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71. 发明申请

US20120172624A1 PROCESS FOR PREPARING DECANECARBOXYLIC ACIDS 有权
标题翻译：制备癸酰氧基酸的方法
公开(公告)号：US20120172624A1
公开(公告)日：2012-07-05
申请号：US13386523
申请日：2010-05-25
申请人： Michael Grass , Alfred Kaizik , Hans-Gerd Lueken , Wilfried Bueschken
发明人： Michael Grass , Alfred Kaizik , Hans-Gerd Lueken , Wilfried Bueschken
IPC分类号： C07C51/373
CPC分类号： C07C45/74 , C07C45/50 , C07C45/62 , C07C51/235 , C07C47/02 , C07C47/21 , C07C53/128
摘要： The invention relates to a process for preparing a mixture of isomeric decane-carboxylic acids, which comprises the following steps:a) hydroformylation of a hydrocarbon mixture containing linear C4-olefins using a rhodium-containing catalyst system;b) aldol condensation of a mixture of aliphatic C5-aldehydes obtained from step a);c) selective hydrogenation of the mixture of unsaturated C10-aldehydes from step b) to aliphatic C10-aldehydes;d) uncatalysed oxidation of the mixture of aliphatic C10-aldehydes from step c) to give a mixture having a proportion of at least 70% by mass of 2-propylheptanoic acid, based on the total content of isomeric decanecarboxylic acids.
摘要翻译：本发明涉及一种制备异构癸烷 - 羧酸的混合物的方法，其包括以下步骤：a）使用含铑催化剂体系加氢甲酰化含有线性C 4 - 烯烃的烃混合物; b）从步骤a）获得的脂族C 5 - 醛的混合物的醛醇缩合; c）选自氢化来自步骤b）的不饱和C10-醛的混合物至脂族C 10 - 醛; d）来自步骤c）的脂族C 10 - 醛混合物的未催化氧化，得到基于异构癸烷羧酸的总含量的至少70质量％的2-丙基庚酸的混合物。

72. 发明授权

US08202959B2 Process for preparing polymers from 3-methylbut-1-ene 有权
公开(公告)号：US08202959B2
公开(公告)日：2012-06-19
申请号：US13095541
申请日：2011-04-27
申请人： Michael Grass , Franz Nierlich , Walter Kaminsky , Stefanie Derlin , Klaus-Diether Wiese , Dagmara Ortmann
发明人： Michael Grass , Franz Nierlich , Walter Kaminsky , Stefanie Derlin , Klaus-Diether Wiese , Dagmara Ortmann
IPC分类号： C08F4/642 , C08F4/6592 , C08F210/14
CPC分类号： C08F210/16 , C08F4/65912 , C08F4/6592 , C08F10/00 , C08F210/06 , Y10S526/943 , C08F4/65927 , C08F210/14 , C08F2500/03 , C08F2500/20
摘要： The present invention relates to a copolymer which contains 3-methylbut-1-ene as a comonomer and which contains ethene or propene as a further monomer, the proportion of the incorporated 3-methylbut-1-ene being 0.1 to 40 mol %, and to a process for preparing such copolymers, the polymerization being performed in the presence of a catalyst which comprises at least one cyclopentadienyl group.

73. 发明申请

US20120136190A1 PRODUCTION OF 3-METHYLBUT-1-EN BY MEANS OF DEHYDRATION OF 3-METHYLBUTANE-1-OL 审中-公开
标题翻译：通过3-甲基丁-1-醇脱水制备3-甲基-1-
公开(公告)号：US20120136190A1
公开(公告)日：2012-05-31
申请号：US13322527
申请日：2010-04-28
申请人： Alfred Kaizik , Thomas Quandt , Michael Grass , Markus Winterberg , Wilfried Bueschken
发明人： Alfred Kaizik , Thomas Quandt , Michael Grass , Markus Winterberg , Wilfried Bueschken
IPC分类号： C07C1/20
CPC分类号： C07C1/24 , C07C11/10
摘要： The invention relates to a process for preparing 3-methyl-1-butene by dehydration of 3-methyl-1-butanol over an aluminium-containing oxide in the temperature range from 200 to 450° C. in the gas phase or mixed liquid/gas phase, characterized in that an aluminium-containing oxide having a predominantly mesoporous pore structure whose:a) relative proportion of macropores is less than 15%;b) distribution of the pore diameter has a monomodal maximum in the range of mesopores from 3.6 to 50 nm;c) average pore diameter of all pores is in the range of mesopores and macropores from 5 to 20 nm;d) composition comprises more than 80% of gamma-aluminium oxide, is used.
摘要翻译：本发明涉及通过在气相或混合液体/液体中在200-450℃的含铝氧化物上脱水3-甲基-1-丁醇来制备3-甲基-1-丁烯的方法，气相，其特征在于具有主要介孔孔结构的含铝氧化物：a）大孔相对比例小于15％; b）孔径分布在介孔范围为3.6〜50nm的单峰最大值; c）所有孔的平均孔径在5〜20nm的介孔和大孔的范围内; d）组合物包含大于80％的γ-氧化铝。

74. 发明申请

US20120114213A1 MULTI-MODALITY BREAST IMAGING 有权
标题翻译：多模态乳腺成像
公开(公告)号：US20120114213A1
公开(公告)日：2012-05-10
申请号：US13384265
申请日：2010-07-12
申请人： Thomas Buelow , Michael Grass , Klaus Erhard
发明人： Thomas Buelow , Michael Grass , Klaus Erhard
IPC分类号： G06K9/00
CPC分类号： G06T7/0032 , G06T7/344 , G06T2207/10088 , G06T2207/10116 , G06T2207/30068
摘要： A system for multi-modality breast imaging comprises a first shape model constructing sub-system (1) for constructing a first shape model of the breast as represented in a first image (9), in which the breast has its natural shape, a second shape model constructing sub-system (2) for constructing a second shape model of the breast as represented in a second image (10), in which the breast is compressed by using a compression paddle, and a deformation estimating sub-system (3) for estimating a volumetric deformation field (12) defining a mapping between the first image (9) and the second image (10) on the basis of the shape models and an elastic deformation model (11) of the breast, the deformation estimating sub-system (3) being arranged to estimate the volumetric deformation field (12) on the basis of a first tissue surface of the breast in the first image (9) and a second tissue surface of the breast in the second image (10).
摘要翻译：一种用于多模式乳房成像的系统，包括构成子系统（1）的第一形状模型，用于构建乳房的第一形状模型，如第一图像（9）所示，其中乳房具有其自然形状，第二形状模型用于构造乳房的第二形状模型的形状模型构造子系统（2），如第二图像（10）所示，其中通过使用压缩桨来压缩乳房，以及变形估计子系统（3）用于基于形状模型和乳房的弹性变形模型（11）来估计限定第一图像（9）和第二图像（10）之间的映射的体积变形场（12），变形估计子步骤系统（3）被布置为基于第一图像（9）中的乳房的第一组织表面和第二图像（10）中的乳房的第二组织表面来估计体积变形场（12）。

75. 发明申请

US20120057671A1 DATA ACQUISITION AND VISUALIZATION MODE FOR LOW DOSE INTERVENTION GUIDANCE IN COMPUTED TOMOGRAPHY 审中-公开
标题翻译：计算机图像中低剂量干预指导的数据采集和可视化模式
公开(公告)号：US20120057671A1
公开(公告)日：2012-03-08
申请号：US13320941
申请日：2010-05-05
申请人： Michael Grass , Eberhard Sabastian Hansis
发明人： Michael Grass , Eberhard Sabastian Hansis
IPC分类号： G01N23/04
CPC分类号： A61B6/032 , A61B6/027 , A61B6/12 , A61B6/4441 , A61B6/466 , A61B6/542 , A61B2034/102 , A61B2034/2065 , A61B2090/3762
摘要： A system and method for monitoring a guided intervention device includes determining (306) a position of an intervention device inside a subject using a radiation source to image the intervention device. A circular acquisition is performed (304) to update the position of the intervention device wherein the acquisition includes skipping view angles by turning off a radiation source at given angular positions. A model of the intervention device is generated (308) to provide a virtual image of the intervention device against a background of the subject. Movement of the intervention device is modeled (310) during the skipped view angles to provide substantially real-time tracking of the intervention device.
摘要翻译：用于监测引导干预装置的系统和方法包括使用辐射源确定（306）干预装置在受试者内的位置以对干预装置成像。执行循环采集（304）以更新干预装置的位置，其中采集包括通过在给定的角位置处关闭辐射源来跳过视角。产生干预装置的模型（308）以针对对象的背景提供干预装置的虚拟图像。干预装置的移动在跳过的视角期间被建模（310），以提供对干预装置的基本实时跟踪。

76. 发明申请

US20110243412A1 CORONARY ARTERY SELECTIVE CALCIUM ASSIGNMENT USING LOW DOSE CALCIUM SCORING SCANS 审中-公开
标题翻译：冠状动脉选择性钙分配使用低剂量钙分析扫描
公开(公告)号：US20110243412A1
公开(公告)日：2011-10-06
申请号：US12599044
申请日：2008-05-05
申请人： Michael Grass , Jens Von Berg
发明人： Michael Grass , Jens Von Berg
IPC分类号： G06K9/00
CPC分类号： A61B6/504 , A61B6/481 , A61B6/503
摘要： It is described a method for coronary artery selective calcium assignment by computed tomography, wherein the method comprising the steps of performing a low x-ray dose cardiac calcium scoring scan, obtaining a data set of said cardiac calcium scoring scan, generating reconstructed images from the data set of said cardiac calcium scoring scan, analyzing the reconstructed images for segmented calcium deposits, deriving a data set of calcification from the analysis, wherein a cardiac model is adapted to the reconstructed image such that segmented calcium deposits can be assigned to specific areas of the heart. Further a device (100) for performing a method for coronary artery selective calcium assignment by computed tomography according to the inventive method is described, wherein the device (100) comprises a CT unit (10) for performing a low x-ray dose cardiac calcium scoring scan; an acquisition unit (20) for obtaining a data set of said cardiac calcium scoring scan; a generation unit (30) for generating reconstructed images from the data set of said cardiac calcium scoring scan; an analyzing unit (40) for analyzing the reconstructed images for segmented calcium deposits; a deriving unit (50) for deriving a data set of calcification from the analysis.
摘要翻译：描述了通过计算机断层摄影术进行冠状动脉选择性钙分配的方法，其中所述方法包括以下步骤：执行低X射线剂量心脏钙评分扫描，获得所述心脏钙评分扫描的数据集，从所述心脏钙评分扫描的数据集，分析分割钙沉积物的重建图像，从分析导出钙化数据集，其中心脏模型适应于重建图像，使得分割的钙沉积物可以分配给心脏此外，描述了根据本发明的方法通过计算机断层摄影执行冠状动脉选择性钙分配方法的装置（100），其中所述装置（100）包括用于执行低x射线剂量心脏钙的CT单元（10）得分扫描; 获取单元（20），用于获取所述心脏钙评分扫描的数据集; 用于从所述心脏钙评分扫描的数据集中产生重建图像的生成单元（30）; 分析单元（40），用于分析用于分割的钙沉积物的重建图像; 用于从分析中导出钙化数据集的导出单元（50）。

77. 发明授权

US08022244B2 Method for producing benzoic acid esters 有权
标题翻译：苯甲酸酯的制备方法
公开(公告)号：US08022244B2
公开(公告)日：2011-09-20
申请号：US12140316
申请日：2008-06-17
申请人： Michael Grass , Dietmar Gubisch , Michael Woelk-Faehrmann
发明人： Michael Grass , Dietmar Gubisch , Michael Woelk-Faehrmann
IPC分类号： C07C69/78
CPC分类号： C08K5/101 , C07C67/08 , C07C67/48 , C08L27/06 , C07C69/78
摘要： A process for preparing benzoic esters whose alkoxy groups have from 7 to 13 carbon atoms by reacting benzoic acid with at least one alcohol having from 7 to 13 carbon atoms, the water of reaction formed being removed during the esterification reaction by distillation, and the alcohol not converted in the esterification reaction being removed after the esterification reaction, in which the reaction takes place in the presence of a tin(II) compound as catalyst and, without treatment with a base, the catalyst and/or its derivatives is/are separated off by filtering or by centrifuging from the reaction mixture which remains after the unconverted alcohol has been separated off.
摘要翻译：通过使苯甲酸与至少一种具有7至13个碳原子的醇反应制备烷氧基具有7至13个碳原子的苯甲酸酯的方法，在酯化反应期间通过蒸馏除去形成的反应水，和醇在酯化反应后不转化的酯化反应被转化，其中反应在锡（II）化合物作为催化剂的存在下进行，并且不用碱处理，催化剂和/或其衍生物被分离通过过滤或通过从未转化的醇已经分离后残留的反应混合物离心而离心。

78. 发明授权

US07856079B2 Reconstruction method for computer tomography and computer tomograph 有权
标题翻译：计算机断层扫描和计算机断层扫描重建方法
公开(公告)号：US07856079B2
公开(公告)日：2010-12-21
申请号：US11719304
申请日：2005-11-07
申请人： Tim Nielsen , Michael Grass
发明人： Tim Nielsen , Michael Grass
IPC分类号： A61B6/00
CPC分类号： G06T11/006 , A61B6/027 , G06T2211/424
摘要： It is an object of the invention to provide spiral computer tomography which has a high image quality. It relates to a reconstruction method for computer tomography of the heart, wherein the image is reconstructed from a data component of recordings of a partial detector path of a detector device and from a data component of recordings of a full detector path of the detector device, and to a computer tomograph having a beam source, a drive arrangement for driving the beam source in a spiral path around an object, a detector device for recording the radiation from the beam source which passes at least partially through the object, and a control device for reconstructing data components of a partial detector path and a full detector path.
摘要翻译：本发明的目的是提供具有高图像质量的螺旋计算机断层摄影。本发明涉及用于心脏计算机断层摄影的重建方法，其中根据检测器装置的部分检测器路径的记录的数据分量和检测器装置的完整检测器路径的记录的数据分量来重建图像，以及具有光束源的计算机断层摄影机，用于以围绕物体的螺旋路径驱动光束源的驱动装置，用于记录来自至少部分穿过物体的光束源的辐射的检测器装置，以及控制装置用于重构部分检测器路径和完整检测器路径的数据分量。

79. 发明申请

US20100266182A1 APPARATUS FOR DETERMINING A PARAMETER OF A MOVING OBJECT 审中-公开
标题翻译：用于确定移动对象参数的装置
公开(公告)号：US20100266182A1
公开(公告)日：2010-10-21
申请号：US12741397
申请日：2008-11-04
申请人： Michael Grass , Andy Ziegler
发明人： Michael Grass , Andy Ziegler
IPC分类号： G06K9/00
CPC分类号： G06T7/251 , G06T7/246 , G06T2207/10076 , G06T2207/10081 , G06T2207/20004 , G06T2207/20092 , G06T2207/30048
摘要： The present invention relates to an apparatus for determining a parameter of a moving object, wherein the apparatus comprises an adaptive model providing unit (12) for providing an adaptive model of the object. The user can define the region of the adaptive model by a user interface (13). The apparatus further comprises an image data set providing unit (14) for providing a spatially and temporally dependent image data set of the moving object and an adaptation unit (15) for adapting at least a defined region of the adaptive model to the spatially and temporally dependent image data set for determining a spatially and temporally dependence of the defined region. The parameter of the moving object is determined depending on the spatially and temporally dependence of the defined region by a parameter determining unit (16).
摘要翻译：本发明涉及一种用于确定移动物体的参数的装置，其中，所述装置包括用于提供对象的自适应模型的自适应模型提供单元（12）。用户可以通过用户界面（13）来定义自适应模型的区域。该装置还包括用于提供移动物体的空间和时间上依赖的图像数据集的图像数据集提供单元（14），以及适配单元（15），用于至少将自适应模型的定义区域适应于空间和时间上用于确定所定义区域的空间和时间依赖性的依赖图像数据集。取决于由参数确定单元（16）定义的区域的空间和时间依赖性来确定移动对象的参数。

80. 发明授权

US07813549B2 Image segmentation in a volume data set 有权
标题翻译：卷数据集中的图像分割
公开(公告)号：US07813549B2
公开(公告)日：2010-10-12
申请号：US10596148
申请日：2004-11-26
申请人： Thomas Buelow , Michael Grass , Christian Lorenz , Robert Manzke
发明人： Thomas Buelow , Michael Grass , Christian Lorenz , Robert Manzke
IPC分类号： G06K9/34 , G06K9/00
CPC分类号： G06T7/11 , G06T2207/10081 , G06T2207/30101
摘要： Coronary artery segmentation is a crucial task in cardiac CT image processing. This is often a tedious task performed manually by an operator. According to the present invention, a method is provided which combines data from multiple cardiac phases during the segmentation process in order to deliver a complete and continuous coronary vessel tree. Advantageously, this may allow for an improved visualization and segmentation of vessels, for example, in coronary CTA.
摘要翻译：冠状动脉分割是心脏CT图像处理中的关键任务。这通常是由操作员手动执行的繁琐的任务。根据本发明，提供了一种在分割过程中组合来自多个心脏相的数据以递送完整且连续的冠状动脉血管树的方法。有利地，这可以允许例如在冠状动脉CTA中改善血管的可视化和分割。

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