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81. 发明授权

US08406495B2 MR segmentation using transmission data in hybrid nuclear/MR imaging 失效
标题翻译：在混合核/ MR成像中使用传输数据进行MR分割
公开(公告)号：US08406495B2
公开(公告)日：2013-03-26
申请号：US13062222
申请日：2009-09-09
申请人： Daniel Gagnon , Zhiqiang Hu
发明人： Daniel Gagnon , Zhiqiang Hu
IPC分类号： G06K9/00
CPC分类号： G01R33/481 , G01R33/5608 , G06T7/11 , G06T2207/10088 , G06T2207/10104 , G06T2207/30004
摘要： When correcting attenuation in a nuclear image (e.g., PET or SPECT), an MR-based attenuation correction (AC) map (16) is generated using MR image data (14) of a subject (60). The subject (60) is then placed in a nuclear imaging device with a radioactive point or line source (18, 18′) from which transmission data is measured as the patient is imaged. In order to resolve ambiguity between air voxels and bone voxels in the MR-based AC map (16), estimated transmission data (24) is generated from the AC map and compared to the measured transmission data (22) from the point or line source. An error is iteratively calculated for the estimated and measured transmission data, and attenuation values of the AC map (16) are refined to minimize the error. The refined AC map (32) is used to correct attenuation in collected nuclear data (41) which is reconstructed into an attenuation corrected image (99) of the patient.
摘要翻译：当校正核图像（例如PET或SPECT）中的衰减时，使用对象（60）的MR图像数据（14）来生成基于MR的衰减校正（AC）图（16）。然后将受试者（60）放置在具有放射性点或线源（18,18'）的核成像装置中，当患者被成像时从该源成像传播数据。为了解决基于MR的AC映射（16）中的空气体素和骨骼体素之间的模糊性，从AC映射产生估计的传输数据（24），并与来自点或线源的测量的传输数据（22）进行比较。对于估计和测量的传输数据迭代地计算误差，并且AC映射（16）的衰减值被改进以使误差最小化。精细AC图（32）用于校正收集的核数据（41）中的衰减，其被重建成患者的衰减校正图像（99）。

82. 发明授权

US08269628B2 Refrigeration case motion detector 失效
标题翻译：制冷箱运动检测器
公开(公告)号：US08269628B2
公开(公告)日：2012-09-18
申请号：US12646586
申请日：2009-12-23
申请人： Daniel Gagnon , Paul Lukas , Robert Baker
发明人： Daniel Gagnon , Paul Lukas , Robert Baker
IPC分类号： G08B13/18 , G08B19/00
CPC分类号： H05B37/0227 , F21V23/0442 , Y02B20/44
摘要： A triple-sensor motion detector is provided for illuminating the approach to a display case or other object. The triple-sensor motion detector provides a field of detection that spans the front width of the case, yet does not include the areas along the sides of the case. The detector reduces inadvertent triggering of the illumination by persons approaching the side of the case or approaching another case on the other side of an aisle.
摘要翻译：提供了一种三重传感器运动检测器，用于照明到显示器壳体或其他物体的方法。三重传感器运动检测器提供跨越壳体前部宽度的检测领域，但不包括沿壳体侧面的区域。检测器减少人员接近壳体侧面或靠近通道另一侧的人的照明的无意触发。

83. 发明申请

US20120089015A1 REGIONAL RECONSTRUCTION AND QUANTITATIVE ASSESSMENT IN LIST MODE PET IMAGING 有权
标题翻译：列表模式PET成像中的区域重建和定量评估
公开(公告)号：US20120089015A1
公开(公告)日：2012-04-12
申请号：US13145115
申请日：2009-12-23
申请人： Daniel Gagnon , Piotr J. Maniawski
发明人： Daniel Gagnon , Piotr J. Maniawski
IPC分类号： A61B6/03 , A61B6/00 , G06K9/00
CPC分类号： G06T11/006 , A61B6/037
摘要： A method for reconstructing list mode data comprises: reconstructing all list mode data of a list mode data set (30, 160) to generate a first reconstructed image (32, 62); selecting a sub-set of the list mode data set; and reconstructing the sub-set of the list mode data set to generate an enhanced reconstructed image (84, 86). An image generation system comprises: a reconstruction module (24) configured to perform a standard reconstruction of a list mode data set to generate a standard reconstructed image (32, 62); and a re-reconstruction module (24, 70, 80, 82, 150, 152, 154) configured to perform a reconstruction other than the standard reconstruction of at least a portion of the list mode data set to generate an enhanced reconstructed image (84, 86).
摘要翻译：重建列表模式数据的方法包括：重建列表模式数据集（30,160）的所有列表模式数据，以生成第一重建图像（32,62）; 选择列表模式数据集的子集; 以及重建列表模式数据集的子集以生成增强的重建图像（84,86）。一种图像生成系统包括：重建模块（24），被配置为执行列表模式数据集的标准重建以生成标准重建图像（32,62）; 以及重建重建模块（24,70,80,82,150,152,154），其被配置为执行不同于所述列表模式数据集的至少一部分的标准重建的生成增强重建图像（84 ，86）。

84. 发明申请

US20110064295A1 GEOMETRICAL TRANSFORMATIONS PRESERVING LIST-MODE FORMAT 有权
标题翻译：几何变换保存列表模式格式
公开(公告)号：US20110064295A1
公开(公告)日：2011-03-17
申请号：US12991719
申请日：2009-05-13
申请人： Daniel Gagnon , Patrick Olivier , Parmeshwar Kishore Khurd
发明人： Daniel Gagnon , Patrick Olivier , Parmeshwar Kishore Khurd
IPC分类号： G06K9/00
CPC分类号： G01T1/1648 , A61B6/037 , G06T11/005
摘要： A diagnostic imaging device includes detector elements (16) for detecting γ- rays indicative of nuclear decay events. The detected γ-rays are used to produce lines of response (LORs) (46), which are time stamped (20) and stored in list mode. The LORs are reconstructed (34) into an image. An image analysis processor (38) analyzes the image for motion artifacts and iteratively adjusts an event transform processor (30) to transform selected LORs to minimize the motion artifacts. If the transformed LOR (50) does not correspond with a pair of detector elements (16), closest detector elements (52, 54) are determined. Candidate LORs (62) are created between the closest and neighboring detector elements. An event location (40) on an LOR (46) is determined from the time-of-flight (TOF) information and then transformed (47) to generate a transformed event location (48). The candidate LOR (62) which most nearly intersects the transformed event location (40) and the appropriately updated TOF information is selected for use in image reconstruction.
摘要翻译：诊断成像装置包括用于检测指示核衰变事件的γ射线的检测器元件（16）。检测到的γ射线用于产生响应线（LOR）（46），它们是时间戳的（20）并以列表模式存储。 LOR被重构（34）成为图像。图像分析处理器（38）分析运动伪像的图像，并迭代地调整事件变换处理器（30）以变换所选择的LOR以最小化运动伪影。如果变换的LOR（50）不对应于一对检测器元件（16），则确定最近的检测器元件（52,54）。在最近和相邻的检测器元件之间创建候选LOR（62）。根据飞行时间（TOF）信息确定LOR（46）上的事件位置（40），然后变换（47）以生成转换的事件位置（48）。选择与变换的事件位置（40）最接近相交的候选LOR（62）和适当更新的TOF信息用于图像重建。

85. 发明申请

US20110024636A1 MODULAR MULTI-GEOMETRY PET SYSTEM 有权
标题翻译：模块化多元几何PET系统
公开(公告)号：US20110024636A1
公开(公告)日：2011-02-03
申请号：US12935302
申请日：2009-03-20
申请人： Daniel Gagnon , Douglas B. Mcknight
发明人： Daniel Gagnon , Douglas B. Mcknight
IPC分类号： G01T1/164 , G01T1/20
CPC分类号： G01T1/2985 , A61B6/037 , G01R33/481
摘要： When performing positron emission tomography (PET) scanning and image reconstruction, a primary PET system (10) with a primary PET detector array (12) is used to image a patient or subject, and a secondary PET detector array (14) is coupled to the system at specific input points to mitigate unnecessary duplication of system components. The primary system (10) provides PET data processing and reconstruction for the secondary array (14), in addition to the first array (12). An adjustable array (120) includes radially movable detectors (122) and stationary detectors (124) with different crystal resolutions. The movable detectors (122) are alternately positioned with the stationary detectors (124) at a first radius to form a large detector ring, or are positioned at a second, smaller radius without the stationary detectors (124) to form a small detector ring.
摘要翻译：当进行正电子发射断层扫描（PET）扫描和图像重建时，使用具有主要PET检测器阵列（12）的主要PET系统（10）对患者或受试者进行成像，并且将辅助PET检测器阵列（14）耦合到该系统在特定的输入点，以减轻不必要的系统组件重复。除了第一阵列（12）之外，主系统（10）还为次级阵列（14）提供PET数据处理和重建。可调节阵列（120）包括具有不同晶体分辨率的径向可移动探测器（122）和固定探测器（124）。移动检测器（122）与第一半径处的固定式检测器（124）交替定位以形成大的检测器环，或者定位在第二较小的半径处，而没有固定的检测器（124）以形成小的检测器环。

86. 发明申请

US20100135559A1 HYBRID MR/PET WITH CORRECTION FOR RADIATION ABSORPTION BY MR COIL 有权
标题翻译：混合MR / PET与MR线圈的辐射吸收校正
公开(公告)号：US20100135559A1
公开(公告)日：2010-06-03
申请号：US12598484
申请日：2008-04-17
申请人： Michael A. Morich , Gordon D. Demeester , Daniel Gagnon
发明人： Michael A. Morich , Gordon D. Demeester , Daniel Gagnon
IPC分类号： G06K9/62
CPC分类号： G01R33/481 , G01R33/4808 , G01T1/1603 , G01T1/1647
摘要： An imaging method comprises: acquiring magnetic resonance data of a subject using a magnetic resonance component (30, 30′) disposed with the subject; acquiring nuclear imaging data of the subject with the magnetic resonance component disposed with the subject; determining a position of the magnetic resonance component respective to a frame of reference of the nuclear imaging data; and reconstructing the nuclear imaging data (60) to generate a nuclear image (62) of at least a portion of the subject. The reconstructing includes adjusting at least one of the nuclear imaging data and the nuclear image based on a density map (46) of the magnetic resonance component and the determined position of the magnetic resonance component respective to the frame of reference of the nuclear imaging data to correct the nuclear image for radiation absorption by the magnetic resonance component.
摘要翻译：一种成像方法包括：使用与受检者一起设置的磁共振成分（30,30'）来获取对象的磁共振数据; 用设置在对象的磁共振成分获取对象的核成像数据; 确定所述磁共振成分相对于所述核成像数据的参考系的位置; 以及重构所述核成像数据（60）以产生所述受试者的至少一部分的核图像（62）。重建包括基于磁共振分量的密度图（46）和与核成像数据的参考系的相应的磁共振分量的确定的位置来调整核成像数据和核图像中的至少一个，通过磁共振成分校正核图像的辐射吸收。

87. 发明申请

US20090171183A1 PATIENT SCAN TIME OPTIMIZATION FOR PET/SPECT IMAGING 有权
标题翻译：患者扫描时间优化PET / SPECT成像
公开(公告)号：US20090171183A1
公开(公告)日：2009-07-02
申请号：US12088088
申请日：2006-09-15
申请人： Manoj Narayanan , Bart Jacob Bakker , Daniel Gagnon , Alexander Fischer , Lothar Spies
发明人： Manoj Narayanan , Bart Jacob Bakker , Daniel Gagnon , Alexander Fischer , Lothar Spies
IPC分类号： A61B5/05 , G06F19/00
CPC分类号： A61B6/00 , A61B6/037
摘要： An imaging system (10) comprises a data device (30), which controls radiation data acquisition from a subject positioned in an examination region (18) for an examination. A rebinning processor (40) bins the acquired data periodically into a histogram (42). A transform (70) transforms the histogram (42) into individual independent or uncorrelated components, each component including a signal content and a noise content. A stopping determining device (52) compares an aspect of at least one selected component to a predetermined threshold (TH) and, based on the comparison, terminates the data acquisition.
摘要翻译：成像系统（10）包括数据装置（30），其控制从位于检查区域（18）中的被摄体进行检查的辐射数据采集。重组处理器（40）将获取的数据周期性地存储到直方图（42）中。变换（70）将直方图（42）变换为独立的或不相关的分量，每个分量包括信号内容和噪声内容。停止确定装置（52）将至少一个所选择的组件的方面与预定阈值（TH）进行比较，并且基于该比较，终止数据采集。

88. 发明申请

US20080317194A1 Pet Imaging Using Anatomic List Mode Mask 审中-公开
标题翻译：宠物成像使用解剖列表模式掩码
公开(公告)号：US20080317194A1
公开(公告)日：2008-12-25
申请号：US12093152
申请日：2006-10-17
申请人： Daniel Gagnon , Wenli Wang , Zhiqiang Hu
发明人： Daniel Gagnon , Wenli Wang , Zhiqiang Hu
IPC分类号： A61B6/00
CPC分类号： G01T1/2985 , A61B6/037 , G01T1/1611 , G06T11/006 , G06T2211/424
摘要： A method and apparatus are provided for reconstructing list mode data acquired during a positron emission tomography scan of an object, the data including information indicative of a plurality of detected positron annihilation events. Detected events occurring in a region of interest are identified; the identified events are reconstructed using an iterative reconstruction technique which includes a ray tracing operation to generate volumetric data indicative of the region of interest, wherein the ray tracing operation traces only image matrix elements located in the region of interest; and a human readable image indicative of the volumetric data is generated. In another aspect an image mask and a projection mask are defined correlating to the region of interest; image matrix elements located in the region of interest are determined by applying the image mask; and detected events occurring in a region of interest are identified by applying the projection mask.
摘要翻译：提供了一种方法和装置，用于重建在对象的正电子发射断层摄影扫描期间获取的列表模式数据，该数据包括指示多个检测到的正电子湮灭事件的信息。确定在感兴趣区域发生的检测事件; 使用迭代重建技术来重建所识别的事件，所述迭代重建技术包括用于产生指示感兴趣区域的体积数据的光线跟踪操作，其中光线跟踪操作仅跟踪位于感兴趣区域中的图像矩阵元素; 并产生指示体积数据的人类可读取的图像。在另一方面，图像掩模和投影掩模被定义为与感兴趣区域相关; 通过应用图像掩模来确定位于感兴趣区域中的图像矩阵元素; 并且通过应用投影掩模来识别在感兴趣区域中发生的检测到的事件。

89. 发明申请

US20080285828A1 Method and System for Pet Image Reconstruction Using Portion of Event Data 有权
标题翻译：使用部分事件数据进行宠物图像重建的方法和系统
公开(公告)号：US20080285828A1
公开(公告)日：2008-11-20
申请号：US12091752
申请日：2006-10-30
申请人： Daniel Gagnon , Jeffrey A. Kolthammer
发明人： Daniel Gagnon , Jeffrey A. Kolthammer
IPC分类号： G06K9/00
CPC分类号： A61B6/037 , G06T11/006
摘要： A method and system for use in positron emission tomography, wherein a list-based reconstructor means (129) is configured to generate first portion volumetric data responsive to a first portion of a plurality of positron annihilation events detected during a positron emission tomography scan; generate a human-readable image indicative of the first portion volumetric data; use a list-based reconstruction technique to generate composite volumetric data responsive to the first portion volumetric data and a second portion of the plurality of positron annihilation events; and generate a composite human-readable image indicative of the composite volumetric data. In another aspect the reconstructor (129) is configured to selecting first or second portion event quantities responsive to one or more parameters including image definition requirements and processing time requirements.
摘要翻译：一种用于正电子发射断层摄影的方法和系统，其中基于列表的重建器装置（129）被配置为响应于在正电子发射断层摄影扫描期间检测到的多个正电子湮灭事件的第一部分而产生第一部分体积数据; 生成指示第一部分体积数据的人类可读图像; 使用基于列表的重建技术来响应于第一部分体积数据和多个正电子湮灭事件的第二部分来生成复合体积数据; 并生成指示复合体积数据的复合人类可读图像。在另一方面，重建器（129）被配置为响应于包括图像定义要求和处理时间要求的一个或多个参数来选择第一或第二部分事件量。

90. 发明申请

US20080253640A1 Method and System for Pet Image Reconstruction Using a Surogate Image 有权
标题翻译：使用Surogate图像进行宠物图像重建的方法和系统
公开(公告)号：US20080253640A1
公开(公告)日：2008-10-16
申请号：US12088090
申请日：2006-09-14
申请人： Daniel Gagnon , Wenli Wang , Zhiqiang Hu
发明人： Daniel Gagnon , Wenli Wang , Zhiqiang Hu
IPC分类号： G06K9/78
CPC分类号： G01T1/2985 , A61B6/037 , G01T1/1611 , G06T11/006
摘要： A method and system for use in positron emission tomography, wherein a first processor element (234) is configured to reconstruct a plurality of positron annihilation events detected during a positron emission tomography scan using a list-based reconstruction technique to generate first volumetric data. A second reconstructor (226) is configured to reconstruct the plurality of events using a second reconstruction technique to generate second volumetric data for determining an error correction (228), the error correction applied to the first volumetric data to generate corrected volumetric data for generating a human-readable image (234). In one embodiment a multiplicative error correction is performed on the plurality of events, the first processor element (234) reconstructing the corrected plurality of events; and the second volumetric data error correction comprises an additive error correction.
摘要翻译：一种用于正电子发射断层摄影的方法和系统，其中第一处理器元件（234）被配置为使用基于列表的重建技术来重建在正电子发射断层摄影扫描期间检测到的多个正电子湮灭事件以产生第一体积数据。第二重构器（226）被配置为使用第二重建技术来重建多个事件，以产生用于确定纠错（228）的第二体积数据，应用于第一体积数据的误差校正以产生校正的体积数据，以产生人类可读的图像（234）。在一个实施例中，对多个事件执行乘法误差校正，第一处理器元件（234）重建校正的多个事件; 并且第二体积数据误差校正包括加法误差校正。

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