专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

71. 发明申请

US20080044498A1 Therapeutic or prophylactic agent, and method of treating or preventing a disease 审中-公开
标题翻译：治疗或预防剂，以及治疗或预防疾病的方法
公开(公告)号：US20080044498A1
公开(公告)日：2008-02-21
申请号：US11905945
申请日：2007-10-05
申请人： Tatsuji Enoki , Kinuko Ogawa , Hiromu Ohnogi , Katsumi Sugiyama , Nobuko Muraki , Hiroaki Sagawa , Ikunoshin Kato
发明人： Tatsuji Enoki , Kinuko Ogawa , Hiromu Ohnogi , Katsumi Sugiyama , Nobuko Muraki , Hiroaki Sagawa , Ikunoshin Kato
IPC分类号： A61K36/232
CPC分类号： A61K36/232 , A23L2/52 , A23L33/105 , A23V2002/00 , A23V2200/328 , A23V2250/21
摘要： The present invention relates to a therapeutic agent or prophylactic agent for a disease accompanying an abnormality in an amount of insulin or insulin response, an insulin-mimetic action agent, a food, beverage, or feed for treating or preventing a disease accompanying an abnormality in an amount of insulin or insulin response, an agent for enhancement of glucose uptake into a cell, and an agent for induction of an adipocyte differentiation, each comprising as an effective ingredient a processed product derived from a plant belonging to Umbelliferae.
摘要翻译：本发明涉及一种伴随胰岛素或胰岛素反应量异常的疾病的治疗剂或预防剂，用于治疗或预防伴随异常的疾病的胰岛素模拟作用剂，食品，饮料或饲料一定量的胰岛素或胰岛素反应，用于增强葡萄糖摄入细胞的药剂和用于诱导脂肪细胞分化的药剂，其各自包含衍生自属于伞形属植物的植物的加工产品作为有效成分。

72. 发明申请

US20070112066A1 Remedy 失效
标题翻译：补救
公开(公告)号：US20070112066A1
公开(公告)日：2007-05-17
申请号：US10581034
申请日：2004-12-01
申请人： Hiromu Ohnogi , Katsumi Sugiyama , Tatsuji Enoki , Eiji Kobayashi , Hiroaki Sagawa , Ikunoshin Kato
发明人： Hiromu Ohnogi , Katsumi Sugiyama , Tatsuji Enoki , Eiji Kobayashi , Hiroaki Sagawa , Ikunoshin Kato
IPC分类号： A61K31/343 , A61K31/12 , C07C49/794
CPC分类号： C07D493/08 , A23K20/121 , A23L33/10 , C07C49/835 , C07C49/84 , C07C409/08 , C07D307/80
摘要： The present invention provides a novel chalcone compound, its derivative or a salt thereof, each having a suppressive action of NO production or an inhibitory action of aldose reductase. In addition, the present invention provides a medicament, a food, a beverage or a feed having a therapeutic or prophylactic effect for a disease showing sensitivity to the compound, by utilizing the physiological actions of the compound.
摘要翻译：本发明提供了具有NO产生抑制作用或醛糖还原酶抑制作用的新型查耳酮化合物及其衍生物或其盐。此外，本发明通过利用化合物的生理作用，提供对化合物显示敏感性的疾病具有治疗或预防作用的药物，食品，饮料或饲料。

73. 发明申请

US20060160219A1 Method of transferring mutation into target nucleic acid 审中-公开
标题翻译：将突变转移到靶核酸的方法
公开(公告)号：US20060160219A1
公开(公告)日：2006-07-20
申请号：US10520008
申请日：2003-07-11
申请人： Chunyu Cao , Hiroaki Sagawa , Ikunoshin Kato
发明人： Chunyu Cao , Hiroaki Sagawa , Ikunoshin Kato
IPC分类号： C12N15/63
CPC分类号： C07K14/43595 , C12N15/102
摘要： A method of transferring a mutation into the base sequence of a target nucleic acid characterized by comprising the step of preparing a DNA having a reversed repetitive sequence wherein the base sequence of the DNA having the reversed repetitive sequence is homologous with the target nucleic acid and has a base sequence containing the mutation to be transferred into the target nucleic acid, and the step of transferring the DNA having the reversed repetitive sequence into cells; and a kit for the method.
摘要翻译：将突变转移到靶核酸的碱基序列中的方法，其特征在于包括制备具有反向重复序列的DNA的步骤，其中具有反向重复序列的DNA的碱基序列与靶核酸同源且具有含有要转移到靶核酸中的突变的碱基序列和将具有反向重复序列的DNA转移到细胞中的步骤; 和一个方法的工具包。

74. 发明授权

US07056671B2 Isothermal chimeric primer nucleic acid amplification methods using blocking oglionucleotide 失效
标题翻译：等温嵌合引物核酸扩增方法使用阻断寡核苷酸
公开(公告)号：US07056671B2
公开(公告)日：2006-06-06
申请号：US10486645
申请日：2002-08-20
申请人： Tatsuji Enoki , Hiroaki Sagawa , Ikunoshin Kato
发明人： Tatsuji Enoki , Hiroaki Sagawa , Ikunoshin Kato
IPC分类号： C12Q1/68 , C12P19/34
CPC分类号： C12Q1/6844 , C12Q1/6853 , C12Q2600/156 , C12Q2525/186 , C12Q2521/301 , C12Q2531/119 , C12Q2525/117 , C12Q2525/113
摘要： Methods of amplifying a target nucleic acid whereby the target nucleic acid is amplified in the presence of a deoxyribonucleotide triphosphate, a DNA polymerase having strand displacement activity, at least one chimeric oligonucleotide primer, at least one upstream block oligonucleotide and a RNase H; wherein the chimeric oligonucleotide primer contains a ribonucleotide positioned at the 3′-terminus; wherein the upstream block oligonucleotide is capable of annealing to a region 3′ to a portion in the nucleic acid as the template to which the chimeric oligonucleotide primer anneals; and compositions and kits thereof.
摘要翻译：在脱氧核糖核苷酸三磷酸，具有链置换活性的DNA聚合酶，至少一种嵌合寡核苷酸引物，至少一个上游嵌段寡核苷酸和RNase H的存在下扩增靶核酸的扩增靶核酸的方法; 其中所述嵌合寡核苷酸引物含有位于3'末端的核糖核苷酸; 其中所述上游嵌段寡核苷酸能够退火至所述核酸的部分区域3'作为所述嵌合寡核苷酸引物退火的模板; 及其组合物和试剂盒。

75. 发明申请

US20060051316A1 Remedy 审中-公开
标题翻译：补救
公开(公告)号：US20060051316A1
公开(公告)日：2006-03-09
申请号：US10537333
申请日：2003-12-05
申请人： Hiromu Ohnogi , Katsumi Sugiyama , Hiroaki Sagawa , Ikunoshin Kato
发明人： Hiromu Ohnogi , Katsumi Sugiyama , Hiroaki Sagawa , Ikunoshin Kato
IPC分类号： A61K31/74 , A61K31/737 , A61K31/727 , A61K31/715
CPC分类号： A61K36/02 , A23L33/10 , A61K31/216 , A61K31/737 , A61K31/78
摘要： The present invention relates to a therapeutic agent or prophylactic agent for a disease requiring enhancement of bone morphogenetic protein production or promotion of osteogenesis; an agent for enhancement of bone morphogenetic protein production or an agent for promotion of osteogenesis, a food, beverage or feed for enhancement of bone mornhogenetic protein production or promotion of osteogenesis, characterized in that each comprises as an effective ingredient at least one compound selected from the group consisting of (a) an acidic saccharide, (b) a polyacrylic acid, (c) chlorogenic acid and (d) an oxidation processed product of chlorogenic acid, or an extract derived from algae.
摘要翻译：本发明涉及需要增强骨形态发生蛋白产生或促进成骨的疾病的治疗剂或预防剂; 用于增强骨形态发生蛋白质产生的药物或用于促进成骨的药剂，用于增强骨发生蛋白质产生或促进成骨的食品，饮料或饲料，其特征在于，每种药物包含作为有效成分的至少一种选自由（a）酸性糖，（b）聚丙烯酸，（c）绿原酸和（d）绿原酸的氧化加工产物或源自藻类的提取物组成的组。

76. 发明申请

US20060034949A1 Remedy 审中-公开
标题翻译：补救
公开(公告)号：US20060034949A1
公开(公告)日：2006-02-16
申请号：US10524015
申请日：2003-08-06
申请人： Tatsuji Enoki , Kinuko Ogawa , Hiromu Ohnogi , Katsumi Sugiyama , Nobuko Muraki , Hiroaki Sagawa , Ikunoshin Kato
发明人： Tatsuji Enoki , Kinuko Ogawa , Hiromu Ohnogi , Katsumi Sugiyama , Nobuko Muraki , Hiroaki Sagawa , Ikunoshin Kato
IPC分类号： A61K36/232
CPC分类号： A61K36/232 , A23L2/52 , A23L33/105 , A23V2002/00 , A23V2200/328 , A23V2250/21
摘要： The present invention relates to a therapeutic agent or prophylactic agent for a disease accompanying an abnormality in an amount of insulin or insulin response, an insulin-mimetic action agent, a food, beverage, or feed for treating or preventing a disease accompanying an abnormality in an amount of insulin or insulin response, an agent for enhancement of glucose uptake into a cell, and an agent for induction of an adipocyte differentiation, each comprising as an effective ingredient a processed product derived from a plant belonging to Umbelliferae.
摘要翻译：本发明涉及一种伴随胰岛素或胰岛素反应量异常的疾病的治疗剂或预防剂，用于治疗或预防伴随异常的疾病的胰岛素模拟作用剂，食品，饮料或饲料一定量的胰岛素或胰岛素反应，用于增强葡萄糖摄入细胞的药剂和用于诱导脂肪细胞分化的药剂，其各自包含衍生自属于伞形属植物的植物的加工产品作为有效成分。

77. 发明授权

US06518317B1 Antiviral agents 失效
标题翻译：抗病毒剂
公开(公告)号：US06518317B1
公开(公告)日：2003-02-11
申请号：US09367185
申请日：1999-08-09
申请人： Hiroaki Sagawa , Nobuto Koyama , Hideto Chono , Kazutoh Takesako , Ikunoshin Kato
发明人： Hiroaki Sagawa , Nobuto Koyama , Hideto Chono , Kazutoh Takesako , Ikunoshin Kato
IPC分类号： A61K31122
CPC分类号： C07C323/58 , A23K20/105 , A23L2/52 , A23L33/10 , A61K31/122 , C07C323/59 , Y10S514/894
摘要： An antiviral agent which is characterized in containing at least one compound selected from a group consisting of 4,5-dihydroxy-2-cyclopenten-1-one represented by the following formula [I] and an optically active substance and a salt thereof as an effective component.
摘要翻译：一种抗病毒剂，其特征在于含有至少一种选自由下式[I]表示的4,5-二羟基-2-环戊烯-1-酮的化合物和光学活性物质及其盐作为有效成分。

78. 发明授权

US06380262B1 5-membered ring compounds 失效
标题翻译： 5元环化合物
公开(公告)号：US06380262B1
公开(公告)日：2002-04-30
申请号：US09762265
申请日：2001-02-06
申请人： Eiji Kobayashi , Hiromu Ohnogi , Nobuto Koyama , Katsushige Ikai , Hiroaki Sagawa , Ikunoshin Kato
发明人： Eiji Kobayashi , Hiromu Ohnogi , Nobuto Koyama , Katsushige Ikai , Hiroaki Sagawa , Ikunoshin Kato
IPC分类号： A61K3112
CPC分类号： C07K5/0215 , A61K38/00
摘要： 5-Membered ring compounds represented by general formula (I), optically active isomers thereof or salts of the same. These compounds have physiological activities including a carcinostatic effect. In said formula the bond shown by the dotted line in the 5-membered ring represents that this 5-membered ring may be either a cyclopentene ring having a double bond or a saturated cyclopentane ring, and when the 5-membered ring is a cyclopentene ring, X is OR1, Y is ═O and Z is H, and when it is a cyclopentane ring, X is ═O, Y is OR2 and Z is OR3, (wherein R1 is R4 or —(CO)—R5; R2 is H, —R6 or —(CO)—R7; and R3 is H, R8 or (CO)—R9 (wherein R4, R5, R6, R7, R8 and R9 are the same or different and each represents an aliphatic, aromatic or aliphatic aromatic group, and R5, R7 and R9 may be each H), provided that the case where R2═R3═H is excluded); and W represents a residue obtained by eliminating SH from an SH-containing compound.
摘要翻译：由通式（I）表示的5-元环化合物，其旋光异构体或其盐。这些化合物具有包括致癌作用的生理活性。在所述式中，五元环中虚线所示的键表示该5元环可以是具有双键或饱和环戊烷环的环戊烯环，当5元环为环戊烯环时 X为OR 1，Y为= O且Z为H，当为环戊烷环时，X为= O，Y为OR 2，Z为OR 3，（其中R1为R4或 - （CO）-R5; R2为 H，-R6或 - （CO）-R7; R3为H，R8或（CO）-R9（其中R4，R5，R6，R7，R8和R9相同或不同，各自表示脂族，芳族或脂族芳族基团，R 5，R 7和R 9可以各自为H），条件是排除R2 = R3 = H的情况）; W表示通过从含SH化合物中除去SH而得到的残基。

79. 发明申请

US20100068192A1 Method for Production of T Cell Population 审中-公开
标题翻译： T细胞群体生产方法
公开(公告)号：US20100068192A1
公开(公告)日：2010-03-18
申请号：US11992661
申请日：2006-09-27
申请人： Tatsuji Enoki , Akiko Kato , Mitsuko Ideno , Hiroaki Sagawa , Ikunoshin Kato
发明人： Tatsuji Enoki , Akiko Kato , Mitsuko Ideno , Hiroaki Sagawa , Ikunoshin Kato
IPC分类号： A61K35/12 , C12N5/00 , C12N5/02
CPC分类号： C12N5/0636 , A61K35/17 , A61K38/19 , A61K39/00 , A61K39/0011 , A61K2039/5158 , C12N15/86 , C12N2501/515 , C12N2501/58 , C12N2740/10043 , A61K2300/00
摘要： A method for preparing a T cell population, wherein the T cell population expresses CD45RA and expresses at least one selected from the group consisting of CD62L, CCR7, CD27, and CD28, characterized in that the method comprises the step of culturing a cell population comprising a T cell, in the presence of fibronectin, a fragment thereof or a mixture thereof.
摘要翻译：一种制备T细胞群体的方法，其中所述T细胞群表达CD45RA并表达选自CD62L，CCR7，CD27和CD28的至少一种，其特征在于所述方法包括培养细胞群的步骤，所述细胞群包含在纤连蛋白存在下，其T细胞，其片段或其混合物。

80. 发明申请

US20080227204A1 PROCESS FOR PRODUCING CYTOTOXIC LYMPHOCYTE 审中-公开
标题翻译：生产细胞淋巴细胞的方法
公开(公告)号：US20080227204A1
公开(公告)日：2008-09-18
申请号：US11831423
申请日：2007-07-31
申请人： Hiroaki Sagawa , Mitsuko Ideno , Ikunoshin Kato
发明人： Hiroaki Sagawa , Mitsuko Ideno , Ikunoshin Kato
IPC分类号： C12N5/02
CPC分类号： C12N5/0638 , A61K2035/124 , C12N5/0636 , C12N2501/58 , C12N2510/00
摘要： The present invention relates to a method for preparing a cytotoxic lymphocyte characterized in that the method comprises the step of carrying out at least one of induction, maintenance and expansion of a cytotoxic lymphocyte in the presence of fibronectin, a fragment thereof or a mixture thereof.
摘要翻译：本发明涉及一种制备细胞毒性淋巴细胞的方法，其特征在于该方法包括在纤连蛋白，其片段或其混合物存在下，进行细胞毒性淋巴细胞的诱导，维持和扩增中的至少一种的步骤。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式