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71. 发明授权

US09687648B2 Systems and methods for positioning an intraneural electrode array in an auditory nerve 有权
公开(公告)号：US09687648B2
公开(公告)日：2017-06-27
申请号：US15022559
申请日：2013-09-17
申请人： ADVANCED BIONICS AG
发明人： Abhijit Kulkarni , Leonid M. Litvak , Mark B. Downing
IPC分类号： A61N1/00 , A61N1/05 , A61B5/00 , A61B5/0484 , A61B5/053 , A61B5/12 , A61B5/06
CPC分类号： A61N1/0541 , A61B5/04845 , A61B5/0538 , A61B5/061 , A61B5/068 , A61B5/12 , A61B5/4851 , A61B5/686 , A61B5/6877
摘要： An exemplary system may include an intracochlear electrode array configured to be inserted into a cochlea of a patient, an intraneural probe comprising an intraneural electrode contact and configured to be inserted into an auditory nerve of the patient, and a computing system. The computing system may be configured to identify an optimal insertion path for an intraneural electrode array into the auditory nerve of the patient by 1) repeatedly stimulating the intraneural electrode contact of the intraneural probe while the intraneural probe is advanced into the auditory nerve along a probe insertion path, 2) using the intracochlear electrode array to record a plurality of evoked responses that occur in response to the repeated stimulation of the intraneural electrode contact, and 3) determining, based on the plurality of evoked responses, whether the probe insertion path is the optimal insertion path for the intraneural electrode array.

72. 发明授权

US09549265B2 Methods and systems for enhancing pitch associated with an audio signal presented to a cochlear implant patient 有权
标题翻译：用于增强与呈现给人工耳蜗患者的音频信号相关联的音调的方法和系统
公开(公告)号：US09549265B2
公开(公告)日：2017-01-17
申请号：US15079036
申请日：2016-03-23
申请人： ADVANCED BIONICS AG
发明人： Adam B. Strauss , Leonid M. Litvak
IPC分类号： H04R25/00 , G10L25/93
CPC分类号： H04R25/353 , A61N1/36032 , A61N1/36036 , G10L21/0364 , G10L25/93 , H04R25/356 , H04R25/50 , H04R25/505 , H04R25/606 , H04R2225/43 , H04R2225/67 , H04R2430/03 , H04R2460/01
摘要： An exemplary sound processor 1) identifies at least one frequency bin, included in a plurality of frequency bins included in a frequency spectrum of an audio signal that is presented to a cochlear implant patient, that contains spectral energy above a modified spectral envelope, 2) identifies each frequency bin that contains spectral energy below the modified spectral envelope, 3) enhances the spectral energy contained in the at least one frequency bin identified as containing spectral energy above the modified spectral envelope, and 4) compresses the spectral energy contained in each frequency bin identified as containing spectral energy below the modified spectral envelope.
摘要翻译：示例性声音处理器1）识别包括在被呈现给耳蜗植入物患者的音频信号的频谱中的多个频率仓中的包含在修改的频谱包络之上的频谱能量的至少一个频率仓，2）识别包含在修改的频谱包络之下的频谱能量的每个频率仓，3）增强被识别为包含在修改的频谱包络上的频谱能量的至少一个频率仓中的频谱能量，以及4）压缩每个频率中包含的频谱能量 bin被识别为包含在修改的光谱包络之下的光谱能量。

73. 发明申请

US20160331967A1 METHODS AND SYSTEMS FOR FITTING AN ELECTRO-ACOUSTIC STIMULATION SYSTEM TO A PATIENT 有权
标题翻译：用于将电声刺激系统配给患者的方法和系统
公开(公告)号：US20160331967A1
公开(公告)日：2016-11-17
申请号：US15222935
申请日：2016-07-28
申请人： ADVANCED BIONICS AG
发明人： Smita S. Agrawal , Leonid M. Litvak
IPC分类号： A61N1/36 , H04R25/00 , A61N1/372 , A61B5/12 , A61N1/05 , A61B5/04
CPC分类号： A61N1/36036 , A61B5/04001 , A61B5/121 , A61N1/0541 , A61N1/37247 , H04R1/1008 , H04R25/00 , H04R25/505 , H04R25/554 , H04R25/606 , H04R25/70 , H04R2225/67 , H04R2460/03
摘要： An exemplary system includes 1) a stimulation management facility configured to direct an electro-acoustic stimulation (“EAS”) system to concurrently apply acoustic stimulation to a patient by way of a loudspeaker and electrical stimulation to the patient by way of an electrode, and 2) a fitting facility communicatively coupled to the stimulation management facility and configured to detect an interaction between the acoustic stimulation and the electrical stimulation, and set one or more control parameters governing an operation of the EAS system based on the detected interaction. Corresponding systems and methods are also disclosed.
摘要翻译：示例性系统包括：1）刺激管理设备，其配置为引导电声刺激（“EAS”）系统，以通过扬声器同时向患者施加声刺激，并通过电极对患者进行电刺激，以及 2）适合设备，其通信地耦合到刺激管理设施并且被配置为检测声学刺激和电刺激之间的相互作用，并且基于检测到的相互作用设置控制EAS系统的操作的一个或多个控制参数。还公开了相应的系统和方法。

74. 发明授权

US09440072B2 Methods and systems for fitting an electro-acoustic stimulation system to a patient 有权
标题翻译：将电声刺激系统装配到患者的方法和系统
公开(公告)号：US09440072B2
公开(公告)日：2016-09-13
申请号：US14386330
申请日：2013-03-22
申请人： ADVANCED BIONICS AG
发明人： Smita S. Agrawal , Leonid M. Litvak
IPC分类号： A61N1/36 , A61B5/04 , A61B5/12 , A61N1/05 , H04R25/00 , A61N1/372 , H04R1/10
CPC分类号： A61N1/36036 , A61B5/04001 , A61B5/121 , A61N1/0541 , A61N1/37247 , H04R1/1008 , H04R25/00 , H04R25/505 , H04R25/554 , H04R25/606 , H04R25/70 , H04R2225/67 , H04R2460/03
摘要： An exemplary system includes 1) a stimulation management facility configured to direct an electro-acoustic stimulation (“EAS”) system to concurrently apply acoustic stimulation to a patient by way of a loudspeaker and electrical stimulation to the patient by way of an electrode located within a cochlea of the patient during a fitting session, and 2) a fitting facility communicatively coupled to the stimulation management facility and configured to detect, during the fitting session, an interaction between the acoustic stimulation and the electrical stimulation, and set, during the fitting session, one or more control parameters governing an operation of the EAS system based on the detected interaction. Corresponding systems and methods are also disclosed.
摘要翻译：示例性系统包括：1）刺激管理设备，其配置为引导电声刺激（“EAS”）系统，以通过扬声器向患者施加声学刺激，并通过位于内部的电极对患者进行电刺激在装配期间患者的耳蜗，以及2）通信地耦合到刺激管理设施并且被配置为在装配会话期间检测声刺激和电刺激之间的相互作用并且在配合期间设置的拟合设备会话，一个或多个基于检测到的交互来控制EAS系统的操作的控制参数。还公开了相应的系统和方法。

75. 发明授权

US09324339B2 Methods and systems for enhancing pitch associated with an audio signal presented to a cochlear implant patient 有权
标题翻译：用于增强与呈现给人工耳蜗患者的音频信号相关联的音调的方法和系统
公开(公告)号：US09324339B2
公开(公告)日：2016-04-26
申请号：US14375321
申请日：2013-01-25
申请人： ADVANCED BIONICS AG
发明人： Adam B. Strauss , Leonid M. Litvak
IPC分类号： G10L21/00 , G10L21/0364 , A61N1/36 , H04R25/00
CPC分类号： H04R25/353 , A61N1/36032 , A61N1/36036 , G10L21/0364 , G10L25/93 , H04R25/356 , H04R25/50 , H04R25/505 , H04R25/606 , H04R2225/43 , H04R2225/67 , H04R2430/03 , H04R2460/01
摘要： An exemplary method of enhancing pitch of an audio signal presented to a cochlear implant patient includes 1) determining a frequency spectrum of an audio signal presented to a cochlear implant patient, the frequency spectrum comprising a plurality of frequency bins that each contain spectral energy, 2) generating a modified spectral envelope of the frequency spectrum of the audio signal, 3) identifying each frequency bin included in the plurality of frequency bins that contains spectral energy above the modified spectral envelope and each frequency bin included in the plurality of frequency bins that contains spectral energy below the modified spectral envelope, 4) enhancing the spectral energy contained in each frequency bin identified as containing spectral energy above the modified spectral envelope, and 5) compressing the spectral energy contained in each frequency bin identified as containing spectral energy below the modified spectral envelope. Corresponding methods and systems are also disclosed.
摘要翻译：提供给耳蜗植入患者的音频信号的音高的示例性方法包括：1）确定呈现给人工耳蜗患者的音频信号的频谱，所述频谱包括多个频谱箱，每个频率包含频谱能量，2 ）产生所述音频信号的频谱的经修改的频谱包络; 3）识别包含在所述多个频率仓中的每个频率仓，所述多个频率仓包含在所述修改的频谱包络之上的频谱能量，并且所述频率包含在所述多个频率仓中，光谱能量低于修改的光谱包络，4）增强被识别为包含在修改的光谱包络上的光谱能量的每个频率仓中的光谱能量，以及5）压缩被包含在包含被修改的光谱能量以下的光谱能量的每个频率块中的光谱能量频谱包络。还公开了相应的方法和系统。

76. 发明授权

US09288585B2 Spectral contrast enhancement in a cochlear implant speech processor 有权
公开(公告)号：US09288585B2
公开(公告)日：2016-03-15
申请号：US14696080
申请日：2015-04-24
申请人： Advanced Bionics AG
发明人： Abhijit Kulkarni , Leonid M. Litvak , Aniket Saoji
IPC分类号： A61N1/36 , H04R25/00 , G10L19/02
CPC分类号： H04R25/00 , A61N1/36032 , A61N1/36036 , G10L19/0212 , H04R2225/025 , H04R2225/67
摘要： Among other things, enhancing spectral contrast for a cochlear implant listener includes detecting a time domain signal. A first transformation is applied to the detected time domain signal to convert the time domain signal to a frequency domain signal. A second transformation is applied to the frequency domain signal to express the frequency domain signal as a sum of two or more components. A sensitivity of the cochlear implant listener to detect modulation of each component is obtained.

77. 发明授权

US09254384B2 Inner hair cell stimulation model for use by a cochlear implant system 有权
公开(公告)号：US09254384B2
公开(公告)日：2016-02-09
申请号：US14085925
申请日：2013-11-21
申请人： Advanced Bionics AG
发明人： Gene Y. Fridman , Leonid M. Litvak
IPC分类号： A61N1/36
CPC分类号： A61N1/36032 , A61N1/36036
摘要： The stimulation provided in the electrically stimulated cochlea is modulated in accordance with the amplitude of a received acoustic signal and the onset of a sound in a received acoustic signal to provide increased sound perception. An onset time that corresponds to the onset of a sound is detected in an acoustic signal associated with a frequency band. A forcing voltage and a transmitting factor are determined, wherein the forcing voltage and the transmitting factor are associated with the frequency band at the detected onset time. The acoustic signal is modulated as a function of the forcing voltage and the transmitting factor to generate an output signal. The generated output signal can be used to stimulate the cochlea. The modulation strategy can be used in conjunction with sound processing strategies that employ frequency modulation, amplitude modulation, or a combination of frequency and amplitude modulation.

78. 发明授权

US09056205B2 Compensation current optimization for auditory prosthesis systems 有权
标题翻译：用于听觉假体系统的补偿电流优化
公开(公告)号：US09056205B2
公开(公告)日：2015-06-16
申请号：US14286810
申请日：2014-05-23
申请人： Advanced Bionics AG
发明人： Leonid M. Litvak , Myles McLaughlin , Abhijit Kulkarni , Aniket Saoji
IPC分类号： A61N1/00 , A61N1/36 , A61N1/05
CPC分类号： A61N1/36032 , A61N1/0541 , A61N1/36036
摘要： An exemplary system includes an implantable cochlear stimulator implanted within a patient, a short electrode array coupled to the implantable cochlear stimulator and having a plurality of electrodes disposed thereon, and a sound processor communicatively coupled to the implantable cochlear stimulator. The sound processor may direct the implantable cochlear stimulator to apply a main current to a first electrode included in the plurality of electrodes and associated with a first pitch, direct the implantable cochlear stimulator to concurrently apply, during the application of the main current, a compensation current to a second electrode included in the plurality of electrodes and associated with a second pitch, and optimize an amount of the compensation current to result in a target pitch being presented to the patient that is distanced from the first pitch in a pitch direction opposite a pitch direction of the second pitch in relation to the first pitch.
摘要翻译：示例性系统包括植入患者体内的植入式耳蜗刺激器，耦合到可植入耳蜗刺激器并且具有布置在其上的多个电极的短电极阵列以及通信地耦合到可植入耳蜗刺激器的声音处理器。声音处理器可以引导可植入的耳蜗刺激器将主电流施加到包括在多个电极中并与第一音调相关联的第一电极，指示可植入的耳蜗刺激器在施加主电流期间同时施加补偿电流到包括在多个电极中并与第二间距相关联的第二电极，并且优化补偿电流的量以导致目标音调呈现给与第一音调远离第一音调的目标音调，该音调方向与相对于第一间距的第二间距的俯仰方向。

79. 发明申请

US20150057998A1 METHODS AND SYSTEMS FOR ENHANCING PITCH ASSOCIATED WITH AN AUDIO SIGNAL PRESENTED TO A COCHLEAR IMPLANT PATIENT 有权
标题翻译：用于增强与提供给COCHLEAR植入物患者的音频信号相关的PITCH的方法和系统
公开(公告)号：US20150057998A1
公开(公告)日：2015-02-26
申请号：US14375321
申请日：2013-01-25
申请人： ADVANCED BIONICS AG
发明人： Adam B. Strauss , Leonid M. Litvak
IPC分类号： G10L21/0364 , H04R25/00
CPC分类号： H04R25/353 , A61N1/36032 , A61N1/36036 , G10L21/0364 , G10L25/93 , H04R25/356 , H04R25/50 , H04R25/505 , H04R25/606 , H04R2225/43 , H04R2225/67 , H04R2430/03 , H04R2460/01
摘要： An exemplary method of enhancing pitch of an audio signal presented to a cochlear implant patient includes 1) determining a frequency spectrum of an audio signal presented to a cochlear implant patient, the frequency spectrum comprising a plurality of frequency bins that each contain spectral energy, 2) generating a modified spectral envelope of the frequency spectrum of the audio signal, 3) identifying each frequency bin included in the plurality of frequency bins that contains spectral energy above the modified spectral envelope and each frequency bin included in the plurality of frequency bins that contains spectral energy below the modified spectral envelope, 4) enhancing the spectral energy contained in each frequency bin identified as containing spectral energy above the modified spectral envelope, and 5) compressing the spectral energy contained in each frequency bin identified as containing spectral energy below the modified spectral envelope. Corresponding methods and systems are also disclosed.
摘要翻译：提供给耳蜗植入患者的音频信号的音高的示例性方法包括：1）确定呈现给人工耳蜗患者的音频信号的频谱，所述频谱包括多个频谱箱，每个频率包含频谱能量，2 ）产生所述音频信号的频谱的经修改的频谱包络; 3）识别包含在所述多个频率仓中的每个频率仓，所述多个频率仓包含在所述修改的频谱包络之上的频谱能量，并且所述频率包含在所述多个频率仓中，光谱能量低于修改的光谱包络，4）增强被识别为包含在修改的光谱包络上的光谱能量的每个频率仓中的光谱能量，以及5）压缩被包含在包含被修改的光谱能量以下的光谱能量的每个频率块中的光谱能量频谱包络。还公开了相应的方法和系统。

80. 发明申请

US20150049890A1 METHODS AND SYSTEMS FOR FITTING AN ELECTRO-ACOUSTIC STIMULATION SYSTEM TO A PATIENT 有权
标题翻译：用于将电声刺激系统配给患者的方法和系统
公开(公告)号：US20150049890A1
公开(公告)日：2015-02-19
申请号：US14386330
申请日：2013-03-22
申请人： ADVANCED BIONICS AG
发明人： Smita S. Agrawal , Leonid M. Litvak
IPC分类号： H04R25/00 , A61N1/36
CPC分类号： A61N1/36036 , A61B5/04001 , A61B5/121 , A61N1/0541 , A61N1/37247 , H04R1/1008 , H04R25/00 , H04R25/505 , H04R25/554 , H04R25/606 , H04R25/70 , H04R2225/67 , H04R2460/03
摘要： An exemplary system includes 1) a stimulation management facility configured to direct an electro-acoustic stimulation (“EAS”) system to concurrently apply acoustic stimulation to a patient by way of a loudspeaker and electrical stimulation to the patient by way of an electrode located within a cochlea of the patient during a fitting session, and 2) a fitting facility communicatively coupled to the stimulation management facility and configured to detect, during the fitting session, an interaction between the acoustic stimulation and the electrical stimulation, and set, during the fitting session, one or more control parameters governing an operation of the EAS system based on the detected interaction. Corresponding systems and methods are also disclosed.
摘要翻译：示例性系统包括：1）刺激管理设备，其配置为引导电声刺激（“EAS”）系统，以通过扬声器向患者施加声学刺激，并通过位于内部的电极对患者进行电刺激在装配期间患者的耳蜗，以及2）通信地耦合到刺激管理设施并且被配置为在装配会话期间检测声刺激和电刺激之间的相互作用并且在配合期间设置的拟合设备会话，一个或多个基于检测到的交互来控制EAS系统的操作的控制参数。还公开了相应的系统和方法。

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