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71. 发明授权

US6117106A Perfusion catheter with coil supported inner tubular member 有权
标题翻译：灌注导管带线圈支撑内管状构件
公开(公告)号：US6117106A
公开(公告)日：2000-09-12
申请号：US419614
申请日：1999-10-14
申请人： Lawrence D. Wasicek , Yen Chan , Mina W. B. Chow , Ketan P. Muni , Bozena Z. Maslanka
发明人： Lawrence D. Wasicek , Yen Chan , Mina W. B. Chow , Ketan P. Muni , Bozena Z. Maslanka
IPC分类号： A61M25/00 , A61M29/02
CPC分类号： A61M25/104 , A61M25/0052 , A61M2025/0004 , A61M2025/1079 , A61M2025/1097 , A61M25/0053
摘要： A perfusion dilatation catheter is disclosed which has an improved distal catheter shaft portion with a tubular member extending within the balloon provided with an expanded coil support incorporated within the wall of the tubular member. The coil is preferably closer to the inner surface than the outer surface of the tubular member. Also disclosed are improved catheter shaft sections in a perfusion portion proximal to the balloon, one with a reinforced inflation tube depending into the guidewire lumen and another having three separate lumens, a central guidewire lumen and a pair of inflation lumens on opposing sides of the tubular structure defining the guidewire lumen.
摘要翻译：公开了一种灌注扩张导管，其具有改进的远端导管轴部分，其具有在球囊内延伸的管状构件，该管状构件设置有并入管状构件的壁内的扩张的线圈支架。线圈优选地比管状构件的外表面更靠近内表面。还公开了在靠近气囊的灌注部分中的改进的导管轴部分，一个具有依赖于导丝管腔的增强的充气管，另一个具有三个独立的腔，中心导丝腔和一对在管的相对侧上的充气腔限定导丝管腔的结构。

72. 发明授权

US5849846A Balloons for medical catheters 失效
标题翻译：医用导管气球
公开(公告)号：US5849846A
公开(公告)日：1998-12-15
申请号：US476101
申请日：1995-06-06
申请人： Ziyun Chen , Tai C. Cheng , Jeong S. Lee , Ketan P. Muni , Udayan Patel , Robert P. Saltman
发明人： Ziyun Chen , Tai C. Cheng , Jeong S. Lee , Ketan P. Muni , Udayan Patel , Robert P. Saltman
IPC分类号： A61L29/00 , A61L29/04 , A61M25/00 , A61M25/16 , C08L23/02 , C08L67/00 , C08L67/02 , C08L77/00 , A61M25/10 , A61M29/02
CPC分类号： A61L29/049 , A61M25/1029 , C08L67/02 , A61M2025/1031 , A61M25/0009
摘要： A catheter and/or balloon for a medical catheter is formed from a blend of polymeric components, including a first crystalline polymeric component and a second softening polymeric component. The polymeric material can also include a third compatibilizing agent to facilitate blending the first two polymeric components together. The first polymeric component can be a polyester or a polyamide, and the second polymeric component can be a polyolefin, or an ethylene copolymer. The third polymeric component is preferably an ethylene copolymer containing a reactive group that forms a covalent bond with the first polymeric component. The polymeric material forming the balloon or catheter also can include a catalyst to catalyze a reaction between the compatibilizing ethylene copolymer and the second polymer component. The second, softening polymeric component can also include a silane coupling agent, to provide a reactive softening copolymer that bonds with the first strong polymeric component, to provide increased flexibility of catheters and balloons formed from the polymeric components. The properties of the balloon and catheter formed from the polymeric material can be enhanced by crosslinking by irradiation of the polymeric material.
摘要翻译：用于医疗导管的导管和/或气囊由聚合物组分的混合物形成，包括第一结晶聚合物组分和第二软化聚合物组分。聚合物材料还可以包括第三相容剂以便于将前两个聚合物组分共混在一起。第一聚合物组分可以是聚酯或聚酰胺，第二聚合物组分可以是聚烯烃或乙烯共聚物。第三聚合物组分优选是含有与第一聚合物组分形成共价键的反应性基团的乙烯共聚物。形成气囊或导管的聚合物材料还可以包括催化剂，以催化相容性乙烯共聚物和第二聚合物组分之间的反应。第二软化聚合物组分还可以包括硅烷偶联剂，以提供与第一强聚合物组分键合的反应性软化共聚物，以提供由聚合物组分形成的导管和气囊的增加的柔性。由聚合物材料形成的球囊和导管的性质可以通过聚合材料的照射交联来增强。

73. 发明授权

US5348537A Catheter with intraluminal sealing element 失效
标题翻译：导管内腔内密封元件
公开(公告)号：US5348537A
公开(公告)日：1994-09-20
申请号：US913859
申请日：1992-07-15
申请人： Steven P. Wiesner , Ketan P. Muni
发明人： Steven P. Wiesner , Ketan P. Muni
IPC分类号： A61M25/00 , A61M29/02
CPC分类号： A61M25/0075 , A61M25/104 , A61M2025/0063
摘要： A sealing element for dilatation and other inflatable catheters which is formed of a polymer matrix having a bearing surface and having incorporated, at least in the portion of the matrix forming the bearing surface, a lubricous material which swells upon contact with an aqueous based liquid. The bearing surface is adapted to engage the surface of a movable member such as a guidewire when the bearing surface expands from contact with aqueous based liquid. This engagement seals the interface between the movable member and the sealing element and prevents the passage of significant amounts of liquid through the interface between these elements.
摘要翻译：用于膨胀的密封元件和其它可充气导管，其由具有支承表面的聚合物基体形成，并且至少在形成支承表面的基质部分中并入润滑材料，所述润滑材料在与基于水的液体接触时溶胀。当轴承表面与基于水的液体的接触膨胀时，支承表面适于接合诸如导丝的可移动部件的表面。该接合密封可移动构件和密封元件之间的界面，并防止大量液体通过这些元件之间的界面。

74. 发明授权

US09095364B2 Device and method for dilating an airway stenosis 有权
标题翻译：扩张气道狭窄的装置和方法
公开(公告)号：US09095364B2
公开(公告)日：2015-08-04
申请号：US13551849
申请日：2012-07-18
申请人： Ketan P. Muni , Randy S. Chan , Sivette Lam , Shrirang V. Ranade
发明人： Ketan P. Muni , Randy S. Chan , Sivette Lam , Shrirang V. Ranade
IPC分类号： A61B5/05 , A61B17/24 , A61M16/04 , A61M29/02 , A61B6/12 , A61M16/00 , A61M16/08 , A61M25/00
CPC分类号： A61B17/24 , A61B6/12 , A61M16/0057 , A61M16/04 , A61M16/0438 , A61M16/044 , A61M16/0445 , A61M16/0463 , A61M16/0486 , A61M16/0488 , A61M16/0816 , A61M25/0026 , A61M25/007 , A61M29/02 , A61M2205/32 , A61M2205/6081
摘要： A medical device and a system and for dilating a stenotic airway of a patient are described. The medical device comprises a proximal end, a distal end, and a shaft system having an inflation lumen and a ventilation lumen the proximal end. The shaft system has a proximal shaft section and a distal shaft section. An inflatable balloon is attached to the distal shaft section in a position that is proximal to the distal end. The ventilating tip is distal to the balloon on the distal shaft section and has one or more radially facing openings. A method for treating a stenotic airway includes inserting the medical device into a patient's airway, and dilating and ventilating the airway.
摘要翻译：描述了医疗装置和系统，并且用于扩张患者的狭窄气道。医疗装置包括近端，远端以及具有充气腔和远端的通气腔的轴系。轴系具有近轴部分和远侧轴部分。可膨胀的气球在远端轴部分附近位于远端的位置。通气尖端在远侧轴部分上的球囊的远侧，并且具有一个或多个径向面对的开口。用于治疗狭窄性气道的方法包括将医疗装置插入患者的气道中，并使气道扩张和通气。

75. 发明申请

US20130184568A1 DEVICE AND METHOD FOR DILATING AN AIRWAY STENOSIS 有权
标题翻译：用于泄漏空中运动障碍的装置和方法
公开(公告)号：US20130184568A1
公开(公告)日：2013-07-18
申请号：US13551849
申请日：2012-07-18
申请人： Ketan P. Muni , Randy S. Chan , Sivette Lam , Shrirang V. Ranade
发明人： Ketan P. Muni , Randy S. Chan , Sivette Lam , Shrirang V. Ranade
IPC分类号： A61B17/24 , A61M16/08 , A61M16/00 , A61M16/04 , A61B6/12
CPC分类号： A61B17/24 , A61B6/12 , A61M16/0057 , A61M16/04 , A61M16/0438 , A61M16/044 , A61M16/0445 , A61M16/0463 , A61M16/0486 , A61M16/0488 , A61M16/0816 , A61M25/0026 , A61M25/007 , A61M29/02 , A61M2205/32 , A61M2205/6081
摘要： A medical device and a system and for dilating a stenotic airway of a patient are described. The medical device comprises a proximal end, a distal end, and a shaft system having an inflation lumen and a ventilation lumen the proximal end. The shaft system has a proximal shaft section and a distal shaft section. An inflatable balloon is attached to the distal shaft section in a position that is proximal to the distal end. The ventilating tip is distal to the balloon on the distal shaft section and has one or more radially facing openings. A method for treating a stenotic airway includes inserting the medical device into a patient's airway, and dilating and ventilating the airway.
摘要翻译：描述了医疗装置和系统，并且用于扩张患者的狭窄气道。医疗装置包括近端，远端以及具有充气腔和远端的通气腔的轴系。轴系具有近轴部分和远侧轴部分。可膨胀的气球在远端轴部分附近位于远端的位置。通气尖端在远侧轴部分上的球囊的远侧，并且具有一个或多个径向面对的开口。用于治疗狭窄性气道的方法包括将医疗装置插入患者的气道中，并使气道扩张和通气。

76. 发明申请

US20110112512A1 DEVICES AND METHODS FOR TREATING MAXILLARY SINUS DISEASE 有权
标题翻译：用于治疗最大麻疹疾病的装置和方法
公开(公告)号：US20110112512A1
公开(公告)日：2011-05-12
申请号：US12639919
申请日：2009-12-16
申请人： Ketan P. Muni , Hung V. Ha , Randy S. Chan , Daniel T. Harfe , Howard Levine
发明人： Ketan P. Muni , Hung V. Ha , Randy S. Chan , Daniel T. Harfe , Howard Levine
IPC分类号： A61M29/02
CPC分类号： A61B17/24 , A61B17/3415 , A61B17/3417 , A61B17/3421 , A61B17/3478 , A61B2090/062 , A61F11/004 , A61M25/0075 , A61M25/0084 , A61M25/0102 , A61M25/04 , A61M25/0662 , A61M25/10 , A61M27/00 , A61M29/02 , A61M31/00 , A61M2025/0018 , A61M2025/0681 , A61M2025/105 , A61M2025/1054 , A61M2210/0681
摘要： Devices and methods are described for improving drainage and/or aeration of maxillary sinuses and for treating maxillary sinus disease. Spacer devices are implanted through natural or man-made openings in the maxillary sinus. In some embodiments, the spacer device is loaded with a therapeutic substance which then exits the device over a desired time period to treat maxillary sinus disease.
摘要翻译：描述了用于改善上颌窦引流和/或通气并用于治疗上颌窦疾病的装置和方法。通过上颌窦中的天然或人造开口植入间隔器。在一些实施方案中，间隔装置装有治疗物质，然后治疗物质在所需时间段内离开装置以治疗上颌窦疾病。

77. 发明授权

US06569148B2 Methods for emboli containment 失效
公开(公告)号：US06569148B2
公开(公告)日：2003-05-27
申请号：US09769775
申请日：2001-01-25
申请人： Celso J. Bagaoisan , Jefferey C. Bleam , Ketan P. Muni , Gholam RezaZadno Azizi
发明人： Celso J. Bagaoisan , Jefferey C. Bleam , Ketan P. Muni , Gholam RezaZadno Azizi
IPC分类号： A61M3100
CPC分类号： A61M25/10184 , A61B17/22 , A61B2017/22067 , A61B2017/22084 , A61B2217/005 , A61M25/0009 , A61M25/0026 , A61M25/0029 , A61M25/005 , A61M25/0053 , A61M25/0054 , A61M25/0068 , A61M25/007 , A61M25/0075 , A61M25/008 , A61M25/09 , A61M25/09033 , A61M25/10 , A61M25/1011 , A61M25/1018 , A61M25/1027 , A61M25/104 , A61M2025/0018 , A61M2025/0037 , A61M2025/0081 , A61M2025/0183 , A61M2025/09008 , A61M2025/09175 , A61M2025/1015 , A61M2025/1031 , A61M2025/1052 , A61M2025/1079 , A61M2025/109 , A61M2025/1093 , B29C55/04
摘要： A multi-catheter emboli containment system is disclosed which is adapted to provide at least one pair of optimized paths for irrigation and aspiration fluid flow. Through careful design of the cross-sectional area of these paths, the present system is able to be compactly utilized in even the smaller size blood vessels. The catheter system itself is provided with occlusive devices to form an emboli containment chamber in which irrigation and aspiration occur. The catheter system of the present invention provides an improved emboli containment and removal system which can be utilized in a wide range of vessel diameters. The system is easy to use and can quickly and efficiently evacuate the containment chamber.

78. 发明授权

US06454741B1 Aspiration method 有权
标题翻译：吸气法
公开(公告)号：US06454741B1
公开(公告)日：2002-09-24
申请号：US09537471
申请日：2000-03-24
申请人： Ketan P. Muni , Gholam Reza Zadno-Azizi , Celso Bagaoisan
发明人： Ketan P. Muni , Gholam Reza Zadno-Azizi , Celso Bagaoisan
IPC分类号： A61M2900
CPC分类号： A61M25/104 , A61B17/22 , A61B18/245 , A61B2017/22067 , A61B2017/22084 , A61B2017/320716 , A61M2025/09183 , A61M2025/1015 , A61M2025/1052 , A61M2025/109 , A61M2025/1093
摘要： A method for the treatment of a stenosis or an occlusion in a blood vessel in which an occlusive device is first delivered and activated at a site distal to the occlusion to at least partially occlude the vessel. A therapy catheter is then introduced to treat the occlusion and a debris removal device is delivered to aspirate debris from the vessel. The present invention eliminates the need for a separate irrigation catheter and irrigation fluid which allows the procedure to be performed quickly and efficiently, and is especially useful in the removal of occlusion from saphenous vein graft, the coronary and carotid arteries, arteries above the aortic arch and vessels of similar size and pressure.
摘要翻译：一种用于治疗血管狭窄或闭塞的方法，其中闭塞装置首先在远端闭塞位置被输送和活化以至少部分地封闭血管。然后引入治疗导管以治疗闭塞，并且输送碎片去除装置以从血管吸出碎屑。本发明消除了对单独的冲洗导管和冲洗流体的需要，其允许快速且有效地执行该过程，并且特别可用于从隐静脉移植物，冠状动脉和颈动脉，主动脉弓上方的动脉中除去闭塞和类似尺寸和压力的容器。

79. 发明授权

US6126634A Balloon assembly with separately inflatable sections 失效
标题翻译：气球组件与单独充气部分
公开(公告)号：US6126634A
公开(公告)日：2000-10-03
申请号：US763927
申请日：1996-12-12
申请人： Celso Jacinto Bagaoisan , Ketan P. Muni
发明人： Celso Jacinto Bagaoisan , Ketan P. Muni
IPC分类号： A61M25/00 , A61M29/02
CPC分类号： A61M25/1029 , A61M25/104 , A61M2025/1059 , A61M2025/1072
摘要： A dilatation or other similar catheter for intraluminal use which has an elongated shaft and an inflatable member or section on the distal extremity of the catheter shaft which has multiple working sections, a first working section which elastically expands upon inflation to a first pressure within a first pressure range and a second working section which elastically expands upon inflation to a second pressure within a second pressure range which is at least in part higher than the first pressure range. The first working section may be inflated to secure the catheter within the body lumen and then the second working section may be inflated to dilatate the body lumen.
摘要翻译：一种用于管腔内使用的扩张或其它类似的导管，其具有细长轴和在导管轴的远端上的可膨胀构件或部分，其具有多个工作部分，第一工作部分，其在充气时弹性膨胀至第一压力压力范围和第二工作部分，其在充气时弹性膨胀到在至少部分高于第一压力范围的第二压力范围内的第二压力。第一工作部分可以被充气以将导管固定在体腔中，然后第二工作部分可以被充气以使体腔膨胀。

80. 发明授权

US5853408A In-vivo modification of the mechanical properties of surgical devices 失效
标题翻译：手术器械的机械性能的体内修饰
公开(公告)号：US5853408A
公开(公告)日：1998-12-29
申请号：US457325
申请日：1995-06-01
申请人： Ketan P. Muni
发明人： Ketan P. Muni
IPC分类号： A61M25/00 , A61N5/00
CPC分类号： A61M25/0075 , A61M25/008 , A61M2025/0064 , A61M2025/09083
摘要： The mechanical properties of various angioplastic surgical devices are altered in order to enhance their transportability through the vascular system by changing their operating temperature while situated within the body. Temperature increases are utilized to increase flexibility or cause devices to assume certain configurations while a temperature decrease serves to increase stiffness and rupture strength.
摘要翻译：改变各种血管生成手术装置的机械性能，以通过改变其位于体内的操作温度来增强其通过血管系统的运输性能。利用温度升高来增加柔性，或者使装置呈现某种构型，同时降低温度以增加刚度和断裂强度。

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