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71. 发明授权

US06601051B1 Neural systems with range reducers and/or extenders 失效
标题翻译：带范围减速器和/或增量器的神经系统
公开(公告)号：US06601051B1
公开(公告)日：2003-07-29
申请号：US08893782
申请日：1997-07-11
申请人： James Ting-Ho Lo , Lei Yu
发明人： James Ting-Ho Lo , Lei Yu
IPC分类号： G06F1518
CPC分类号： H03H21/0012 , G06N3/0445 , G06N3/084 , H03H2222/04
摘要： A neural system is disclosed for processing an exogenous input process to produce a good outward output process with respect to a performance criterion, even if the range of one or both of these processes is necessarily large and/or keeps necessarily expanding during the operation of the neural system. The disclosed neural system comprises a recurrent neural network (RNN) and at least one range extender or reducer, each of which is a dynamic transformer. A range reducer transforms dynamically at least one component of the exogenous input process into inputs to at least one input neuron of said RNN. A range extender transforms dynamically outputs of at least one output neuron of said RNN into at least one component of the outward output process. There are many types of range extender and reducer, which have different degrees of effectiveness and computational costs. For a neural system under design, the types of range extenders and/or reducers are selected jointly with the architecture of the RNN in consideration of the neural system's processing performance with respect to the mentioned performance criterion, the RNN's size and the computational cost of selected range extenders and reducers so as to maximize the cost effectiveness of the neural system.
摘要翻译：公开了一种用于处理外部输入过程以产生相对于性能标准的良好的向外输出过程的神经系统，即使这些过程中的一个或两个的范围必然很大和/或在操作期间必然扩大神经系统。所公开的神经系统包括循环神经网络（RNN）和至少一个范围扩展器或减速器，每个延伸器或减速器都是动态变压器。范围缩减器将动态地将外部输入过程的至少一个分量变换成对所述RNN的至少一个输入神经元的输入。范围扩展器将所述RNN的至少一个输出神经元的动态输出转换成向外输出过程的至少一个分量。范围扩展器和减速器有许多种类，具有不同程度的有效性和计算成本。对于设计中的神经系统，考虑到关于上述性能标准的神经系统的处理性能，RNN的尺寸和所选择的计算成本，扩展器和/或减速器的类型与RNN的架构联合选择扩展器和减速器，以最大化神经系统的成本效益。

72. 发明授权

US06335168B1 Alleles of the human mu opioid receptor and diagnostic methods based thereon 失效
标题翻译：人类μ阿片受体的等位基因及其诊断方法
公开(公告)号：US06335168B1
公开(公告)日：2002-01-01
申请号：US09351198
申请日：1999-07-09
申请人： Mary Jeanne Kreek , Karl Steven LaForge , Lei Yu , Jay A. Tischfield
发明人： Mary Jeanne Kreek , Karl Steven LaForge , Lei Yu , Jay A. Tischfield
IPC分类号： C12Q168
CPC分类号： C12Q1/6883 , C12Q2600/156
摘要： Provided herein are variant alleles of a gene encoding a mu opioid receptor, along with cloning vectors for replicating such variant alleles, expressing vectors for expressing the variant alleles to produce variant mu opioid receptors, and antibodies to such variant receptors. Also disclosed are binding characteristics of such variant receptors regarding binding to opioid ligands, and the using of such binding characteristics to diagnose a subjects susceptibility to pain, susceptibility to an addictive disease, selecting an appropriate pain reliever along with a therapeutically effective amount of the reliever to administer to a subject suffering from pain. In addition, diagnostic methods for diagnosing a disease or disorder such as infertility, constipation, diarrhea, decreased immune response relative to a standard, and decreased ability to withstand stress relative to a standard, along with commercial kits for diagnosing such diseases or disorders. Furthermore, the invention is also directed to identification of targeted prevention methods, early therapeutic intervention, and improved treatment of opioid addiction, infertility, constipation, diarrhea, impaired immune responsiveness, and stress.
摘要翻译：本文提供了编码μ阿片受体的基因的变异等位基因，以及用于复制这种变异等位基因的克隆载体，表达用于表达变体等位基因以产生变体μ阿片样物质受体的载体，以及针对这种变体受体的抗体。还公开了这样的变体受体关于结合阿片样物质配体的结合特征，以及使用这种结合特征来诊断受试者对疼痛的敏感性，对成瘾性疾病的易感性，选择适当的止痛药以及治疗有效量的缓解剂给予痛苦的受试者。此外，用于诊断疾病或病症的诊断方法，例如不育症，便秘，腹泻，相对于标准物的免疫应答降低，以及相对于标准物承受应力的能力降低，以及用于诊断这种疾病或病症的商业试剂盒。此外，本发明还涉及确定靶向预防方法，早期治疗干预和改善阿片样物质成瘾，不育症，便秘，腹泻，免疫应答受损和应激的治疗。

73. 发明申请

US20230122682A1 Valve piston pump body device 有权
公开(公告)号：US20230122682A1
公开(公告)日：2023-04-20
申请号：US18066993
申请日：2022-12-15
申请人： Lei Yu
发明人： Lei Yu
IPC分类号： F04B19/04 , F04B17/00 , F04B53/14 , F04B49/12
摘要： A valve piston pump body device of water flosser includes a front bracket shell equipped with a back bracket shell. A pump body is installed at the middle-upper end of the cavity between the front bracket shell and the back bracket shell. A motor is installed at the middle-lower end of the cavity between the front bracket shell and the back bracket shell. The rotating shaft at the upper end of the motor is equipped with motor teeth. A first metal shaft is arranged in the hole of the cavity between the front bracket shell and the back bracket shell. A driving gear is installed on the first metal shaft and the driving gear and the motor teeth are mutually engaged. A one-way valve piston device is used.

74. 发明授权

US11324575B2 Pump body of oral irrigator 有权
公开(公告)号：US11324575B2
公开(公告)日：2022-05-10
申请号：US17095776
申请日：2020-11-12
申请人： Lei Yu
发明人： Lei Yu
IPC分类号： A61C17/02
摘要： A pump body of an oral irrigator includes a mount, a motor disposed at a rear end away from the mount, a pinion disposed on a shaft of the motor, an annular gear disposed on a shaft member to mesh with the pinion, a cam disposed in the annular gear and adjacent to one side, a linkage secured to the cam, front and rear plungers disposed on a front end of the linkage, and a cylindrical tube disposed on the plungers in the mount. The rotation of the cam only allows the linkage to repetitively move in a back-and-forth linear motion. Wear between the plungers and the cylindrical tube is decreased to a minimum and leakage is prevented.

75. 发明申请

US20210059801A1 Portable oral irrigator 有权
公开(公告)号：US20210059801A1
公开(公告)日：2021-03-04
申请号：US17095778
申请日：2020-11-12
申请人： Lei Yu
发明人： Lei Yu
IPC分类号： A61C17/02
摘要： A portable oral irrigator includes a nozzle, a handle, an outer water container and an inner water container. The nozzle is at an upper end of the portable oral irrigator. The handle is below the nozzle. The outer water container is below the handle. The inner water container is below the outer water container. A sealing ring is at a bottom of the inner water container for sealing the inner water container. An annular silicone sealing member is at a joining portion of the outer water container and the inner water container. A gasket is between the outer water container and the handle. An air passable silicone seal is on the gasket. With provision of the air passable silicone seal, a raised bottom of the air passable silicone seal contracts to close its cross-shaped opening due to water pressure in the outer water container, thereby preventing leakage.

76. 发明申请

US20210059785A1 Portable oral irrigator 有权
公开(公告)号：US20210059785A1
公开(公告)日：2021-03-04
申请号：US17095780
申请日：2020-11-12
申请人： Lei Yu
发明人： Lei Yu
IPC分类号： A61C1/00 , A61C1/08 , A61C17/02
摘要： A portable oral irrigator includes a charging seat assembly, a water container assembly, a housing assembly and a pump assembly. The charging seat assembly includes a charging seat base, a transparent charging seat member on the charging seat base, a first control board in the charging seat base, a first light guide line in the transparent charging seat member, a second light guide line in the charging seat base, a charging seat cover on the transparent charging seat member, and a charging socket projecting out of the charging seat cover. With provision of the charging seat assembly, the water container assembly, the housing assembly and the pump assembly, the pump unit draws water from the water container body and exits the water through the nozzle. The first and second light guide lines and the light guide strip emit light to indicate a current state of the oral irrigator.

77. 发明授权

US09143356B2 Method and system for email processing 有权
标题翻译：电子邮件处理方法和系统
公开(公告)号：US09143356B2
公开(公告)日：2015-09-22
申请号：US12826040
申请日：2010-06-29
申请人： Xin Yan Wei , Lei Yu , Wei Li , Xiang Chen
发明人： Xin Yan Wei , Lei Yu , Wei Li , Xiang Chen
IPC分类号： G06F15/16 , H04L12/58
CPC分类号： H04L12/58 , H04L51/00
摘要： An Email processing method and system comprising in response to obtaining an Email, parsing contents of the Email to obtain an Email subject identifier of the Email, at least one new interaction record, and interaction information corresponding to the at least one new interaction record; determining whether there is a merged Email, which has a merge Email subject identifier matching a subject identifier of the Email, and conforms to a predefined interaction content structure comprising at least one interaction record divided by interaction relationship of contents; and in response to that the determination result is yes, merging the at least one new interaction record of the Email into the merged Email to generate a new merged Email based on the interaction information corresponding to the at least one new interaction record.
摘要翻译：一种电子邮件处理方法和系统，包括响应于获得电子邮件，解析电子邮件的内容以获得电子邮件的电子邮件主题标识符，至少一个新的交互记录以及对应于该至少一个新交互记录的交互信息; 确定是否存在合并的电子邮件，其具有与电子邮件的主题标识符相匹配的合并电子邮件主题标识符，并且符合包含至少一个交互记录的预定交互内容结构，除以内容的交互关系; 并且响应于此，所述确定结果为是，将所述Email的所述至少一个新的交互记录合并到所述合并的电子邮件中，以基于与所述至少一个新的交互记录相对应的交互信息生成新的合并的电子邮件。

78. 发明申请

US20130010643A1 Method and apparatus for loop path search in mesh network 审中-公开
标题翻译：网状网络中循环路径搜索的方法和装置
公开(公告)号：US20130010643A1
公开(公告)日：2013-01-10
申请号：US13582292
申请日：2010-10-13
申请人： Lei Yu
发明人： Lei Yu
IPC分类号： H04L12/28
CPC分类号： H04W40/02 , H04L45/18
摘要： The present invention discloses a method and apparatus for loop path search in a mesh network, comprising: a network side searching for all nodes adjacent to node v1 in the mesh network, and deleting all edges formed by node v1 and nodes directly connected to node v1 in the mesh network; the network side performing calculation for all obtained nodes adjacent to node v1 through a K shortest path algorithm to obtain all paths between all nodes adjacent to node v1; and the network side traversing all obtained paths between all nodes adjacent to node v1, and adding node v1 at start and termination of each path to finish search for all loop paths of node v1 in the Mesh network. With the present invention, the problem of low loop path search efficiency existed in the conventional method is solved, and the loop path search efficiency is improved.
摘要翻译：本发明公开了一种网状网络环路搜索的方法和装置，包括：网络侧搜索网状网络中与节点v1相邻的所有节点，并删除由节点v1形成的所有边缘，直接连接到节点v1的节点在网状网络中; 网络侧通过K最短路径算法对与节点v1相邻的所有获得的节点执行计算，以获得与节点v1相邻的所有节点之间的所有路径; 并且网络侧遍历与节点v1相邻的所有节点之间的所有获取的路径，并且在每个路径的开始和结束处添加节点v1以完成对Mesh网络中节点v1的所有环路径的搜索。利用本发明，解决了传统方法中存在的低循环路径搜索效率的问题，并提高了循环路径搜索效率。

79. 发明申请

US20120245216A1 COMPOSITIONS AND METHODS FOR TREATMENT OF NEUROPATHIC PAIN 有权
标题翻译：治疗神经痛疼痛的组合物和方法
公开(公告)号：US20120245216A1
公开(公告)日：2012-09-27
申请号：US13393399
申请日：2010-09-02
申请人： Lei Yu , Ning Guo , Yu-Qui Zhang , Zhi-Qi Zhao , Naihe Jing
发明人： Lei Yu , Ning Guo , Yu-Qui Zhang , Zhi-Qi Zhao , Naihe Jing
IPC分类号： A61K31/7088 , C12Q1/68 , G01N33/68 , G01N33/53 , A61P29/00 , A61P25/00
CPC分类号： G01N33/566 , C07K14/47 , C12N15/113 , C12N2310/11 , G01N2500/04 , G01N2800/2842
摘要： The present invention relates to compounds, compositions, methods, systems and kits for treating neuropathic pain regulated by SIP30. The present invention provides SIP30 antagonists for the treatment of neuropathic pain.
摘要翻译：本发明涉及用于治疗由SIP30调节的神经性疼痛的化合物，组合物，方法，系统和试剂盒。本发明提供了用于治疗神经性疼痛的SIP30拮抗剂。

80. 发明申请

US20110013623A1 METHOD AND SYSTEM OF CIRCUIT SWITCHED DOMAIN PAGE REALIZATION, METHOD OF SERVICE REALIZATION 有权
标题翻译：电路切换域实现的方法和系统，服务实现方法
公开(公告)号：US20110013623A1
公开(公告)日：2011-01-20
申请号：US12865952
申请日：2009-01-24
申请人： Ying Hu , Zhiming Yu , Jinguo Zhu , Lei Yu , Liping Geng
发明人： Ying Hu , Zhiming Yu , Jinguo Zhu , Lei Yu , Liping Geng
IPC分类号： H04L12/66
CPC分类号： H04W68/12 , H04W8/06 , H04W60/005
摘要： A method and a system for implementing CS domain paging are disclosed, applied in scenarios of performing CS domain paging for a called UE after ISR function is introduced in PS domain, and comprising: MSC/VLR only storing one Gs association; during CS domain paging, MSC/VLR sending a CS domain paging request message to the PS domain network element recorded in the Gs association in the MSC/VLR; after receiving the message, the PS domain network element initiating one or two CS domain paging procedures in the PS domain to transmit the CS domain paging to the called UE; or sending a paging response to the MSC/VLR directly without initiating CS domain paging. A method for transferring service information is also disclosed, applied in the scenarios that ISR function is activated in PS domain, and comprising: transmitting service message(s) between the ISR-associated PS domain network elements serving the UE to implement transfer of service information.
摘要翻译：公开了一种用于实现CS域寻呼的方法和系统，其应用于在PS域中引入ISR功能之后为被叫UE执行CS域寻呼的场景，并且包括：MSC / VLR仅存储一个Gs关联; 在CS域寻呼期间，MSC / VLR向MSC / VLR中的Gs关联中记录的PS域网元发送CS域寻呼请求消息; 接收到该消息后，PS域网单元在PS域中发起一个或两个CS域寻呼过程，将CS域寻呼发送给被叫UE; 或直接向MSC / VLR发送寻呼响应而不发起CS域寻呼。还公开了一种用于传送服务信息的方法，其应用于在PS域中激活ISR功能的场景，包括：在服务于UE的ISR相关联的PS域网元之间传送业务消息，实现业务信息的传输。

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