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71. 发明授权

US07748895B2 Method and system for real-time estimation and prediction of the thermal state of a microprocessor unit 失效
标题翻译：用于实时估计和预测微处理器单元的热状态的方法和系统
公开(公告)号：US07748895B2
公开(公告)日：2010-07-06
申请号：US11930633
申请日：2007-10-31
申请人： Sri M. Sri-Jayantha , Hien P. Dang , Arun Sharma
发明人： Sri M. Sri-Jayantha , Hien P. Dang , Arun Sharma
IPC分类号： G01K1/00 , G01K3/00 , G01K13/00
CPC分类号： G06F1/206
摘要： A method (and system) of predicting a thermal state of a transient thermal system, includes combining sensor outputs and thermal parameters to construct a consistent set of estimates of internal temperature of a transient thermal system.
摘要翻译：预测瞬态热系统的热状态的方法（和系统）包括组合传感器输出和热参数以构成瞬态热系统内部温度的一致性估计集合。

72. 发明授权

US07732894B2 Electronic components on trenched substrates and method of forming same 失效
公开(公告)号：US07732894B2
公开(公告)日：2010-06-08
申请号：US12030274
申请日：2008-02-13
申请人： David Questad , Vijayeshwar D. Khanna , Jennifer V. Muney , Arun Sharma , Sri M. Sri-Jayantha , Lorenzo Valdevit
发明人： David Questad , Vijayeshwar D. Khanna , Jennifer V. Muney , Arun Sharma , Sri M. Sri-Jayantha , Lorenzo Valdevit
IPC分类号： H01L23/48
CPC分类号： H01L28/40 , H01L2224/16225 , H01L2224/32225 , H01L2224/73204 , H01L2924/00011 , H01L2924/00014 , H01L2924/15174 , H01L2924/15311 , H05K1/0231 , H05K1/0271 , H05K1/111 , H05K3/3436 , H05K3/3442 , H05K2201/09036 , H05K2201/10015 , H05K2201/10727 , Y02P70/613 , Y10T29/4913 , Y10T428/24479 , H01L2224/0401 , H01L2924/00
摘要： A method of mounting an electronic component on a substrate includes forming at least one trench in a surface of the substrate. The trenches formed in the substrate reduce a stiffness of the substrate, which provides less resistance to shear. Accordingly, the trenches reduce the amount of strain on the joints, which mount the electronic component to the substrate, which enhances the life of the joints.

73. 发明授权

US07695188B2 Method and system for real-time estimation and prediction of the thermal state of a microprocessor unit 失效
标题翻译：用于实时估计和预测微处理器单元的热状态的方法和系统
公开(公告)号：US07695188B2
公开(公告)日：2010-04-13
申请号：US12021242
申请日：2008-01-28
申请人： Sri M. Sri-Jayantha , Hien P. Dang , Arun Sharma
发明人： Sri M. Sri-Jayantha , Hien P. Dang , Arun Sharma
IPC分类号： G01K7/00 , G01K3/00 , G01J5/00
CPC分类号： G06F1/206
摘要： An apparatus for predicting a thermal state of a system including a semiconductor chip includes a plurality of sensors formed on the semiconductor chip for measuring a temperature at first locations of the semiconductor chip, a model developer for developing a model for estimating a temperature at second locations of the semiconductor chip which are other than the first locations, a mapping unit for mapping an instruction cache associated with the chip into a sequence of X-Y distributed quanta of heat packets, and a predicting unit for predicting a future temperature of the chip based on an execution of an instruction stream in the instruction cache.
摘要翻译：一种用于预测包括半导体芯片的系统的热状态的装置包括形成在半导体芯片上的用于测量半导体芯片的第一位置处的温度的多个传感器，用于开发用于估计第二位置处的温度的模型的模型显影器所述半导体芯片不同于所述第一位置，映射单元，用于将与所述芯片相关联的指令高速缓存到热分组的XY分布量子序列中;以及预测单元，用于基于所述芯片的未来温度预测执行指令缓存中的指令流。

74. 发明授权

US07673158B2 Instruction set with thermal opcode for high-performance microprocessor, microprocessor, and method therefor 失效
公开(公告)号：US07673158B2
公开(公告)日：2010-03-02
申请号：US11933910
申请日：2007-11-01
申请人： Hien P. Dang , Arun Sharma , Sri M. Sri-Jayantha
发明人： Hien P. Dang , Arun Sharma , Sri M. Sri-Jayantha
IPC分类号： G06F1/00
CPC分类号： G06F9/30181 , G06F1/206 , G06F9/30083 , G06F9/30145 , G06F9/30167 , G06F9/383 , G06F9/3885 , Y02D10/16
摘要： A method (and system) of managing heat in an electrical circuit, includes using a thermal instruction appended to an instruction to be processed to determine a heat load associated with the instruction.

75. 发明申请

US20090310848A1 Characterizing Thermomechanical Properties of an Organic Substrate Using Finite Element Analysis 有权
标题翻译：使用有限元分析表征有机基板的热机械性能
公开(公告)号：US20090310848A1
公开(公告)日：2009-12-17
申请号：US12260693
申请日：2008-10-29
申请人： Hien Phu Dang , Arun Sharma , Sri M. Sri-Jayantha
发明人： Hien Phu Dang , Arun Sharma , Sri M. Sri-Jayantha
IPC分类号： G06K9/00
CPC分类号： G06F17/5018 , G06F2217/80
摘要： A method for characterizing thermomechanical properties of an organic substrate is provided. The method includes the steps of: receiving an image of the organic substrate, the image including a geometric description of the plurality of circuit layers of the substrate; selecting a given one of the plurality of circuit layers for processing; converting the image to a two-dimensional finite element model (FEM) image of the given one of the circuit layers; determining at least one of a coefficient of thermal expansion (CTE), modulus and Poisson's ratio of the FEM image of the given one of the circuit layers; repeating the steps of selecting a given one of the plurality of circuit layers, converting the image to a two-dimensional FEM image, and determining at least one of a CTE, modulus and Poisson's ratio of the FEM image for all of the plurality of circuit layers corresponding to at least a portion of the organic substrate; and constructing a three-dimensional representation of at least a portion of the organic substrate including the plurality of circuit layers as a function of at least one of the CTE, modulus and Poisson's ratio of each of the plurality of circuit layers.
摘要翻译：提供了表征有机基板的热机械性能的方法。该方法包括以下步骤：接收有机衬底的图像，该图像包括衬底的多个电路层的几何描述; 选择所述多个电路层中的给定一个以进行处理; 将图像转换成给定的一个电路层的二维有限元模型（FEM）图像; 确定给定一个电路层的FEM图像的热膨胀系数（CTE），模数和泊松比中的至少一个; 重复选择多个电路层中的给定的一个电路层的步骤，将图像转换为二维有机图像，以及确定所有多个电路中的有限元图像的CTE，模数和泊松比中的至少一个对应于有机基材的至少一部分的层; 以及构成包括所述多个电路层的所述有机衬底的至少一部分的三维表示作为所述多个电路层中的每一个的CTE，模数和泊松比中的至少一个的函数。

76. 发明授权

US07612167B2 Human hematopoietic growth regulatory gene product 失效
标题翻译：人造血生长调节基因产物
公开(公告)号：US07612167B2
公开(公告)日：2009-11-03
申请号：US11141072
申请日：2005-05-31
申请人： Arun Sharma , Ronald Hoffman
发明人： Arun Sharma , Ronald Hoffman
IPC分类号： C07K14/435 , C07K14/47 , C07K14/475 , C12N5/00 , C12N5/06 , C12N5/08
CPC分类号： C12N5/0647 , C07K14/4702 , C12N2501/125 , C12N2501/23 , C12N2501/40 , C12N2510/00
摘要： The present invention relates to novel human hiwi protein and genes that encode such proteins. The invention is directed toward the isolation and characterization of human hiwi proteins. The invention specifically provides isolated complementary DNA copies of mRNA corresponding to a human hiwi gene. Also provided are recombinant expression constructs capable of expressing the human hiwi gene of the invention in cultures of transformed prokaryotic and eukaryotic cells, as well as such cultures of transformed cells that synthesize the human hiwi proteins encoded therein. The invention also provides methods for isolating human hematopoietic stem cells.
摘要翻译：本发明涉及编码这种蛋白质的新型人类hiwi蛋白质和基因。本发明涉及人类hiwi蛋白的分离和表征。本发明特别提供了与人hiwi基因相对应的mRNA的分离的互补DNA拷贝。还提供了能够在转化的原核和真核细胞的培养物中表达本发明的人hiwi基因以及合成其中编码的人hiwi蛋白的转化细胞的这种培养物的重组表达构建体。本发明还提供了分离人类造血干细胞的方法。

77. 发明授权

US07583044B2 Servo system for a two-dimensional micro-electromechanical system (MEMS)-based scanner and method therefor 有权
标题翻译：用于二维微机电系统（MEMS）的扫描仪及其方法的伺服系统
公开(公告)号：US07583044B2
公开(公告)日：2009-09-01
申请号：US12141121
申请日：2008-06-18
申请人： Sri M. Sri-Jayantha , Hien Dang , Arun Sharma , Evangelos S. Eleftheriou , Mark A. Lantz , Charalampos Pozidis
发明人： Sri M. Sri-Jayantha , Hien Dang , Arun Sharma , Evangelos S. Eleftheriou , Mark A. Lantz , Charalampos Pozidis
IPC分类号： G05B1/06
CPC分类号： G11B7/0901 , G11B7/08505 , G11B7/0941
摘要： A servo control system micro-electromechanical systems (MEMS)-based motion control system (and method therefor), includes a motion generator having an inherent stiffness component.
摘要翻译：基于微机电系统（MEMS）的运动控制系统（及其方法）包括具有固有刚度分量的运动发生器。

78. 发明申请

US20080284365A1 SERVO SYSTEM FOR A TWO-DIMENSIONAL MICRO-ELECTROMECHANICAL SYSTEM (MEMS)-BASED SCANNER AND METHOD THEREFOR 有权
标题翻译：用于二维微机电系统（MEMS）的伺服系统 - 扫描仪及其方法
公开(公告)号：US20080284365A1
公开(公告)日：2008-11-20
申请号：US12141121
申请日：2008-06-18
申请人： Sri M. Sri-Jayantha , Hien Dang , Arun Sharma , Evangelos S. Eleftheriou , Mark A. Lantz , Charalampos Pozidis
发明人： Sri M. Sri-Jayantha , Hien Dang , Arun Sharma , Evangelos S. Eleftheriou , Mark A. Lantz , Charalampos Pozidis
IPC分类号： G05B1/06
CPC分类号： G11B7/0901 , G11B7/08505 , G11B7/0941
摘要： A servo control system micro-electromechanical systems (MEMS)-based motion control system (and method therefor), includes a motion generator having an inherent stiffness component.
摘要翻译：基于微机电系统（MEMS）的运动控制系统（及其方法）包括具有固有刚度分量的运动发生器。

79. 发明申请

US20080218990A1 ELECTRONIC COMPONENTS ON TRENCHED SUBSTRATES AND METHOD OF FORMING SAME 有权
公开(公告)号：US20080218990A1
公开(公告)日：2008-09-11
申请号：US12099381
申请日：2008-04-08
申请人： David Questad , Vijayeshwar D. Khanna , Jennifer V. Muncy , Arun Sharma , Sri M. Sri-Jayantha , Lorenzo Valdevit
发明人： David Questad , Vijayeshwar D. Khanna , Jennifer V. Muncy , Arun Sharma , Sri M. Sri-Jayantha , Lorenzo Valdevit
IPC分类号： H05K7/00
CPC分类号： H01L28/40 , H01L2224/16225 , H01L2224/32225 , H01L2224/73204 , H01L2924/00011 , H01L2924/00014 , H01L2924/15174 , H01L2924/15311 , H05K1/0231 , H05K1/0271 , H05K1/111 , H05K3/3436 , H05K3/3442 , H05K2201/09036 , H05K2201/10015 , H05K2201/10727 , Y02P70/613 , Y10T29/4913 , Y10T428/24479 , H01L2224/0401 , H01L2924/00
摘要： A method of mounting an electronic component on a substrate includes forming at least one trench in a surface of the substrate. The trenches formed in the substrate reduce a stiffness of the substrate, which provides less resistance to shear. Accordingly, the trenches reduce the amount of strain on the joints, which mount the electronic component to the substrate, which enhances the life of the joints.

80. 发明申请

US20080064887A1 Method of preparation of anticancer taxanes using 3-[(substituted-2-trialkylsilyl)ethoxycarbon1]-5-oxazolidine carboxylic acids 失效
标题翻译：使用3 - [（取代-2-三烷基甲硅烷基）乙氧基羰基] -5-恶唑烷羧酸制备抗癌紫杉烷的方法
公开(公告)号：US20080064887A1
公开(公告)日：2008-03-13
申请号：US11812180
申请日：2007-06-15
申请人： Arun Sharma , Subrata Sarkar , Jyan Mahanty
发明人： Arun Sharma , Subrata Sarkar , Jyan Mahanty
IPC分类号： C07D305/04
CPC分类号： C07D263/04 , C07D305/14 , C07D413/12
摘要： This invention relates to a process for preparation of taxanes comprising subjecting 7,10-diprotected intermediates 7-O-(2-haloacyl)baccatin III 6c or 7,10-O-di-(2-haloacyl)-10-deacetylbaccatin III 6b to a step of coupling with (4S,5R)-3-[(2-alkyl/aryl-2-trialkylsilyl)ethoxy-carbonyl]-4-aryl-2-substituted-1,3-oxazolidine-5-carboxylic acid 1 in the presence of a condensation agent, an activating agent and an aromatic hydrocarbon to obtain 7-O-[2-(haloacyl)]-13-[(4S,5R)-4-aryl-2-substituted-3(2-unsubstituted/substituted-2-trialkylsilyl)-ethoxycarbonyl-1,3-oxazolidinyl-5-carbonyl]baccatin III 7a or 7,10-di-O [2-(haloacyl)]-13-[(4S,5R)-4-aryl-2-substituted-3-(2-unsubstituted/substituted-2-trialkylsilyl)ethoxy-carbonyl-1, 3-oxazolidinyl-5-carbonyl]-10-deacetylbaccatin III 7b; treating the coupled products 7-O-[2-(haloacyl)]-13-[(4S,5R)-4-aryl-2-substituted-3-(2-substituted-2-trialkylsilyl)ethoxy-carbonyl-1, 3-oxazolidinyl-5-carbonyl]baccatin III 7a or 7,10-di-O-[2[(haloacyl)]-13-[(4S,5R)-4-aryl-2-substituted-3-(2-substituted-2-trialkylsilyl)ethoxycarbonyl-1, 3-oxazolidinyl-5-carbonyl-10-deacetylbaccatin III 7b with tetraalkylammonium halide in a haloalkane to obtain free amine of structure 8; treating free amine 8 with acid chloride or acid anhydride in the presence of a base in a heterogeneous phase to obtain the intermediates of structure 9; subjecting the intermediates of compound 9 to the deprotection of 2-haloacyl group under mild alkaline condition at −20 to +40° C. for 6-24 h in the presence of ammonia or aliphatic amines or aromatic amines or their combination to obtain paclitaxel or docetaxel.
摘要翻译：本发明涉及一种制备紫杉烷的方法，包括将7,10-双保护的中间体7-O-（2-卤代酰基）浆果赤霉素III 6c或7,10-O-二（2-卤代酰基）-10-脱乙酰基浆果赤霉素III 6b （4S，5R）-3 - [（2-烷基/芳基-2-三烷基甲硅烷基）乙氧基 - 羰基] -4-芳基-2-取代-1,3-唑烷-5-羧酸1 在缩合剂，活化剂和芳烃存在下，得到7-O- [2-（卤代酰基）] - 13 - [（4S，5R）-4-芳基-2-取代-3（2- 未取代的/取代的2-三烷基甲硅烷基） - 乙氧基羰基-1,3-恶唑烷基-5-羰基]浆果赤霉素III 7a或7,10-二-O- [2-（卤代酰基）] - 13 - [（4S，5R）-4 （2-未取代的/取代的2-三烷基甲硅烷基）乙氧基羰基-1,3-恶唑烷基-5-羰基] -10-脱乙酰基浆果赤霉素III 7b; 处理偶联产物7-O- [2-（卤代酰基）] - 13 - [（4S，5R）-4-芳基-2-取代-3-（2-取代-2-三烷基甲硅烷基）乙氧羰基-1 3-恶唑烷基-5-羰基]浆果赤霉素III 7a或7,10-二-O- [2 [（卤代酰基）] - 13 - [（4S，5R）-4-芳基-2-取代-3- 取代的2-三烷基甲硅烷基）乙氧基羰基-1,3-恶唑烷基-5-羰基-10-脱乙酰基浆果赤霉素III 7b与四烷基卤化铵在卤代烷烃中反应，得到结构8的游离胺; 在碱存在下用酰氯或酸酐处理游离胺8，得到结构9的中间体; 使化合物9的中间体在温和碱性条件下在-20至+ 40℃下在氨或脂族胺或芳族胺或其组合的存在下将2-卤代酰基脱保护6-24小时，得到紫杉醇或多西紫杉醇

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