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71. 发明申请

US20220007967A1 METHODS AND SYSTEMS FOR DETERMINING COLLATERAL VENTILATION 有权
公开(公告)号：US20220007967A1
公开(公告)日：2022-01-13
申请号：US17363667
申请日：2021-06-30
申请人： Pulmonx Corporation
发明人： Sri Radhakrishnan , Ryan Olivera
IPC分类号： A61B5/091 , A61B5/00
摘要： Methods and systems for determining collateral ventilation are disclosed. Methods may comprise introducing a diagnostic catheter into a lung compartment via an assisted ventilation device, inflating the occluding member to isolate the lung compartment, and performing a diagnostic procedure with the catheter while the patient is ventilated via the assisted ventilation device. The diagnostic procedure comprises determining an exhaled volume from the isolated lung compartment over a predetermined period of time while the patient is ventilated via the assisted ventilation device. The presence collateral ventilation may be determined based on the exhaled volume from the isolated lung compartment over the predetermined period of time.

72. 发明申请

US20210330441A1 IMPLANT LOADING DEVICE AND SYSTEM 有权
公开(公告)号：US20210330441A1
公开(公告)日：2021-10-28
申请号：US17366727
申请日：2021-07-02
申请人： Pulmonx Corporation
发明人： Ryan Olivera , Hoang Nguyen
IPC分类号： A61F2/00 , A61B17/12 , A61F2/04 , A61F2/95 , B65B1/04
摘要： Devices, methods, and systems are provided for loading an implantable device into a container. One aspect of the loading system contains a loader element with a loading tunnel that is configured to gradually contract an implantable device into a compressed state of reduced size relative to an expanded state as the implantable device travels through the loading tunnel.

73. 发明授权

US10932706B2 Methods and systems for endobronchial diagnostics 有权
公开(公告)号：US10932706B2
公开(公告)日：2021-03-02
申请号：US16107849
申请日：2018-08-21
申请人： Pulmonx Corporation
发明人： Surag Mantri , Srikanth Radhakrishnan
IPC分类号： A61B5/1455 , A61B5/08 , A61M16/04 , A61B5/085 , A61B1/00 , A61B1/267 , A61B5/087 , A61B5/145 , A61B5/00 , A61M16/00 , A61B5/091 , A61M16/10
摘要： Methods and systems for targeting, accessing and diagnosing diseased lung compartments are disclosed. The method comprises introducing a diagnostic catheter with an occluding member at its distal end into a lung segment via an assisted ventilation device; inflating the occluding member to isolate the lung segment; and performing a diagnostic procedure with the catheter while the patient is ventilated. The proximal end of the diagnostic catheter is configured to be attached to a console. The method may also comprise introducing the diagnostic catheter into the lung segment; inflating the occluding member to isolate the lung segment; and monitoring blood oxygen saturation. The method may further comprise introducing the diagnostic catheter into the lung segment; determining tidal flow volume in the lung segment; determining total lung capacity of the patient; and determining a flow rank value based on the tidal flow volume of the lung segment and the total lung capacity.

74. 发明申请

US20200038086A1 SELECTIVE LUNG TISSUE ABLATION 审中-公开
公开(公告)号：US20200038086A1
公开(公告)日：2020-02-06
申请号：US16590804
申请日：2019-10-02
申请人： Pulmonx Corporation
发明人： Peter P. Soltesz , Nikolai Aljuri , Ajit Nair
IPC分类号： A61B18/00 , A61B18/20 , A61N7/02 , A61N5/10 , A61M16/04 , A61M16/00 , A61B18/18 , A61B18/14 , A61B18/12 , A61B18/02 , A61B18/08
摘要： Medical methods and systems are provided for effecting lung volume reduction by selectively ablating segments of lung tissue.

75. 发明授权

US10314516B2 Methods and systems for endobronchial diagnosis 有权
公开(公告)号：US10314516B2
公开(公告)日：2019-06-11
申请号：US15159670
申请日：2016-05-19
申请人： PulmonX Corporation
发明人： Surag Mantri
IPC分类号： A61B5/00 , A61B5/087 , A61B5/091
摘要： A method of diagnosing an air leak in a lung compartment of a patient may include: advancing a diagnostic catheter into an airway leading to the lung compartment; inflating an occluding member on the catheter to form a seal with a wall of the airway and thus isolate the lung compartment; measuring air pressure within the lung compartment during multiple breaths, using the diagnostic catheter; displaying the measured air pressure as an air pressure value on a console coupled with the diagnostic catheter; and determining whether an air leak is present in the lung compartment based on the displayed air pressure value during the multiple breaths.

76. 发明申请

US20180092731A1 HIGH RESISTANCE IMPLANTED BRONCHIAL ISOLATION DEVICES AND METHODS 审中-公开
公开(公告)号：US20180092731A1
公开(公告)日：2018-04-05
申请号：US15714868
申请日：2017-09-25
申请人： Pulmonx Corporation
发明人： Sri Radhakrishnan , Ryan Olivera
IPC分类号： A61F2/04 , A61B17/12 , A61M16/20
摘要： Disclosed are methods and devices for regulating fluid flow to and from a region of a patient's lung, such as to achieve a desired fluid flow dynamic to a lung region during respiration and/or to induce collapse in one or more lung regions. Pursuant to an exemplary procedure, an identified region of the lung is targeted for treatment. The targeted lung region is then bronchially isolated to regulate airflow into and/or out of the targeted lung region through one or more bronchial passageways that feed air to the targeted lung region. An exemplary flow control device is configured to block fluid flow in the inspiratory direction and the expiratory direction at normal breathing pressures and allow fluid flow in the expiratory direction at coughing pressures.

77. 发明授权

US09592008B2 Devices and systems for lung treatment 有权
标题翻译：用于肺部治疗的装置和系统
公开(公告)号：US09592008B2
公开(公告)日：2017-03-14
申请号：US13174565
申请日：2011-06-30
申请人： Ryan Olivera , Srikanth Radhakrishnan
发明人： Ryan Olivera , Srikanth Radhakrishnan
IPC分类号： A61B5/00 , A61B5/107
CPC分类号： A61F2/04 , A61B1/018 , A61B1/2676 , A61B5/1076 , A61B5/6852 , A61B17/12104 , A61B2017/0034 , A61B2090/061 , A61F2002/043 , A61M2025/0008
摘要： Devices, systems, and methods for measuring the diameter of an airway in a human or animal subject are disclosed. The device comprises a flexible catheter body having a proximal end and a distal end. Flexible sizing elements are disposed along and extend approximately orthogonally from the catheter body. The sizing elements have different heights from one another and are configured to fit through the working channel of a bronchoscope. Devices, systems, and methods for redirecting airflow through a lung airway are also disclosed. The method comprises introducing into the airway a catheter comprising a distal end, a proximal end and an elongated portion therebetween, wherein the distal end comprises an airway closing mechanism, and wherein the proximal end comprises an actuator to actuate the airway closing mechanism; and actuating the airway closing mechanism to at least partially close the airway.
摘要翻译：公开了用于测量人或动物受试者中气道直径的装置，系统和方法。该装置包括具有近端和远端的柔性导管本体。灵活的施胶元件沿导管本体大致正交地设置并延伸。尺寸调节元件彼此具有不同的高度，并且被配置成穿过支气管镜的工作通道。还公开了用于将气流重定向通过肺气道的装置，系统和方法。该方法包括将包括远端，近端和其间的细长部分的导管引入气道中，其中远端包括气道关闭机构，并且其中近端包括用于致动气道闭合机构的致动器; 并且致动气道关闭机构以至少部分地关闭气道。

78. 发明授权

US09533116B2 Methods and devices for passive residual lung volume reduction and functional lung volume expansion 有权
标题翻译：被动残余肺容积减少和功能性肺容积扩张的方法和装置
公开(公告)号：US09533116B2
公开(公告)日：2017-01-03
申请号：US13938025
申请日：2013-07-09
申请人： Pulmonx Corporation
发明人： Nikolai Alijuri , Rodney C. Perkins , Niyazi Beyhan
IPC分类号： A61M16/04 , A61M16/20 , A61M39/22 , A61B5/08 , A61B17/12 , A61B6/03 , A61M16/00 , A61M25/10
CPC分类号： A61B17/12104 , A61B5/055 , A61B5/08 , A61B5/0813 , A61B5/085 , A61B5/6853 , A61B6/03 , A61B6/032 , A61B17/1204 , A61B17/12136 , A61B2017/00022 , A61M16/0434 , A61M16/208 , A61M25/10 , A61M2016/0027 , A61M2016/003 , A61M2025/1052 , A61M2205/3303 , A61M2205/3334 , A61M2205/3344 , A61M2210/1035 , A61M2230/46
摘要： The volume of a hyperinflated lung compartment is reduced by sealing a distal end of the catheter in an airway feeding the lung compartment. Air passes out of the lung compartment through a passage in the catheter while the patient exhales. A one-way flow element associated with the catheter prevents air from re-entering the lung compartment as the patient inhales. Over time, the pressure of regions surrounding the lung compartment cause it to collapse as the volume of air diminishes. Residual volume reduction effectively results in functional lung volume expansion. Optionally, the lung compartment may be sealed in order to permanently prevent air from re-entering the lung compartment.
摘要翻译：通过在进入肺隔室的气道中密封导管的远端来减少超膨胀的肺隔室的体积。当患者呼气时，空气通过导管中的通道从肺隔间通过。与导管相关联的单向流动元件防止空气在患者吸入时再次进入肺隔室。随着时间的推移，随着空气体积的减小，肺室周围的区域压力会使其崩溃。残余体积减少有效地导致功能性肺容积扩张。任选地，肺隔室可以被密封以便永久地防止空气重新进入肺隔室。

79. 发明授权

US09439583B2 Functional assessment and treatment catheters and methods for their use in the lung 有权
公开(公告)号：US09439583B2
公开(公告)日：2016-09-13
申请号：US13689344
申请日：2012-11-29
申请人： Pulmonx Corporation
发明人： Ajit Nair , Son Gia , Roger Farhnoltz , Nikolai Aljuri
IPC分类号： A61M16/04 , A61M25/01 , A61B5/08 , A61B5/097 , A61B5/085 , A61M25/00 , A61M25/06 , A61B5/00 , A61B17/12 , A61F2/04
CPC分类号： A61B5/4836 , A61B5/08 , A61B5/085 , A61B5/097 , A61B5/6853 , A61B17/12104 , A61F2002/043 , A61M16/04 , A61M16/0406 , A61M16/0866 , A61M25/0075 , A61M25/0662 , A61M2025/0004 , A61M2025/0681
摘要： Lung conditions are diagnosed and optionally treated using a functional assessment catheter or a functional lung assessment and treatment catheter. A flow restrictive component is initially placed in a bronchus or lung passageway upstream from a diseased lung region. The isolated lung region is then functionally assessed through the catheter, while the flow restrictive component remains in place. If the patient is a good candidate for treatment by occlusive or restrictive treatment techniques, the flow resistive component may be left in place. If the patient is not suitable for such treatment, the flow resistive component may be removed.

80. 发明申请

US20140018605A1 SELECTIVE LUNG TISSUE ABLATION 有权
标题翻译：选择性肺组织消退
公开(公告)号：US20140018605A1
公开(公告)日：2014-01-16
申请号：US14033163
申请日：2013-09-20
申请人： Pulmonx Corporation
发明人： Peter P. Soltesz , Nikolai Aljuri , Ajit Nair
IPC分类号： A61B18/02 , A61B18/08 , A61B18/18 , A61M16/04 , A61N5/10 , A61N7/02 , A61M16/00 , A61B18/14 , A61B18/12
CPC分类号： A61B18/00 , A61B18/0206 , A61B18/082 , A61B18/1206 , A61B18/14 , A61B18/1492 , A61B18/1815 , A61B18/20 , A61B2018/00214 , A61B2018/0022 , A61B2018/00541 , A61B2018/00642 , A61B2018/00714 , A61B2018/00797 , A61B2018/00994 , A61B2018/0212 , A61B2018/044 , A61B2018/1435 , A61B2018/144 , A61B2018/1472 , A61B2018/1807 , A61B2018/1861 , A61M16/0057 , A61M16/0434 , A61M16/0463 , A61N5/1001 , A61N7/022
摘要： Medical methods and systems are provided for effecting lung volume reduction by selectively ablating segments of lung tissue.
摘要翻译：提供了通过选择性消融肺组织片段来实现肺容量减小的医学方法和系统。

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