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    • 72. 发明申请
    • Process for the synthesis of azetidinones
    • 合成氮杂环丁酮的方法
    • US20060135755A1
    • 2006-06-22
    • US11305926
    • 2005-12-19
    • Tiruvettipuram ThiruvengadamJohn ChiuXiaoyong FuTimothy McAllister
    • Tiruvettipuram ThiruvengadamJohn ChiuXiaoyong FuTimothy McAllister
    • C07D205/02C07H17/02
    • C07D205/08C07H17/02
    • A process is provided for preparing azetidinones useful as intermediates in the synthesis of penems and as hypocholesterolemic agents, comprising reacting a β-(substituted-amino)amide, a β-(substituted-amino)acid ester, or a β-(substituted-amino)thiolcarbonic acid ester with a silylating agent and a cyclizing agent selected from the group consisting of alkali metal carboxylates, quaternary ammonium carboxylates, quaternary ammonium hydroxides, quaternary ammonium alkoxides, quaternary ammonium aryloxides and hydrates thereof, or the reaction product of: (i) at least one quaternary ammonium halide and at least one alkali metal carboxylate; or (ii) at least one quaternary ammonium chloride, quaternary ammonium bromide, or quaternary ammonium iodide and at least one alkali metal fluoride, wherein a quaternary ammonium moiety of the cyclizing agent is unsubstituted or substituted by one to four groups independently selected from the group consisting of alkyl, arylalkyl and arylalkyl-alkyl.
    • 提供了一种制备氮杂环丁酮的方法,该氮杂环丁酮可用作Penems的合成中的中间体和低胆固醇血症药,包括使β-(取代的 - 氨基)酰胺,β-(取代的 - 氨基)酸酯或β-(取代的 - 氨基) 氨基)硫代碳酸酯与甲硅烷基化剂和选自碱金属羧酸盐,季铵羧酸盐,季铵氢氧化物,季铵醇盐,季铵氧化物及其水合物的环化剂,或其反应产物:(i )至少一种季铵卤化物和至少一种碱金属羧酸盐; 或(ii)至少一种季铵氯化物,季铵溴化物或季铵碘化物和至少一种碱金属氟化物,其中环化剂的季铵部分是未取代的或被一至四个独立地选自 由烷基,芳烷基和芳基烷基 - 烷基组成。
    • 74. 发明授权
    • Refrigeration appliance with impingement cooling system
    • 具有冲击冷却系统的制冷设备
    • US06422031B1
    • 2002-07-23
    • US09929079
    • 2001-08-15
    • Sheldon W. MandelBehrooz MohebbiXiaoyong Fu
    • Sheldon W. MandelBehrooz MohebbiXiaoyong Fu
    • F25D1704
    • F25D19/04F25D11/006F25D17/062F25D23/10F25D25/02F25D2317/0664F25D2317/0665F25D2400/08F25D2400/28F25D2400/30
    • A refrigeration appliance includes a large capacity refrigeration system for developing a flow of cold air that is impinged, preferably through top and side nozzles, upon food items placed within an internal cavity of the appliance to quickly freeze or chill the food items. An additional small capacity refrigeration system is provided to maintain a desired temperature within the cavity when the rapid cooling is not needed. Preferably, an impingement air diffuser arrangement is provided to direct the air flow and includes partition members to divide the internal cavity into subspaces for different food packages, with varying cooling rates being permissible between the various sub-spaces. A vertically adjustable shelf is provided which cooperates with blocking plates which move up and down with the shelf and function to block air flow through nozzles arranged below the shelf such that all of the developed air flow is used for direct impingement on the food product.
    • 制冷装置包括大容量制冷系统,用于将优选通过顶部和侧面喷嘴撞击的冷空气流放置在放置在器具的内部空腔内的食品上,以快速冷冻或冷却食品。 当不需要快速冷却时,提供另外的小容量制冷系统以在空腔内保持期望的温度。 优选地,提供冲击空气扩散器布置以引导空气流并且包括分隔构件以将内部空腔划分成用于不同食品包装的子空间,其中在各个子空间之间允许变化的冷却速率。 提供了一个可垂直调节的搁板,与搁板一起上下移动的阻挡板,其功能是阻止通过布置在货架下方的喷嘴的气流,使得所有显影的气流用于直接冲击食品。