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    • 71. 发明授权
    • Vacuum assisted biopsy device
    • 真空辅助活检装置
    • US07988642B2
    • 2011-08-02
    • US12039364
    • 2008-02-28
    • Terry D. HardinJoseph L. MarkWilliam O. HodgeZachary R. NicosonMichael E. Miller
    • Terry D. HardinJoseph L. MarkWilliam O. HodgeZachary R. NicosonMichael E. Miller
    • A61B10/02
    • A61B10/0275A61B10/0283A61B2010/0208
    • A biopsy device is disclosed that comprises a cutting element mounted to a handpiece and a vacuum chamber. The cutting element comprises a stylet assembly and an outer cannula assembly. The stylet assembly includes a stylet that includes an open proximal end and a tissue opening at a distal end thereof. The tissue receiving opening is in communication with a lumen extending through the stylet. The outer cannula assembly includes an outer cannula that is slidably mounted over the stylet and has an open distal end with a cutting edge formed thereon. The vacuum chamber is in communication with the lumen of the stylet. The stylet is selectively advanced distally outwardly with respect to outer cannula to expose the tissue opening to targeted tissue. The outer cannula is selectively advanced over the tissue opening to sever tissue, while vacuum is generated in the vacuum chamber and delivered to the tissue opening through the lumen. The vacuum causes tissue to be drawn into and maintained in the tissue opening while the outer cannula severs tissue to obtain a biopsy core.
    • 公开了一种活检装置,其包括安装到手持件和真空室的切割元件。 切割元件包括探针组件和外套管组件。 探针组件包括探针,该探针包括开放的近端和在其远端的组织开口。 组织接收口与延伸穿过通丝针的内腔连通。 外套管组件包括外套管,其可滑动地安装在通球针上方并且具有形成在其上的切削刃的敞开的远端。 真空室与探针的内腔连通。 探针相对于外套管选择性向外远端向外推进,以将组织开口暴露于目标组织。 选择性地将外套管推进到组织开口上以切断组织,同时在真空室中产生真空并通过内腔输送到组织开口。 真空使得组织被拉入并保持在组织开口中,同时外套管切断组织以获得活组织检查核心。
    • 73. 发明授权
    • Flexible tip medical instrument
    • 柔性尖端医疗器械
    • US07841990B2
    • 2010-11-30
    • US11279258
    • 2006-04-11
    • Joseph L. MarkMichael E. Miller
    • Joseph L. MarkMichael E. Miller
    • A61B10/00
    • A61B10/0275A61B2010/0208A61B2010/045
    • A biopsy device includes a flexible distal portion for obtaining a biopsy sample. The device includes a coring cannula defining a coring relief notch adjacent its distal end having a length longer than a diameter of the cannula. A wire is slidably disposable within the lumen of the coring cannula and defines a sampling cavity adjacent its distal end. A wire relief notch is positioned adjacent the sampling cavity that has a length longer than its width. A firing mechanism engaged to the proximal ends of the coring cannula and the wire is operable to move the coring cannula relative to the wire between a first position retracted within the lumen so that the coring cannula covers the sampling cavity and a second position wherein the distal end of the wire is extended away from the coring cannula to trap tissue from the biopsy site in the cavity.
    • 活检装置包括用于获得活检样本的柔性远端部分。 该装置包括一个取芯套管,其定义邻近其远端的取心凹口,其长度大于套管的直径。 线可滑动地一次性在取心套管的内腔内并且在其远端附近限定采样腔。 电线释放槽口位于采样腔的相邻处,其长度大于其宽度。 接合到取心套管和线的近端的击发机构可操作以在缩回到内腔内的第一位置之间相对于线移动取心套管,使得取心套管覆盖取样腔,而第二位置,其中远端 导线的端部从取芯插管延伸以从腔中的活检部位捕获组织。
    • 74. 发明申请
    • ELECTRO-LUMINESCENT DISPLAY WITH ADJUSTABLE WHITE POINT
    • 具有可调白点的电子显微镜显示
    • US20100289727A1
    • 2010-11-18
    • US12464123
    • 2009-05-12
    • Michael E. MillerMichael L. Boroson
    • Michael E. MillerMichael L. Boroson
    • G09G3/30
    • G09G3/2003G09G3/30G09G3/3208G09G2300/0452G09G2320/0666G09G2330/021H01L27/3213H01L27/322H01L51/5265
    • The present invention provides an EL display adapted to receive a three-color input image signal, including three gamut-defining EL emitters for emitting red, green, and blue colored light and two additional EL emitters for emitting at least two additional colors of light, the chromaticity coordinates of the at least two additional colors of light lying inside the gamut and near the Plankian Locus; a structure for providing a display white point; and a controller responsive, to the provided display white point and the input image signal for providing first separate drive signals for the three gamut-defining EL emitters and second separate drive signals for the two additional EL emitters, wherein the respective luminance values corresponding to the second separate drive signals are each a function of the input image signal and the distances between the display white point and the pseudo-blackbody points of the two additional colors.
    • 本发明提供一种适于接收三色输入图像信号的EL显示器,包括用于发射红色,绿色和蓝色光的三个色域限定EL发射器和用于发射至少两种附加颜色的光的两个附加EL发射器, 位于色域内和Plankian轨迹附近的至少两种附加颜色的色度坐标; 用于提供显示白点的结构; 以及响应于所提供的显示白点和输入图像信号的控制器,用于为三个色域限定EL发射器提供第一分离的驱动信号和用于两个附加EL发射器的第二分离驱动信号,其中相应于 第二单独的驱动信号各自是输入图像信号和两个附加颜色的显示白点和伪黑体点之间的距离的函数。
    • 75. 发明授权
    • Multilumen catheter
    • 多元导管
    • US07833157B2
    • 2010-11-16
    • US12121647
    • 2008-05-15
    • Rebecca GottliebRajiv ShahMary M. MorrisVictor GironMichael E. MillerBradley J. Enegren
    • Rebecca GottliebRajiv ShahMary M. MorrisVictor GironMichael E. MillerBradley J. Enegren
    • A61B5/05A61B5/00
    • A61M25/0032A61B5/028A61B5/14532A61B5/1486A61B5/415A61M5/14244A61M5/1723A61M25/0017A61M25/0023A61M2025/0003A61M2025/0046A61M2230/201Y10T29/49826
    • A multilumen catheter having tubings extending into lumens within the catheter. The lumens may be used for blood, drugs or other medicants. The lumens may also be used for sensors. The junction element, external to the patient, connects the tubings to the lumens. The tubings, also external to the patient, connect to infusion members, to which one or more infusion systems may be connected to deliver blood, drugs and other medicants to the patient. A sensor having a sensing element may extend through the sensor lumen and be positioned internal to the patient for physiological parameter sensing. An external portion of the sensor may be connected to associated electronics to provide automatic monitoring of the physiological parameters and automatic delivery and control of the infusants. Also, a central line catheter for delivering fluids directly into a main artery or vein near the heart, which contains a first lumen to deliver a fluid through the central line catheter and a second lumen containing a sensor capable indicating a characteristic level in blood. The first lumen delivers the fluid downstream of the sensor to prevent any interference between the fluid delivery and the sensor readings. In other versions, the central line catheter can have additional lumens for additional purposes. In addition, the central line catheter can further include a flush sleeve to remove debris around the sensor.
    • 一种多管导管,其具有延伸到导管内腔内的管道。 流明可用于血液,药物或其他药物。 流明也可用于传感器。 患者外部的连接元件将管道连接到管腔。 也在患者外部的管连接到输注构件,一个或多个输注系统可以连接到输注构件,以向患者输送血液,药物和其他药剂。 具有感测元件的传感器可以延伸穿过传感器内腔并且位于患者的内部以用于生理参数感测。 传感器的外部部分可以连接到相关联的电子设备,以提供对生理参数的自动监测以及对输入的自动传送和控制。 另外,一种用于将流体直接输送到心脏附近的主动脉或静脉的中心线导管,其包含用于通过中心线导管输送流体的第一内腔和包含能够指示血液中的特征水平的传感器的第二腔。 第一个内腔在传感器的下游传送流体,以防止流体输送和传感器读数之间的任何干扰。 在其他版本中,中心线导管可以具有另外的流明用于其他目的。 此外,中心线导管还可以包括冲洗套筒以去除传感器周围的碎屑。
    • 80. 发明授权
    • Biopsy needle with integrated guide pin
    • 活检针与集成导销
    • US07658718B2
    • 2010-02-09
    • US11958500
    • 2007-12-18
    • Michael E. MillerDan C. Ireland
    • Michael E. MillerDan C. Ireland
    • A61B10/00
    • A61B10/0275A61B17/3403A61B2010/0208A61B2090/034
    • A biopsy needle assembly for use in a biopsy gun includes coaxially slidably engaged outer needle and inner needles. The inner needle defines a cavity adjacent its distal end for receiving a tissue sample. A first hub is attached to the proximal end of the inner needle, and a second hub is attached to the proximal end of the outer needle. An elongated pin having a first end and a second end is fixedly attached to the first hub at the first end of the pin. The second end is in sliding contact with the second hub so that the second hub and the pin are slidable relative to each other. A stop engagement is provided between the second end of the pin and the second hub and is configured to prevent disengagement of the outer and inner needles and to maintain a specific physical relationship between the hubs.
    • 用于活检枪的活检针组件包括同轴可滑动地接合的外针和内针。 内针限定邻近其远端的腔以接收组织样本。 第一轮毂附接到内针的近端,并且第二轮毂连接到外针的近端。 具有第一端和第二端的细长销在销的第一端处固定地附接到第一毂。 第二端部与第二轮毂滑动接触,使得第二轮毂和销可相对于彼此滑动。 在销的第二端和第二轮毂​​之间提供止动接合,并且构造成防止外针和内针的分离并且保持轮毂之间的特定物理关系。