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71. 发明授权

US08455927B2 One-transistor pixel array with cascoded column circuit 有权
公开(公告)号：US08455927B2
公开(公告)日：2013-06-04
申请号：US13174215
申请日：2011-06-30
申请人： Keith Fife
发明人： Keith Fife
IPC分类号： H01L29/66
CPC分类号： G01N27/4148 , C12Q1/6869 , G01J1/46 , G01N27/4143 , G01N27/4145 , G01N33/00 , G01R29/26 , H01L27/14609 , H01L27/14632 , H01L27/14643 , H01L29/66 , H01L2924/0002 , H04N5/374 , Y10T436/25875 , H01L2924/00
摘要： To reduce the pixel size to the smallest dimensions and simplest form of operation, a pixel may be formed by using only one ion sensitive field-effect transistor (ISFET). This one-transistor, or 1T, pixel can provide gain by converting the drain current to voltage in the column. Configurable pixels can be created to allow both common source read out as well as source follower read out. A plurality of the 1T pixels may form an array, having a number of rows and a number of columns and a column readout circuit in each column. A cascoded device enabled during readout may be used to provide increased programmable gain.

72. 发明授权

US08432150B2 Methods for operating an array column integrator 有权
标题翻译：操作数组列积分器的方法
公开(公告)号：US08432150B2
公开(公告)日：2013-04-30
申请号：US13421721
申请日：2012-03-15
申请人： Peter Levine
发明人： Peter Levine
IPC分类号： G01R27/00
CPC分类号： G01N27/4148 , C12Q1/6869 , G01J1/46 , G01N27/4143 , G01N27/4145 , G01N33/00 , G01R29/26 , H01L27/14609 , H01L27/14632 , H01L27/14643 , H01L29/66 , H01L2924/0002 , H04N5/374 , Y10T436/25875 , H01L2924/00
摘要： Methods are described for reading a chemically-sensitive field-effect transistor (chemFET) with an improved signal-to-noise ratio. In one embodiment, a method is described for reading a chemFET having a first terminal and a second terminal, and a floating gate coupled to a passivation layer. The method includes biasing the first terminal of the chemFET to a first bias voltage during a read interval. The second terminal of the chemFET is coupled to a data line during the read interval. A current is induced through the chemFET via the data line. An output signal proportional to an integral of a voltage or current on the data line is generated in response to the induced current through the chemFET during the read interval.
摘要翻译：描述了用于读取具有改善的信噪比的化学敏感场效应晶体管（chemFET）的方法。在一个实施例中，描述了一种用于读取具有第一端子和第二端子的chemFET以及耦合到钝化层的浮动栅极的方法。该方法包括在读取间隔期间将chemFET的第一端偏压到第一偏置电压。 chemFET的第二个端子在读取间隔期间耦合到数据线。通过chemFET通过数据线感应出电流。响应于在读取间隔期间通过chemFET的感应电流，产生与数据线上的电压或电流的积分成比例的输出信号。

73. 发明授权

US08398920B2 Drinking vessels and related systems and methods 有权
标题翻译：饮水船及相关系统和方法
公开(公告)号：US08398920B2
公开(公告)日：2013-03-19
申请号：US12462051
申请日：2009-07-28
申请人： Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Clarence T. Tegreene , Lowell L. Wood, Jr. , Victoria Y. H. Wood
发明人： Roderick A. Hyde , Muriel Y. Ishikawa , Jordin T. Kare , Eric C. Leuthardt , Clarence T. Tegreene , Lowell L. Wood, Jr. , Victoria Y. H. Wood
IPC分类号： G01N33/14
CPC分类号： B60W50/0098 , A47G19/2227 , A47G23/0306 , A47G2019/2238 , A47G2019/2244 , B01L2200/16 , B01L2300/042 , G01F23/0061 , G01N33/00 , G01N33/0004 , G01N33/14 , G01N33/146 , G01N33/4972 , G06F17/00 , G06F19/00 , Y10T436/11 , Y10T436/204165
摘要： Embodiments disclosed herein are directed to systems configured to determine an amount of alcohol in an alcohol-containing liquid discharged from a drinking vessel or an amount of the alcohol-containing liquid discharged from the drinking vessel, drinking vessels configured to measure alcohol content or other property of an alcohol-containing liquid held therein, other related components such as mat devices that facilitate determining the amount, and related methods. The systems, drinking vessels, and methods disclosed herein facilitate determination of an amount of alcohol in an alcohol-containing liquid discharged from a drinking vessel or an amount of alcohol-containing liquid discharged from the drinking vessel, which may be indicative of an amount of alcohol consumed by a drinker.
摘要翻译：本文公开的实施例涉及被配置为确定从饮用容器排出的含酒精液体中的醇的量或从饮用容器排出的含酒精液体的量，配置成测量酒精含量或其他性质的饮用容器的含有醇的液体，其他相关组分如便于确定量的垫装置以及相关方法。本文公开的系统，饮用容器和方法有助于确定从饮用容器排出的含酒精液体中的醇的量或从饮用容器排出的含酒精液体的量，其可以指示喝酒者饮酒。

74. 发明申请

US20130066564A1 SYSTEM AND METHOD FOR DYNAMICALLY MEASURING OXYGEN LEVELS 有权
标题翻译：用于动态测量氧气含量的系统和方法
公开(公告)号：US20130066564A1
公开(公告)日：2013-03-14
申请号：US13231661
申请日：2011-09-13
申请人： David E. Forsyth
发明人： David E. Forsyth
IPC分类号： G06F19/00
CPC分类号： G01N21/643 , G01N21/274 , G01N33/00 , G01N2021/6432 , G01N2201/1211 , G01N2201/1218 , G01N2201/126 , G01N2201/127 , G01N2201/12746 , G06F17/40 , G06F19/00
摘要： An oxygen sensing system including an oxygen sensor, a microprocessor and one or more additional sensors for sensing parameters associated with the environment or with the oxygen sensor, accounts for one or more sensed conditions when calculating oxygen levels. The one or more sensors may sense conditions associated with environmental effects or effects of use that may cause the oxygen sensor to degrade over usage or over time. A baseline amplification and measurement circuit coupled to the oxygen sensor may enable the sensor to operate less frequently or for shorter periods of time, thereby increasing the life span, calibration hold time of the sensor, and reducing power requirements.
摘要翻译：包括氧传感器，微处理器和用于感测与环境相关联的参数或氧传感器的一个或多个附加传感器的氧气感测系统在计算氧水平时考虑了一个或多个感测到的状况。一个或多个传感器可以感测与环境影响或使用效果相关的条件，这可能导致氧传感器在使用或时间上降级。耦合到氧传感器的基线放大和测量电路可以使得传感器能够较少频繁地操作或者更短的时间段，由此增加寿命，传感器的校准保持时间和降低功率需求。

75. 发明授权

US08296101B1 Systems and methods for evaluating environmental aspects of shipping systems 有权
标题翻译：用于评估航运系统环境方面的系统和方法
公开(公告)号：US08296101B1
公开(公告)日：2012-10-23
申请号：US12704800
申请日：2010-02-12
申请人： Arnold Barlow , Dennis R. Estep , Andrew J. Gruber , Patrick McDavid , Quinto Marini , Nancy Parmer
发明人： Arnold Barlow , Dennis R. Estep , Andrew J. Gruber , Patrick McDavid , Quinto Marini , Nancy Parmer
IPC分类号： G06F11/30 , G06F19/00 , B65B1/00
CPC分类号： G01N33/00 , G01B21/00 , G01B21/08 , G01N9/36 , G06Q10/08 , G06Q50/28
摘要： According to various embodiments, package evaluation systems and methods are provided for evaluating the sustainability of packaging used in the shipment of goods. In particular, the package evaluation systems and methods are configured for performing package evaluations and managing and providing access to data resulting from package evaluations. The package evaluations are designed to assess, among other things, the ability of sample packages to prevent damage to their contents, the volumetric efficiency of sample packages, and the sustainability of the materials used to construct sample packages. In addition, the systems and methods are further configured for assigning a certification to an entity associated with the evaluated packages based on the results of the evaluation.
摘要翻译：根据各种实施例，提供包装评估系统和方法用于评估用于货物运输的包装的可持续性。特别地，包评估系统和方法被配置为执行包评估并且管理并提供对由包评估产生的数据的访问。包装评估旨在评估样品包装的能力，以防止损坏其内容物，样品包装的体积效率以及用于构建样品包装的材料的可持续性。此外，系统和方法还被配置为基于评估的结果将认证分配给与评估的包相关联的实体。

76. 发明授权

US08294476B2 Method of sensor cell timing 有权
标题翻译：传感器单元定时的方法
公开(公告)号：US08294476B2
公开(公告)日：2012-10-23
申请号：US12815467
申请日：2010-06-15
申请人： Klaus Dimmler , Thomas Moss, III
发明人： Klaus Dimmler , Thomas Moss, III
IPC分类号： G01R27/28
CPC分类号： G01N27/14 , G01N27/414 , G01N27/4148 , G01N33/00 , G01N33/0009
摘要： A method for measuring values from a sensor cell having the basic structure of an MOS silicone transistor having and including a polymer material therein. The method includes the steps of expelling an analyte from the polymer material, determining a silicon current signature before analyte accumulation in a sensitive response region, introducing analyte into the polymer material, determining the silicon current signature immediately after analyte introduction, determining the organic current signature immediately after analyte introduction, allowing analyte accumulation in the polymer material, determining the silicon current signature after analyte accumulation, determining the organic current signature after analyte accumulation, and determining the silicon current signature after analyte accumulation in sensitive response region.
摘要翻译：一种用于测量具有其中具有聚合物材料的MOS硅氧烷晶体管的基本结构的传感器单元的值的方法。该方法包括从聚合物材料排出分析物的步骤，在敏感应答区域中分析物积聚之前确定硅电流特征，将分析物引入聚合物材料中，在分析物引入后立即确定硅电流特征，确定有机电流特征在分析物引入之后，允许分析物在聚合物材料中的积聚，确定分析物堆积后的硅电流特征，确定分析物堆积后的有机电流特征，以及确定敏感响应区域中分析物积累后的硅电流特征。

77. 发明授权

US08273574B2 Apparatus and methods for conducting assays and high throughput screening 有权
标题翻译：用于进行测定和高通量筛选的装置和方法
公开(公告)号：US08273574B2
公开(公告)日：2012-09-25
申请号：US13026587
申请日：2011-02-14
申请人： Stephen R. Quake , Mark A. Unger , Hou-Pu Chou , Todd A. Thorsen , Axel Scherer
发明人： Stephen R. Quake , Mark A. Unger , Hou-Pu Chou , Todd A. Thorsen , Axel Scherer
IPC分类号： G01N15/06 , G01N33/00 , G01N33/48
CPC分类号： G01N33/00 , B01D57/02 , B01D61/18 , B01D61/28 , B01D63/081 , B01D63/088 , B01D2313/08 , B01D2313/90 , B01F5/0646 , B01F5/0647 , B01F7/00 , B01F11/0071 , B01F13/0059 , B01F13/1013 , B01F13/1022 , B01L3/502707 , B01L3/502715 , B01L3/50273 , B01L3/502738 , B01L3/502746 , B01L3/502761 , B01L2200/0631 , B01L2200/10 , B01L2300/0627 , B01L2300/0645 , B01L2300/0681 , B01L2300/0816 , B01L2300/0864 , B01L2300/0867 , B01L2300/0877 , B01L2300/0887 , B01L2300/123 , B01L2300/1822 , B01L2300/1827 , B01L2400/0415 , B01L2400/0481 , B01L2400/0487 , B01L2400/0633 , B01L2400/0655 , B01L2400/082 , C12M23/16 , C12M41/46 , F04B43/043 , F16K99/0001 , F16K99/0009 , F16K99/0015 , F16K99/0046 , F16K99/0048 , F16K99/0051 , F16K99/0059 , F16K2099/0074 , F16K2099/008 , F16K2099/0084 , G01N15/06 , G01N27/44743 , G01N27/44791 , G01N33/5005 , G01N33/5008 , G01N33/56966 , Y10T436/11 , Y10T436/117497 , Y10T436/25 , Y10T436/25375 , Y10T436/2575
摘要： The present invention provides microfluidic devices and methods for using the same. In particular, microfluidic devices of the present invention are useful in conducting a variety of assays and high throughput screening. Microfluidic devices of the present invention include elastomeric components and comprise a main flow channel; a plurality of branch flow channels; a plurality of control channels; and a plurality of valves. Preferably, each of the valves comprises one of the control channels and an elastomeric segment that is deflectable into or retractable from the main or branch flow channel upon which the valve operates in response to an actuation force applied to the control channel.
摘要翻译：本发明提供微流体装置及其使用方法。特别地，本发明的微流体装置可用于进行各种测定和高通量筛选。本发明的微流体装置包括弹性体部件并且包括主流动通道; 多个分支流动通道; 多个控制信道; 和多个阀。优选地，每个阀包括控制通道中的一个和可响应于施加到控制通道的致动力而从阀或液流通道偏转进入或从其中缩回的弹性体段。

78. 发明申请

US20120107937A1 Mitochondrial enhancement of cells 有权
公开(公告)号：US20120107937A1
公开(公告)日：2012-05-03
申请号：US12925849
申请日：2010-10-28
申请人： Roderick A. Hyde , Lowell L. Wood, JR.
发明人： Roderick A. Hyde , Lowell L. Wood, JR.
IPC分类号： C12N15/85 , C12N5/04 , C12N5/10 , C12N5/071
CPC分类号： G06F19/10 , A61K31/713 , G01N33/00 , G06F19/28
摘要： Certain embodiments disclosed herein include, but are not limited to, at least one of compositions, methods, devices, systems, kits, or products regarding rejuvenation or preservation of stem cells. Certain embodiments disclosed herein include, but are not limited to, methods of modifying stem cells, or methods of administering modified stem cells to at least one biological tissue.

79. 发明申请

US20120107285A1 Mitochondrial enhancement of cells 有权
标题翻译：细胞线粒体增强
公开(公告)号：US20120107285A1
公开(公告)日：2012-05-03
申请号：US12925850
申请日：2010-10-28
申请人： Roderick A. Hyde , Lowell L. Wood, JR.
发明人： Roderick A. Hyde , Lowell L. Wood, JR.
IPC分类号： A61K35/12 , G06F19/00 , C12N15/00 , A61P43/00 , C12N5/10 , C40B30/02
CPC分类号： G06F19/10 , A61K31/713 , G01N33/00 , G06F19/28
摘要： Certain embodiments disclosed herein include, but are not limited to, at least one of compositions, methods, devices, systems, kits, or products regarding rejuvenation or preservation of stem cells. Certain embodiments disclosed herein include, but are not limited to, methods of modifying stem cells, or methods of administering modified stem cells to at least one biological tissue.
摘要翻译：本文公开的某些实施方案包括但不限于关于干细胞的再生或保存的组合物，方法，装置，系统，试剂盒或产品中的至少一种。本文公开的某些实施方案包括但不限于修饰干细胞的方法或将修饰的干细胞施用于至少一种生物组织的方法。

80. 发明授权

US08131493B2 Method of automated calibration and diagnosis of laboratory instruments 有权
标题翻译：实验室仪器的自动校准和诊断方法
公开(公告)号：US08131493B2
公开(公告)日：2012-03-06
申请号：US12632742
申请日：2009-12-07
申请人： Bruce De Simas , Leslie Dow
发明人： Bruce De Simas , Leslie Dow
IPC分类号： G06F19/00
CPC分类号： G01N33/00 , G01D18/002 , G01N31/00 , Y10S707/99933 , Y10S707/99942 , Y10T436/10
摘要： Method and system providing an automated workflow for installing and/or calibrating laboratory equipment. The workflow empowers an end user to perform installation and calibration thereby reducing the costs associated with such activities. The automated workflow taught herein, can greatly reduce the incidence of calibration error by providing for verification of certain events during the calibration process.
摘要翻译：提供用于安装和/或校准实验室设备的自动化工作流程的方法和系统。工作流程使最终用户执行安装和校准，从而降低与此类活动相关的成本。本文介绍的自动化工作流可以通过在校准过程中提供某些事件的验证来大大降低校准误差的发生率。

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