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71. 发明申请

US20100046815A1 MODEL-BASED CORONARY CENTERLINE LOCALIZATION 有权
标题翻译：基于模型的冠状动脉中心定位
公开(公告)号：US20100046815A1
公开(公告)日：2010-02-25
申请号：US12443490
申请日：2007-09-28
申请人： Jens Von Berg , Bernd Hofmann , Cristian Lorenz , Olivier Ecabert , Jochen Peters , Juergen Weese
发明人： Jens Von Berg , Bernd Hofmann , Cristian Lorenz , Olivier Ecabert , Jochen Peters , Juergen Weese
IPC分类号： G06K9/00
CPC分类号： G06T7/30 , A61B5/055 , A61B6/504 , A61B6/5229 , A61B8/0891 , A61B8/5238 , G06F19/00 , G06T2207/20044 , G06T2207/30101 , Y10S128/922
摘要： The invention relates to a system (100) for registering a vessel model with an image data set based on a joined model comprising a reference object model and the vessel model, the system comprising: a placement unit (110) for placing the joined model in a space of the image data set, thereby creating a placed joined model comprising a placed reference object model and a placed vessel model; a computation unit (120) for computing a deformation field based on a landmark displacement field comprising displacements of landmarks of the placed reference object model relative to corresponding landmarks in the image data set; a transformation unit (130) for transforming the placed joined model using the deformation field, thereby creating a transformed joined model comprising a transformed reference object model and a transformed vessel model; and a registration unit (140) for registering the transformed vessel model with the image data set based on modifying the transformed vessel model and optimizing an objective function of the modified transformed vessel model, wherein the objective function comprises a location-prior term based on a localization of the modified transformed vessel model relative to the transformed joined model. Hence, the system is arranged to model a vessel taking into account the localization of a vessel model relative to a reference anatomical structure described by a reference model.
摘要翻译：本发明涉及一种用于根据包括参考对象模型和血管模型的联合模型将具有图像数据集的血管模型登记的系统（100），该系统包括：一个放置单元（110），用于将连接的模型放置在图像数据集合的空间，从而创建包括放置的参考对象模型和放置的容器模型的放置的连接模型; 计算单元（120），用于基于地标位移场计算变形场，所述地标位移场包括相对于所述图像数据组中的对应地标放置的所述参考对象模型的界标的位移; 变换单元（130），用于使用变形场来变换放置的接合模型，从而创建包括变换的参考对象模型和变换的容器模型的变换的连接模型; 以及注册单元（140），用于基于修改所述经变换的血管模型并优化所述经修改的转化的血管模型的目标函数，将经变换的血管模型与所述图像数据集进行登记，其中所述目标函数包括基于修改的转化血管模型相对于转化的连接模型的定位。因此，该系统被设置成考虑到血管模型相对于由参考模型描述的参考解剖结构的定位来建模血管。

72. 发明授权

US07167172B2 Method of segmenting a three-dimensional structure contained in an object, notably for medical image analysis 有权
标题翻译：分割对象中包含的三维结构的方法，特别是用于医学图像分析
公开(公告)号：US07167172B2
公开(公告)日：2007-01-23
申请号：US10091050
申请日：2002-03-05
申请人： Michael Kaus , Anja Hennemuth , Vladimir Pekar , Juergen Weese
发明人： Michael Kaus , Anja Hennemuth , Vladimir Pekar , Juergen Weese
IPC分类号： G06T15/00
CPC分类号： G06T7/149 , G06T7/12 , G06T2207/10072 , G06T2207/30004
摘要： The invention relates to a method of segmenting a three-dimensional structure, contained in an object, from one or more two-dimensional images which represent a slice of the object. The method utilizes a deformable model whose surface is formed by a network of meshes which connect network points on the surface of the model to one another. First there are determined the meshes which intersect at least one image and a point on the surface of the structure to be segmented is searched along a search line which traverses the mesh and extends in the image. Subsequently, the position of the network points of the model is calculated anew. These steps are repeated a number of times and the model ultimately obtained, that is, after several deformations, is considered to be the segmentation of the three-dimensional structure from the two-dimensional images.
摘要翻译：本发明涉及一种从一个或多个二维图像中分割包含在对象中的三维结构的方法，所述二维图像表示对象的切片。该方法利用可变模型，其表面由网格网络形成，网格网络将模型表面上的网络点彼此连接。首先确定与至少一个图像相交的网格，并且沿着要遍历网格的搜索线搜索要分割的结构的表面上的点，并在图像中延伸。随后，重新计算模型网络点的位置。这些步骤重复多次，并且最终获得的模型，即，在几个变形之后，被认为是来自二维图像的三维结构的分割。

73. 发明申请

US20050288577A1 Apparatus and method for assisting the navigation of a catheter in a vessel 有权
标题翻译：用于辅助导管在血管中导航的装置和方法
公开(公告)号：US20050288577A1
公开(公告)日：2005-12-29
申请号：US10536843
申请日：2003-11-27
申请人： Juergen Weese
发明人： Juergen Weese
IPC分类号： A61B8/00 , A61B8/12 , G06T17/00 , G06T17/40 , A61B6/00
CPC分类号： A61B8/12 , A61B5/0066 , G06T19/00 , G06T2210/41
摘要： The invention relates to the assistance of the navigation of a catheter (1) in a vessel (2). A sequence of cross-sectional images of the portion of the vessel that is of interest is first obtained with the help of an intravascular ultrasound (IVUS) probe (3) and stored as a roadmap of the vessel. A cross-sectional image (10) that is obtained at the current position of the IVUS probe (3) can then be sorted to the position on the roadmap that is the best fit. A model (3′) of the probe, and a model (11′) of the instrument (a stent (11), for example) coupled to the probe, can be shown on a display (6) at the corresponding position on the roadmap.
摘要翻译：本发明涉及导管（1）在血管（2）中导航的辅助。首先通过血管内超声（IVUS）探针（3）的帮助首先获得感兴趣的血管部分的横截面图像序列，并存储为血管的路线图。在IVUS探头（3）的当前位置处获得的横截面图像（10）可以被分类到路线图上最适合的位置。耦合到探针的探针的模型（3'）和与仪器（例如支架）相连的模型（11'）可以在显示器（6）上显示在路线图

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