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81. 发明申请

US20070016103A1 BODY FLUID SAMPLING DEVICE 有权
标题翻译：身体液体取样装置
公开(公告)号：US20070016103A1
公开(公告)日：2007-01-18
申请号：US11470368
申请日：2006-09-06
申请人： Irio Calasso , Patrick Griss , Emad Sarofim , Rainer Jaeggi , Uwe Kraemer , Dave Hasker , Volker Zimmer , Wilfried Schmid , Otto Fuerst , Hans List , Hans-Peter Haar , Theo Arnitz , Steven Roe
发明人： Irio Calasso , Patrick Griss , Emad Sarofim , Rainer Jaeggi , Uwe Kraemer , Dave Hasker , Volker Zimmer , Wilfried Schmid , Otto Fuerst , Hans List , Hans-Peter Haar , Theo Arnitz , Steven Roe
IPC分类号： A61B5/00
CPC分类号： A61B5/1411 , A61B5/14532 , A61B5/1486 , A61B5/150022 , A61B5/150068 , A61B5/150282 , A61B5/150358 , A61B5/150396 , A61B5/150419 , A61B5/150427 , A61B5/15045 , A61B5/150503 , A61B5/15151 , A61B5/15163
摘要： Body fluid sampling device comprising a skin-piercing element having a collection zone for receiving body fluid, and the device further comprising a fluid receiving means remote spaced apart from the collection zone so that body fluid in the collection zone will not contact the fluid receiving means initially. The collection zone takes up a very small volume of body fluid of about 10 to 500 nl in a very short time period of less than 0.5 seconds. The fluid receiving means may have a test zone for performing an analytical reaction. Fluid sample from the collection zone is automatically or manually transported to the fluid receiving means to contact the fluid with the test zone.
摘要翻译：体液取样装置包括具有用于接收体液的收集区的皮肤刺穿元件，并且该装置还包括与收集区间隔开的流体接收装置，使得收集区中的体液不会接触流体接收装置原来。收集区在小于0.5秒的非常短的时间段内占据非常小体积的体液约10至500nl。流体接收装置可以具有用于进行分析反应的测试区域。来自收集区的流体样品被自动或手动地输送到流体接收装置以使流体与测试区接触。

82. 发明申请

US20060240403A1 Tape magazine for a hand-held device 审中-公开
标题翻译：磁带杂志为手持设备
公开(公告)号：US20060240403A1
公开(公告)日：2006-10-26
申请号：US11376839
申请日：2006-03-16
申请人： Hans List , Hans-Peter Haar , Bernd Rosicke
发明人： Hans List , Hans-Peter Haar , Bernd Rosicke
IPC分类号： C12Q1/00
CPC分类号： A61B5/14532 , A61B10/0045 , A61B2562/0295 , B65H16/00 , B65H18/08 , G01N33/48764 , G01N35/00009 , Y10T436/2575
摘要： The present invention concerns a tape magazine especially for a hand-held device for analysing a body fluid with a test tape that can be unwound from a storage unit and wound onto a waste unit where the waste unit can be driven in order to wind forward the test tape. The invention provides that a lock which keeps the test tape under tension is integrated in the tape magazine at least on the storage unit. The present invention also concerns a hand-held device with such a tape magazine. The present invention also concerns a hand-held device with a mechanical drive for the test tape and a disposable hand-held device with polymer-based electronic components.
摘要翻译：本发明涉及一种专用于用于使用能够从存储单元展开并卷绕到废物单元上的测试带分析体液的手持式装置，其中可以驱动废物单元以向前推进测试胶带。本发明提供一种使测试带保持张紧的锁将至少在存储单元上整合在磁带盒中。本发明还涉及具有这种磁带盒的手持式装置。本发明还涉及具有用于测试带的机械驱动器的手持式装置和具有基于聚合物的电子部件的一次性手持式装置。

83. 发明授权

US06986754B2 Needleless hypodermic injection system, application device and medication cartridge therefor 失效
公开(公告)号：US06986754B2
公开(公告)日：2006-01-17
申请号：US10101400
申请日：2002-03-19
申请人： Hans-Peter Haar , George Bevan Kirby Meacham , Konrad Joseph Popp , Otto Bruntrup , Ulrich Josef Riemensperger , Guenter Franz Ihle , Bruno Robert Thös , Hans List , Dirk Bandau , Horst Engelhardt , Christian Gliewe
发明人： Hans-Peter Haar , George Bevan Kirby Meacham , Konrad Joseph Popp , Otto Bruntrup , Ulrich Josef Riemensperger , Guenter Franz Ihle , Bruno Robert Thös , Hans List , Dirk Bandau , Horst Engelhardt , Christian Gliewe
IPC分类号： A61M5/30
CPC分类号： A61M5/30 , A61M5/2046 , A61M5/2425 , A61M5/3129 , A61M5/5086 , A61M2005/2013 , A61M2005/3118 , A61M2005/312 , A61M2205/582 , A61M2205/583
摘要： A needleless hypodermic injection system for injecting a liquid medication, which system comprises a disposable cartridge which contains a medication and which includes a propellant and an igniter, and a reusable application device which comprises a pressure chamber for receiving the medication cartridge, actuation means including an ignition system and means for ensuring reliability and safety of the system. The reusable application device comprises: (a) a housing including a fist housing section and a second housing section which are adapted to be assembled together by a screwing operation, the first housing section comprising a front part having an injection outlet and a chamber adapted to receive a the cartridge contains the medication to be injected and also contains a propellant and an igniter, and (b) means for selectively activating said igniter of said cartridge when predetermined conditions are fulfilled.

84. 发明申请

US20050137471A1 Continuous glucose monitoring device 审中-公开
标题翻译：连续葡萄糖监测装置
公开(公告)号：US20050137471A1
公开(公告)日：2005-06-23
申请号：US10740056
申请日：2003-12-18
申请人： Hans-Peter Haar , Hans List , Felix Baader , Herbert Harttig , George Meacham
发明人： Hans-Peter Haar , Hans List , Felix Baader , Herbert Harttig , George Meacham
IPC分类号： A61B5/00 , G01N35/00 , A61K9/22
CPC分类号： A61B5/14528 , A61B5/14532 , A61B5/686 , A61B2562/0295 , Y10T436/110833
摘要： The present invention is generally directed towards devices for sensing a concentration of chemical constituents in body fluid such as interstitial fluid, including but not limited to glucose. The devices also relates to systems for measuring and reporting the concentration of body fluid constituents at time intervals shorter than the physiological response time, thereby providing effectively continuous concentration measurements. The device according to the present invention comprises a probe, a reservoir with perfusion fluid connected to an inlet of the probe, at least one test zones which comprise a reagent, to react with the analyte to produce a detectable change, a reader unit which reads test zones wetted with fluid containing the analyte, where the reader unit produces signals according to the concentration of the analyte in the fluid; and a processing unit for processing the signals and the concentration of the analyte.
摘要翻译：本发明通常涉及用于感测体液中诸如间质液体（包括但不限于葡萄糖）的化学成分浓度的装置。这些装置还涉及用于在比生理反应时间短的时间间隔测量和报告体液组分的浓度的系统，从而提供有效的连续浓度测量。根据本发明的装置包括探针，具有连接到探针的入口的灌注流体的储存器，包含试剂的至少一个测试区域，以与分析物反应以产生可检测的变化;读取器单元，其读取用含有分析物的流体润湿的测试区域，其中读取器单元根据流体中分析物的浓度产生信号; 以及用于处理信号和分析物浓度的处理单元。

85. 发明授权

US5692504A Method and apparatus for the analysis of glucose in a biological matrix 失效
标题翻译：用于分析生物基质中葡萄糖的方法和装置
公开(公告)号：US5692504A
公开(公告)日：1997-12-02
申请号：US592303
申请日：1996-02-09
申请人： Matthias Essenpreis , Dirk Boecker , Heinz-Michael Hein , Hans-Peter Haar
发明人： Matthias Essenpreis , Dirk Boecker , Heinz-Michael Hein , Hans-Peter Haar
IPC分类号： A61B5/145 , A61B5/00 , A61B5/1455 , G01N21/41 , G01N21/47 , G01N21/49 , A61B5/000
CPC分类号： A61B5/1455 , A61B5/14532 , G01N21/41 , G01N21/47 , G01N21/49 , A61B2562/0242 , G01N2201/0696
摘要： Method and apparatus for the analytical determination of glucose concentration in a biological matrix, wherein in a detection step light from a light emitter is irradiated into the biological matrix as primary light via a boundary surface of the biological matrix and light emerging from the the biological matrix through a boundary surface is being detected by a light detector in order to determine a measurable physical light property which is changed by interaction with the biological matrix and which correlates with the glucose concentration of said matrix. The glucose concentration is ascertained in an evaluation step on the basis of said change of the physical light property determined in at least one detection step in comparison with a calibration. In order to achieve by such a method good analytical accuracy in reagent-free and non-invasive manner, for instance to observe the change of the concentration of the analyzed substance (monitoring) over an adequate time interval, a measurable parameter corresponding to the light transit-time within the biological matrix between a defined irradiation site and a defined detection site and correlating with the glucose concentration is determined in the detection step.
摘要翻译： PCT No.PCT / DE94 / 01290 Sec。 371日期1996年2月9日 102（e）日期1996年2月9日PCT 1994年10月29日PCT PCT。 WO95 / 12348 PCT公开号日期：1995年5月11日用于生物基质中葡萄糖浓度分析测定的方法和装置，其中在检测步骤中，来自发光体的光经由生物基质的边界表面作为主要光照射到生物基质中，通过光检测器检测生物基质，以便确定通过与生物基质相互作用而改变并与所述基质的葡萄糖浓度相关的可测量的物理光特性。基于与校准相比在至少一个检测步骤中确定的物理光特性的变化，在评估步骤中确定葡萄糖浓度。为了通过这种方法实现无试剂和非侵入性的良好的分析精确性，例如在足够的时间间隔内观察分析物质（监测）浓度的变化，对应于光的可测量参数在检测步骤中确定在确定的照射位点和限定的检测位点之间的生物学基质内的与葡萄糖浓度相关的转运时间。

86. 发明授权

US5393391A Electrode arrangement for the electrochemical analysis of electrolytic components of a liquid 失效
标题翻译：用于液体电解组分电化学分析的电极装置
公开(公告)号：US5393391A
公开(公告)日：1995-02-28
申请号：US728768
申请日：1991-07-08
申请人： Werner Dietze , Hans-Peter Haar , Horst Herrmann , Dieter Knoll , Wolfgang Reiser
发明人： Werner Dietze , Hans-Peter Haar , Horst Herrmann , Dieter Knoll , Wolfgang Reiser
IPC分类号： G01N27/28 , G01N27/403 , G01N27/416 , G01N33/483 , G01N27/30
CPC分类号： G01N27/4035 , G01N27/4165
摘要： The present invention provides an electrode arrangement for the electrochemical analysis of components of a liquid, having a base body (7; 53; 85; 103; 139; 155; 175; 193), made of an insulating material with at least one measurement electrode (21; 57; 89; 111; 143; 157; 195) held on the base body, adapted to be brought into phase boundary contact with the liquid to be analysed, said measurement electrode being selective for a predetermined kind of ion in the liquid, and with at least one reference electrode (19; 55; 87; 109; 141; 153; 173; 197; 199) held on the base body and adapted to be brought into phase boundary contact, together with the measurement electrode, with the liquid, wherein the base body carries a removable closure part (45; 61; 91; 107; 137; 163; 187; 203) which, together with the base body, forms a closed hollow chamber (11; 52; 86; 104; 135; 159; 177; 201), the closed hollow chamber containing a standard electrolyte, especially one containing the predetermined kind of ion, defining, with the ion-selective measurement electrode, a predetermined half cell potential, said standard electrolyte being in phase boundary contact not only with the or each measurement electrode but also with the or each reference electrode.
摘要翻译：本发明提供了一种用于电化学分析液体组分的电极装置，其具有由具有至少一个测量电极的绝缘材料制成的基体（7; 53; 85; 103; 139; 155; 175; 193）（21; 57; 89; 111; 143; 157; 195），其保持在所述基体上，适于与所述待分析液体相界接触，所述测量电极对于所述液体中的预定种类的离子是选择性的以及保持在基体上并适于与测量电极一起进入相界接触的至少一个参考电极（19; 55; 87; 109; 141; 153; 173; 197; 199）液体，其中所述基体携带可移除的封闭部分（45; 61; 91; 107; 137; 163; 187; 203），所述可拆卸闭合部分与所述基体一起形成封闭的中空室（11; 52; 86; 104; 135; 159; 177; 201），封闭的中空室含有标准电解质，特别是含有预定类型的电解质的离子，用离子选择性测量电极限定预定的半电池电位，所述标准电解质不仅与测量电极或每个测量电极相位边界地接触，而且与所述或每个参比电极相接触。

87. 发明授权

US4329062A Polychromatic photometer 失效
标题翻译：多色光度计
公开(公告)号：US4329062A
公开(公告)日：1982-05-11
申请号：US164520
申请日：1980-07-02
申请人： Hans-Peter Haar , Hermann Edelmann , Sigmar Klose
发明人： Hans-Peter Haar , Hermann Edelmann , Sigmar Klose
IPC分类号： G01N21/27 , G01N21/13 , G01N21/25
CPC分类号： G01N21/13 , G01N21/253
摘要： In a polychromatic photometer a sample wheel containing angularly spaced sample compartments and a filter wheel containing angularly spaced filters are rotated by a common drive arrangement so that the sample compartments and filters are in turn rotated through and aligned with the optical path of a photometric measuring device. The number of sample compartments is different from the number of filters. The number of sample compartments and the number of filters are not evenly divisible by a common integer. The ratio of the angular velocity of the sample wheel to the angular velocity of the filter wheel is substantially equal to the ratio of the number of filters to the number of sample compartments.
摘要翻译：在多色光度计中，包含角度间隔开的样品室和包含角度间隔开的滤光器的滤光轮的样品轮通过公共驱动装置旋转，使得样品室和滤光器又旋转通过并与光度测量装置的光路对准。样品室的数量与过滤器的数量不同。样本室的数量和过滤器的数量不能被公共整数均分。样品轮的角速度与滤光轮的角速度的比率基本上等于滤光片数与样品室数之比。

88. 发明授权

US11510595B2 Tubular sensor for the detection of an analyte 有权
公开(公告)号：US11510595B2
公开(公告)日：2022-11-29
申请号：US12611579
申请日：2009-11-03
申请人： Karin Schwind , Hans-Peter Haar , Otto Fuerst
发明人： Karin Schwind , Hans-Peter Haar , Otto Fuerst
IPC分类号： A61B5/145 , A61B5/1486 , A61B5/00
摘要： An implantable sensor can be used for determining a concentration of at least one analyte in a medium, particularly in a body tissue and/or a body fluid. The implantable sensor can comprise a flexible, tubular sensor element. This sensor element has a tubular body on which at least two electrode rings are mounted for electrochemical determination of the concentration of the analyte.

89. 发明授权

US09746670B2 Device for presenting information near the eyes 有权
公开(公告)号：US09746670B2
公开(公告)日：2017-08-29
申请号：US13577050
申请日：2011-02-03
申请人： Jean-Michel Asfour , Hans-Peter Haar
发明人： Jean-Michel Asfour , Hans-Peter Haar
IPC分类号： G02B27/01 , F21V8/00 , G02B3/08
CPC分类号： G02B27/017 , G02B3/08 , G02B6/0006 , G02B6/0008 , G02B27/0172 , G02B2027/0118 , G02B2027/0132
摘要： The invention relates to a device for presenting information near the eyes, comprising a support (12) that can be carried on the head (10) of a user and comprising a monocular display unit (16) which is disposed on the support (12) and is positioned in a peripheral region of the field of vision of a first eye (14) of the user during use. According to a first aspect of the invention, a light-collecting unit (18, 20) on which ambient light can impinge is disposed on the support (12), and the light-collecting unit (18, 20) is coupled to the display unit (16) in order to illuminate same.

90. 发明授权

US09089293B2 Test element for analyzing a body fluid 有权
标题翻译：用于分析体液的测试元件
公开(公告)号：US09089293B2
公开(公告)日：2015-07-28
申请号：US13351496
申请日：2012-01-17
申请人： Hans-Peter Haar , Joachim Hoenes
发明人： Hans-Peter Haar , Joachim Hoenes
IPC分类号： G01N33/48 , A61B5/145
CPC分类号： A61B5/14532 , A61B2562/0295
摘要： A test element includes a puncture element and a test panel. The puncture element has a tip positioned at one end for generating a wound in a body part. A capillary structure extends from the tip to the test panel and has a fluid connection to the tip. The test panel contains at least a part of a reagent system and is positioned in the test element adjacent to a part of the capillary structure of the puncture element so that body fluid penetrating into the capillary structure contacts a liquid entry side of the test panel. The test panel comprises a transparent support layer and a test layer applied to the support layer by coating. The side of the test panel facing away from the support layer forms its liquid entry side, which faces toward the capillary structure.
摘要翻译：测试元件包括穿刺元件和测试面板。穿刺元件具有位于一端的尖端，用于在身体部分中产生伤口。毛细管结构从尖端延伸到测试面板，并且具有与尖端的流体连接。测试面板包含至少一部分试剂系统，并且位于与穿刺元件的毛细结构的一部分相邻的测试元件中，使得渗入毛细结构的体液接触测试面板的液体入口侧。测试板包括透明支撑层和通过涂覆施加到支撑层的测试层。测试面板背离支撑层的一侧形成面向毛细管结构的液体入口侧。

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