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71. 发明申请

US20080275628A1 METHOD AND APPARATUS FOR COMMUNICATING TRAFFIC INFORMATION 审中-公开
标题翻译：交通信息交流方法与装置
公开(公告)号：US20080275628A1
公开(公告)日：2008-11-06
申请号：US11743364
申请日：2007-05-02
申请人： Xiang Xu , Qi-Xiang Li , Zhao-Hui Li , Ke-Jiao Zhang
发明人： Xiang Xu , Qi-Xiang Li , Zhao-Hui Li , Ke-Jiao Zhang
IPC分类号： G06F19/00 , H04B1/02
CPC分类号： G08G1/096716 , G08G1/096741 , G08G1/096775 , H04L12/189 , H04L12/1895
摘要： A method and apparatus for communicating traffic information, that in certain embodiments performs the actions of associating (215) with a traffic group that corresponds to a traffic region, determining (220) at least one traffic related parameter of the mobile communication device while operating within the traffic region, and transmitting (235) to the traffic group a transmit traffic information message that includes the at least one traffic related parameter. In certain embodiments, the following actions are performed: receiving (225) one or more receive traffic information messages from mobile communication devices associated with the traffic group, wherein each receive traffic information message includes at least one traffic related parameter and preparing (240) a local traffic report using the receive traffic information messages.
摘要翻译：一种用于传送交通信息的方法和装置，在某些实施例中，执行将与业务区域相对应的业务组关联（215）的动作，确定（220）所述移动通信设备的至少一个业务相关参数，同时在所述业务区域，并且向所述业务组发送包括所述至少一个业务相关参数的发送业务信息消息（235）。在某些实施例中，执行以下动作：从与业务组相关联的移动通信设备接收（225）一个或多个接收业务信息消息，其中每个接收业务量信息消息包括至少一个业务相关参数并且准备（240）本地流量报告使用接收流量信息消息。

72. 发明申请

US20080146513A1 Synthetic Ion Channels 有权
标题翻译：合成离子通道
公开(公告)号：US20080146513A1
公开(公告)日：2008-06-19
申请号：US11959482
申请日：2007-12-19
申请人： Dan Yang , Xiang Li
发明人： Dan Yang , Xiang Li
IPC分类号： A61K38/07 , C07K17/02
CPC分类号： C07C239/20 , C07D213/63 , C07D213/79 , C07D213/81
摘要： Provided herein are self-assembling compounds that can form ion channels in lipid bilayers or cell membranes and ion-channel-forming compositions comprising the self-assembling compounds. Also provided are methods of making and using the ion channels formed from a plurality of molecules of the self-assembling compounds. Further, provided are methods of treating or preventing conditions and diseases that are related to the dysfunction of ion channels, including chloride channels.
摘要翻译：本文提供了可以在脂质双层或细胞膜中形成离子通道的自组装化合物和包含自组装化合物的离子通道形成组合物。还提供了制造和使用由多个自组装化合物分子形成的离子通道的方法。此外，提供了治疗或预防与离子通道功能障碍（包括氯化物通道）相关的病症和疾病的方法。

73. 发明授权

US07369544B2 Internet telephone system with hunting diversion 有权
标题翻译：互联网电话系统与狩猎转移
公开(公告)号：US07369544B2
公开(公告)日：2008-05-06
申请号：US10377067
申请日：2003-02-28
申请人： Xian-Xiang Li , Runlin Dong
发明人： Xian-Xiang Li , Runlin Dong
IPC分类号： H04L12/66
CPC分类号： H04M3/42374 , H04M3/42323 , H04M3/465 , H04M7/1205
摘要： A method of diverting a hunting function of a PSTN central office switch is provided. The method diverts a hunting function in the event a channel within a hunting group is available but a call can not be completed. The method comprises detecting a status of a plurality of user channels to determine whether all user channels associated with the hunting group are in use and providing a hunting diversion message to the PSTN central office switch in response to determining that all user channels associated with the hunting group are in use. The method also comprises detecting at least one user channel associated with the hunting group is available for an inbound call and providing a hunting enable message to the PSTN central office switch in response to determining that at least one user channel associated with the hunting group is available for an inbound call.
摘要翻译：提供了一种转移PSTN中心局交换机的寻线功能的方法。在寻线组中的频道可用但呼叫无法完成的情况下，该方法会转发寻线功能。该方法包括：检测多个用户信道的状态，以便响应于确定与寻线相关联的所有用户信道，确定与寻线组相关联的所有用户信道是否正在使用，并向PSTN中心局交换机提供寻呼转移消息组正在使用中。所述方法还包括：响应于确定与所述寻线组相关联的至少一个用户信道是可用的，检测与所述寻线组相关联的至少一个用户信道可用于入站呼叫并向所述PSTN中心局交换机提供寻呼使能消息用于入站呼叫。

74. 发明授权

US07368258B1 Devices and methods for profiling enzyme substrates 失效
公开(公告)号：US07368258B1
公开(公告)日：2008-05-06
申请号：US11447089
申请日：2006-06-06
申请人： Charles Bieberich , Xiang Li
发明人： Charles Bieberich , Xiang Li
IPC分类号： C12Q1/50
CPC分类号： C12Q1/00 , C12Q1/485 , G01N2500/02
摘要： The present invention relates to apparatus and methods for separating and detecting enzyme substrates using separation gels. For example, the apparatus and methods can be used to separate and detect kinase substrates for further analysis. The apparatus and methods can also be used to detect enzyme inhibitors, such as kinase inhibitors.

75. 发明申请

US20070191300A1 Methods for Modulating IKKalpha Activity 有权
标题翻译：调节IKKalpha活性的方法
公开(公告)号：US20070191300A1
公开(公告)日：2007-08-16
申请号：US11740438
申请日：2007-04-26
申请人： Jun Li , Xiang Li , Jianfei Yang , Kenneth Marcu
发明人： Jun Li , Xiang Li , Jianfei Yang , Kenneth Marcu
IPC分类号： A61K48/00 , C12Q1/48 , C07H21/02
CPC分类号： C12Q1/485 , A61K38/00 , C12N15/113 , C12N2310/14 , G01N2333/912 , G01N2500/00
摘要： A method for modulating NF-κB dependent gene transcription in a cell comprised of modulating IKKα protein activity in the cell. The present invention also provides siRNA compositions and methods thereof for modulating NF-κB dependent gene transcription.
摘要翻译：一种调节细胞中NF-κB依赖性基因转录的方法，包括调节细胞中的IKKα蛋白活性。本发明还提供了用于调节NF-κB依赖性基因转录的siRNA组合物及其方法。

76. 发明授权

US07235654B2 Methods for modulating IKKα activity 有权
标题翻译：调节IKKalpha活性的方法
公开(公告)号：US07235654B2
公开(公告)日：2007-06-26
申请号：US10730614
申请日：2003-12-08
申请人： Jun Li , Xiang Li , Jianfei Yang
发明人： Jun Li , Xiang Li , Jianfei Yang
IPC分类号： C07H21/02 , C07H21/04
CPC分类号： C12Q1/485 , A61K38/00 , C12N15/113 , C12N2310/14 , G01N2333/912 , G01N2500/00
摘要： A method for modulating NF-κB dependent gene transcription in a cell comprised of modulating IKKα protein activity in the cell. The present invention also provides siRNA compositions and methods thereof for modulating NF-κB dependent gene transcription.
摘要翻译：一种调节细胞中NF-κB依赖性基因转录的方法，包括调节细胞中的IKKα蛋白活性。本发明还提供了用于调节NF-κB依赖性基因转录的siRNA组合物及其方法。

77. 发明申请

US20070128648A1 Methods for the Identification of IKKalpha Function and other Genes Useful for Treatment of Inflammatory Diseases 审中-公开
标题翻译：用于鉴定IKKalpha功能和其他有助于治疗炎症疾病的基因的方法
公开(公告)号：US20070128648A1
公开(公告)日：2007-06-07
申请号：US11621029
申请日：2007-01-08
申请人： Jun Li , Adedeyo Hanidu , Xiang Li , Gregory Peet , Sheenah Mische , Kenneth Marcu
发明人： Jun Li , Adedeyo Hanidu , Xiang Li , Gregory Peet , Sheenah Mische , Kenneth Marcu
IPC分类号： A61K38/55 , C12Q1/68
CPC分类号： C12Q1/6883 , C12Q2600/158 , G01N33/5023
摘要： The invention provides a method for identifying genes involved in the NF-κB pathway comprised of the steps of determining the level of expression of a gene in an experimental sample obtained from the cells having deficient levels of a component of the NF-κB pathway; determining the level of expression of said gene in a control sample obtained from wild type cells having levels of a component of a biological pathway; selecting genes having a level of expression that are modulated in said experimental sample relative to said wild type sample. The invention also provides a method of treating inflammatory related diseases by modulating the activity of IKKα.
摘要翻译：本发明提供了鉴定涉及NF-κB途径的基因的方法，其包括确定从具有NF-κB途径成分水平不足的细胞获得的实验样品中基因表达水平的步骤; 确定从具有生物学途径成分水平的野生型细胞获得的对照样品中所述基因的表达水平; 选择具有相对于所述野生型样品在所述实验样品中调节的表达水平的基因。本发明还提供了通过调节IKKα的活性来治疗炎性相关疾病的方法。

78. 发明授权

US07187794B2 Noise treatment of low-dose computed tomography projections and images 失效
标题翻译：低剂量计算机断层扫描投影和图像的噪声处理
公开(公告)号：US07187794B2
公开(公告)日：2007-03-06
申请号：US10273927
申请日：2002-10-18
申请人： Zhengrong Liang , Hongbing Lu , Xiang Li
发明人： Zhengrong Liang , Hongbing Lu , Xiang Li
IPC分类号： G06K9/00
CPC分类号： G06T11/005 , G06T5/002 , G06T5/10 , G06T5/20 , G06T2207/10081 , G06T2207/20192 , G06T2207/30004 , Y10S378/901
摘要： A method for treating noise in low-dose computed tomography projections and reconstructed images comprises acquiring raw data at a low mA value, applying a domain specific filter in a sinogram domain of the raw data, and applying an edge preserving smoothing filter in an image domain of the raw data after filtering in the sinogram domain.
摘要翻译：一种用于处理低剂量计算机断层摄影投影和重建图像中的噪声的方法，包括以低mA值获取原始数据，在原始数据的正弦图域中应用域特定滤波器，以及在图像域中应用边缘保持平滑滤波器的原始数据在sinogram域过滤后。

79. 发明授权

US07097753B2 Dilute support frame for an EDI device 有权
标题翻译： EDI设备的稀释支持框架
公开(公告)号：US07097753B2
公开(公告)日：2006-08-29
申请号：US10630338
申请日：2003-07-30
申请人： Xiang Li , Gou-Lin Luo
发明人： Xiang Li , Gou-Lin Luo
IPC分类号： B01D61/46
CPC分类号： B01D61/52 , B01D61/46 , B01D63/10 , B01J47/08 , C02F1/4695
摘要： The dilute support frame is made up of interphase longitude and latitude bars that preferably are hollow. The bars can be rectangular, rectangular with a rounded end, half-circular, triangular, polygonal or any combination thereof. The bars are sized to support the ion exchange resin in the dilute channel adjacent the concentrate membrane bag. The support frame also assures fluent water flow in the dilute channel. The support frames are arrayed on the membranes with interphase aisle to save the frame arrays and make water flow fluently. The membrane envelopes in turn with the support frames as both are preferably wound to form the cylinder module, and is covered by one plastic protecting net. This new type of support frame can assure fluent water flow in dilute channels and convenient resin filling.
摘要翻译：稀释的支撑框架由优选为中空的相间经纬线组成。杆可以是矩形的，具有圆形端，半圆形，三角形，多边形或其任何组合的矩形。这些条的尺寸被设计成支持邻近浓缩膜袋的稀释通道中的离子交换树脂。支撑框架还保证了稀释通道中流畅的水流。支撑框架通过相间通道排列在膜上，以节省框架阵列，并使水流畅流动。薄膜依次包围支撑框架，两者都优选地被卷绕以形成气缸模块，并被一个塑料保护网覆盖。这种新型支撑框架可以确保稀疏通道中的流动水流动，树脂填充方便。

80. 发明申请

US20050202482A1 CD38 splice variants and uses thereof 有权
标题翻译： CD38剪接变体及其用途
公开(公告)号：US20050202482A1
公开(公告)日：2005-09-15
申请号：US11056106
申请日：2005-02-10
申请人： Jun Li , Xiang Li , Baerbel LoSacco , Zhenhao Qi
发明人： Jun Li , Xiang Li , Baerbel LoSacco , Zhenhao Qi
IPC分类号： A61K38/00 , A61K38/17 , C07K14/705 , C07K16/28 , C12Q1/68
CPC分类号： C07K14/70596 , A61K38/00
摘要： The invention provides for a substantially purified polypeptide referred to herein as CD38JL that is a CD38 splice variant comprised of the polypeptide of SEQ ID NO: 1 or a fragment thereof. The invention also provides methods for treating preventing and diagnosing disorders associated with expression of CD38JL.
摘要翻译：本发明提供了本文中称为CD38JL的基本上纯化的多肽，其是由SEQ ID NO：1的多肽或其片段组成的CD38剪接变体。本发明还提供了治疗预防和诊断与CD38JL表达相关的疾病的方法。

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