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71. 发明授权

US08346519B2 Chemical processing system 有权
标题翻译：化学处理系统
公开(公告)号：US08346519B2
公开(公告)日：2013-01-01
申请号：US12530328
申请日：2008-02-26
申请人： Qiying Yin , Nan Zhang
发明人： Qiying Yin , Nan Zhang
IPC分类号： G06G7/48
CPC分类号： B01J19/0033 , B01J2219/00243
摘要： A method of optimising a processing system comprising a plurality of apparatuses includes defining a system model indicative of a predetermined range of apparatus options within a processing system, constraints indicative of feasible interconnections between each apparatus and another apparatus, and parameters indicative of performance criteria associated with each apparatus. The system model is analysed with respect to predetermined criteria to determine a preferred arrangement of apparatuses within the processing system.A parameter relating to at least one apparatus is indicative of the availability and/or the reliability of the apparatus expressed as a function of time.
摘要翻译：优化包括多个设备的处理系统的方法包括定义指示处理系统内的设备选项的预定范围的系统模型，指示每个设备与另一设备之间的可行互连的约束，以及指示与每台设备根据预定标准分析系统模型，以确定处理系统内的装置的优选布置。与至少一个装置相关的参数表示作为时间的函数表示的装置的可用性和/或可靠性。

72. 发明申请

US20110164253A1 METHOD OF MODIFYING A SUBSTRATE FOR DEPOSITION OF CHARGED PARTICLES THEREON 审中-公开
标题翻译：修饰用于沉积其中的颗粒的基材的方法
公开(公告)号：US20110164253A1
公开(公告)日：2011-07-07
申请号：US12737626
申请日：2009-08-03
申请人： Xiaodong Zhou , Nan Zhang , Kai Yu Liu , Su Yin Oh , Jisheng Pan
发明人： Xiaodong Zhou , Nan Zhang , Kai Yu Liu , Su Yin Oh , Jisheng Pan
IPC分类号： G01N21/55 , C23C14/34 , C23C16/44 , B05D1/36 , C23C14/48 , B05D1/06 , B32B5/16 , B32B3/00 , B82Y99/00
CPC分类号： G01N21/554 , Y10T428/24372
摘要： A method of modifying a substrate for deposition of charged particles thereon, the method comprising the steps of: providing a substrate that is incapable of bonding to a polyelectrolyte coating that has a charge that is opposite to the charge of the particles that are to be deposited thereon; modifying the surface of the substrate to provide a layer of silicon thereon or therein; and coating the silicon layered surface of the substrate with the polyelectrolyte coating, the polyelectrolyte coating containing functional groups that are capable of forming bonds with said silicon layer and wherein said polyelectrolyte coating enables a substantially even distribution of said charged particles to be deposited thereon.
摘要翻译：一种修饰底物以沉积带电粒子的方法，所述方法包括以下步骤：提供不能与聚电解质涂层结合的基底，所述聚电解质涂层具有与要沉积的颗粒的电荷相反的电荷上; 改变衬底的表面以在其上或其中提供硅层; 以及用所述聚电解质涂层涂覆所述基底的所述硅层状表面，所述聚电解质涂层含有能够与所述硅层形成键的官能团，并且其中所述聚电解质涂层能够使所述带电粒子基本均匀地分布在其上。

73. 发明授权

US07964678B2 Catalyst for olefin polymerization and preparation thereof and polymerization process 有权
标题翻译：烯烃聚合催化剂及其制备方法和聚合方法
公开(公告)号：US07964678B2
公开(公告)日：2011-06-21
申请号：US11659621
申请日：2006-02-24
申请人： Licai Wang , Zhanxian Gao , Wei Li , Guotong Zheng , Qingxin Dong , Riping Liu , Xiaohuan Wang , Nan Zhang , Jingzhuang Wang , Shimian Cai
发明人： Licai Wang , Zhanxian Gao , Wei Li , Guotong Zheng , Qingxin Dong , Riping Liu , Xiaohuan Wang , Nan Zhang , Jingzhuang Wang , Shimian Cai
IPC分类号： C08K5/06
CPC分类号： C08F10/00 , B01J21/063 , B01J35/023 , B01J35/1019 , C08F110/06 , C08F4/6543 , C08F4/651 , C08F4/6545 , C08F2500/15 , C08F2500/18
摘要： The catalyst for olefin polymerization contains three components A, B and C. The component A is a solid catalyst containing titanium, magnesium, chlorine element and an internal electron donor, the internal electron donor consists of 1,4-diether [2,2′-dialkoxy-1,1′-biphenyl, 2,2′-dialkoxy-1,1′-binaphthalene, 10,10′-dialkoxy-9,9-biphenanthrene]and organic acid ester or 1,3-diether [9,9-bis(methoxymethyl)fluorine, 2,2-dialky 1-1,3-dimethoxypropane]; the component B is an organoaluminum compound; the component C is external electron donor-organic silicon compound or the 1,4 aromatic diether. The catalyst has high catalytic activity, and can be adjusted in the range from 40,000 to 150,000 gPP/gCat when used in propylene polymerization. The polymer made therefrom has isotactivity of 80 to 99 percent and the molecular weight distribution can be adjusted in a wide range. The invention provides a novel method for preparing the 1,4 aromatic diether.
摘要翻译：用于烯烃聚合的催化剂包含三种组分A，B和C.组分A是含有钛，镁，氯元素和内电子给体的固体催化剂，内电子给体由1,4-二醚[2,2' 二烷氧基-1,1'-联苯基，2,2'-二烷氧基-1,1'-联萘，10,10'-二烷氧基-9,9-联苯]和有机酸酯或1,3-二醚[ 9-二（甲氧基甲基）氟，2,2-二烷基1-1,3-二甲氧基丙烷]; 组分B是有机铝化合物; 组分C是外电子给体 - 有机硅化合物或1,4-芳族二醚。该催化剂具有高催化活性，当用于丙烯聚合时可以将其调节至40,000至150,000gPP / gCat。由其制备的聚合物具有80-99％的等规度，并且可以在宽范围内调节分子量分布。本发明提供了一种制备1,4芳族二醚的新方法。

74. 发明申请

US20110074426A1 Detector module for an emission tomography scanner 有权
标题翻译：用于发射断层扫描仪的检测器模块
公开(公告)号：US20110074426A1
公开(公告)日：2011-03-31
申请号：US12585867
申请日：2009-09-28
申请人： Matthias J. Schmand , Markus Vester , Nan Zhang
发明人： Matthias J. Schmand , Markus Vester , Nan Zhang
IPC分类号： G01T1/164 , G01T1/20 , G01V3/00
CPC分类号： A61B6/4411 , A61B5/0035 , A61B5/055 , A61B6/037 , A61B6/4417 , G01R33/481 , G01T1/1603 , G01T1/1644
摘要： An emission tomography detector module and an emission tomography scanner are disclosed. In at least one embodiment, the emission tomography detector modules includes a scintillator to capture an photon, the scintillator emitting a scintillating light on capturing the photon; a first type of solid-state photodetector to detect the scintillating light; and a second type of solid-state photodetector to detect the scintillating light, wherein the first type of solid-state photodetector and the second type of solid-state photodetector are different with respect to a detecting property.
摘要翻译：公开了一种发射断层摄影检测器模块和发射断层扫描仪。在至少一个实施例中，发射断层摄影检测器模块包括闪光体以捕获光子，闪烁体在捕获光子时发射闪烁光; 用于检测闪烁光的第一种类型的固态光电检测器; 以及用于检测闪烁光的第二类型的固态光电检测器，其中所述第一类型的固态光电检测器和所述第二类型的固态光电检测器相对于检测特性是不同的。

75. 发明申请

US20100066426A1 BASELINE RESTORE BASED ON DIODE STAR CONFIGURATION AND TRANSFORMER COUPLING 失效
标题翻译：基于二极管配置和变压器耦合的基线恢复
公开(公告)号：US20100066426A1
公开(公告)日：2010-03-18
申请号：US12558007
申请日：2009-09-11
申请人： Matthias J. Schmand , Nan Zhang
发明人： Matthias J. Schmand , Nan Zhang
IPC分类号： H03L5/00
CPC分类号： G01T1/248
摘要： A simple, low cost circuit with only passive components, and thus low power consumption, is provided for baseline restoration of an AC coupled signal. The circuit includes a passive network of diodes arranged in a star configuration and an RF-transformer. A differential signal strategy may be employed by including a differential amplifier at the input and output of the passive network.
摘要翻译：提供了一种简单的低成本电路，仅具有无源组件，因此具有低功耗，用于AC耦合信号的基线恢复。该电路包括以星形结构布置的二极管的无源网络和RF变压器。可以通过在无源网络的输入和输出处包括差分放大器来采用差分信号策略。

76. 发明申请

US20100065746A1 SYSTEMS AND METHODS FOR CALIBRATING A SILICON PHOTOMULTIPLIER-BASED POSITRON EMISSION TOMOGRAPHY SYSTEM 有权
标题翻译：用于校准基于硅光刻胶的POSITRON排放测量系统的系统和方法
公开(公告)号：US20100065746A1
公开(公告)日：2010-03-18
申请号：US12560054
申请日：2009-09-15
申请人： Ronald Grazioso , Debora Henseler , Nan Zhang
发明人： Ronald Grazioso , Debora Henseler , Nan Zhang
IPC分类号： G01T1/161 , G01T1/166
CPC分类号： G01T1/1644 , A61B6/037 , G01T1/1648
摘要： A representative positron emission tomography (PET) system includes a positron emission tomography detector having one or more silicon photomultipliers that output silicon photomultipliers signals. The PET system further includes a calibration system that is electrically coupled to the silicon photomultipliers. The calibration system determines a single photoelectron response of the silicon photomultipliers signals and adjusts a gain of the silicon photomultipliers based on the single photoelectron response.
摘要翻译：代表性的正电子发射断层摄影（PET）系统包括正电子发射断层摄影检测器，其具有输出硅光电倍增管信号的一个或多个硅光电倍增管。 PET系统还包括电耦合到硅光电倍增管的校准系统。校准系统确定硅光电倍增管信号的单个光电子响应，并且基于单个光电子响应调整硅光电倍增管的增益。

77. 发明申请

US20100061982A1 3-SUBSTITUTED-1H-INDOLE, 3-SUBSTITUTED-1H-PYRROLO[2,3-B]PYRIDINE AND 3-SUBSTITUTED-1H-PYRROLO[3,2-B]PYRIDINE COMPOUNDS, THEIR USE AS MTOR KINASE AND PI3 KINASE INHIBITORS, AND THEIR SYNTHESES 审中-公开
标题翻译： 3-取代的1H-吲哚，3-取代的1H-吡咯并[2,3-b]吡啶和3-取代的1H-吡咯[3,2-B]吡啶化合物，它们作为MTOR激酶和PI3激酶抑制剂，和他们的合成
公开(公告)号：US20100061982A1
公开(公告)日：2010-03-11
申请号：US12556833
申请日：2009-09-10
申请人： Semiramis Ayral-Kaloustian , Tarek Suhayl Mansour , Hwei-Ru Tsou , Nan Zhang , Aranapakam Mudumbai Venkatesan , Li Di , Edward Harvel Kerns
发明人： Semiramis Ayral-Kaloustian , Tarek Suhayl Mansour , Hwei-Ru Tsou , Nan Zhang , Aranapakam Mudumbai Venkatesan , Li Di , Edward Harvel Kerns
IPC分类号： A61K39/395 , C07D405/06 , A61K31/40 , C07D403/06 , A61K31/497 , C07D498/02 , A61K31/5386
CPC分类号： C07D407/06 , C07D471/04
摘要： The invention relates to 3-substituted-1H-indole, 3-substituted-1H-pyrrolo[2,3-b]pyridine, and 3-substituted-1H-pyrrolo[3,2-b]pyridine compounds of the Formula 1: or a pharmaceutically acceptable salt thereof, wherein the constituent variables are as defined herein, compositions comprising the compounds, and methods for making and using the compounds.
摘要翻译：本发明涉及式1的3-取代-1H-吲哚，3-取代-1H-吡咯并[2,3-b]吡啶和3-取代-1H-吡咯并[3,2-b]吡啶化合物：或其药学上可接受的盐，其中组成变量如本文所定义，包含该化合物的组合物，以及制备和使用该化合物的方法。

78. 发明申请

US20090298820A1 3-SUBSTITUTED-1H-PYRROLO[2,3-B]PYRIDINE AND 3-SUBSTITUTED-1H-PYRROLO[3,2-B]PYRIDINE COMPOUNDS, THEIR USE AS MTOR KINASE AND PI3 KINASE INHIBITORS, AND THEIR SYNTHESES 审中-公开
标题翻译： 3-取代的1H-吡咯并[2,3-b]吡啶和3-取代的1H-吡咯[3,2-B]吡啶化合物，它们作为MTOR激酶和PI3激酶抑制剂使用，以及它们的合成
公开(公告)号：US20090298820A1
公开(公告)日：2009-12-03
申请号：US12473658
申请日：2009-05-28
申请人： Hwei-Ru Tsou , Gary Harold Birnberg , Gloria Jean MacEwan , Semiramis Ayral-Kaloustian , Matthew Gregory Bursavich , Sabrina Lombardi , Nan Zhang , Adam Matthew Gilbert , George Theordore Grosu , Natasja Brooijmans , Thai Hiep Nguyen
发明人： Hwei-Ru Tsou , Gary Harold Birnberg , Gloria Jean MacEwan , Semiramis Ayral-Kaloustian , Matthew Gregory Bursavich , Sabrina Lombardi , Nan Zhang , Adam Matthew Gilbert , George Theordore Grosu , Natasja Brooijmans , Thai Hiep Nguyen
IPC分类号： A61K31/437 , A61K31/5375 , A61K31/5377 , A61K31/496 , C07D471/04 , A61P35/00 , C07D498/08 , A61P29/00 , A61P17/00 , A61P19/00
CPC分类号： C07D471/04 , C07D498/08
摘要： The invention relates to 3-substituted-1H-pyrrolo[2,3-b]pyridine, and 3-substituted-1H-pyrrolo[3,2-b]pyridine compounds of the Formula 1: or a pharmaceutically acceptable salt thereof, wherein the constituent variables are as defined herein, compositions comprising the compounds, and methods for making and using the compounds.
摘要翻译：本发明涉及式1的3-取代-1H-吡咯并[2,3-b]吡啶和3-取代-1H-吡咯并[3,2-b]吡啶化合物或其药学上可接受的盐，其中组成变量如本文所定义，包含该化合物的组合物，以及制备和使用该化合物的方法。

79. 发明授权

US07507739B2 6-[(substituted)phenyl]triazolopyrimidines as anticancer agents 失效
标题翻译： 6 - [（取代的）苯基]三唑并嘧啶作为抗癌剂
公开(公告)号：US07507739B2
公开(公告)日：2009-03-24
申请号：US10950543
申请日：2004-09-24
申请人： Nan Zhang , Semiramis Ayral-Kaloustian , Thai Nguyen , Yanzhong Wu , Wei Tong
发明人： Nan Zhang , Semiramis Ayral-Kaloustian , Thai Nguyen , Yanzhong Wu , Wei Tong
IPC分类号： C07D487/04 , A61K31/519 , A61P35/04
CPC分类号： C07D487/04
摘要： This invention relates to certain 6-[(substituted)phenyl]triazolopyrimidine compounds or pharmaceutically acceptable salts thereof, and compositions containing said compounds or pharmaceutically acceptable salts thereof, wherein said compounds are anti-cancer agents useful for the treatment of cancer in mammals. This invention further relates to a method of treating or inhibiting the growth of cancerous tumor cells and associated diseases in a mammal and further provides a method for the treatment or prevention of cancerous tumors that express multiple drug resistance (MDR) or are resistant because of MDR, in a mammal in need thereof which method comprises administering to said mammal an effective amount of said compounds or pharmaceutically acceptable salts thereof. The present invention relates to a method of treating or inhibiting the growth of cancerous tumor cells and associated diseases in a mammal in need thereof by promotion of microtubule polymerization which comprises administering to said mammal an effective amount of said compounds and pharmaceutically acceptable salts thereof.
摘要翻译：本发明涉及某些6 - [（取代的）苯基]三唑并嘧啶化合物或其药学上可接受的盐，以及含有所述化合物或其药学上可接受的盐的组合物，其中所述化合物是可用于治疗哺乳动物癌症的抗癌剂。本发明还涉及治疗或抑制哺乳动物中癌性肿瘤细胞和相关疾病的生长的方法，并进一步提供了治疗或预防表达多重耐药性（MDR）或耐多药耐药性的癌性肿瘤的方法在有需要的哺乳动物中，所述方法包括向所述哺乳动物施用有效量的所述化合物或其药学上可接受的盐。本发明涉及通过促进微管聚合来治疗或抑制有需要的哺乳动物中癌性肿瘤细胞和相关疾病的生长的方法，其包括对所述哺乳动物施用有效量的所述化合物及其药学上可接受的盐。

80. 发明申请

US20080290282A1 Concurrent DC-Coupled Anode and Dynode Readout Scheme For PET Block Detectors 有权
标题翻译：用于PET块检测器的并行DC耦合阳极和Dynode读出方案
公开(公告)号：US20080290282A1
公开(公告)日：2008-11-27
申请号：US11753067
申请日：2007-05-24
申请人： Nan Zhang , Matthias J. Schmand , Niraj K. Doshi , Michael D. Loope
发明人： Nan Zhang , Matthias J. Schmand , Niraj K. Doshi , Michael D. Loope
IPC分类号： G01T1/20
CPC分类号： G01T1/1642 , G01T1/208
摘要： A scintillation detector including one or more photomultiplier tubes, a scintillation block optically attached to the photomultiplier tubes, and a DC-coupled bleeder circuit combining outputs of dynodes of the photomultipliers to provide a DC-coupled dynode output together with a DC-coupled anode output of the photomultiplier tubes. The DC-coupled bleeder circuit includes a RF transformer. A positive high voltage supply also can be used together with a DC-coupled bleeder circuit for the anode outputs.
摘要翻译：闪烁检测器，包括一个或多个光电倍增管，与光电倍增管光学连接的闪烁块，以及组合光电倍增管的倍增电极输出的DC耦合泄放电路，以提供DC耦合的倍增电极输出以及直流耦合的阳极输出的光电倍增管。直流耦合放电电路包括RF变压器。阳极高压电源也可以与阳极输出的直流耦合泄放电路一起使用。

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