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71. 发明申请

US20090301151A1 LUBRICANT COMPOSITION FOR HOT METAL WORKING AND METHOD OF HOT METAL WORKING USING THE SAME 有权
标题翻译：用于热金属加工的润滑剂组合物及使用该金属加工的热金属加工方法
公开(公告)号：US20090301151A1
公开(公告)日：2009-12-10
申请号：US12296518
申请日：2007-03-29
申请人： Kazuhiro Shimoda , Tomio Yamakawa , Kazutaka Asabe , Hirokazu Okada , Yasuyoshi Hidaka , Sumio Iida , Naoya Hirase , Kenji Takeuchi , Suichi Akiyama
发明人： Kazuhiro Shimoda , Tomio Yamakawa , Kazutaka Asabe , Hirokazu Okada , Yasuyoshi Hidaka , Sumio Iida , Naoya Hirase , Kenji Takeuchi , Suichi Akiyama
IPC分类号： B21B45/02 , C03C8/22
CPC分类号： C10M173/02 , B21B19/04 , B21B25/04 , C10M2201/041 , C10M2201/05 , C10M2201/062 , C10M2201/103 , C10M2201/12 , C10N2220/022 , C10N2230/06 , C10N2240/403 , C10N2240/404 , C10N2240/409 , C10N2250/121 , Y10T29/49885 , C10N2210/03 , C10N2210/01 , C10N2210/02
摘要： The present invention provides a lubricant composition for hot metal working which is capable of inhibiting generation of flaws on the surface of materials to be provided for hot metal working, and provides a method of hot metal working. The invention provides a lubricant composition for hot metal working comprising a plurality of glass frits respectively having different softening point from each other.
摘要翻译：本发明提供了一种用于热金属加工的润滑剂组合物，其能够抑制用于热金属加工的材料的表面上的缺陷的产生，并且提供了一种热金属加工方法。本发明提供了一种用于热金属加工的润滑剂组合物，其包括分别具有彼此不同软化点的多个玻璃料。

72. 发明授权

US07598254B2 Substituted 1,3-thiazolo[5,4-d]pyrimidines as xanthine oxidase inhibitors 有权
标题翻译：取代的1,3-噻唑并[5,4-d]嘧啶黄嘌呤氧化酶抑制剂
公开(公告)号：US07598254B2
公开(公告)日：2009-10-06
申请号：US11629277
申请日：2005-06-13
申请人： Shinichi Yoshida , Kunio Kobayashi , Nobutaka Mochiduki , Tomio Yamakawa , Tadashi Kobayashi , Yoriko Shinohara
发明人： Shinichi Yoshida , Kunio Kobayashi , Nobutaka Mochiduki , Tomio Yamakawa , Tadashi Kobayashi , Yoriko Shinohara
IPC分类号： C07D513/04 , A61K31/519 , A61P19/06 , C07D515/04
CPC分类号： C07D513/04 , C07D498/04
摘要： The invention relates to compounds of the following formula (I) or their salts: in which R1 is a group of phenyl, naphthyl, pyridyl or the like which may have a substituent such as an alkyl group having 1-8 carbon atoms, an alkoxy group having 1-8 carbon atoms, an alkoxycarbonyl group having 2-8 carbon atoms, carboxyl, halogen, hydroxyl, nitro, or cyano; R2 is cyano, nitro, or the like; R3 is hydroxyl or the like; X is oxygen, sulfur, or the like; and Y is oxygen or sulfur, and a xanthine oxidase inhibitor containing the compound.
摘要翻译：本发明涉及下式（I）的化合物或其盐：其中R 1为可具有取代基的苯基，萘基，吡啶基等基团，例如具有1-8个碳原子的烷基，烷氧基具有1-8个碳原子的基团，具有2-8个碳原子的烷氧基羰基，羧基，卤素，羟基，硝基或氰基; R2是氰基，硝基等; R3是羟基等; X是氧，硫等; Y为氧或硫，含有该化合物的黄嘌呤氧化酶抑制剂。

73. 发明申请

US20090030041A1 N-substituted N-(4-piperidinyl) Amide Derivative 审中-公开
标题翻译： N-取代的N-（4-哌啶基）酰胺衍生物
公开(公告)号：US20090030041A1
公开(公告)日：2009-01-29
申请号：US11662633
申请日：2005-09-13
申请人： Toshihiro Takahashi , Tsuyoshi Endo , Masatoshi Ushioda , Kunio Kobayashi , Tomio Yamakawa , Kiichi Shika , Toru Kawasaki , Toshiyasu Imai , Kenji Hirate , Takako Hirate
发明人： Toshihiro Takahashi , Tsuyoshi Endo , Masatoshi Ushioda , Kunio Kobayashi , Tomio Yamakawa , Kiichi Shika , Toru Kawasaki , Toshiyasu Imai , Kenji Hirate , Takako Hirate
IPC分类号： A61K31/4525 , C07D405/02 , A61P25/04
CPC分类号： C07D211/58 , C07D405/12 , C07D409/12
摘要： An N-substituted N-(4-piperininyl)amide derivative represented by the following formula (I): (wherein R1 represents C1-6 alkyl, furyl, etc.; R2 represents amino, acetylamino, ureido, etc.; R3 represents hydrogen, C2-8 alkoxycarbonyl, etc.; R4 represents optionally substituted phenyl, etc.; R5 represents hydroxyl, benzyloxy, etc.; R6 represents hydrogen or methyl; and m is 1 or 2) or a salt of the derivative, and an analgesic containing the derivative or salt.
摘要翻译：由下式（I）表示的N-取代的N-（4-哌啶基）酰胺衍生物：其中R1表示C1-6烷基，呋喃基等; R2表示氨基，乙酰氨基，脲基等; R3表示氢，C 2-8烷氧基羰基等; R 4表示任选取代的苯基等; R 5表示羟基，苄氧基等; R 6表示氢或甲基; m表示1或2）或该衍生物的盐，以及镇痛剂含有衍生物或盐。

74. 发明授权

US07260966B2 Tube shell for manufacturing a seamless steel pipe and a method for its manufacture 有权
标题翻译：用于制造无缝钢管的管壳及其制造方法
公开(公告)号：US07260966B2
公开(公告)日：2007-08-28
申请号：US11312934
申请日：2005-12-21
申请人： Kazuhiro Shimoda , Tomio Yamakawa , Hiroyuki Semba , Hirofumi Hori , Tsuneo Kondo
发明人： Kazuhiro Shimoda , Tomio Yamakawa , Hiroyuki Semba , Hirofumi Hori , Tsuneo Kondo
IPC分类号： B21B19/04
CPC分类号： C22C38/44 , B21B3/02 , B21B19/04 , C22C38/02 , C22C38/58 , Y10S72/70
摘要： A pierced shell of an austenitic stainless steel having a good inner surface condition is provided, and a means is established which can perform mass production on an industrial scale of a good quality seamless steel pipe of stainless steel. An austenitic stainless steel billet with a P content of at most 0.040% and an S content of at most 0.020% is pierced under conditions such that the pipe expansion ratio H (outer diameter of shell/diameter of billet to be worked) satisfies the following equation to obtain a tube shell of an austenitic stainless steel. {P(%)/(0.025×H−0.01)}2+{S(%)/(0.015×H−0.01)}2≦1. When manufacturing a seamless steel pipe of an austenitic stainless steel, the above-described shell is rolled to form a pipe.
摘要翻译：提供了具有良好的内表面状态的奥氏体不锈钢的穿孔壳，并且建立了可以在不锈钢质量好的无缝钢管的工业规模上进行批量生产的手段。在膨胀比H（壳的外径/待加工坯料直径）满足以下条件的条件下，对P含量为0.040％以下且S含量为0.020％以下的奥氏体不锈钢坯料进行穿孔获得奥氏体不锈钢管壳的方程式。 {P（％）/（0.025×H-0.01）} 2 + {S（％）/（0.015xH-0.01）} 2 <= 1。当制造奥氏体不锈钢的无缝钢管时，将上述壳轧制成管。

75. 发明申请

US20050096363A1 Activator of peroxisome proliferator-activated receptor delta 有权
标题翻译：过氧化物酶体增殖物激活受体δ的活化剂
公开(公告)号：US20050096363A1
公开(公告)日：2005-05-05
申请号：US10491935
申请日：2002-10-09
申请人： Shogo Sakuma , Tomio Yamakawa , Takashi Kanda , Seiichiro Masui
发明人： Shogo Sakuma , Tomio Yamakawa , Takashi Kanda , Seiichiro Masui
IPC分类号： A61K31/00 , A61K31/423 , A61K31/427 , A61K31/454 , A61P3/04 , A61P3/06 , A61P3/10 , A61P9/00 , A61P9/10 , A61P19/10 , A61P25/28 , A61P29/00 , A61P35/00 , C07D403/06 , C07D405/06 , C07D409/06 , C07D413/06 , C07D413/12 , C07D413/14 , C07D417/06 , C07D417/12 , C07D417/14 , A61K31/4178 , A61K31/422 , A61K31/4439 , C07D43/14
CPC分类号： C07D403/06 , A61K31/00 , A61K31/423 , A61K31/427 , A61K31/454 , C07D405/06 , C07D409/06 , C07D413/06 , C07D413/12 , C07D413/14 , C07D417/06 , C07D417/12 , C07D417/14
摘要： A compound represented by the formula (I) or a salt of the compound, and a PPAR-δ activator which contains the compound or salt as the active ingredient: (wherein A represents O or S; B1 represents N, etc.; B2 represents O, etc.; each of X1 and X2 represents O, S, a bond, etc.; Y represents C1-8 alkylene chain; Z represents O or S; R1 represents aryl, etc. which can have substituents; R2 represents C1-8 alkyl, etc.; R3 represents C1-8 alkyl, C2-8 alkenyl, etc.; each of R4 and R5 represents hydrogen, C1-8 alkyl, etc.; and R6 represents hydrogen, etc.; provided that each of Z and R3 is attached to the benzene ring, and X2 is not attached to the benzene ring).
摘要翻译：由式（I）表示的化合物或化合物的盐和含有该化合物或盐作为活性成分的PPAR-δ活化剂：（其中A表示O或S; B < 表示N等; B 2表示O等; X 1和X 2各自表示O，S，键， Y表示C 1-8亚烷基链; Z表示O或S; R 1表示可具有取代基的芳基等; R 2， / SUP表示C 1-8烷基等; R 3表示C 1-8烷基，C 2-8 链烯基等; R 4和R 5各自代表氢，C 1-8烷基等;和 R 6表示氢等;条件是Z和R 3各自连接到苯环上，并且X 2不连接到苯环）。

76. 发明申请

US20050054674A1 Activator of peroxisome proliferator-activated receptor 有权
标题翻译：过氧化物酶体增殖物激活受体的活化剂
公开(公告)号：US20050054674A1
公开(公告)日：2005-03-10
申请号：US10486783
申请日：2002-08-02
申请人： Shogo Sakuma , Tomio Yamakawa , Takashi Kanda , Seiichiro Masui
发明人： Shogo Sakuma , Tomio Yamakawa , Takashi Kanda , Seiichiro Masui
IPC分类号： A61P3/04 , A61P3/06 , A61P3/10 , A61P5/14 , A61P9/00 , A61P9/10 , A61P19/10 , A61P21/04 , A61P25/28 , A61P31/00 , A61P35/00 , A61P43/00 , C07D233/54 , C07D263/32 , C07D263/62 , C07D277/24 , C07D277/26 , A61K31/4709 , A61K31/4178 , A61K31/422 , A61K31/427 , A61K31/4439
CPC分类号： C07D263/62 , C07D263/32 , C07D277/24
摘要： A compound represented by the following general formula (I): (wherein R1 represents phenyl, etc. which can have substituents selected from the group consisting of C1-8 alkyl, C1-8 alkyl having halogen, halogen, hydroxyl, etc.; R2 represents C1-8 alkyl, etc.; A represents oxygen, sulfur, etc.; X represents C1-8 alkylene chain, etc.; Y represents C(═O), CH═CH, etc.; R3, R4, and R5 each represents hydrogen, C1-8 alkyl, etc.; B represents CH or nitrogen; Z represents oxygen or sulfur; R6 and R7 each represents hydrogen, C1-8 alkyl, etc.; and R8 represents hydrogen or C1-8 alkyl; provided that at least one of R3, R4, and R5 is not hydrogen) or a salt of the compound; and a PPAR-δ activator which contains the compound or salt as the active ingredient.
摘要翻译：由以下通式（I）表示的化合物：其中R 1表示可具有选自C 1-8烷基，具有卤素，卤素，羟基等的C 1-8烷基的取代基的苯基等 ; R 2表示C 1-8烷基等; A表示氧，硫等; X表示C 1-8亚烷基链等; Y表示C（= O），CH = CH等; R 3，R 4和R 5各自表示氢，C 1-8烷基等; B表示CH或氮; Z表示氧或硫; R 6和R 7各自表示氢，C 1-8烷基等; R 8表示氢或C 1-8烷基;条件是R 3，R 4和R 5中的至少一个不是氢）或化合物的盐; 和含有该化合物或盐作为活性成分的PPAR-δ活化剂。

77. 发明授权

US5070089A Therapeutic agent for liver disease and piperazine derivatives 失效
标题翻译：用于肝病和哌嗪衍生物的治疗剂
公开(公告)号：US5070089A
公开(公告)日：1991-12-03
申请号：US302552
申请日：1989-01-26
申请人： Mitsuo Masaki , Tomio Yamakawa , Masaru Satoh , Hiromitsu Takeda , Yasushi Yoshino , Hitoshi Matsukura
发明人： Mitsuo Masaki , Tomio Yamakawa , Masaru Satoh , Hiromitsu Takeda , Yasushi Yoshino , Hitoshi Matsukura
IPC分类号： C07D295/21 , C07D317/60 , C07H15/26
CPC分类号： C07D295/21 , C07D317/60 , C07H15/26
摘要： A therapeutic agent for liver disease containing as an active ingredient a piperazine derivative having the formula: ##STR1## wherein, A represents a phenyl, p-benzoquinonyl or cumarinyl group which may have at least one substituent selected from the group consisting of halogen, alkyl, fluoroalkyl, formyl, alkoxycarbonyl, acyl, hydroxy, alkoxy, acyloxy, glycosyloxy, amino, alkylamino, mercapto, alkylthio and nitro; B represents a single bond or a straight chain alkylene group containing 1-4 carbon atoms which may have at least one substituent selected from the group consisting of alkyl, aryl, aralkyl, hydroxy and oxo; R represents an atom or a group selected from the group consisting of hydrogen, alkali metal, alkaline earth metal, alkyl, cycloalkyl, aralkyl and aryl; and n is 2 or 3, or its pharmaceutically acceptable salt is disclosed.

78. 发明授权

US4089196A Method of controlling inter-stand tension in rolling mills 失效
标题翻译：控制轧机间间张力的方法
公开(公告)号：US4089196A
公开(公告)日：1978-05-16
申请号：US781327
申请日：1977-03-25
申请人： Katsuya Kondo , Tomio Yamakawa
发明人： Katsuya Kondo , Tomio Yamakawa
IPC分类号： B21B1/18 , B21B37/00 , B21B37/48 , B21B37/52 , G05D13/62 , B21B37/06
CPC分类号： B21B37/52 , B21B37/48 , B21B1/18
摘要： There is disclosed a method of controlling inter-stand tension in rolling mills in which a tension measuring device is provided on each stand. The tension measuring device comprises a pair of load sensing devices provided respectively at the entry and delivery sides of the roll stand. Difference between outputs from the pair of load sensing devices is used as an output value of the tension measuring device. First, while a workpiece is captured by the second stand but is not yet captured by the third stand and when the tension in the workpiece between the first and second stands is consistent with a desired value, the output value from the tension measuring device of the second stand is stored. After the workpiece has been captured by the third stand, the difference between the stored output value and the output value from the tension measuring device of the second stand is used as the measured value of tension. The tension control for the workpiece between the second and third stands is carried out on the basis of the difference between the measured value and a desired value of tension between the second and third stands.
摘要翻译：公开了一种控制轧机的机架间张力的方法，其中在每个支架上设置张力测量装置。张力测量装置包括分别设置在辊架的入口侧和出口侧的一对负载感测装置。使用来自一对负载感测装置的输出之间的差异作为张力测量装置的输出值。首先，当工件被第二支架捕获但是尚未被第三支架捕获时，并且当第一和第二支架之间的工件中的张力与期望值一致时，来自张力测量装置的输出值第二支架被存储。在第三支架被捕获工件之后，使用来自第二支架的张力测量装置的存储的输出值和输出值之间的差作为张力的测量值。基于第二和第三机架之间的测量值和期望的张力值之间的差异来进行第二和第三机架之间的工件的张力控制。

79. 发明授权

US08784581B2 Fe-Ni alloy pipe stock and method for manufacturing the same 有权
标题翻译：铁镍合金管材及其制造方法
公开(公告)号：US08784581B2
公开(公告)日：2014-07-22
申请号：US11643823
申请日：2006-12-22
申请人： Masaaki Igarashi , Kazuhiro Shimoda , Tomio Yamakawa , Hisashi Amaya
发明人： Masaaki Igarashi , Kazuhiro Shimoda , Tomio Yamakawa , Hisashi Amaya
IPC分类号： C21D8/10 , C22C38/00 , C22C38/04
CPC分类号： C22F1/10 , B21B23/00 , C21D8/10 , C22C19/055 , C22C38/02 , C22C38/04 , C22C38/42 , C22C38/44
摘要： An Fe—Ni alloy pipe stock containing, by mass %, C≦0.04%, Si≦0.50%, Mn: 0.01 to 6.0%, P≦0.03%, S≦0.01%, Cr: 20 to 30%, Ni: 30 to 45%, Mo: 0 to 10%, W: 0 to 20%, with Mo(%)+0.5W(%): more than 1.5% to not more than 10%, Cu: 0.01 to 1.5%, Al≦0.01% and N: 0.0005 to 0.20%, and the balance being Fe, with 1440−6000P−100S−2000C≧1300, Ni+10(Mo+0.5W)+100N≦120, (Ni−35)+10(N−0.1)−2(Cr−25)−5(Mo+0.5W−3)+8≧0, can be manufactured into a seamless pipe by use of a Mannesmann piercing and rolling mill because of its excellent inner surface properties. The resulting seamless pipe has excellent mechanical properties and moreover has excellent corrosion resistance in a sour gas environment.
摘要翻译：一种Fe-Ni合金管材，以质量％计含有C％，0.04％，Si＆NlE; 0.50％，Mn：0.01〜6.0％，P＆lt; L; 0.03％，S＆NlE; 0.01％，Cr：20〜30％，Ni：30 〜45％，Mo：0〜10％，W：0〜20％，Mo（％）+ 0.5W（％）：大于1.5％以上10％以下，Cu：0.01〜1.5％ 0.01％，N：0.0005〜0.20％，余量为Fe，1440-6000P-100S-2000C≥300，Ni + 10（Mo + 0.5W）+ 100N＆NlE; 120，（Ni-35）+10 -0.1）-2（Cr-25）-5（Mo + 0.5W-3）+8≥0可由Mannesmann穿孔轧机制成无缝管，因为其内表面性能优异。所得到的无缝管具有优异的机械性能，并且在酸性气体环境中具有优异的耐腐蚀性。

80. 发明申请

US20130255342A1 METHOD FOR PRODUCING SEAMLESS TUBE/PIPE 有权
标题翻译：生产无缝管/管的方法
公开(公告)号：US20130255342A1
公开(公告)日：2013-10-03
申请号：US13991635
申请日：2011-12-06
申请人： Kenichi Saitou , Kazuhiro Shimoda , Tomio Yamakawa
发明人： Kenichi Saitou , Kazuhiro Shimoda , Tomio Yamakawa
IPC分类号： B21B21/02
CPC分类号： B21B21/02 , B21B19/04 , B21B25/00 , B21B2261/08 , B21B2261/10
摘要： By using a piercing mill that includes a pusher on the entrance side, a plug on the exit side along a pass line, and a plurality of angled rolls as being provided around the plug so as face to each other, in the case where the maximum diameter of an unsound region consisting of center segregation and porosity in a cross section of a billet is d [mm], piercing-rolling is performed under the condition that the plug nose rolling reduction ratio (TDF) expressed by Formula (1) satisfies Formula (2). TDF=(Bd−D1)/Bd (1) TDF≦−0.50×(d/Bd)+0.06 (6) In Formulae (1) and (2), Bd is the billet diameter [mm], and D1 is the opening [mm] between the angled rolls at the plug nose position. Thereby, when piercing-rolling is performed, the occurrence of an inner surface flaw attributable to the center segregation and porosity in the billet can be prevented reliably.
摘要翻译：通过使用包括在入口侧的推动器的穿孔机，沿着通行线的出口侧的塞子和在插头周围设置成彼此面对的多个成角度的辊，在最大值在坯料的横截面中由中心偏析和孔隙率组成的不固定区域的直径为d [mm]，在由式（1）表示的塞子前端滚动压下率（TDF）满足公式的条件下进行穿孔轧制（2）。 TDF =（Bd-D1）/ Bd（1）TDF@-0.50×（d / Bd）+0.06（6）在公式（1）和（2）中，Bd是坯料直径[mm]，D1是在插头前端位置的成角度的卷轴之间打开[mm]。因此，当进行穿孔轧制时，可以可靠地防止由于中心偏析引起的内表面缺陷的发生和坯料中的孔隙率的发生。

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