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81. 发明申请

US20120060601A1 TETHERED FLOAT LIQUID LEVEL SENSOR 有权
标题翻译： TETHERED FLOAT液位传感器
公开(公告)号：US20120060601A1
公开(公告)日：2012-03-15
申请号：US12882913
申请日：2010-09-15
申请人： William Dean Daily, III
发明人： William Dean Daily, III
IPC分类号： G01F23/30
CPC分类号： G01F23/40 , G01F23/42 , G01F23/44 , G01F23/443 , G01F23/446
摘要： An apparatus for sensing the level of a liquid includes a float, a tether attached to the float, a pulley attached to the tether, a rotation sensor connected to the pulley that senses vertical movement of said float and senses the level of the liquid.
摘要翻译：用于感测液体水平的装置包括浮子，附接到浮子的系绳，连接到系绳的滑轮，连接到滑轮的旋转传感器，其感测所述浮子的垂直运动并感测液体的水平。

82. 发明授权

US08076266B2 Urea phosphite fungicide 有权
标题翻译：尿素亚磷酸盐杀真菌剂
公开(公告)号：US08076266B2
公开(公告)日：2011-12-13
申请号：US12316190
申请日：2008-12-10
申请人： Frank William Dean
发明人： Frank William Dean
IPC分类号： A01N25/26 , A01N57/00
CPC分类号： A01N59/04 , A01N59/26 , C05C9/00 , C05G3/02
摘要： Urea Phosphite is a new composition of matter useful as a fertilizer and as a fungicide. It is made by reacting phosphorous acid with urea. Urea Phosphite is characterized by being a liquid produced in an unprocessed reaction, and by having phosphite as a phosphorus source and urea as a nitrogen source. The reaction products may be separated, blended with an admix and spray dried, or dissolved in water. This new composition of matter avoids the pitfalls of pathological acerbation reported with the use of phosphite fertilizers and fungicides. When blended with an admix, this new composition is also believed to have the ability to break dormancy in temperate fruiting crops.
摘要翻译：尿素亚磷酸盐是用作肥料和杀真菌剂的新物质组合物。它是通过使亚磷酸与尿素反应制成的。尿素亚磷酸酯的特征在于在未加工的反应中产生的液体，并且通过使亚磷酸酯作为磷源和尿素作为氮源。反应产物可以分离，混合并喷雾干燥，或溶于水。这种新的物质组成避免了使用亚磷酸盐肥料和杀真菌剂报告的病理性疼痛的陷阱。当与混合物混合时，这种新的组合物也被认为具有在温带的果实作物中破坏休眠的能力。

83. 发明申请

US20110182884A1 P-CADHERIN ANTIBODIES 有权
标题翻译： P-CADHERIN抗体
公开(公告)号：US20110182884A1
公开(公告)日：2011-07-28
申请号：US13079726
申请日：2011-04-04
申请人： Christopher Todd Bauer , Maureen Jeri Bourner , Melanie Boyle , Gerald Fries Casperson , David William Griggs , Richard David Head , William Dean Joy , Richard Allen Mazzarella , Ralph Raymond Minter , Mark Allen Moffat , Barrett Richard Thiele , Todd Lee Vanarsdale
发明人： Christopher Todd Bauer , Maureen Jeri Bourner , Melanie Boyle , Gerald Fries Casperson , David William Griggs , Richard David Head , William Dean Joy , Richard Allen Mazzarella , Ralph Raymond Minter , Mark Allen Moffat , Barrett Richard Thiele , Todd Lee Vanarsdale
IPC分类号： A61K39/395 , C07K16/18 , A61P35/00 , A61P35/02
CPC分类号： C07K16/28 , C07K2317/21 , C07K2317/565 , C07K2317/622 , C07K2317/76 , C07K2317/92 , Y02P20/582
摘要： The present invention relates to antibodies including human antibodies and antigen-binding portions thereof that bind to P-cadherin, and that function to inhibit P-cadherin. The invention also relates to heavy and light chain immunoglobulins derived from human P-cadherin antibodies and nucleic acid molecules encoding such immunoglobulins. The present invention also relates to methods of making human P-cadherin antibodies, compositions comprising these antibodies and methods of using the antibodies and compositions. The invention also relates to transgenic animals or plants comprising nucleic acid molecules of the present invention.
摘要翻译：本发明涉及结合P-钙粘蛋白的人抗体及其抗原结合部分的抗体，其功能是抑制P-钙粘蛋白。本发明还涉及衍生自人P-钙粘蛋白抗体的重链和轻链免疫球蛋白和编码这种免疫球蛋白的核酸分子。本发明还涉及制备人P-钙粘蛋白抗体的方法，包含这些抗体的组合物和使用抗体和组合物的方法。本发明还涉及包含本发明的核酸分子的转基因动物或植物。

84. 发明授权

US07928214B2 P-cadherin antibodies 有权
标题翻译： P-钙粘蛋白抗体
公开(公告)号：US07928214B2
公开(公告)日：2011-04-19
申请号：US12249843
申请日：2008-10-10
申请人： Christopher Todd Bauer , Maureen Jeri Bourner , Melanie Boyle , Gerald Fries Casperson , David William Griggs , Richard David Head , William Dean Joy , Richard Allen Mazzarella , Ralph Raymond Minter , Mark Allen Moffat , Barrett Richard Thiele , Todd Lee Vanarsdale
发明人： Christopher Todd Bauer , Maureen Jeri Bourner , Melanie Boyle , Gerald Fries Casperson , David William Griggs , Richard David Head , William Dean Joy , Richard Allen Mazzarella , Ralph Raymond Minter , Mark Allen Moffat , Barrett Richard Thiele , Todd Lee Vanarsdale
IPC分类号： C07H21/04
CPC分类号： C07K16/28 , C07K2317/21 , C07K2317/565 , C07K2317/622 , C07K2317/76 , C07K2317/92 , Y02P20/582
摘要： The present invention relates to antibodies including human antibodies and antigen-binding portions thereof that bind to P-cadherin, and that function to inhibit P-cadherin. The invention also relates to heavy and light chain immunoglobulins derived from human P-cadherin antibodies and nucleic acid molecules encoding such immunoglobulins. The present invention also relates to methods of making human P-cadherin antibodies, compositions comprising these antibodies and methods of using the antibodies and compositions. The invention also relates to transgenic animals or plants comprising nucleic acid molecules of the present invention.
摘要翻译：本发明涉及结合P-钙粘蛋白的人抗体及其抗原结合部分的抗体，其功能是抑制P-钙粘蛋白。本发明还涉及衍生自人P-钙粘蛋白抗体的重链和轻链免疫球蛋白和编码这种免疫球蛋白的核酸分子。本发明还涉及制备人P-钙粘蛋白抗体的方法，包含这些抗体的组合物和使用抗体和组合物的方法。本发明还涉及包含本发明的核酸分子的转基因动物或植物。

85. 发明申请

US20090312325A1 Quinoline Derivatives As Phosphodiesterase Inhibitors 审中-公开
标题翻译：喹啉衍生物作为磷酸二酯酶抑制剂
公开(公告)号：US20090312325A1
公开(公告)日：2009-12-17
申请号：US12474324
申请日：2009-05-29
申请人： Ian Robert Baldwin , Michael David Barker , Anthony William Dean , Colin David Eldred , Brian Evans , Sharon Lisa Gough , Stephen Barry Guntrip , Julie Nicole Hamblin , Stuart Holman , Paul Jones , Mika Kristian Lindvall , Christopher James Lunniss , Tracy Jane Redfern , Alison Judith Redgrave , John Edward Robinson , Michael Woodrow
发明人： Ian Robert Baldwin , Michael David Barker , Anthony William Dean , Colin David Eldred , Brian Evans , Sharon Lisa Gough , Stephen Barry Guntrip , Julie Nicole Hamblin , Stuart Holman , Paul Jones , Mika Kristian Lindvall , Christopher James Lunniss , Tracy Jane Redfern , Alison Judith Redgrave , John Edward Robinson , Michael Woodrow
IPC分类号： A61K31/4709 , C07D401/12 , C07D417/12 , C07D403/12 , C07D215/38 , A61K31/47 , A61K31/5377 , A61P29/00 , A61P37/08
CPC分类号： C07D401/12 , C07D215/54 , C07D401/14 , C07D405/12 , C07D405/14 , C07D409/12 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14 , C07D453/02
摘要： There are provided according to the invention novel compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein R1, R2, R19, R20, and R34 are as described in the specification, processes for preparing them, formulations containing them and their use in therapy for the treatment of inflammatory diseases.
摘要翻译：根据本发明提供新的式（I）化合物或其药学上可接受的盐，其中R1，R2，R19，R20和R34如说明书中所述，其制备方法，含有它们的制剂及其在治疗炎症性疾病。

86. 发明授权

US07572915B2 Quinoline derivatives as phosphodiesterase inhibitors 失效
公开(公告)号：US07572915B2
公开(公告)日：2009-08-11
申请号：US11349677
申请日：2006-02-08
申请人： Michael David Barker , Anthony William Dean , Brian Evans , Stuart Holman , Michael Woodrow
发明人： Michael David Barker , Anthony William Dean , Brian Evans , Stuart Holman , Michael Woodrow
IPC分类号： C07D215/38
CPC分类号： C07D401/12 , C07D215/54 , C07D401/14 , C07D405/12 , C07D405/14 , C07D409/12 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14 , C07D453/02
摘要： There are provided according to the invention novel compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein R1, R2, R19, R20, and R34 are as described in the specification, processes for preparing them, formulations containing them and their use in therapy for the treatment of inflammatory diseases.

87. 发明申请

US20090095040A1 Urea phosphite fertilizer 有权
标题翻译：尿素亚磷酸盐肥
公开(公告)号：US20090095040A1
公开(公告)日：2009-04-16
申请号：US12284393
申请日：2008-09-22
申请人： Frank William Dean
发明人： Frank William Dean
IPC分类号： C05B15/00
CPC分类号： C05B15/00 , A01N59/04 , A01N59/26 , C05C9/00 , C05G3/02 , Y02P60/218
摘要： A new fertilizer comprising Urea Phosphite, which is made by reacting phosphorous acid with urea. Urea Phosphite is characterized by being a liquid produced in an unprocessed reaction, and by having phosphite as a phosphorus source and urea as a nitrogen source. The reaction product may be blended with an admix and spray dried, or dissolved in water.
摘要翻译：一种由磷酸与尿素反应制成的亚磷酸尿素的新型肥料。尿素亚磷酸酯的特征在于在未加工的反应中产生的液体，并且通过使亚磷酸酯作为磷源和尿素作为氮源。反应产物可以混合并喷雾干燥或溶于水中。

88. 发明授权

US07452537B2 P-cadherin antibodies 有权
标题翻译： P-钙粘蛋白抗体
公开(公告)号：US07452537B2
公开(公告)日：2008-11-18
申请号：US11410610
申请日：2006-04-25
申请人： Christopher Todd Bauer , Maureen Jeri Bourner , Melanie Boyle , Gerald Fries Casperson , David William Griggs , Richard David Head , William Dean Joy , Richard Allen Mazzarella , Ralph Raymond Minter , Mark Allen Moffat , Barrett Richard Thiele , Todd Lee Vanarsdale
发明人： Christopher Todd Bauer , Maureen Jeri Bourner , Melanie Boyle , Gerald Fries Casperson , David William Griggs , Richard David Head , William Dean Joy , Richard Allen Mazzarella , Ralph Raymond Minter , Mark Allen Moffat , Barrett Richard Thiele , Todd Lee Vanarsdale
IPC分类号： A61K39/00 , C07K16/00
CPC分类号： C07K16/28 , C07K2317/21 , C07K2317/565 , C07K2317/622 , C07K2317/76 , C07K2317/92 , Y02P20/582
摘要： The present invention relates to antibodies including human antibodies and antigen-binding portions thereof that bind to P-cadherin, and that function to inhibit P-cadherin. The invention also relates to heavy and light chain immunoglobulins derived from human P-cadherin antibodies and nucleic acid molecules encoding such immunoglobulins. The present invention also relates to methods of making human P-cadherin antibodies, compositions comprising these antibodies and methods of using the antibodies and compositions. The invention also relates to transgenic animals or plants comprising nucleic acid molecules of the present invention.
摘要翻译：本发明涉及结合P-钙粘蛋白的人抗体及其抗原结合部分的抗体，其功能是抑制P-钙粘蛋白。本发明还涉及衍生自人P-钙粘蛋白抗体的重链和轻链免疫球蛋白和编码这种免疫球蛋白的核酸分子。本发明还涉及制备人P-钙粘蛋白抗体的方法，包含这些抗体的组合物和使用抗体和组合物的方法。本发明还涉及包含本发明的核酸分子的转基因动物或植物。

89. 发明申请

US20070276891A1 Pulse Output Direct Digital Synthesis Circuit 有权
标题翻译：脉冲输出直接数字合成电路
公开(公告)号：US20070276891A1
公开(公告)日：2007-11-29
申请号：US11754325
申请日：2007-05-28
申请人： William Dean Warner , Richard Edmund Ryan
发明人： William Dean Warner , Richard Edmund Ryan
IPC分类号： G06F1/02
CPC分类号： G06F1/025
摘要： A clock signal generator responsive to a frequency control word and a reference clock signal having a reference clock frequency fref. The clock signal generator generates an output clock signal having a frequency fgen, wherein fgen is less than fref. A modulo-N counter accepts the reference clock signal as input. The modulo-N counter generates a phase-indication signal of the reference clock. The phase indication signal has N clock phases repeating at a frequency of fref/N. An accumulator iteratively accumulates a frequency control word into a modulo-N adder and produces an accumulated value. One or more bits of the accumulated value is fed-back into the modulo-N adder for adding modulo N to the accumulated value in the next iteration. N of the modulo-N adder is the same integer as in the modulo-N counter. A clock edge selector receives as inputs the phase indication signal and one or more bits of the accumulated value and by comparing the inputs selects an edge of the reference clock signal upon which to toggle the state of the output clock signal. The clock edge selector preferably selects the edge from: (i) only rising edges of the reference clock signal, (ii) only falling edges of the reference clock signal or (iii) both rising and falling edges of the reference clock signal. The clock edge selector selects between a rising edge and a falling edge of the reference clock signal preferably based on one or more bits of the accumulated value.
摘要翻译：响应于频率控制字的时钟信号发生器和具有参考时钟频率f ref的参考时钟信号。时钟信号发生器产生一个具有频率f IN的输出时钟信号，其中f _{小于f ref。模N计数器接受参考时钟信号作为输入。模N计数器产生参考时钟的相位指示信号。相位指示信号具有以f ref / N的频率重复的N个时钟相位。累加器将频率控制字迭代地累加到模N加法器中并产生累加值。将累加值的一个或多个位反馈到模N加法器中，以在下一次迭代中将模N加到累加值。模N加法器的N与模N计数器中的整数相同。时钟沿选择器接收相位指示信号和累加值的一个或多个比特作为输入，并且通过比较输入来选择参考时钟信号的边沿以触发输出时钟信号的状态。时钟沿选择器优选地从以下选择边缘：（i）仅参考时钟信号的上升沿，（ii）仅参考时钟信号的下降沿或（iii）参考时钟信号的上升沿和下降沿。时钟沿选择器优选地基于累加值的一个或多个比特在参考时钟信号的上升沿和下降沿之间进行选择。}

90. 发明授权

US07255649B1 Golf putting distance control training device 失效
标题翻译：高尔夫球距离控制训练装置
公开(公告)号：US07255649B1
公开(公告)日：2007-08-14
申请号：US10675366
申请日：2003-09-30
申请人： William Dean McConnell
发明人： William Dean McConnell
IPC分类号： A63B57/00 , A63B69/36
CPC分类号： A63B69/3676 , A63B24/0021 , A63B69/3658 , A63B2024/0037 , A63B2071/0694 , A63B2220/802 , A63B2220/808 , A63B2220/89
摘要： A golf putting training device is provided which allows a golfer to practice distance control in a confined area by displaying an estimate of how far a golf ball would have traveled on a green having a selected stimp value after being struck with a putter and subsequently colliding with a target strike plate of the training device. The golf putting training device includes a housing and rear stabilization plate, a target strike plate, a doppler microwave speed sensor, an impact sensor, a green speed selector, a distance display, an audible beeper, and a microcontroller which calculates the putting distance based on the measurement of the speed of the rolling golf ball prior to impact and the stimp setting selected. An audible beeper provides an indication of the rolling progress of the simulated roll of the golf ball past the target strike plate.
摘要翻译：提供了一种高尔夫球训练装置，其允许高尔夫球手在受限区域中实施距离控制，通过显示高尔夫球在被推杆之后具有选定的刺激值的绿色将前进的距离的估计，并且随后与训练装置的目标打击板。高尔夫球训练装置包括壳体和后稳定板，目标撞击板，多普勒微波速度传感器，冲击传感器，绿速选择器，距离显示器，听觉蜂鸣器以及计算放置距离的微控制器在冲击之前滚动高尔夫球的速度的测量和所选择的刺激设置。可听见的蜂鸣器提供了高尔夫球的模拟滚动通过目标撞击板的滚动进度的指示。

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