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71. 发明授权

US06787777B1 Nuclear imaging system and method using segmented field of view 失效
标题翻译：核成像系统和方法采用分段视野
公开(公告)号：US06787777B1
公开(公告)日：2004-09-07
申请号：US09710395
申请日：2000-11-09
申请人： Daniel Gagnon , Chi-Hua Tung
发明人： Daniel Gagnon , Chi-Hua Tung
IPC分类号： G01T1166
CPC分类号： G01T1/1615
摘要： A gamma camera includes a plurality of detectors (32, 34) for detecting emission radiation emitted from within a subject and transmission radiation which has traversed a subject to be imaged, the subject attenuating the radiation. Each detector generates position and energy data. At least one transmission radiation source (54, 54′) transmits transmission radiation through an examination region (36) to a first segment (74, 74′) of the opposite detector. In one embodiment, segment selector circuitry (88) connected with the detectors selectively disables a portion of each detector head during collection of emission data, transmission data, or both. In another embodiment, transmission radiation is received by the first segment (74, 74′) simultaneously with emission radiation being received by a second segment (72, 72′) of each detector. The first segment is uncollimated or collimated for the transmission radiation source. In SPECT imaging, the second segment carries a collimator for defining trajectories of received emission radiation. A first electronic storage medium (90) connected with the segment selector circuitry stores transmission data and a second electronic storage medium (86) connected with the segment selector circuitry stores emission data. A first reconstruction processor (92) connected with the first electronic storage medium generates a transmission image representation (94). A second reconstruction processor (100, 101) connected with the second electronic storage medium generates an emission image representation (102, 103).
摘要翻译：伽马照相机包括用于检测从被摄体内发射的发射辐射的多个检测器（32,34）和穿过要被成像的被摄体的透射辐射，所述受试者衰减辐射。每个检测器产生位置和能量数据。至少一个透射辐射源（54,54'）将透射辐射通过检查区域（36）传输到相对检测器的第一段（74,74'）。在一个实施例中，与检测器连接的段选择器电路（88）在收集发射数据，传输数据或两者期间选择性地禁用每个检测器头的一部分。在另一个实施例中，由发射辐射同时由第一段（74,74'）接收传输辐射，由发射辐射由每个检测器的第二段（72,72'）接收。传输辐射源的第一段未被准直或准直。在SPECT成像中，第二段携带准直器来定义接收到的发射辐射的轨迹。与段选择器电路连接的第一电子存储介质（90）存储传输数据，并且与段选择器电路连接的第二电子存储介质（86）存储发射数据。与第一电子存储介质连接的第一重建处理器（92）产生传输图像表示（94）。与第二电子存储介质连接的第二重建处理器（100,101）产生发射图像表示（102,103）。

72. 发明授权

US06628983B1 Nuclear imaging systems and methods with feature-enhanced transmission imaging 失效
标题翻译：核成像系统和具有特征增强传输成像的方法
公开(公告)号：US06628983B1
公开(公告)日：2003-09-30
申请号：US09696153
申请日：2000-10-25
申请人： Daniel Gagnon
发明人： Daniel Gagnon
IPC分类号： A61B600
CPC分类号： G01T1/1648 , A61B6/037
摘要： A transmission radiation source (30a) radiates at a plurality of energy levels within a specified energy range. The energy range is divided into two or more energy subranges. Detectors (20a-20c) detect the position or trajectory and energy of transmitted radiation and emitted radiation. A sorter (48) sorts the detected radiation into the appropriate energy subrange. Data for each subrange is stored in a plurality of transmission data memories (50a-50n). Reconstruction processors (52a-52n) generate a transmission image representation (54a-54n) representative of each energy subrange. A combine processor (60) weights each energy subrange image representation with an assigned weighting factor (64a-64n) to provide enhancement of at least one feature when the images are combined to generate weighted image representations (72, 74, 76). The plurality of transmission images are also combined with equal weighting to generate an image representation (70) used to generate attenuation correction factors (80) for correcting the emission data (46). A reconstruction processor (84) generates a corrected emission image representation (86). The emission image can be combined with one of the feature-enhanced structural images (72, 74, 76) using a combiner (92) and displayed, allowing the functional emission image to be located with respect to structural or anatomical features. Also, a feature-enhanced structural image (72, 74, 76), can advantageously be used to register the emission image (86) with an image (100) from another modality, such as a computed tomography (CT) image.
摘要翻译：透射辐射源（30a）以规定的能量范围内的多个能级辐射。能量范围分为两个或更多个能量子范围。检测器（20a-20c）检测发射辐射和发射辐射的位置或轨迹和能量。分拣机（48）将检测到的辐射分类到适当的能量子范围内。每个子范围的数据被存储在多个发送数据存储器（50a-50n）中。重构处理器（52a-52n）生成代表每个能量子范围的传输图像表示（54a-54n）。组合处理器（60）用分配的加权因子（64a-64n）对每个能量子范围图像表示进行加权，以在组合图像以产生加权图像表示（72,74,76）时提供至少一个特征的增强。多个传输图像也被相等加权组合以产生用于产生用于校正发射数据（46）的衰减校正系数（80）的图像表示（70）。重建处理器（84）产生校正的发射图像表示（86）。发射图像可以使用组合器（92）与特征增强的结构图像（72,74,76）中的一个组合并被显示，从而允许功能发射图像相对于结构或解剖特征定位。此外，特征增强结构图像（72,74,76）可以有利地用于使用来自另一模态（例如计算机断层摄影（CT））图像的图像（100）来登记发射图像（86）。

73. 发明授权

US06552349B2 Detector with non-circular field of view 失效
公开(公告)号：US06552349B2
公开(公告)日：2003-04-22
申请号：US10041198
申请日：2002-01-08
申请人： Daniel Gagnon , Christopher G. Matthews
发明人： Daniel Gagnon , Christopher G. Matthews
IPC分类号： G01T120
CPC分类号： G01T1/1648
摘要： A radiation detector includes a slit collimator. A radiation detector receives radiation which has been received in each of the slits. The aspect ratio of the detector is approximately three, and each semiconductor radiation detector has a transverse dimension which is less than that of its respective slit. A reconstruction processor generates an image indicative of the radiation received by the detectors. The detector may be rotated about a fixed axis. Alternately, the detector may be translated in coordination with its rotation to provide a substantially square field of view.

74. 发明授权

US06175116B1 Hybrid collimation and coincidence imager for simultaneous positron and single photon imaging 失效
标题翻译：用于同时正电子和单光子成像的混合准直和重合成像器
公开(公告)号：US06175116B1
公开(公告)日：2001-01-16
申请号：US09065743
申请日：1998-04-24
申请人： Daniel Gagnon , Frank P. DiFilippo
发明人： Daniel Gagnon , Frank P. DiFilippo
IPC分类号： G01T1164
CPC分类号： G01T1/1603 , A61B6/037 , G01T1/2985
摘要： A gamma camera includes detector heads disposed about an examination region. A high energy collimator collimates the radiation received by each of the detector heads. Either a positron emitting radionuclide or a positron emitting radionuclide and a single photon emitting radionuclide is introduced into an object to be imaged. Radiation which is received by the detectors within a coincidence time interval and radiation which is received by either of the detectors but having an energy characteristic of a positron annihilation are used to generate coincidence data. Radiation which is not indicative of coincidence radiation but which has an energy characteristic of the single photon emitting radionuclide is used to generate single photon data. The data is processed and used to generate one or more images of the object.
摘要翻译：伽马照相机包括围绕检查区域设置的检测器头。高能准直器准直由每个检测器头接收的辐射。将发射放射性核素的正电子或发射放射性核素的正电子和发射放射性核素的单个光子引入待成像的对象中。在一致时间间隔内由检测器接收的辐射和由任一检测器接收但具有正电子湮灭的能量特性的辐射被用于产生符合数据。使用不表示符合辐射但具有单光子发射放射性核素的能量特性的辐射用于产生单光子数据。数据被处理并用于生成对象的一个或多个图像。

75. 发明授权

US6147353A Image shift for gamma camera 失效
标题翻译：伽马相机的图像移位
公开(公告)号：US6147353A
公开(公告)日：2000-11-14
申请号：US86947
申请日：1998-05-29
申请人： Daniel Gagnon , Christopher G. Matthews , Frank P. DiFilippo
发明人： Daniel Gagnon , Christopher G. Matthews , Frank P. DiFilippo
IPC分类号： G01T1/164 , G01T1/166
CPC分类号： G01T1/1648 , G01T1/166
摘要： A gamma camera includes first and second detectors which face an examination region. The detectors are rotatable about the examination region and translatable in a direction tangential to the examination region. Translation of the detectors is coordinated with the rotation of the detectors about the examination so as to increase the effective field of view of the detectors. In a first embodiment, the detectors are translated in the transverse direction when the detectors are located at each of a plurality of positions about the examination region. In a second embodiment, translation of the detectors is coordinated such that, for a given projection angle, the first detector is used to detect radiation data from a subset of the region of interest.
摘要翻译：伽马照相机包括面向检查区域的第一和第二检测器。检测器可围绕检查区域旋转并且可在与检查区域相切的方向上平移。检测器的翻转与检测器围绕检查的旋转协调，以增加检测器的有效视场。在第一实施例中，当检测器位于围绕检查区域的多个位置中的每一个位置时，检测器在横向平移。在第二实施例中，协调检测器的平移，使得对于给定的投影角度，第一检测器用于检测来自感兴趣区域的子集的辐射数据。

76. 发明授权

US09494667B2 Hybrid MR/PET with correction for radiation absorption by MR coil 有权
标题翻译：混合MR / PET与MR线圈的辐射吸收校正
公开(公告)号：US09494667B2
公开(公告)日：2016-11-15
申请号：US12598484
申请日：2008-04-17
申请人： Michael A. Morich , Gordon D. Demeester , Daniel Gagnon
发明人： Michael A. Morich , Gordon D. Demeester , Daniel Gagnon
IPC分类号： G01R33/381 , G01R33/48 , G01T1/16 , G01T1/164
CPC分类号： G01R33/481 , G01R33/4808 , G01T1/1603 , G01T1/1647
摘要： An imaging method comprises: acquiring magnetic resonance data of a subject using a magnetic resonance component (30, 30′) disposed with the subject; acquiring nuclear imaging data of the subject with the magnetic resonance component disposed with the subject; determining a position of the magnetic resonance component respective to a frame of reference of the nuclear imaging data; and reconstructing the nuclear imaging data (60) to generate a nuclear image (62) of at least a portion of the subject. The reconstructing includes adjusting at least one of the nuclear imaging data and the nuclear image based on a density map (46) of the magnetic resonance component and the determined position of the magnetic resonance component respective to the frame of reference of the nuclear imaging data to correct the nuclear image for radiation absorption by the magnetic resonance component.
摘要翻译：一种成像方法包括：使用与受检者一起设置的磁共振成分（30,30'）来获取对象的磁共振数据; 用设置在对象的磁共振成分获取对象的核成像数据; 确定所述磁共振成分相对于所述核成像数据的参考系的位置; 以及重构所述核成像数据（60）以产生所述受试者的至少一部分的核图像（62）。重建包括基于磁共振分量的密度图（46）和与核成像数据的参考系的相应的磁共振分量的确定的位置来调整核成像数据和核图像中的至少一个，通过磁共振成分校正核图像的辐射吸收。

77. 发明授权

US09101273B2 Apparatus, detector, and method for applying a pixel by pixel bias on demand in energy discriminating computed tomography (CT) imaging 有权
标题翻译：用于在能量识别计算机断层摄影（CT）成像中按要求应用逐像素偏差的装置，检测器和方法
公开(公告)号：US09101273B2
公开(公告)日：2015-08-11
申请号：US13531141
申请日：2012-06-22
申请人： Daniel Gagnon , Xiaolan Wang
发明人： Daniel Gagnon , Xiaolan Wang
IPC分类号： H05G1/56 , G01T1/24 , A61B6/03 , A61B6/00 , G01T1/29 , G01N23/04
CPC分类号： A61B6/032 , A61B6/4233 , A61B6/4241 , A61B6/54 , A61B6/545 , G01N23/04 , G01N2223/423 , G01N2223/507 , G01T1/24 , G01T1/2985 , H05G1/56
摘要： A Computed Tomography (CT) method, apparatus, and detector, which includes a plurality of energy-discriminating detector elements configured to capture incident X-ray photons emitted from an X-ray source. Each of the plurality of energy-discriminating detector elements of the detector is configured to have a respective bias voltage individually switched ON or OFF, based on a signal received from a controller.
摘要翻译：一种计算机断层扫描（CT）方法，装置和检测器，其包括被配置为捕获从X射线源发射的入射X射线光子的多个能量鉴别检测器元件。检测器的多个能量鉴别检测器元件中的每一个被配置为基于从控制器接收到的信号，使各自的偏置电压单独地接通或断开。

78. 发明授权

US08750587B2 Method and system for PET image reconstruction using portion of event data 有权
标题翻译：使用事件数据部分进行PET图像重建的方法和系统
公开(公告)号：US08750587B2
公开(公告)日：2014-06-10
申请号：US12091752
申请日：2006-10-30
申请人： Daniel Gagnon , Jeffrey A. Kolthammer
发明人： Daniel Gagnon , Jeffrey A. Kolthammer
IPC分类号： A61B6/03
CPC分类号： A61B6/037 , G06T11/006
摘要： A method and system for use in positron emission tomography, wherein a list-based reconstructor means (129) is configured to generate first portion volumetric data responsive to a first portion of a plurality of positron annihilation events detected during a positron emission tomography scan; generate a human-readable image indicative of the first portion volumetric data; use a list-based reconstruction technique to generate composite volumetric data responsive to the first portion volumetric data and a second portion of the plurality of positron annihilation events; and generate a composite human-readable image indicative of the composite volumetric data. In another aspect the reconstructor (129) is configured to selecting first or second portion event quantities responsive to one or more parameters including image definition requirements and processing time requirements.
摘要翻译：一种用于正电子发射断层摄影的方法和系统，其中基于列表的重建器装置（129）被配置为响应于在正电子发射断层摄影扫描期间检测到的多个正电子湮灭事件的第一部分而产生第一部分体积数据; 生成指示第一部分体积数据的人类可读图像; 使用基于列表的重建技术来响应于第一部分体积数据和多个正电子湮灭事件的第二部分来生成复合体积数据; 并生成指示复合体积数据的复合人类可读图像。在另一方面，重建器（129）被配置为响应于包括图像定义要求和处理时间要求的一个或多个参数来选择第一或第二部分事件量。

79. 发明授权

US08466419B2 System and method for enhanced sampling via helical scanning and list-mode reconstruction in positron emission tomography 有权
标题翻译：用于通过正电子发射断层扫描中的螺旋扫描和列表模式重建来增强采样的系统和方法
公开(公告)号：US08466419B2
公开(公告)日：2013-06-18
申请号：US12571524
申请日：2009-10-01
申请人： Daniel Gagnon
发明人： Daniel Gagnon
IPC分类号： G01T1/164
CPC分类号： G01T1/2985
摘要： A positron emission tomography (PET) scanner system, including a detector that acquires PET event information, the detector being configured to move during acquisition of the PET event information; a first motion unit that acquires first event information of a position of a patient bed, the patient bed being configured to move during acquisition of the PET event information; a second motion unit that acquires second event information of the detector; an event collector that generates an event list of events that includes the PET event information, the first event information, and the second event information; and a list-mode reconstructing unit that reconstructs an image by processing the generated event list.
摘要翻译：一种正电子发射断层摄影（PET）扫描仪系统，包括获取PET事件信息的检测器，所述检测器被配置为在获取PET事件信息期间移动; 第一运动单元，其获取患者床的位置的第一事件信息，所述患者床被配置为在获取所述PET事件信息期间移动; 第二运动单元，其获取所述检测器的第二事件信息; 事件收集器，其生成包括PET事件信息，第一事件信息和第二事件信息的事件的事件列表; 以及通过处理所生成的事件列表来重构图像的列表模式重建单元。

80. 发明授权

US08440976B2 Method for optimizing step size in a multi-step whole-body PET imaging 有权
标题翻译：用于在多步全身PET成像中优化步长的方法
公开(公告)号：US08440976B2
公开(公告)日：2013-05-14
申请号：US13010237
申请日：2011-01-20
申请人： Daniel Gagnon
发明人： Daniel Gagnon
IPC分类号： G01T1/166
CPC分类号： G01T1/2985 , A61B6/037
摘要： A method of imaging a region of interest (ROI) in an object, the ROI having an axial extent greater than an axial FOV of a PET scanner. The method includes determining a number of overlapping scans of the PET scanner necessary to image at least the axial extent of the ROI, wherein each scan has a same axial length equal to the axial FOV, and each scan overlaps an adjacent scan by a predetermined overlap percentage of the axial length of each scan. The method includes determining a total amount of excess scanning length of the scans based on the number, the axial extent of the ROI, and the axial FOV, and determining a new overlap percentage so that a new total amount of excess scanning length is zero.
摘要翻译：一种对物体中的感兴趣区域（ROI）进行成像的方法，所述ROI的轴向范围大于PET扫描器的轴向FOV。该方法包括确定至少对ROI的轴向范围进行成像所必需的PET扫描器的重叠扫描的数量，其中每个扫描具有等于轴向FOV的相同轴向长度，并且每个扫描与相邻扫描重叠预定重叠每次扫描的轴向长度的百分比。该方法包括基于数量，ROI的轴向范围和轴向FOV来确定扫描的多余扫描长度的总量，并且确定新的重叠百分比，使得新的总量超过扫描长度为零。

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