会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 81. 发明授权
    • Method of deriving standard 12-lead electrocardiogram and electrocardiogram monitoring apparatus
    • 推导标准12导联心电图和心电图监测仪的方法
    • US06721591B2
    • 2004-04-13
    • US09910837
    • 2001-07-24
    • Daming WeiTakeshi KojimaTadashi NakayamaYoshio Sakai
    • Daming WeiTakeshi KojimaTadashi NakayamaYoshio Sakai
    • A61B50402
    • A61B5/0006A61B5/04028A61B5/0404A61B5/0432
    • A plurality of electrodes for measuring electrocardiogarphic waveforms are attached on body surface positions that constitute a subset of the standard 12-lead system. The measured electrocardiogarphic waveforms of said subset of said standard 12-lead system are used to calculate the electrocardiogarphic waveforms of remaining leads in the said standard 12-lead system. The measured and calculated electrocardiographic waveforms are synthesized to form a standard 12-lead electrocardiogram. The invention is capable of monitoring the 12-lead electrocardiogram with a reduced number of electrodes, wherein a portion of waveforms are directly measured and used as primary information for diagnosing heart disease, and the other portion of waveforms are derived from the measured leads and are used as a secondary information for improving the accuracy of diagnosis. The invention is especially useful in monitoring ischemic heart disease and acute myocardial infarction in cases where mounting and maintaining ten electrodes to obtain 12-lead electrocardiogram is difficult, such as in ambulatory monitoring, long-term monitoring and home monitoring.
    • 用于测量心电波形波形的多个电极附着在构成标准12引导系统的子集的体表位置上。 所述标准12引导系统的所述子集的测量的心电图波形用于计算所述标准12引导系统中剩余引线的心电图波形。 合成测量和计算的心电图波形,形成标准的12导联心电图。 本发明能够以减少数量的电极监测12导联心电图,其中一部分波形被直接测量并用作用于诊断心脏病的主要信息,波形的另一部分来自测量引线,并且是 用作提高诊断准确度的次要信息。 本发明特别适用于监测缺血性心脏病和急性心肌梗死,如安装和维持十个电极获得12导联心电图难度较大,例如在动态监测,长期监测和家庭监测中。
    • 85. 发明授权
    • Self-locking knob for adjustable control mechanism
    • 自锁旋钮可调控制机构
    • US4955253A
    • 1990-09-11
    • US902045
    • 1986-08-26
    • Yoshio SakaiTakeshi Yamada
    • Yoshio SakaiTakeshi Yamada
    • H05B3/00G05G1/00G05G1/10G05G5/12G05G5/18
    • G05G1/10G05G5/18Y10S16/30Y10T16/506Y10T74/2066Y10T74/2084
    • A control mechanism having a dial and cooperating structure for selectively locking the dial in any one of a plurality of angularly related positions. The locking mechanism is configured to provide a force or manipulating characteristic precluding operation thereof by accident or by young children, such as infants, thereby effectively precluding undesired resetting of the associated control mechanism. The locking structure is formed integrally with the respective relatively movable parts of the mechanism, including the structure for providing the biasing of the locking mechanism to the locking disposition. The locking mechanism is resiliently biased and includes a graspable portion which when grasped to effect movement of the control overcomes the resilient biasing. The biasing structure automatically relocks the dial upon release of the graspable portion.
    • 一种具有拨盘和配合结构的控制机构,用于选择性地将表盘锁定在多个角度相关位置中的任一个中。 锁定机构被配置成提供强制或操纵特性,排除其意外或幼儿(例如婴儿)的操作,从而有效地排除相关联的控制机构的不期望的重置。 锁定结构与机构的各个可相对移动的部分一体地形成,包括用于提供锁定机构偏压到锁定配置的结构。 锁定机构被弹性地偏置并且包括可握持部分,当被抓握以实现控制的移动时克服了弹性偏压。 偏置结构在释放可抓握部分时自动重新拨盘。
    • 86. 发明授权
    • Detection of digestive organ cancer, gastric cancer, colorectal cancer, pancreatic cancer, and biliary tract cancer by gene expression profiling
    • 通过基因表达谱检测消化器官癌,胃癌,结肠直肠癌,胰腺癌和胆道癌
    • US08932990B2
    • 2015-01-13
    • US13391858
    • 2010-08-03
    • Shuichi KanekoMasao HondaYoshio SakaiTaro Yamashita
    • Shuichi KanekoMasao HondaYoshio SakaiTaro Yamashita
    • C40B30/04C12Q1/68C40B40/06
    • C12Q1/6886C12Q2600/158C12Q2600/16
    • The present invention provides a method and a reagent for detecting a digestive organ cancer, gastric cancer, colorectal cancer, pancreatic cancer, or biliary tract cancer patient by analyzing genes with expression levels (in peripheral blood) that vary in association with digestive organ cancer, gastric cancer, colorectal cancer, pancreatic cancer, or biliary tract cancer cases, compared with normal healthy subjects. Specifically, the method for detecting a digestive organ cancer, gastric cancer, colorectal cancer, pancreatic cancer, or biliary tract cancer patient based on expression profiles comprises obtaining the expression profile of at least one gene selected from the group consisting of probes corresponding to genes with expression levels (in peripheral blood) that vary in digestive organ cancer, gastric cancer, colorectal cancer, pancreatic cancer, and biliary tract cancer cases, compared with normal healthy subjects. The reagent for detecting digestive organ cancer, gastric cancer, colorectal cancer, pancreatic cancer, or biliary tract cancer contains nucleotides or partial sequences thereof consisting of the nucleotide sequence of at least one gene selected from the group consisting of probes with expression levels that vary in digestive organ cancer, gastric cancer, colorectal cancer, pancreatic cancer, or biliary tract cancer, or nucleotides containing sequences complementary thereto.
    • 本发明提供了通过分析与消化器官癌相关的变化的表达水平(外周血)的基因来检测消化器官癌,胃癌,结肠直肠癌,胰腺癌或胆道癌患者的方法和试剂, 胃癌,结肠直肠癌,胰腺癌或胆道癌,与正常健康人相比。 具体地,基于表达谱,检测消化器官癌,胃癌,结肠直肠癌,胰腺癌或胆道癌患者的方法包括获得至少一种基因的表达谱,所述基因选自对应于具有 与正常健康受试者相比,消化器官癌,胃癌,结肠直肠癌,胰腺癌和胆道癌患者的表达水平(外周血)差异不大。 用于检测消化器官癌,胃癌,结肠直肠癌,胰腺癌或胆道癌的试剂含有由至少一种基因的核苷酸序列组成的核苷酸或其部分序列,所述核苷酸序列选自下组的探针:表达水平在 消化器官癌,胃癌,结肠直肠癌,胰腺癌或胆道癌,或含有与其互补的序列的核苷酸。