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81. 发明申请

US20120046336A1 METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION 有权
标题翻译：改进认知功能的方法和组合
公开(公告)号：US20120046336A1
公开(公告)日：2012-02-23
申请号：US13287531
申请日：2011-11-02
申请人： Michela Gallagher , Rebecca Haberman , Ming Teng Koh
发明人： Michela Gallagher , Rebecca Haberman , Ming Teng Koh
IPC分类号： A61K31/4015 , C07D207/27 , A61P25/28
CPC分类号： A61K31/4015 , A61K31/19 , A61K31/20 , A61K2300/00
摘要： This invention relates to treating age-related cognitive impairment. This invention in particular relates to the use of inhibitors of synaptic vesicle protein 2A (SV2A), such as levetiracetam, seletracetam, and brivaracetam, in improving cognitive function in subjects that exhibit age-related cognitive impairment or are at risk thereof, including, without limitation, subjects having or at risk for Mild Cognitive Impairment (MCI), Age-related Cognitive Decline (ARCD) or Age-Associated Memory Impairment (AAMI).
摘要翻译：本发明涉及治疗年龄相关的认知障碍。本发明特别涉及突触小泡蛋白2A（SV2A）的抑制剂，如左乙拉西坦，西洛西坦和布立西坦，用于改善患有年龄相关认知障碍或处于危险中的受试者的认知功能，包括没有限制，具有轻度认知障碍（MCI）或年龄相关认知衰退（ARCD）或年龄相关记忆障碍（AAMI）风险的受试者。

82. 发明申请

US20110245315A1 INDOLYL OR INDOLINYL HYDROXAMATE COMPOUNDS 有权
标题翻译：吲哚或吲哚啉酸羟化物化合物
公开(公告)号：US20110245315A1
公开(公告)日：2011-10-06
申请号：US13074312
申请日：2011-03-29
申请人： Ching-Shih Chen , Jing-Ping Liou , Hsing-Jin Liu , Kuo-Sheng Hung , Pei-Wen Shan , Wen-Ta Chiu , Che-Ming Teng
发明人： Ching-Shih Chen , Jing-Ping Liou , Hsing-Jin Liu , Kuo-Sheng Hung , Pei-Wen Shan , Wen-Ta Chiu , Che-Ming Teng
IPC分类号： A61K31/4045 , C07D209/08 , A61P35/00
CPC分类号： C07D209/08 , C07D209/12 , C07D209/18 , C07D209/30 , C07D209/40
摘要： Indolyl or indolinyl compounds of formula (I): wherein bond, n, R1, R2, R3, R4, R5, and R6, are defined herein. Also disclosed is a method for treating cancer with these compounds.
摘要翻译：式（I）的吲哚基或二氢吲哚基化合物：其中键，n，R 1，R 2，R 3，R 4，R 5和R 6在本文中定义。还公开了用这些化合物治疗癌症的方法。

83. 发明授权

US07997296B2 Air valve device 失效
标题翻译：空气阀装置
公开(公告)号：US07997296B2
公开(公告)日：2011-08-16
申请号：US12285910
申请日：2008-10-16
申请人： Ming Teng
发明人： Ming Teng
IPC分类号： F16K15/20
CPC分类号： F16K15/20 , F16K15/06 , F16K15/18 , Y10T137/3646 , Y10T137/3755 , Y10T137/3771 , Y10T137/778 , Y10T137/7839
摘要： An outdoor lighting device includes a housing, at least one power supply device and at least one arrayed lighting unit. The housing has a surface forming at least one reflection zone and the reflection zone includes a lens. The power supply device is arranged inside the housing and has a grounding terminal connected to the housing. The power supply device receives and converts an alternate current power into an output of direct current power. The arrayed lighting unit includes plural arrays of lighting elements and a light-transmitting protection layer. The arrayed lighting unit is arranged inside the housing at a location corresponding to the lens and is connected to the power supply device, whereby the power supply device provides the arrayed lighting unit with the direct current power to energize the arrayed lighting unit to give off light that is reflected by the reflection zone. As such, an outdoor lighting device containing therein an arrayed lighting unit and an internal built-in power supply device is formed.
摘要翻译：室外照明装置包括壳体，至少一个电源装置和至少一个排列的照明单元。壳体具有形成至少一个反射区域的表面，并且反射区域包括透镜。电源装置布置在壳体内部，并具有连接到壳体的接地端子。电源装置接收并将交流电力转换为直流电力的输出。排列的照明单元包括多个照明元件阵列和透光保护层。排列的照明单元布置在壳体内的与透镜相对应的位置处并且连接到电源装置，由此电源装置向排列的照明单元提供直流电力以激励阵列照明单元以发出光这反映在反射区。因此，形成包含阵列照明单元和内置电源装置的户外照明装置。

84. 发明申请

US20110186412A1 TIMER 失效
标题翻译：定时器
公开(公告)号：US20110186412A1
公开(公告)日：2011-08-04
申请号：US12696360
申请日：2010-01-29
申请人： Ming Teng Chu , Shih Chi Chan
发明人： Ming Teng Chu , Shih Chi Chan
IPC分类号： H01H43/10
CPC分类号： H01H43/10
摘要： A timer includes a case, a shaft, a cam wheel, a drive mechanism, and a plurality of switch blades disposed within the case. The shaft is rotatably and reciprocally movably disposed in the case. The cam wheel is pivoted on the shaft and rotates together with the shaft when setting, or rotates independently by the drive mechanism. The cam wheel includes a plurality of cam tracks on one side surface thereof and a plurality of ratchets and grooves on a circular rim thereof. The drive mechanism contacts the ratchets to drive the cam wheel to rotate relative to the shaft. The switch blades respectively contact the cam tracks of the cam wheel, and correspondingly generate an electrical connection/disconnection. When the shaft moves to the setting position and the cam wheel being rotated by the user, a flexible element touches the grooves formed on the circular rim results a tactile feedback.
摘要翻译：定时器包括壳体，轴，凸轮，驱动机构和设置在壳体内的多个开关叶片。该轴可旋转地并且可往复运动地设置在壳体中。凸轮在轴上转动并与轴一起旋转，或者通过驱动机构独立地旋转。凸轮包括在其一个侧表面上的多个凸轮轨道和在其圆形边缘上的多个棘轮和凹槽。驱动机构接触棘轮以驱动凸轮相对于轴旋转。开关叶片分别接触凸轮的凸轮轨道，并相应地产生电连接/断开。当轴移动到设定位置并且凸轮由用户旋转时，柔性元件接触形成在圆形边缘上的凹槽产生触觉反馈。

85. 发明授权

US07767707B2 Fused pyrazolyl compounds having an aminoalkylcarbonyl group 有权
标题翻译：具有氨基烷基羰基的稠合的吡唑基化合物
公开(公告)号：US07767707B2
公开(公告)日：2010-08-03
申请号：US12292160
申请日：2008-11-13
申请人： Sheng-Chu Kuo , Che-Ming Teng , Fang-Yu Lee
发明人： Sheng-Chu Kuo , Che-Ming Teng , Fang-Yu Lee
IPC分类号： A61K31/416 , C07D231/56
CPC分类号： C07D405/04
摘要： A fused pyrazolyl compound having an anti-tumor potency of the following formula is synthesized: wherein A is in which n is 0, 1, 2, or 3; Ar1 is benzene, thiophene or furan; Ar2 is furyl; and Ar3 is phenyl; R1 and R2 independently are hydrogen, halogen or —(CH2)mORe; R3 is hydrogen or alkyl; R4 is —(CH2)r-A1, wherein r is an integer of 1-5, and A1 has a formula of —O—C(O)—(CRcH)q—NRc′Rd′; R5 and R6 independently are hydrogen, halogen, or alkyl, or R5 and R6 together are —O(CH2)mO—; Rc is H, halogen, nitro, cyano, alkyl, or aryl; Re is H, alkyl, or aryl; Rc′ and Rd′ independently are H, alkyl, or aryl; m is 0, 1, 2, 3, 4, 5, or 6; and q is 1, 2, 3, 4, 5, or 6; or a salt thereof.
摘要翻译：合成具有下式的抗肿瘤效力的稠合吡唑基化合物：其中A为n为0,1,2或3; Ar1为苯，噻吩或呋喃; Ar2是呋喃基; 和Ar 3是苯基; R1和R2独立地是氢，卤素或 - （CH2）mORe; R3是氢或烷基; R4是 - （CH2）r-A1，其中r是1-5的整数，并且A1具有下式的-O-C（O） - （CRcH）q-NRc'Rd'; R5和R6独立地是氢，卤素或烷基，或R5和R6一起是-O（CH2）mO-; Rc是H，卤素，硝基，氰基，烷基或芳基; Re为H，烷基或芳基; Rc'和Rd'独立地是H，烷基或芳基; m为0,1,2,3,4,5或6; q为1,2,3,4,5或6; 或其盐。

86. 发明授权

US07754751B2 Preferential inhibition of release of pro-inflammatory cytokines 失效
标题翻译：优先抑制促炎细胞因子的释放
公开(公告)号：US07754751B2
公开(公告)日：2010-07-13
申请号：US11080384
申请日：2005-03-15
申请人： Che-Ming Teng , Jih-Hwa Guh , Shiow-Lin Pan , Sheng-Chu Kuo , Fang-Yu Lee
发明人： Che-Ming Teng , Jih-Hwa Guh , Shiow-Lin Pan , Sheng-Chu Kuo , Fang-Yu Lee
IPC分类号： A01N43/56 , C07D231/10 , C07D231/12
CPC分类号： A61K31/4162 , A61K31/415
摘要： A method for preferentially inhibiting release of pro-inflammatory cytokines over release of anti-inflammatory cytokines using a fused pyrazolyl compound of formula (I): A is R or in which R is H, alkyl, aryl, cyclyl, heteroaryl, or heterocyclyl; each of Ar1, Ar2, and Ar3, independently, is phenyl, thienyl, furyl, or pyrrolyl; each of R1, R2, R3, R4, R5, and R6, independently, is R′, nitro, halogen, —C(O)—OR′, —C(O)—SR′, —C(O)—NR′R″, —(CH2)mOR′, —(CH2)mSR′, —(CH2)mNR′R″, —(CH2)mCN, —(CH2)mC(O)—OR′, —(CH2)mC(O)H, or R1 and R2 together, R3 and R4 together, or R5 and R6 together are —O(CH2)nO—, in which each of R′ and R″, independently, is H, alkyl, cyclyl, aryl, heteroaryl, heterocyclyl; and m is 0, 1, 2, 3, 4, 5, or 6; and n is 1, 2, or 3. This invention also covers a method of inhibiting activity of NF-κB with such a compound.
摘要翻译：使用式（I）的稠合吡唑基化合物优先抑制促炎细胞因子释放超过抗炎细胞因子释放的方法：A是R或其中R是H，烷基，芳基，环基，杂芳基或杂环基; Ar 1，Ar 2和Ar 3各自独立地是苯基，噻吩基，呋喃基或吡咯基; R 1，R 2，R 3，R 4，R 5和R 6各自独立地是R'，硝基，卤素，-C（O）-OR'， - C（O）-SR' “（CH 2）m R”， - （CH 2）m SRR'， - （CH 2）m NR R'， - （CH 2）m CN， - （CH 2）m C（O）（O）H，或R 1和R 2一起，R 3和R 4一起，或者R 5和R 6一起是-O（CH 2）n O-，其中R'和R“各自独立地是H，烷基，环基，芳基，杂芳基，杂环基; m为0,1,2,3,4,5或6; 并且n为1,2或3.本发明还涵盖了用这种化合物抑制NF-κB活性的方法。

87. 发明申请

US20100096572A1 Air Valve 审中-公开
标题翻译：气阀
公开(公告)号：US20100096572A1
公开(公告)日：2010-04-22
申请号：US12285898
申请日：2008-10-16
申请人： Ming Teng
发明人： Ming Teng
IPC分类号： F16K35/00 , F16K31/50
CPC分类号： F16K15/20
摘要： An air valve includes a tubular seat, a cap, and a plug. The tubular seat has an outer circumferential surface forming sealing slots, first external thread and second external thread and also forms an axially-extending air passage. The cap has an inside circumferential surface forming first internal thread, second internal thread, and a barrier web. The barrier web forms a bore and a plurality of air holes. The cap has a distal open end to which a lid is mounted. The plug has an expanded proximal end to which a sealing pad is attached and a reduced section slidably received in the bore of the barrier web and having a distal end to which a stop is mounted so that the plug is axially movable with respect to the barrier web. The cap is screwed onto the tubular seat and is selectively set at different axial locations so that the sealing pad is selectively set in engagement with or disengagement from the air passage to selectively set the air valve in a primary closing condition, where sealing is ensured and leaking of air is prevented, an open condition, where air is allow to freely flow into and out of the air valve, and an air releasing condition, where air is only allowed to flow out of the air valve.
摘要翻译：空气阀包括管状座，盖和塞。管状座具有形成密封槽，第一外螺纹和第二外螺纹的外圆周表面，并且还形成轴向延伸的空气通道。盖具有形成第一内螺纹，第二内螺纹和阻挡网的内圆周表面。阻挡网形成孔和多个气孔。盖具有远侧开口端，盖子安装到该远端开口端。插头具有扩展的近端，密封垫被附接到该近端，并且减小的部分可滑动地容纳在阻挡织物的孔中并且具有远端，止动件安装到该远端，使得插塞可相对于屏障轴向移动网络盖被拧到管状座上，并且被选择性地设置在不同的轴向位置，使得密封垫被选择性地设置成与空气通道接合或分离，以选择性地将空气阀设置在初级关闭状态，其中确保了密封，防止空气泄漏，空气允许自由流入和流出空气阀的打开状态，以及仅允许空气从空气阀流出的空气释放状态。

88. 发明申请

US20090254706A1 METHOD AND SYSTEM FOR APPROXIMATING OBJECT SIZES IN AN OBJECT-ORIENTED SYSTEM 失效
标题翻译：面向对象系统中对象大小的方法和系统
公开(公告)号：US20090254706A1
公开(公告)日：2009-10-08
申请号：US12098574
申请日：2008-04-07
申请人： Tian Cheng Liu , Qi Ming Teng , Susan P. Paice , Andrew J Schofield
发明人： Tian Cheng Liu , Qi Ming Teng , Susan P. Paice , Andrew J Schofield
IPC分类号： G06F12/00
CPC分类号： G06F9/4488 , G06F12/0802
摘要： A method and system for increasing a system's performance and achieving improved memory utilization by approximating the memory sizes that will be required for data objects that can be deserialized and constructed in a memory cache. The method and system may use accurate calculations or measurements of similar objects to calibrate the approximate memory sizes.
摘要翻译：一种用于通过近似可以在存储器高速缓存中反序列化和构造的数据对象所需的存储器大小来增加系统性能并实现改进的存储器利用的方法和系统。该方法和系统可以使用类似对象的精确计算或测量来校准大致的存储器大小。

89. 发明申请

US20090131681A1 Novel fused pyrazolyl compounds having an aminoalkylcarbonyl group 有权
标题翻译：具有氨烷基羰基的新型稠合吡唑基化合物
公开(公告)号：US20090131681A1
公开(公告)日：2009-05-21
申请号：US12292160
申请日：2008-11-13
申请人： Sheng-Chu Kuo , Che-Ming Teng , Fang-Yu Lee
发明人： Sheng-Chu Kuo , Che-Ming Teng , Fang-Yu Lee
IPC分类号： C07D405/04
CPC分类号： C07D405/04
摘要： A fused pyrazolyl compound having an anti-tumor potency of the following formula is synthesized: wherein A is in which n is 0, 1, 2, or 3; Ar1 is benzene, thiophene or furan; Ar2 is furyl; and Ar3 is phenyl; R1 and R2 independently are hydrogen, halogen or —(CH2)mORe; R3 is hydrogen or alkyl; R4 is —(CH2)r-A1, wherein r is an integer of 1-5, and A1 has a formula of —O—C(O)—(CRcH)q—NRc′Rd′; R5 and R6 independently are hydrogen, halogen, or alkyl, or R5 and R6 together are —O(CH2)mO—; Rc is H, halogen, nitro, cyano, alkyl, or aryl; Re is H, alkyl, or aryl; Rc′ and Rd′ independently are H, alkyl, or aryl; m is 0, 1, 2, 3, 4, 5, or 6; and q is 1, 2, 3, 4, 5, or 6; or a salt thereof.
摘要翻译：合成具有下式的抗肿瘤效力的稠合吡唑基化合物：其中A为n为0,1,2或3; Ar1为苯，噻吩或呋喃; Ar2是呋喃基; 和Ar 3是苯基; R1和R2独立地是氢，卤素或 - （CH2）mORe; R3是氢或烷基; R4是 - （CH2）r-A1，其中r是1-5的整数，并且A1具有下式的-O-C（O） - （CRcH）q-NRc'Rd'; R5和R6独立地是氢，卤素或烷基，或R5和R6一起是-O（CH2）mO-; Rc是H，卤素，硝基，氰基，烷基或芳基; Re为H，烷基或芳基; Rc'和Rd'独立地是H，烷基或芳基; m为0,1,2,3,4,5或6; q为1,2,3,4,5或6; 或其盐。

90. 发明申请

US20090038924A1 AUTOMATIC TIMING SWITCH DEVICE 审中-公开
标题翻译：自动定时开关装置
公开(公告)号：US20090038924A1
公开(公告)日：2009-02-12
申请号：US11835497
申请日：2007-08-08
申请人： Keng-Jen LAI , Ming-Teng CHU , Shih-Chi CHAN
发明人： Keng-Jen LAI , Ming-Teng CHU , Shih-Chi CHAN
IPC分类号： H01H7/08
CPC分类号： H01H43/101
摘要： An automatic timing switch device includes a switch control wheel, a driving assembly, and a plurality of push switches. The switch control wheel includes a plurality of wheel-shaped structures stacked sequentially, wherein each of the wheel-shaped structures has at least one notch formed on an outer periphery of the switch control wheel, and the diameters of the wheel-shaped structures reduce sequentially so that the switch control wheel is in tapered shape. The driving assembly drives the switch control wheel to rotate. The push switches are switched by engaging into or separating from the notches of the wheel-shaped structures as the switch control wheel rotated by the driving assembly. Since the switch control wheel is in a tapered shape, so that the switch control wheel is easily to be formed monolithically and is convenient to be installed to the case of the automatic timing switch device.
摘要翻译：自动定时开关装置包括开关控制轮，驱动组件和多个按压开关。开关控制轮包括依次堆叠的多个轮形结构，其中每个轮形结构具有形成在开关控制轮的外周上的至少一个切口，并且轮形结构的直径依次减小使开关控制轮呈锥形。驱动组件驱动开关控制轮旋转。当由驱动组件旋转的开关控制轮时，按钮开关通过与轮形结构的凹口接合或分离而被切换。由于开关控制轮是锥形的，所以开关控制轮容易被单块地形成，并且便于安装到自动定时开关装置的情况。

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