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81. 发明授权

US4052367A Radiation sensitive polymers of oxygen-substituted maleimides and elements containing same 失效
标题翻译：含氧取代的氧化物和含有它们的元素的辐射敏感聚合物
公开(公告)号：US4052367A
公开(公告)日：1977-10-04
申请号：US621728
申请日：1975-10-14
申请人： John Charles Wilson
发明人： John Charles Wilson
IPC分类号： C08F34/00 , G03F7/032 , C08F26/06
CPC分类号： C08F34/00 , G03F7/032 , Y10S522/904 , Y10T428/31855
摘要： Radiation sensitive polymers comprising:A. from about 1 to 100 mole percent of a polymerized monomer having the formula ##STR1## wherein R is a hydrocarbon group having from 2 to 20 carbon atoms, preferably a bridged hydrocarbon group having from 6 to 10 carbon atoms; andB. from 0 to about 99 mole percent of at least one additional polymerized ethylenically unsaturated monomer are advantageously soluble in organic solvents, possess desirably high glass transition temperatures and are capable of undergoing a photochemical reaction to yield polymers having isocyanate and oxy-substituted cyclopropane moieties which are capable of crosslinking in the presence of active hydrogen-containing compounds. The polymers are useful in radiation sensitive compositions and elements containing same.

82. 发明授权

US2197599A Sewing machine 失效
公开(公告)号：US2197599A
公开(公告)日：1940-04-16
申请号：US20747538
申请日：1938-05-12
申请人： CHARLES WILSON FOREST
发明人： CHARLES WILSON FOREST
IPC分类号： D05B77/00
CPC分类号： D05B77/00

83. 发明授权

US10315348B2 Completely disposable cooking apparatus for filling and decorating of foods 有权
公开(公告)号：US10315348B2
公开(公告)日：2019-06-11
申请号：US15804801
申请日：2017-11-06
申请人： Brenda Marie Grimes , Charles Wilson Grimes
发明人： Brenda Marie Grimes , Charles Wilson Grimes
IPC分类号： B29C47/04 , B29C47/12 , A23G3/28 , A47J47/01 , A21C15/00 , B29C47/00 , A47G19/34 , A47G19/32
摘要： A cooking apparatus used for filling and decorating of foods, comprising in some embodiments a one-piece, funnel-shaped bag with a soft side wall, having an open first end at the “top” through which food material and coloring agents can be inserted into the bag and a closed second end at the “bottom” end of the funnel, with an integral, malleable, conical shaped, discharge orifice. The orifice may have serrations or ridges extending inwardly from the internal wall of the orifice, running longitudinally or parallel to the cone axis. The orifice may be initially closed or manufactured with a small opening. The orifice may be made of a material capable of being cut to yield an exit opening. The inwardly extending serrations that remain after a cut may insure that the material is “treated” as it is expelled from the bag through the orifice to yield a ribbon candy design.

84. 发明授权

US09704276B1 Enhancement and display methods for intuitively read three-dimensional visual representations of digital audio files 有权
公开(公告)号：US09704276B1
公开(公告)日：2017-07-11
申请号：US14451811
申请日：2014-08-05
申请人： Randall Charles Wilson
发明人： Randall Charles Wilson
IPC分类号： G06T17/00 , G06T11/20 , G10L19/02 , G06F3/0484
CPC分类号： G06T11/206 , G06F3/04847 , G06F2203/04802 , G06T17/00 , G06T2207/20108 , G10H1/0008 , G10H2220/005 , G10H2220/131 , G10H2250/235 , G10L21/10 , G11B27/34
摘要： The proposed method creates a detailed, accurate, frequency and amplitude-based three-dimensional moving display of digital audio files. It adds timestamps, used later in the process to achieve accurate synchronization between a moving display and playback of the analyzed audio file. It details how the analyzed data is processed and enhanced to prominently show the most fundamental elements in the audio file. The method proposes different layouts for displays and ways of showing separate elements of the audio simultaneously. Upcoming audio is displayed in locations that allow viewers to anticipate and react to events about to happen. It introduces the temporal plane of playback for clearly showing the part of the moving display that corresponds to the exact part of the analyzed audio that is playing. The temporal plane of playback demonstrates the direct correlation with the audio and accurate synchronization between sound and picture.

85. 发明授权

US08853376B2 Stabilized aptamers to platelet derived growth factor and their use as oncology therapeutics 有权
标题翻译：稳定的适体与血小板衍生生长因子及其作为肿瘤学治疗的用途
公开(公告)号：US08853376B2
公开(公告)日：2014-10-07
申请号：US13235222
申请日：2011-09-16
申请人： Dilara McCauley , John L. Diener , Charles Wilson , Thomas Greene McCauley
发明人： Dilara McCauley , John L. Diener , Charles Wilson , Thomas Greene McCauley
IPC分类号： C07H21/02 , C07H21/04
CPC分类号： C12N15/115 , A61K31/4745 , A61K31/7088 , A61K45/06 , A61K47/60 , C12N2310/16 , C12N2310/335 , C12N2310/351 , C12N2310/353 , C12N2320/30 , C12N2320/31
摘要： Materials and methods are provided for producing and using aptamers useful as oncology therapeutics capable of binding to PDGF, PDGF isoforms, PDGF receptor, VEGF, and VEGF receptor or any combination thereof with great affinity and specificity. The compositions of the present invention are particularly useful in solid tumor therapy and can be used alone or in combination with known cytotoxic agents for the treatment of solid tumors. Also disclosed are aptamers having one or more CpG motifs embedded therein or appended thereto.
摘要翻译：提供材料和方法用于生产和使用适合于能够以极大的亲和力和特异性结合PDGF，PDGF同种型，PDGF受体，VEGF和VEGF受体或其任何组合的肿瘤学治疗剂的适体。本发明的组合物特别可用于实体瘤治疗，并且可以单独使用或与已知的细胞毒剂组合用于治疗实体瘤。还公开了具有一个或多个CpG基序嵌入其中或附着于其上的适体。

86. 发明申请

US20130287910A1 COMPLETELY DISPOSABLE COOKING APPARATUS FOR FILLING AND DECORATING OF FOODS 审中-公开
标题翻译：完全可食用的烹饪设备，用于食物的装饰和装饰
公开(公告)号：US20130287910A1
公开(公告)日：2013-10-31
申请号：US13852507
申请日：2013-03-28
申请人： Brenda Marie Grimes , Charles Wilson Grimes
发明人： Brenda Marie Grimes , Charles Wilson Grimes
IPC分类号： B29C47/04
CPC分类号： B29C47/046 , A21C15/005 , A23G3/28 , A47G19/32 , A47G19/34 , A47J47/01 , B29C47/0023 , B29C47/003 , B29C47/0033 , B29C47/12
摘要： A cooking apparatus used for filling and decorating of foods, comprising in some embodiments a one-piece, funnel-shaped bag with a soft side wall, having an open first end at the “top” through which food material and coloring agents can be inserted into the bag and a closed second end at the “bottom” end of the funnel, with an integral, malleable, conical shaped, discharge orifice. The orifice may have serrations or ridges extending inwardly from the internal wall of the orifice, running longitudinally or parallel to the cone axis. The orifice may be initially closed or manufactured with a small opening. The orifice may be made of a material capable of being cut to yield an exit opening. The inwardly extending serrations that remain after a cut may insure that the material is “treated” as it is expelled from the bag through the orifice to yield a ribbon candy design.
摘要翻译：一种烹饪装置，用于食品的装饰和装饰，在一些实施方案中，包括具有软侧壁的单件式漏斗形袋，在“顶部”处具有敞开的第一端，通过该第一端可以插入食物和着色剂并且在漏斗的“底部”端处有封闭的第二端，具有整体的，可延展的圆锥形的排出孔。孔可以具有从孔的内壁向内延伸的锯齿或脊，纵向或平行于锥体轴线延伸。孔可以最初关闭或用小开口制造。孔可以由能够被切割以产生出口的材料制成。在切割后保留的向内延伸的锯齿可以确保在通过孔从袋中排出材料时“处理”材料以产生带状糖果设计。

87. 发明申请

US20130153396A1 Purification of a fluid for example water after fracturing 审中-公开
$Purification of a fluid for example water after fracturing$
标题翻译：压裂后液体例如水的净化
公开(公告)号：US20130153396A1
公开(公告)日：2013-06-20
申请号：US13326990
申请日：2011-12-15
申请人： Charles Wilson
发明人： Charles Wilson
IPC分类号： B01D3/10
CPC分类号： B01D21/2461 , B01D1/222 , B01D5/006 , B01D2221/04 , C02F1/048
摘要： An apparatus for treating frac water may include a vacuum container to support a vacuum, a heating device to heat the vacuum container, a spiral auger to rotate to separate the frac water being positioned within the vacuum container, a condenser to condense the water vapor to liquid water, a second vacuum chamber to receive the liquid water and a storage container to store the liquid water.
摘要翻译：用于处理压裂水的装置可以包括用于支撑真空的真空容器，用于加热真空容器的加热装置，旋转螺旋钻以分离位于真空容器内的压裂水，冷凝器将水蒸汽冷凝至液体水，第二真空室以接收液态水和存储容器以储存液态水。

88. 发明申请

US20130113259A1 ADJUSTMENT MECHANISM 审中-公开
标题翻译：调整机制
公开(公告)号：US20130113259A1
公开(公告)日：2013-05-09
申请号：US13810190
申请日：2011-07-08
申请人： Charles Wilson
发明人： Charles Wilson
IPC分类号： A47C7/40 , A47C7/54
CPC分类号： A47C7/40 , A47C7/54 , A47C17/12
摘要： An adjustment mechanism (20) for an article of furniture includes a support structure (22) securable to a seat base of the article of furniture. A carrier (24) is displaceably arranged relative to the support structure (22), the carrier (24) being configured to mount a component (12) of the article of furniture. A link assembly (26) interconnects the support structure (22) and the carrier (24). The link assembly (26) comprises at least one linkage mechanism (52) which causes initial, substantially linear motion of the carrier (24) relative to the support structure (22) to become substantially rotary motion as the carrier (24) moves from a first position to a second position relative to the seat base of the article of furniture.
摘要翻译：用于家具的调节机构（20）包括可固定到家具制品的座椅底座的支撑结构（22）。载体（24）相对于支撑结构（22）可置换地布置，载体（24）构造成安装家具制品的部件（12）。连杆组件（26）将支撑结构（22）和载体（24）互连。连杆组件（26）包括至少一个连杆机构（52），当至少一个联动机构（52）从托架（24）移动时，托架（24）相对于支撑结构（22）初始的基本线性运动将变得基本上旋转运动第一位置相对于家具的座椅底座到达第二位置。

89. 发明申请

US20130017291A1 COMPLETELY DISPOSABLE COOKING APPARATUS FOR FILLING AND DECORATING OF FOODS 有权
标题翻译：完全可食用的烹饪设备，用于食物的装饰和装饰
公开(公告)号：US20130017291A1
公开(公告)日：2013-01-17
申请号：US13366863
申请日：2012-02-06
申请人： Brenda Marie Grimes , Charles Wilson Grimes
发明人： Brenda Marie Grimes , Charles Wilson Grimes
IPC分类号： B29C47/12 , B65D35/00
CPC分类号： B29C47/003 , A21C15/005 , A23G3/28 , B29C47/0023 , B29C47/0033 , B29C47/12 , Y10S425/044
摘要： A completely disposable cooking apparatus used for preparing, filling assembling and decorating of foods, that is a one-piece disposable construction, comprising an elongated bag with a soft side wall, an open first end through which food material can be inserted into the bag and a second end that is closed by a tapered discharge orifice (also sometimes referred to as a nozzle or a tip). The orifice has a first end in contact with the second end of the bag and a distal end away from the bag. The cross-sectional area of the orifice at the first end is greater than the cross-sectional area of the orifice at the distal end. The orifice is made of a material so that it is capable of being cut at any point along its longitudinal axis to yield an exit opening or hole with a desired size.
摘要翻译：一种完全一次性的烹饪设备，用于制备，填充食品的组装和装饰，这是一件一次性的一次性构造，包括具有软侧壁的细长袋，开口的第一端，食物可以通过该第一端插入到袋中，第二端由锥形排出口（有时也称为喷嘴或尖端）封闭。孔口具有与袋的第二端接触的第一端和远离袋的远端。第一端处的孔口的横截面积大于远端处孔口的横截面面积。孔由材料制成，使得其能够沿着其纵向轴线的任何点被切割，以产生具有期望尺寸的出口或孔。

90. 发明申请

US20120322860A1 APTAMER THERAPEUTICS USEFUL IN THE TREATMENT OF COMPLEMENT-RELATED DISORDERS 有权
标题翻译： APTAMER治疗有效治疗补充相关疾病
公开(公告)号：US20120322860A1
公开(公告)日：2012-12-20
申请号：US13525680
申请日：2012-06-18
申请人： CLAUDE BENEDICT , DAVID EPSTEIN , CHARLES WILSON , DILARA MCCAULEY , JEFFREY KURZ , MARKUS KURZ , THOMAS GREENE MCCAULEY , JAMES ROTTMAN
发明人： CLAUDE BENEDICT , DAVID EPSTEIN , CHARLES WILSON , DILARA MCCAULEY , JEFFREY KURZ , MARKUS KURZ , THOMAS GREENE MCCAULEY , JAMES ROTTMAN
IPC分类号： A61K31/711 , A61P9/10 , A61P29/00 , A61P37/00 , C07H21/04 , A61P9/00
CPC分类号： C12N15/115 , A61K47/60 , C12N2310/16 , C12N2310/317 , C12N2310/321 , C12N2310/322 , C12N2310/344 , C12N2310/351 , C12N2310/3533 , C12N2310/3521
摘要： The invention provides nucleic acid therapeutics and methods for using these nucleic acid therapeutics in the treatment of complement-related disorders.
摘要翻译：本发明提供了使用这些核酸治疗剂治疗补体相关疾病的核酸治疗剂和方法。

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