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71. 发明授权

US08842906B2 Body measurement 有权
标题翻译：身体测量
公开(公告)号：US08842906B2
公开(公告)日：2014-09-23
申请号：US13569504
申请日：2012-08-08
申请人： Eleanor Watson , David Evans
发明人： Eleanor Watson , David Evans
IPC分类号： G06K9/00
CPC分类号： G06K9/00 , G06T7/75 , G06T2207/10004 , G06T2207/20081 , G06T2207/30196
摘要： A method of generating three dimensional body data of a subject is described. The method includes capturing one or more images of the subject using a digital imaging device and generating three dimensional body data of the subject based on the one or more images.
摘要翻译：描述了一种产生受试者的三维身体数据的方法。该方法包括使用数字成像装置拍摄对象的一个或多个图像，并且基于一个或多个图像生成被摄体的三维体数据。

72. 发明申请

US20140216554A1 Dye-Sensitized Solar Cell with Energy-Donor Material Enhancement 审中-公开
标题翻译：染料敏化太阳能电池与能量供体材料增强
公开(公告)号：US20140216554A1
公开(公告)日：2014-08-07
申请号：US13762527
申请日：2013-02-08
申请人： Sean Vail , David Evans , Wei Pan
发明人： Sean Vail , David Evans , Wei Pan
IPC分类号： H01G9/20 , H01G9/00
CPC分类号： H01G9/2018 , H01G9/2031 , H01G9/2059 , H01L2251/305 , H01L2251/306 , Y02E10/542
摘要： A dye-sensitized solar cell (DSC) is provided with energy-donor enhancement. A transparent conductive oxide (TCO) film is formed overlying a transparent substrate, and an n-type semiconductor layer is formed overlying the TCO. The n-type semiconductor layer is exposed to a dissolved dye (D1) having optical absorbance local maximums at a first wavelength (A1) and second wavelength (A2), longer than the first wavelength. The n-type semiconductor layer is functionalized with the dye (D1), forming a sensitized n-type semiconductor layer. A redox electrolyte is added that includes a dissolved energy-donor material (ED1) in contact with the sensitized n-type semiconductor layer. The energy-donor material (ED1) is capable of non-radiative energy transfer to the dye (D1), which is capable of charge transfer to the n-type semiconductor. In one aspect, the dye (D1) is a metalloporphyrin, such as zinc porphyrin (ZnP), and the energy-donor material (ED1) includes a perylene-monoimide material or chemically modified perylene-monoimide material.
摘要翻译：对染料敏化太阳能电池（DSC）提供能量供体增强。在透明基板上形成透明导电氧化物（TCO）膜，形成覆盖在TCO上的n型半导体层。 n型半导体层暴露于比第一波长长的第一波长（A1）和第二波长（A2）处具有吸光度局部最大值的溶解染料（D1）。 n型半导体层用染料（D1）功能化，形成敏化的n型半导体层。加入氧化还原电解质，其包括与敏化的n型半导体层接触的溶解的能量给体材料（ED1）。能量供体材料（ED1）能够将非辐射能量转移到能够电荷转移到n型半导体的染料（D1）上。一方面，染料（D1）是金属卟啉，例如卟啉锌（ZnP），能量供体材料（ED1）包括苝单酰亚胺材料或化学改性的二萘嵌苯单酰亚胺材料。

73. 发明申请

US20130225655A1 Combinations of TGFBeta and COX-2 Inhibitors and Methods for Their Therapeutic Application 有权
标题翻译： TGFBeta和COX-2抑制剂的组合及其治疗应用的方法
公开(公告)号：US20130225655A1
公开(公告)日：2013-08-29
申请号：US13695073
申请日：2011-05-04
申请人： Patrick Y. Lu , Vera Simonenko , David Evans , John J. Xu
发明人： Patrick Y. Lu , Vera Simonenko , David Evans , John J. Xu
IPC分类号： A61K31/713 , C07H21/02 , A61K45/06
CPC分类号： A61K31/713 , A61K45/06 , C07H21/02 , C12N15/113 , C12N15/1136 , C12N15/1137 , C12N2310/14 , C12N2320/11 , C12N2320/31 , C12Y114/99001
摘要： The present invention provides compositions and methods for using combinations of TGFβ1 and Cox-2 inhibitors and TGFβ1 and Hoxb13 inhibitors for the treatment of various medical conditions, including skin scaring due to trauma wounds and surgery, corneal and retina scaring due to injury and surgery, internal organ scaring due to injury and surgery, heart tissue scaring due to heart attack and surgery, and lung, liver, and kidney fibrosis due to inflammation and injury. One example is to use siRNA inhibitors to silence TGFβ1 and Cox-2 at the same time, resulting in significant less scar formation.
摘要翻译：本发明提供了使用TGFbeta1和Cox-2抑制剂和TGFbeta1和Hoxb13抑制剂的组合的组合物和方法，用于治疗各种医疗状况，包括由创伤伤口和手术引起的皮肤灼伤，由于损伤和手术引起的角膜和视网膜的惊吓，由于受伤和手术引起的内部器官惊吓，心脏病发作和手术引起的心脏组织惊厥，以及炎症和损伤引起的肺，肝，肾纤维化。一个实例是使用siRNA抑制剂同时沉默TGFbeta1和Cox-2，导致显着较少的瘢痕形成。

74. 发明授权

US08435779B2 Process for producing a virus-inactivated thrombin preparation 有权
标题翻译：用于生产病毒灭活的凝血酶制剂的方法
公开(公告)号：US08435779B2
公开(公告)日：2013-05-07
申请号：US10520457
申请日：2003-07-07
申请人： Caroline Connolly , Christopher Hardway , David Evans , Peter Feldman
发明人： Caroline Connolly , Christopher Hardway , David Evans , Peter Feldman
IPC分类号： C12N9/74
CPC分类号： C12N9/6429 , A61L2/0088 , C12Y304/21005
摘要： The present invention relates to processes for the preparation of virus inactivated thrombin, and to the products prepared by these processes.
摘要翻译：本发明涉及用于制备病毒灭活的凝血酶的方法以及通过这些方法制备的产品。

75. 发明申请

US20130102587A1 New Enzyme Inhibitor Compounds 有权
标题翻译：新型酶抑制剂化合物
公开(公告)号：US20130102587A1
公开(公告)日：2013-04-25
申请号：US13634732
申请日：2011-03-14
申请人： David Evans , Allison Carley , Alison Stewart , Michael Higginbottom , Edward Savory , Iain Simpson , Marianne Nilsson , Martin Haraldsson , Erik Nordling , Tobias Koolmeister
发明人： David Evans , Allison Carley , Alison Stewart , Michael Higginbottom , Edward Savory , Iain Simpson , Marianne Nilsson , Martin Haraldsson , Erik Nordling , Tobias Koolmeister
IPC分类号： C07D471/04 , C07D491/08 , C07D487/04
CPC分类号： C07D471/04 , C07D487/04 , C07D491/08 , C07D498/08 , C07D519/00
摘要： Disclosed are compounds which inhibit SSAO enzyme activity. Also disclosed are pharmaceutical compositions comprising these compounds and the use of these compounds in the treatment or prevention of medical conditions wherein inhibition of SSAO activity is beneficial, such as inflammatory diseases, immune disorders and the inhibition of tumour growth.
摘要翻译：公开了抑制SSAO酶活性的化合物。还公开了包含这些化合物的药物组合物以及这些化合物在治疗或预防其中抑制SSAO活性有益的医学病症中的用途，例如炎性疾病，免疫疾病和抑制肿瘤生长。

76. 发明申请

US20120266738A1 MUSIC GAME IMPROVEMENTS 审中-公开
标题翻译：音乐游戏改进
公开(公告)号：US20120266738A1
公开(公告)日：2012-10-25
申请号：US13375015
申请日：2010-05-31
申请人： David Evans , Doug Hardy , Robert Wolf
发明人： David Evans , Doug Hardy , Robert Wolf
IPC分类号： G10H7/00
CPC分类号： G09B15/00 , G10H1/368 , G10H2210/051 , G10H2210/091
摘要： The present invention provides a method of processing musical information. A user can perform a musical piece, using a real musical instrument (e.g. a guitar), which is received as audio input. The audio input is then assessed to determine whether it meets various quality standards—for example, whether the user played at the right pitch, at the right time, or at the right volume. If the audio input meets the standards, audio output is then provided of a professional performance of the musical piece, such that it sounds as if the user is performing the professional audio. The standards can be adjusted to different levels, depending on the user's skill on the musical instrument. At an easy level, low standards may be applied, such that even unskilled or beginner musicians can sound like a professional. For more skilled users, the standards may be more difficult to meet. If the user does not meet the quality standards, alternative audio output may be provided, indicating incorrect performance of the musical piece.
摘要翻译：本发明提供一种处理音乐信息的方法。用户可以使用作为音频输入接收的真实乐器（例如吉他）来执行音乐作品。然后评估音频输入以确定其是否符合各种质量标准 - 例如，用户是否以正确的音调，在正确的时间或以正确的音量播放。如果音频输入符合标准，则音乐输出将被提供给音乐作品的专业演奏，使得听起来好像用户正在执行专业音频。根据用户对乐器的技能，可以将标准调整到不同的级别。在一个简单的层面上，可能会采用低标准，即使是不熟练的或初学者的音乐家也可以听起来像一个专业人士。对于更熟练的用户，标准可能更难以满足。如果用户不符合质量标准，则可以提供替代音频输出，指示乐曲的不正确的表现。

77. 发明申请

US20120071540A1 Compositions and Methods Using siRNA Molecules and siRNA Cocktails for the Treatment of Breast Cancer 有权
标题翻译：使用siRNA分子和siRNA鸡尾酒治疗乳腺癌的组合物和方法
公开(公告)号：US20120071540A1
公开(公告)日：2012-03-22
申请号：US13141122
申请日：2009-12-31
申请人： Patrick Y. Lu , David Evans , Jun John Xu
发明人： Patrick Y. Lu , David Evans , Jun John Xu
IPC分类号： C07H21/02 , C12N5/09 , A61P35/04 , A61K31/7105
CPC分类号： C12N15/113 , C12N15/1135 , C12N15/1136 , C12N15/1137 , C12N15/1138 , C12N2310/11 , C12N2310/113 , C12N2310/17 , C12N2320/31 , C12N2320/32
摘要： The present invention provides small interfering RNA (siRNA) molecules, compositions containing the molecules, and methods of using the molecules and compositions to treat breast cancer. In one aspect, a multi-targeted siRNAi cocktail is disclosed. The siRNA molecules may be encapsulated in nanoparticles to further enhance their anti-cancer activity. The compositions may also be used in combination with other anti-cancer agents, such as bevacizumab.
摘要翻译：本发明提供小干扰RNA（siRNA）分子，含有该分子的组合物，以及使用该分子和组合物治疗乳腺癌的方法。一方面，公开了一种多靶向siRNAi混合物。 siRNA分子可以包封在纳米颗粒中以进一步增强其抗癌活性。组合物也可以与其它抗癌剂如贝伐珠单抗联合使用。

78. 发明申请

US20120015899A1 MODIFIED PLANT VIRUS PARTICLES AND USES THEREFOR 审中-公开
标题翻译：改良植物病毒颗粒及其用途
公开(公告)号：US20120015899A1
公开(公告)日：2012-01-19
申请号：US13125482
申请日：2009-10-25
申请人： George Lomonossoff , David Evans , Elisabet de los Pinos , Frank Sainsbury
发明人： George Lomonossoff , David Evans , Elisabet de los Pinos , Frank Sainsbury
IPC分类号： A61K31/7068 , C12N1/19 , C12N1/21 , A61P35/00 , C12N5/07
CPC分类号： C07K14/005 , A61K48/00 , C07K2319/85 , C12N7/00 , C12N2770/14023 , C12N2770/14042 , C12N2770/14045 , C12N2795/18123 , C12N2810/00 , C12N2810/10 , C12N2810/405
摘要： Aspects of the invention provide modified virus-like particles that are designed for therapeutic applications. In particular, aspects of the invention provide CCMV coat proteins that are modified to generate virus-like particles, including mosaic virus-like particles, that can package and/or deliver one or more diagnostic and/or therapeutic agents. The invention also provides methods for treating subjects with one or more modified virus-like particles.
摘要翻译：本发明的方面提供被设计用于治疗应用的经修饰的病毒样颗粒。特别地，本发明的方面提供了经修饰以产生病毒样颗粒（包括花叶病毒样颗粒）的CCMV外壳蛋白，其可包装和/或递送一种或多种诊断和/或治疗剂。本发明还提供了用一种或多种经修饰的病毒样颗粒治疗受试者的方法。

79. 发明申请

US20100137674A1 BRACHYTHERAPY TREATMENT OF THE SPINE WITH IRRADIATED IMPLANTS 审中-公开
标题翻译：用紫外线植入物进行脊柱的治疗
公开(公告)号：US20100137674A1
公开(公告)日：2010-06-03
申请号：US12626010
申请日：2009-11-25
申请人： David Evans , William Woodburn
发明人： David Evans , William Woodburn
IPC分类号： A61M36/12
CPC分类号： A61N5/1027 , A61F2/30744 , A61F2/44 , A61F2002/2821 , A61F2002/30405 , A61F2002/30495 , A61F2002/30507 , A61F2002/30551 , A61F2002/30601 , A61F2002/30668 , A61F2002/30785 , A61F2002/30843 , A61F2002/4475 , A61F2220/0025 , A61F2250/0001 , A61F2310/00017 , A61F2310/00023 , A61F2310/00179 , A61N2005/1024
摘要： A spinal implant configured to facilitate focused treatment of spinal tumors includes a plurality of irradiated implant seeds configured to concentrate the dosage and duration of radiation treatment of tumors.
摘要翻译：构造成促进脊柱肿瘤的聚焦治疗的脊柱植入物包括多个照射的种植体种子，其被配置为集中肿瘤的放射治疗的剂量和持续时间。

80. 发明申请

US20080232884A1 METHOD FOR PRINTING ONTO COLOURED SUBSTRATES 审中-公开
标题翻译：打印到彩色基板上的方法
公开(公告)号：US20080232884A1
公开(公告)日：2008-09-25
申请号：US12021771
申请日：2008-01-29
申请人： Trevor SIMMONDS , Gordon Reynen , David Evans
发明人： Trevor SIMMONDS , Gordon Reynen , David Evans
IPC分类号： B41J11/44
CPC分类号： G06K15/02 , G06K15/021 , G06K2215/0082 , G06K2215/0094
摘要： A method for printing an electronic image comprising a plurality of pixels onto a substrate using a computer-assisted image processing system, said method comprising the step of using alpha channel information in combination with substrate color information to calculate the transparency level that needs to be applied to each pixel.
摘要翻译：一种使用计算机辅助图像处理系统将包括多个像素的电子图像打印到基板上的方法，所述方法包括与基底颜色信息结合使用α通道信息以计算需要应用的透明度水平的步骤到每个像素。

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