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    • 74. 发明授权
    • Photoresponsive liposome
    • 光响应脂质体
    • US5169635A
    • 1992-12-08
    • US873678
    • 1992-04-24
    • Mitsunori OnoYoshihisa Tsukada
    • Mitsunori OnoYoshihisa Tsukada
    • A61K9/127C07D309/10C07F9/09C07F9/10C07H13/06
    • C07H13/06A61K9/1271A61K9/1272C07D309/10C07F9/091C07F9/094C07F9/10Y10S436/829Y10T428/2982
    • A photoresponsive liposome which comprises a compound represented by the following general formula (I): ##STR1## wherein R.sub.1 is an alkyl group; R.sub.2, R.sub.3, R.sub.4 and R.sub.5, which may be the same or different, are selected from the group consisting of an alkyl group, a substituted alkyl group, an alkoxy group, a substituted alkoxy group, a halogen atom and a hydrogen atom; R.sub.6 and R.sub.7, which may be the same or different, are an alkyl group or a hydrogen atom; n is an integer of 1 to 2; and X represents a hydrophilic group, a hydrophobic group or a combination of hydrophilic and hydrophobic groups, bonded through a connecting group, provided that any of these hydrophilic and hydrophobic groups has such properties that the compound represented by the general formula (I) becomes available as a component forming the membrane of liposome.
    • 一种光响应性脂质体,其包含由以下通式(I)表示的化合物:其中R 1为烷基; R2,R3,R4和R5可以相同或不同,选自烷基,取代的烷基,烷氧基,取代的烷氧基,卤素原子和氢原子; R6和R7可以相同或不同,是烷基或氢原子; n为1〜2的整数, 并且X表示通过连接基团键合的亲水基团,疏水基团或亲水基团和疏水基团的组合,条件是这些亲水基团和疏水基团中的任何一个具有使通式(I)表示的化合物变得可用的性质 作为形成脂质体膜的成分。