restriction and used for LDPC decoding; a first decoding module configured to decode data by using the submatrix so that the parity restriction is satisfied; and a second decoding module configured to LDPC-decode the decoded data by using the check matrix.
摘要翻译：数据解码装置具有：包括表示奇偶限制并用于LDPC解码的子矩阵的校验矩阵; 第一解码模块，被配置为通过使用所述子矩阵来解码数据，使得满足所述奇偶限制; 以及第二解码模块，被配置为通过使用所述校验矩阵对所解码的数据进行LDPC解码。

87. 发明授权

US07573659B2 Optical element holding apparatus and exposure apparatus 失效
标题翻译：光学元件保持装置和曝光装置
公开(公告)号：US07573659B2
公开(公告)日：2009-08-11
申请号：US11925373
申请日：2007-10-26
申请人： Ichiro Onuki , Kenichi Kobayashi , Kenji Yoshida , Jun Ota
发明人： Ichiro Onuki , Kenichi Kobayashi , Kenji Yoshida , Jun Ota
IPC分类号： G02B7/02
CPC分类号： G02B27/62 , G02B7/023 , G03F7/70825 , G03F7/7085
摘要： A holding apparatus for holding an optical element includes a measuring part configured to measure a coordinate of the optical element, and a driving part configured to move the optical element based on the coordinate measured by the measuring part, wherein the measuring part includes a first sensor configured to detect a displacement amount of a part of the optical element, and a second sensor configured to detect that a part of the optical element is located at a predetermined position.
摘要翻译：用于保持光学元件的保持装置包括被配置为测量光学元件的坐标的测量部件和被配置为基于由测量部件测量的坐标来移动光学元件的驱动部件，其中测量部件包括第一传感器被配置为检测所述光学元件的一部分的位移量;以及第二传感器，被配置为检测所述光学元件的一部分位于预定位置。

88. 发明申请

US20090153999A1 HARD DISK, CONTROL UNIT FOR A DISK DEVICE, AND METHOD FOR CONTROLLING A DISK DEVICE 有权
标题翻译：用于盘装置的硬盘，控制单元以及用于控制盘装置的方法
公开(公告)号：US20090153999A1
公开(公告)日：2009-06-18
申请号：US12165459
申请日：2008-06-30
申请人： Kenji Yoshida , Yuuichi Abe
发明人： Kenji Yoshida , Yuuichi Abe
IPC分类号： G11B15/18 , G11B5/82 , G11B27/00
CPC分类号： G11B20/1883 , G11B2020/1281 , G11B2020/1893 , G11B2220/20 , G11B2220/2516
摘要： A hard disk includes: a plurality of servo areas which are elongated radially from a center of the hard disk to an outward thereof over tracks thereof; and a plurality of data areas which are respectively provided between the plurality of servo areas; wherein alternative operation is conducted per servo sector containing one of the plurality of servo areas and a data area provided subsequent to the one of the plurality of servo areas and having a defect created therein when a user sector containing at least a portion of the data area and functioning as an access unit has the defect therein.
摘要翻译：硬盘包括：多个伺服区，其从硬盘的中心径向延伸到其轨道的外侧; 以及分别设置在所述多个伺服区域之间的多个数据区域; 其中，对于包含所述多个伺服区域中的一个的每个伺服扇区和在所述多个伺服区域中的所述伺服区域之后提供的数据区域进行替换操作，并且当包含所述数据区域的至少一部分的用户扇区并且作为存取单元起作用。

89. 发明申请

US20090094034A1 VOICE INFORMATION RECORDING APPARATUS 有权
标题翻译：语音信息记录装置
公开(公告)号：US20090094034A1
公开(公告)日：2009-04-09
申请号：US11914917
申请日：2006-05-19
申请人： Kenji Yoshida
发明人： Kenji Yoshida
IPC分类号： G10L13/02 , G06K7/10
CPC分类号： G11B27/034 , G10L13/043 , G10L15/00 , G11B20/00 , G11B27/00 , G11B27/105 , G11B33/10 , G11B2020/10546 , G11B2220/17 , H04N1/00403
摘要： A link table is generated, voice information is associated by dot patterns, and then, voice information associated with the dot pattern is reproduced from a speaker when the dot pattern is read by means of a scanner. In this manner, the dot pattern is printed on a surface of a material such as a picture book or a card, making it possible to play back voice information corresponding to a pattern or a story of a picture book and to play back voice information corresponding to a character described on the card. In addition, by means of a link table, new voice information can be associated with, dissociated from, or changed to, a new dot pattern.
摘要翻译：生成链接表，通过点图案关联语音信息，然后当通过扫描仪读取点图案时，从扬声器再现与点图案相关联的语音信息。以这种方式，将点图案印刷在诸如图画书或卡片的材料的表面上，使得可以播放与图画书的图案或故事相对应的语音信息，并且播放对应的语音信息到卡上描述的一个角色。另外，通过链接表，新的语音信息可以与新的点图案相关联，分离或改变为新的点图案。

90. 发明申请

US20090086031A1 Communication system, communication method, computer-readable medium and image shooting device 有权
标题翻译：通信系统，通信方式，计算机可读介质和图像拍摄设备
公开(公告)号：US20090086031A1
公开(公告)日：2009-04-02
申请号：US12219680
申请日：2008-07-25
申请人： Satoru Wakabayashi , Kenji Yoshida
发明人： Satoru Wakabayashi , Kenji Yoshida
IPC分类号： H04N5/225 , H04B7/24
CPC分类号： H04N5/23203 , H04N1/00347 , H04N2101/00 , H04N2201/0015 , H04N2201/0041 , H04N2201/0044 , H04N2201/0055 , H04N2201/0084
摘要： A communication system includes a first and a second communication devices, and the first and the second communication devices includes a first and a second transmission units that are disposed respectively on bodies of the communication devices and wirelessly transmits predetermined information to each other. The first communication device further includes a first reception unit that is disposed in a position where the first reception unit is capable of communicating with the second transmission unit and receives second information that has been transmitted from the second transmission unit, and a first control unit that controls the first communication device such that, when communication becomes possible between the first reception unit and the second transmission unit, the first reception unit receives the second information, and such that, when communication becomes possible between the first transmission unit and the second reception unit, the first transmission unit transmits first information.
摘要翻译：通信系统包括第一和第二通信设备，并且第一和第二通信设备包括分别设置在通信设备的主体上并彼此无线地发送预定信息的第一和第二传输单元。第一通信装置还包括：第一接收单元，其设置在第一接收单元能够与第二发送单元通信并接收从第二发送单元发送的第二信息的位置;以及第一控制单元，控制第一通信装置，使得当第一接收单元和第二发送单元之间进行通信时，第一接收单元接收第二信息，并且当第一发送单元和第二接收单元之间进行通信时，第一发送单元发送第一信息。

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