专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

71. 发明申请

US20070167700A1 Method for accurate in vivo delivery of a therapeutic agent to a target area of an organ 审中-公开
标题翻译：将治疗剂精确体内递送至器官的靶区域的方法
公开(公告)号：US20070167700A1
公开(公告)日：2007-07-19
申请号：US11314589
申请日：2005-12-21
申请人： Norbert Rahn , Jan Boese , Martin Kleen
发明人： Norbert Rahn , Jan Boese , Martin Kleen
IPC分类号： A61B5/05
CPC分类号： A61B17/3478 , A61B34/20 , A61B90/36 , A61B2017/00247 , A61B2018/00392 , A61B2034/2051 , A61B2090/374 , A61B2090/376 , A61K35/12 , A61M25/0082 , A61M25/0084 , A61M2025/0091
摘要： In a method for accurately delivering a therapeutic agent to a target area of an organ of a living subject, such as for injecting stem cells into the myocardium of the heart, a 3D image, in which the target area and a delivery path thereto are visible, is obtained prior to delivery of the therapeutic agent. The 3D image is displayed, and a catheter is introduced into the subject and a real time positional indication of the catheter in the subject is obtained and incorporated into the displayed image, providing visual support for guiding the catheter to the target area. When the catheter is at the target area, the therapeutic agent is injected into the target area via the catheter. The distribution of the injected therapeutic agent relative to the target area is then monitored in the displayed image.
摘要翻译：在将用于将干细胞注入心脏心脏的活体受试者的器官的目标区域精确输送的方法中，其中目标区域和其输送路径可见的3D图像在递送治疗剂之前获得。显示3D图像，并且将导管引入到对象中，并且获得被检体内的导管的实时位置指示并将其合并到所显示的图像中，从而提供用于将导管引导到目标区域的视觉支撑。当导管位于目标区域时，经由导管将治疗剂注入目标区域。然后在所显示的图像中监测注射的治疗剂相对于目标区域的分布。

72. 发明申请

US20070004981A1 Interventional instrument with marking element 有权
标题翻译：具有标记元素的介入仪器
公开(公告)号：US20070004981A1
公开(公告)日：2007-01-04
申请号：US11480192
申请日：2006-06-30
申请人： Jan Boese , Norbert Rahn , Bernhard Sandkamp
发明人： Jan Boese , Norbert Rahn , Bernhard Sandkamp
IPC分类号： A61M25/00 , A61M25/098 , A61B6/00 , A61B8/14
CPC分类号： A61M25/0108 , A61M2025/0008 , A61M2025/1079
摘要： To make interventional instruments such as catheters more easily identifiable in X-ray images, the catheters are provided with marking elements which can be recognized in the X-ray image. Examples of marking elements are sphere-shaped and ring-shaped marking elements, the ring-shaped marking elements being able to identify the catheters in the manner of a barcode and so being able to make different catheters distinguishable from one another in the X-ray image.
摘要翻译：为了在X射线图像中更容易识别诸如导管之类的介入仪器，导管设置有可在X射线图像中识别的标记元件。标记元件的示例是球形和环形标记元件，环形标记元件能够以条形码的方式识别导管，并且能够使得在X射线中彼此可区分的不同导管图片。

73. 发明申请

US20060241518A1 Device for recording electrophysiological signals and for displaying the signals or signal information elements which are derived therefrom 失效
公开(公告)号：US20060241518A1
公开(公告)日：2006-10-26
申请号：US11347549
申请日：2006-02-03
申请人： Jan Boese , Martin Kleen , Norbert Rahn
发明人： Jan Boese , Martin Kleen , Norbert Rahn
IPC分类号： A61M25/00
CPC分类号： A61B5/044 , A61B5/0422
摘要： Device for recording electrophysiological signals and for displaying the signals or signal information elements which are derived therefrom, comprising a catheter which includes a plurality of electrodes arranged in a distributed manner for signal recording and a rendition device for displaying the signals or the individual signal information elements which relate to the respective electrodes and are derived from the signals, wherein the signals or the signal information elements can be displayed in a display which is modeled on the geometric arrangement of the electrodes at the catheter or on the geometric arrangement of the electrodes during the signal recording.

74. 发明申请

US20060227136A1 Method for representing preoperatively recorded three-dimensional image data when recording two-dimensional X-ray images 审中-公开
标题翻译：用于在记录二维X射线图像时表示术前记录的三维图像数据的方法
公开(公告)号：US20060227136A1
公开(公告)日：2006-10-12
申请号：US11398883
申请日：2006-04-06
申请人： Jan Boese , Norbert Rahn
发明人： Jan Boese , Norbert Rahn
IPC分类号： G06T17/00
CPC分类号： G06T15/20 , G06T2210/41
摘要： In a method for representing preoperatively recorded three-dimentional image data when recording two-dimentional X-ray images, parameters for recording the two-dimentional X-ray images are placed in relation to two-dimentional representations of the three-dimentional image data and coupled thereto. When paraneters for recording the two-dimentional X-ray images change, corresponding two-dimentional representations of the three-dimentional image data are shown on a screen.
摘要翻译：在记录二维X射线图像时用于表示术前记录的三维图像数据的方法，用于记录二维X射线图像的参数与三维图像数据的二维表示相关，耦合到其上。当用于记录二维X射线图像的偏振片改变时，三维图像数据的对应二维表示显示在屏幕上。

75. 发明申请

US20060208931A1 Method of using configuration files for configuring technical devices 有权
标题翻译：使用配置文件配置技术设备的方法
公开(公告)号：US20060208931A1
公开(公告)日：2006-09-21
申请号：US11375987
申请日：2006-03-15
申请人： Jan Boese , Martin Kleen , Norbert Rahn
发明人： Jan Boese , Martin Kleen , Norbert Rahn
IPC分类号： H03M7/00
CPC分类号： G06Q30/0603 , G06Q10/06 , H04L41/0846 , H04L41/0856 , H04L41/18 , H04L67/104 , H04L67/1063 , H04L67/303 , Y10S707/99937 , Y10S707/99953
摘要： The present invention relates to a method for the provision and use of configuration files containing essential configuration data for configuring technical devices. With the method the configuration data is uploaded by one or more participants in the method via a network onto a server and downloaded by users of the technical devices as configuration files from the server via the network. When a configuration file is downloaded by a user or when a downloaded configuration file is used by a user to configure a technical device, the participant who uploaded the configuration data of the downloaded or used configuration file onto the server receives a reimbursement. The present method simplifies the configuration of units for the users of technical devices and represents an incentive for experienced users to make the configurations they have created themselves also available to other users.
摘要翻译：本发明涉及一种提供和使用包含配置技术设备的基本配置数据的配置文件的方法。使用该方法，配置数据由方法中的一个或多个参与者通过网络上传到服务器上，并且通过技术设备的用户作为配置文件从服务器经由网络下载。当用户下载配置文件或用户使用下载的配置文件配置技术设备时，将下载或使用的配置文件的配置数据上传到服务器上的参与者收到报销。本方法简化了技术设备用户的单元配置，并表示有经验的用户激励自己创建的配置也可供其他用户使用。

76. 发明申请

US20060009754A1 Device for determining the relative position of a plurality of catheters in the human body 失效
标题翻译：用于确定人体中多个导管的相对位置的装置
公开(公告)号：US20060009754A1
公开(公告)日：2006-01-12
申请号：US11165098
申请日：2005-06-23
申请人： Jan Boese , Martin Kleen , Norbert Rahn
发明人： Jan Boese , Martin Kleen , Norbert Rahn
IPC分类号： A61B18/04
CPC分类号： A61B18/1492 , A61B34/20 , A61B2018/00839 , A61B2034/2051
摘要： Device for determining the relative position of two or more catheters in the human body, there being disposed on each catheter (4, 5), preferably in the area of the catheter tip, at least one measuring electrode (ME1-ME8; ME9, ME10) which can be connected to a voltage source together with one or more measuring electrodes of a further catheter, wherein the resistance between the measuring electrodes, and hence the distance of the measuring electrodes, can be determined via a current measurement.
摘要翻译：用于确定人体中两个或更多个导管的相对位置的装置，优选地在导管尖端的区域中设置在每个导管（4,5）上，至少一个测量电极（ME 1 -ME 8; ME 9，ME 10），其可以与另一个导管的一个或多个测量电极连接到电压源，其中测量电极之间的电阻以及测量电极的距离可以通过电流测量来确定。

77. 发明授权

US08538504B2 Method for merging medical images 有权
标题翻译：合并医学图像的方法
公开(公告)号：US08538504B2
公开(公告)日：2013-09-17
申请号：US11007492
申请日：2004-12-08
申请人： Martin Kleen , Marcus Pfister , Norbert Rahn
发明人： Martin Kleen , Marcus Pfister , Norbert Rahn
IPC分类号： A61B5/05
CPC分类号： A61B5/0073 , A61B5/0071 , A61B5/0084 , A61B5/055 , A61B6/032 , A61B6/5247 , A61B8/00 , A61B8/5238 , G06K9/32 , G06K2209/05 , G06T7/38
摘要： A method for the merged display of first image information captured using a first imaging device with second image information captured using a second imaging device is provided. The first imaging device records fluorescence images of the area under examination. A second 3D image data record of the area under examination is recorded using an examination procedure based on electromagnetic radiation, such as computer tomography (CT) or magnetic resonance imaging (MRI). The 3D fluorescence image data record and the second 3D image data record are registered with one another, and one or more fluorescence-optically marked, relevant areas of the examination volume, on the basis of the mapping rules determined by the registration process, are displayed on a monitor.
摘要翻译：提供了一种用于使用第一成像装置捕获的第一图像信息的合并显示的方法，其具有使用第二成像装置捕获的第二图像信息。第一个成像装置记录被检查区域的荧光图像。使用基于诸如计算机断层摄影（CT）或磁共振成像（MRI）的电磁辐射的检查程序记录被检查区域的第二3D图像数据记录。将3D荧光图像数据记录和第二3D图像数据记录彼此登记，并且基于由注册过程确定的映射规则，显示检查卷的一个或多个荧光光学标记的相关区域在监视器上。

78. 发明授权

US07480398B2 Method of registering a sequence of 2D image data with 3D image data 有权
标题翻译：使用3D图像数据注册2D图像数据序列的方法
公开(公告)号：US07480398B2
公开(公告)日：2009-01-20
申请号：US11076536
申请日：2005-03-08
申请人： Martin Kleen , Marcus Pfister , Norbert Rahn
发明人： Martin Kleen , Marcus Pfister , Norbert Rahn
IPC分类号： G06K9/00 , G06K9/36 , A61B5/05
CPC分类号： G06T3/0037 , A61B8/12 , A61B8/483 , A61B8/5238 , G06T7/33 , G06T7/38 , G06T7/66 , G06T2207/30101
摘要： The present invention relates to a method for registration of a sequence of 2D image data (5) of a hollow channel (2), in particular of a vessel, recorded with an imaging endoluminal instrument (1) when the relative displacement positions of the instrument (1) in the hollow channel (2) are known, with 3D image data (8) of the hollow channel (2). In the method a three-dimensional path of a central axis (10) of a definable section of the hollow channel (2) is determined from the 3D image data (8), the three-dimensional path of the central axis (10) is converted into a rectilinear path by a first transformation of the 3D image data (8) of the definable section of the hollow channel (2) and transformation parameters required for the first transformation are stored. A combined 3D image data record (11) is generated from the sequence of 2D image data (5) by a parallel side-by-side arrangement on a central straight line in accordance with the known relative displacement positions, and is first registered with the transformed 3D image data (9) by equating the central straight line with the rectilinear path of the central axis (10) and suitable translation for superposition of a shared reference point. The combined 3D image data record (11) or 2D image data (5) contained therein is then registered with the 3D image data (3), taking into account the stored transformation parameters.
摘要翻译：本发明涉及用于记录仪器的相对位移位置时记录有成像腔内仪器（1）的中空通道（2）的二维图像数据序列（2）的序列的方法，特别是记录有成像腔内仪器（1）的容器（2）中的3D图像数据（8）已知在空心通道（2）中的（1）。在该方法中，根据3D图像数据（8）确定空心通道（2）的可定义部分的中心轴线（10）的三维路径，中心轴线（10）的三维路径为通过中空通道（2）的可定义部分的3D图像数据（8）的第一变换，转换为直线路径，并存储第一变换所需的变换参数。根据已知的相对位移位置，通过平行并排布置在中央直线上从2D图像数据（5）的序列生成组合的3D图像数据记录（11），并且首先与通过将中心直线与中心轴线（10）的直线路径相等，以及用于叠加共享参考点的合适的平移来改变3D图像数据（9）。然后将其中包含的组合3D图像数据记录（11）或2D图像数据（5）与3D图像数据（3）一起注册，同时考虑所存储的变换参数。

79. 发明授权

US08986217B2 Mapping catheter as well as mapping catheter apparatus and associated method 有权
标题翻译：测绘导管以及映射导管装置及相关方法
公开(公告)号：US08986217B2
公开(公告)日：2015-03-24
申请号：US12605547
申请日：2009-10-26
申请人： Jan Boese , Norbert Rahn , Bernhard Sandkamp
发明人： Jan Boese , Norbert Rahn , Bernhard Sandkamp
IPC分类号： A61B5/01 , G01K13/00 , A61B5/042 , A61B5/06 , A61B5/00 , A61B18/14 , A61B18/00
CPC分类号： A61B5/042 , A61B5/01 , A61B5/06 , A61B5/062 , A61B5/721 , A61B18/1492 , A61B2018/00005 , A61B2018/00011 , A61B2018/00041 , A61B2018/00797 , A61B2018/00839
摘要： The invention relates to a mapping catheter for determination of data of an area of an organ embodied as a flat surface, especially of the heart, to be presented graphically, with at least one thermosensor essentially aligned in the direction of the longitudinal axis of the mapping catheter for determination of temperature-related data which is arranged at a tip of the mapping catheter being provided in the distal area of the mapping catheter for introduction into the organ.
摘要翻译：本发明涉及一种用于确定体现为平坦表面（特别是心脏的平面）的器官的区域的数据的映射导管，以图形方式呈现，至少一个热敏传感器在映射的纵向轴线的方向上基本对准用于确定布置在映射导管的尖端处的温度相关数据的导管设置在映射导管的远端区域中以引入器官。

80. 发明授权

US08583214B2 Method for visually supporting an invasive examination or therapy of the heart with the aid of an invasive instrument 有权
标题翻译：借助于侵入性仪器视觉上支持侵入性检查或治疗心脏的方法
公开(公告)号：US08583214B2
公开(公告)日：2013-11-12
申请号：US11524611
申请日：2006-09-21
申请人： Jan Boese , Norbert Rahn
发明人： Jan Boese , Norbert Rahn
IPC分类号： A61B5/055 , A61B8/00
CPC分类号： A61B6/12 , A61B5/7285 , A61B6/541 , A61B8/543 , A61B34/20 , A61B90/36 , A61B2017/00243 , A61B2090/376
摘要： To visually support a catheter ablation in the heart, three-dimensional image data have been used prior to the intervention. During ablation, the position of the catheter is pinpointed by an orientation system. The orientation system acquires electroanatomical 3D mapping data. The two-dimensional image data is assigned to the 3D mapping data in the correct position and dimensions which is a time-consuming step. The invention makes provision for the orientation system being in a fixed location relative to the X-ray system so that a positionally and dimensionally correct alignment of the X-ray image data set with the 3D mapping data is no longer required. An image or surface based 3D-3D alignment of the three-dimensional data acquired prior to the intervention with the three-dimensional X-ray image data is considerably less time-consuming than alignment thereof with the 3D mapping data and is more reliable because more structures is recognized in the three-dimensional X-ray image data.
摘要翻译：为了可视地支持心脏中的导管消融，在干预之前已经使用三维图像数据。在消融期间，导管的位置由定位系统精确定位。取向系统获取电解剖3D绘图数据。将二维图像数据分配给三维映射数据，其中正确的位置和尺寸是耗时的步骤。本发明提供了相对于X射线系统的定位系统在固定位置的设置，使得不再需要X射线图像数据集与3D映射数据的位置和尺寸校正对准。在三维X射线图像数据的干预之前获取的三维数据的图像或基于表面的3D-3D对准与3D映射数据的对准相比，耗时更少，并且更可靠，因为更多在三维X射线图像数据中识别结构。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式