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81. 发明授权

US06168001A Positive drive coin discrimination apparatus and method 失效
标题翻译：正驱动硬币识别装置和方法
公开(公告)号：US06168001A
公开(公告)日：2001-01-02
申请号：US08883655
申请日：1997-06-27
申请人： David Lawrence Davis
发明人： David Lawrence Davis
IPC分类号： G07D508
CPC分类号： G07D3/14 , G07D9/008
摘要： A coin discrimination device which provides for positive transport of coins past a sensor is provided. In one embodiment, a rotating disk, slightly inclined to the vertical, includes a plurality of pockets for receiving coins from a hopper bowl. The disk and bowl are configured to efficiently load the pockets with no more than one coin per pocket. As the disk rotates, the coins, which are thus registered in a desired location in the pockets, are transported by the rotating disk past a sensor. When, based on the sensor data, the item in a pocket is recognized as an acceptable coin, a controllable ramp is lowered to divert the coin out of the pocket and into a path to place the coin in an acceptance bin or bag.
摘要翻译：提供一种硬币识别装置，其提供硬币通过传感器的正向传送。在一个实施例中，与垂直方向稍微倾斜的旋转盘包括多个用于从料斗碗容纳硬币的袋。盘和碗被配置为有效地装载袋，每个口袋不超过一个硬币。当盘旋转时，由此登记在口袋中的期望位置的硬币通过旋转盘传送通过传感器。当基于传感器数据将口袋中的物品识别为可接受的硬币时，降低可控的斜坡以将硬币从口袋转出并转移到将硬币放置在接收箱或袋中的路径中。

82. 发明授权

US6092119A Random access audio/video processor with compressed video resampling to allow higher bandwidth throughput 失效
标题翻译：随机访问音频/视频处理器，具有压缩视频重新采样以允许更高的带宽吞吐量
公开(公告)号：US6092119A
公开(公告)日：2000-07-18
申请号：US876780
申请日：1997-06-16
申请人： David Lawrence Rossmere , Robert Samuel Glenn, Jr. , William Blake Brown , John Bryan Carluci , Robert William Duffy
发明人： David Lawrence Rossmere , Robert Samuel Glenn, Jr. , William Blake Brown , John Bryan Carluci , Robert William Duffy
IPC分类号： G06T3/00 , G11B20/10 , G11B27/032 , G11B27/034 , G11B27/34 , H04N5/262 , H04N5/91 , G06F13/00
CPC分类号： H04N5/262 , G11B27/032 , G11B27/034 , G11B27/34 , G11B2220/20 , G11B2220/90
摘要： A random access audio/video processor having multiple outputs is disclosed. The processor includes a main control unit with analog video and audio back panels, an analog input/output board, audio and video processing boards, video effects board, synchronization board, and a system board (containing the main CPU). The video processing board includes a compressor for compressing input video signals, and triple transfer buffers for intermediate storage of digital video path. The video processing board further includes decompression circuits coupled to each of two triple transfer buffers for decompressing compressed stored video, and providing the decompressed video channels to an effects board for the addition of special effects. The audio processing board contains processors for compression, decompression, and effects, as well as triple transfer buffers. The triple transfer buffers include present, past, and future buffers which jointly operate to minimize discontinuities in the output channels. The invention provides an E to C mode to allow the user to preview video which has been compressed and decompressed to verify that no unwanted system artifacts exist, or are created by the compression process. This previewing is done in real-time while the material is being compressed and stored. A user may also bypass the compression circuit and capture uncompressed still frames directly in the triple transfer buffer, and store the uncompressed still frames, thereby permitting the independent display of still and motion video in each output channel.
摘要翻译：公开了具有多个输出的随机存取音频/视频处理器。处理器包括具有模拟视频和音频后面板的主控制单元，模拟输入/输出板，音频和视频处理板，视频效果板，同步板和系统板（包含主CPU）。视频处理板包括用于压缩输入视频信号的压缩器和用于数字视频路径的中间存储的三重传送缓冲器。视频处理板还包括耦合到两个三重传输缓冲器中的每一个的解压缩电路，用于对压缩存储的视频进行解压缩，以及将解压缩的视频通道提供给效果板以增加特殊效果。音频处理板包含用于压缩，解压缩和效果的处理器，以及三重传输缓冲器。三重传输缓冲器包括联合操作以使输出通道中的不连续性最小化的当前，过去和将来的缓冲器。本发明提供了一种E到C模式，以允许用户预览已被压缩和解压缩的视频，以验证是否存在不需要的系统工件，或者由压缩处理创建。这种预览是在材料被压缩和存储的时候实时完成的。用户还可以绕过压缩电路并且在三重传送缓冲器中直接捕获未压缩的静止帧，并存储未压缩的静止帧，从而允许在每个输出通道中独立地显示静止和运动的视频。

83. 发明授权

US6083924A DnaB of staphylococcus aureus 失效
标题翻译： DnaB金黄色葡萄球菌
公开(公告)号：US6083924A
公开(公告)日：2000-07-04
申请号：US38909
申请日：1998-03-12
申请人： David Lawrence Earnshaw , Earl William May , Damien McDevitt
发明人： David Lawrence Earnshaw , Earl William May , Damien McDevitt
IPC分类号： C12N15/09 , A61K31/711 , A61K38/00 , A61K39/00 , A61K45/00 , A61K48/00 , A61P31/00 , A61P43/00 , C07K14/315 , C07K16/14 , C12N1/21 , C12N9/90 , C12N15/31 , C12Q1/68 , G06F17/30 , C07H21/00 , C12N15/63
CPC分类号： C12N9/90 , C12Y599/01003 , A61K38/00 , A61K39/00
摘要： The invention provides dnaB polypeptides and polynucleotides encoding dnaB polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing dnaB polypeptides to screen for antibacterial compounds.
摘要翻译：本发明提供了dnaB多肽和编码dnaB多肽的多核苷酸以及通过重组技术产生这种多肽的方法。还提供了利用dnaB多肽筛选抗菌化合物的方法。

84. 发明授权

US5958732A Platelet aggregation inhibitors 失效
标题翻译：血小板聚集抑制剂
公开(公告)号：US5958732A
公开(公告)日：1999-09-28
申请号：US474249
申请日：1995-06-07
申请人： Robert M. Scarborough , David Lawrence Wolf , Israel F. Charo
发明人： Robert M. Scarborough , David Lawrence Wolf , Israel F. Charo
IPC分类号： A61K38/00 , A61K35/58 , A61K38/02 , A61K38/12 , A61K38/17 , A61K38/36 , A61K38/57 , A61P7/02 , C07K1/14 , C07K1/20 , C07K7/00 , C07K7/06 , C07K7/64 , C07K14/00 , C07K14/435 , C07K14/46 , C07K14/745 , C07K14/75 , C07K14/755 , C07K14/78 , C12N1/21 , C12N15/09 , C12N15/12 , C12P21/00 , C12P21/02 , C12Q1/56 , C12R1/19 , G01N33/86 , C12P21/06 , C07K17/00 , C12N5/00 , C12N15/00
CPC分类号： C07K14/75 , A61K38/12 , A61K38/1703 , A61K38/57 , C07K14/46 , C07K14/755 , C07K14/78
摘要： An assay for screening snake venom for the presence or absence of platelet aggregation inhibitors (PAIs) based on specific receptor binding is described. Using this assay, the identification and characterization of PAIs in a wide range of snake venom samples was accomplished. The isolated and purified PAI from several of these active snake venoms is described and characterized. In addition, PAIs lacking the Arg-Gly-Asp (RGD) adhesion sequence but containing K* -(G/Sar)-D wherein K* is a modified lysyl residue of the formulaR.sup.1.sub.2 N(CH.sub.2).sub.4 CHNHCO--wherein each R.sup.1 is independently H, alkyl(1-6C) or at most one R.sup.1 is R.sup.2 --C.dbd.NR.sup.3 wherein R.sup.2 is H, alkyl(1-6C) or is NR.sup.4.sub.2 in which each R.sup.4 is independently H or alkyl(1-6C) and R.sup.3 is H, alkyl(1-6C), phenyl or benzyl, or R.sup.2 --C.dbd.NR.sup.3 is a radical selected from the group consisting of: ##STR1## where m is an integer of 2-3, and each R.sup.5 is independently H or alkyl(1-6C);and wherein one or two (CH.sub.2) may be replaced by O or S provided said O or S is not adjacent to another heteroatomare prepared and shown to specifically inhibit the binding of fibrinogen or von Willebrand Factor to GP IIb-IIIa.
摘要翻译：描述了基于特异性受体结合筛选蛇毒用于存在或不存在血小板聚集抑制剂（PAI）的测定法。使用该测定，完成了广泛的蛇毒样品中PAIs的鉴定和表征。描述和表征了来自这些活性蛇毒中的几种的分离和纯化的PAI。另外，缺乏Arg-Gly-Asp（RGD）粘附序列但含有K * - （G / Sar）-D的PAI，其中K *是式R 12 N（CH 2）4 CHNHCO-的修饰的赖氨酰残基，其中每个R 1独立地为H ，烷基（1-6C）或至多一个R1是R2-C = NR3，其中R2是H，（1-6C）烷基或NR42，其中每个R4独立地是H或烷基（1-6C），R3是H ，（1-6C）烷基，苯基或苄基，或R2-C = NR3是选自下组的基团：其中m是2-3的整数，并且每个R 5独立地是H或烷基（1-6C ）; 并且其中一个或两个（CH 2）可以被O或S替代，条件是所述O或S不与另一个杂原子相邻，并且显示出特异性抑制纤维蛋白原或血管性血友病因子与GP IIb-IIIa的结合。

85. 发明授权

US5922748A Indole derivatives as 5-HT agonists 失效
标题翻译：吲哚衍生物作为5-HT激动剂
公开(公告)号：US5922748A
公开(公告)日：1999-07-13
申请号：US8833
申请日：1998-01-20
申请人： Robert Charles Glen , David Lawrence Selwood , Graeme Richard Martin , Christopher James Foster
发明人： Robert Charles Glen , David Lawrence Selwood , Graeme Richard Martin , Christopher James Foster
IPC分类号： C07D401/04 , A61K31/40 , A61K31/403 , A61K31/4035 , A61K31/404 , A61K31/405 , A61K31/41 , A61K31/415 , A61K31/42 , A61P25/04 , A61P25/06 , A61P43/00 , C07D209/14 , C07D209/48 , C07D209/54 , C07D401/06 , C07D403/04 , C07D403/06 , C07D413/04 , C07D413/06
CPC分类号： C07D209/48 , C07D209/14 , C07D401/06 , C07D403/06 , C07D413/04 , C07D413/06
摘要： Compounds of formula (I) ##STR1## wherein R and R.sup.1 are hydrogen, C.sub.1-4 alkyl or are linked to form a ring,A is a cycloalkyl or alkyl-cycloalkyl group,n is an integer from 0 to 3,W is an optionally substituted 5-or 6-membered heterocyclic ring; or W is an optionally substituted aryl, heteroaryl, aryloxy or thiophenoxy group; orW is a group --SO.sub.2 NR.sup.6 R.sup.7 --NHC(O)R.sup.6 R.sup.7 or --C(O)NHR.sup.6 R.sup.7 ; are useful in treating clinical conditions for which a "5-HT.sub.1 -like" receptor agonist is indicated.
摘要翻译：式（I）化合物，其中R和R 1是氢，C 1-4烷基或连接形成环，A是环烷基或烷基 - 环烷基，n是0-3的整数，W是任选取代的5 - 或6-元杂环; 或W是任选取代的芳基，杂芳基，芳氧基或硫代苯氧基; 或W是基团-SO 2 NR 6 R 7 -NHC（O）R 6 R 7或-C（O）NHR 6 R 7; 可用于治疗表现为“5-HT1样”受体激动剂的临床病症。

86. 发明授权

US5843897A Platelet aggregation inhibitors 失效
标题翻译：血小板聚集抑制剂
公开(公告)号：US5843897A
公开(公告)日：1998-12-01
申请号：US462678
申请日：1995-06-05
申请人： Robert M. Scarborough , David Lawrence Wolf , Israel F. Charo
发明人： Robert M. Scarborough , David Lawrence Wolf , Israel F. Charo
IPC分类号： A61K38/00 , A61K38/12 , A61K38/17 , A61K38/57 , C07K14/46 , C07K14/75 , C07K14/755 , C07K14/78 , A61K38/02 , C07K5/00 , C07K7/00
CPC分类号： A61K38/12 , A61K38/1703 , A61K38/57 , C07K14/46 , C07K14/75 , C07K14/755 , C07K14/78
摘要： An assay for screening snake venom for the presence or absence of platelet aggregation inhibitors (PAIs) based on specific receptor binding is described. Using this assay, the identification and characterization of PAIs in a wide range of snake venom samples was accomplished. The isolated and purified PAI from several of these active snake venoms is described and characterized. In addition, PAIs lacking the Arg-Gly-Asp (RGD) adhesion sequence but containing K.sup.* -(G/Sar)-D wherein K.sup.* is a modified lysyl residue of the formula R.sup.1.sub.2 N(CH.sub.2).sub.4 CHNHCO-- wherein each R.sup.1 is independently H, alkyl(1-6C) or at most one R.sup.1 is R.sup.2 --C.dbd.NR.sup.3 wherein R.sup.2 is H, alkyl(1-6C), phenyl or benzyl, or is NR.sup.4.sub.2 in which each R.sup.4 is independently H or alkyl(1-6C) and R.sup.3 is H, alkyl(1-6C), phenyl or benzyl, or R.sup.2 --C.dbd.NR.sup.3 is a radical selected from the group consisting of: ##STR1## where m is an integer of 2-3, and each R is independently H or alkyl(1-6C); and wherein one or two (CH.sub.2) may be replaced by O or S provided said O or S is not adjacent to another heteroatom are prepared and shown to specifically inhibit the binding of fibrinogen or von Willebrand Factor to GP IIb-IIIa.
摘要翻译：描述了基于特异性受体结合筛选蛇毒用于存在或不存在血小板聚集抑制剂（PAI）的测定法。使用该测定，完成了广泛的蛇毒样品中PAIs的鉴定和表征。描述和表征了来自这些活性蛇毒中的几种的分离和纯化的PAI。另外，缺少Arg-Gly-Asp（RGD）粘附序列但含有K * - （G / Sar）-D的PAI，其中K *是式R12N（CH2）4CHNHCO-的修饰的赖氨酰残基，其中每个R 1独立地 H，烷基（1-6C）或至多一个R1是R2-C = NR3，其中R2是H，烷基（1-6C），苯基或苄基，或是NR42，其中每个R4独立地是H或烷基（1- 6C），R3是H，（1-6C）烷基，苯基或苄基，或R2-C = NR3是选自以下的基团：其中m是2-3的整数，并且每个R 独立地是H或（1-6C）烷基; 并且其中一个或两个（CH 2）可以被O或S替代，条件是所述O或S不与另一个杂原子相邻，并且显示出特异性抑制纤维蛋白原或血管性血友病因子与GP IIb-IIIa的结合。

87. 发明授权

US5767698A High speed differential output driver with common reference 失效
标题翻译：高速差分输出驱动器，具有通用参考
公开(公告)号：US5767698A
公开(公告)日：1998-06-16
申请号：US659293
申请日：1996-06-06
申请人： Roger Dale Emeigh , James Francis Mikos , David Lawrence Pease , James David Strom
发明人： Roger Dale Emeigh , James Francis Mikos , David Lawrence Pease , James David Strom
IPC分类号： H03K19/003 , H03K19/0175 , H04L25/02 , H03K19/094
CPC分类号： H03K19/017545 , H03K19/00369
摘要： A plurality of high speed differential output drivers are coupled to a reference current generator such that each output driver receives a substantially identical copy of a reference current signal for controlling one or more operational parameters (e.g., the propagation delay or skew) of the output driver. Multiple copies of the reference current signal are generated within the same region of an integrated circuit chip, thereby minimizing any process variations within the chip that might cause variances between the individual copies of the reference current signal. Each differential output driver has a differential pair of transistors that are coupled to ground or supply voltage through a common mode resistor that controls the common mode component of the driver output independent of the voltage swing of the output.
摘要翻译：多个高速差分输出驱动器耦合到参考电流发生器，使得每个输出驱动器接收参考电流信号的基本相同的副本，用于控制输出驱动器的一个或多个操作参数（例如，传播延迟或偏斜）。参考电流信号的多个副本在集成电路芯片的相同区域内产生，从而最小化可能导致参考电流信号的各个副本之间的变化的芯片内的任何过程变化。每个差分输出驱动器具有通过共模电阻器耦合到接地或供电电压的差分对晶体管，其独立于输出的电压摆幅来控制驱动器输出的共模分量。

88. 发明授权

US5754178A Method and apparatus for improved feedback during manipulation of data on a computer controlled display system 失效
标题翻译：用于在计算机控制的显示系统上操纵数据期间改进反馈的方法和装置
公开(公告)号：US5754178A
公开(公告)日：1998-05-19
申请号：US543699
申请日：1995-10-16
申请人： Robert George Johnston, Jr. , David Lawrence Evans , David H. Owens , Nick G. Kledzik , Mark Ludwig Stern , Herman Jesus Camarena , Bruce Bartholomew Gaya , John R. Meier , Stephen Fisher , Eric Mathew Trehus
发明人： Robert George Johnston, Jr. , David Lawrence Evans , David H. Owens , Nick G. Kledzik , Mark Ludwig Stern , Herman Jesus Camarena , Bruce Bartholomew Gaya , John R. Meier , Stephen Fisher , Eric Mathew Trehus
IPC分类号： G06F3/0486 , G06F9/44 , G06F3/14
CPC分类号： G06F3/0486 , G06F9/4443
摘要： A method and apparatus for improved user interaction and feedback on a computer system display. Interapplication dragging upon a user interface display is provided allowing a user to select a first item in a first window and move that first item to a second window which is under control of second process. Feedback is provided in the second window under control of the second process if the second application program can accept the data. In addition, other improved user interface actions are described, such as improved selection feedback, improved navigation, and improved completion feedback.
摘要翻译：一种用于在计算机系统显示器上改进用户交互和反馈的方法和装置。提供在用户界面显示上拖动的应用，允许用户在第一窗口中选择第一项，并将该第一项移动到第二个进程控制的第二个窗口。如果第二个应用程序可以接受数据，则在第二个窗口的控制下提供反馈。此外，还描述了其他改进的用户界面动作，例如改进的选择反馈，改进的导航和改进的完成反馈。

89. 发明授权

US5736339A Method utilizing purified GP IIb-IIIa to detect the presence of platelet aggregation inhibitors 失效
标题翻译：使用纯化的GP IIb-IIIa检测血小板聚集抑制剂的存在的方法
公开(公告)号：US5736339A
公开(公告)日：1998-04-07
申请号：US463986
申请日：1995-06-05
申请人： Robert M. Scarborough , David Lawrence Wolf , Israel F. Charo
发明人： Robert M. Scarborough , David Lawrence Wolf , Israel F. Charo
IPC分类号： A61K38/00 , A61K35/58 , A61K38/02 , A61K38/12 , A61K38/17 , A61K38/36 , A61K38/57 , A61P7/02 , C07K1/14 , C07K1/20 , C07K7/00 , C07K7/06 , C07K7/64 , C07K14/00 , C07K14/435 , C07K14/46 , C07K14/745 , C07K14/75 , C07K14/755 , C07K14/78 , C12N1/21 , C12N15/09 , C12N15/12 , C12P21/00 , C12P21/02 , C12Q1/56 , C12R1/19 , G01N33/86 , G01N33/68
CPC分类号： C07K14/75 , A61K38/12 , A61K38/1703 , A61K38/57 , C07K14/46 , C07K14/755 , C07K14/78
摘要： An assay for screening snake venom for the presence or absence of platelet aggregation inhibitors (PAIs) based on specific receptor binding is described. Using this assay, the identification and characterization of PAIs in a wide range of snake venom samples was accomplished. The isolated and purified PAI from several of these active snake venoms is described and characterized. In addition, PAIs lacking the Arg-Gly-Asp (RGD) adhesion sequence but containing K*-(G/Sar)-D wherein K* is a modified lysyl residue of the formula R.sup.1.sub.2 N(CH.sub.2).sub.4 CHNHCO-- wherein each R.sup.1 is independently H, alkyl(1-6C) or at most one R.sup.1 is R.sup.2 --C.dbd.NR.sup.3 wherein R.sup.2 is H, alkyl(1-6C) or is NR.sup.4.sub.2 in which each R.sup.4 is independently H or alkyl(1-6C) and R.sup.3 is H, alkyl(1-6C), phenyl or benzyl, or R.sub.2 --C.dbd.NR.sup.3 is a radical selected from the group consisting of: ##STR1## where m is an integer of 2-3, and each R.sup.5 is independently H or alkyl(1-6C); and wherein one or two (CH.sub.2) may be replaced by O or S provided said O or S is not adjacent to another heteroatom are prepared and shown to specifically inhibit the binding of fibrinogen or yon Willebrand Factor to GP IIb-IIIa.
摘要翻译：描述了基于特异性受体结合筛选蛇毒用于存在或不存在血小板聚集抑制剂（PAI）的测定法。使用该测定，完成了广泛的蛇毒样品中PAIs的鉴定和表征。描述和表征了来自这些活性蛇毒中的几种的分离和纯化的PAI。另外，缺少Arg-Gly-Asp（RGD）粘附序列但含有K * - （G / Sar）-D的PAI，其中K *是式R12N（CH2）4CHNHCO-的修饰的赖氨酰残基，其中每个R 1是独立地是H，烷基（1-6C）或至多一个R 1是R 2 -C = NR 3，其中R 2是H，烷基（1-6C）或NR 42，其中每个R 4独立地是H或烷基（1-6C）和R 3 是H，烷基（1-6C），苯基或苄基，或R2-C = NR3是选自以下的基团：其中m是2-3的整数，并且每个R 5是独立地是H或（1-6C）烷基; 并且其中一个或两个（CH 2）可以被O或S替代，条件是所述O或S不与另一个杂原子相邻，并且显示出特异性抑制纤维蛋白原或YE Willebrand因子与GP IIb-IIIa的结合。

90. 发明授权

US5686568A Platelet aggregration inhibitors 失效
标题翻译：血小板聚集抑制剂
公开(公告)号：US5686568A
公开(公告)日：1997-11-11
申请号：US463985
申请日：1995-06-05
申请人： Robert M. Scarborough , David Lawrence Wolf , Israel F. Charo
发明人： Robert M. Scarborough , David Lawrence Wolf , Israel F. Charo
IPC分类号： A61K38/00 , A61K38/12 , A61K38/17 , A61K38/57 , C07K14/46 , C07K14/75 , C07K14/755 , C07K14/78 , C07K5/00 , C07K7/00
CPC分类号： A61K38/12 , A61K38/1703 , A61K38/57 , C07K14/46 , C07K14/75 , C07K14/755 , C07K14/78
摘要： An assay for screening snake venom for the presence or absence of platelet aggregation inhibitors (PAIs) based on specific receptor binding is described. Using this assay, the identification and characterization of PAIs in a wide range of snake venom samples was accomplished. The isolated and purified PAI from several of these active snake venoms is described and characterized. In addition, PAIs lacking the Arg-Gly-Asp (RGD) adhesion sequence but containing K*-(G/Sar)-D wherein K* is a modified lysyl residue of the formula R.sup.1.sub.2 N(CH.sub.2).sub.4 CHNHCO-- wherein each R.sup.1 is independently H, alkyl(1-6C) or at most one R.sup.1 is R.sup.2 --C.dbd.NR.sup.3 wherein R.sup.2 is H, alkyl(1-6C), phenyl or benzyl, or is NR.sup.4.sub.2 in which each R.sup.4 is independently H or alkyl(1-6C) and R.sup.3 is H, alkyl(1-6C), phenyl or benzyl, or R.sup.2 --C.dbd.NR.sup.3 is a radical selected from the group consisting of: ##STR1## where m is an integer of 2-3, and each R.sup.5 is independently H or alkyl(1-6C); and wherein one or two (CH.sub.2) may be replaced by O or S provided said O or S is not adjacent to another heteroatom are prepared and shown to specifically inhibit the binding of fibrinogen or von Willebrand Factor to GP IIb-IIIa.
摘要翻译：描述了基于特异性受体结合筛选蛇毒用于存在或不存在血小板聚集抑制剂（PAI）的测定法。使用该测定，完成了广泛的蛇毒样品中PAIs的鉴定和表征。描述和表征了来自这些活性蛇毒中的几种的分离和纯化的PAI。另外，缺乏Arg-Gly-Asp（RGD）粘附序列但含有K * - （G / Sar）-D的PAI，其中K *是式R 12 N（CH 2）4 CHNHCO-的修饰的赖氨酰残基，其中每个R 1独立地为H ，烷基（1-6C）或至多一个R1是R2-C = NR3，其中R2是H，烷基（1-6C），苯基或苄基，或是NR42，其中每个R4独立地是H或烷基（1-6C ）和R 3是H，烷基（1-6C），苯基或苄基，或者R 2 -C = NR 3是选自下列的基团：依赖性地是H或烷基（1-6C）; 并且其中一个或两个（CH 2）可以被O或S替代，条件是所述O或S不与另一个杂原子相邻，并且显示出特异性抑制纤维蛋白原或血管性血友病因子与GP IIb-IIIa的结合。

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