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71. 发明授权

US09297021B2 MtNIP regulated plants with significantly increased size and biomass 有权
标题翻译： MtNIP调节植物的大小和生物量
公开(公告)号：US09297021B2
公开(公告)日：2016-03-29
申请号：US13667257
申请日：2012-11-02
申请人： University of North Texas
发明人： Rebecca Dickstein , Mohammad Salehin , Rammyani Bagchi
IPC分类号： C12N15/82 , C07K14/415
CPC分类号： C12N15/8262 , C07K14/415 , C12N15/8261 , C12N15/827 , Y02A40/146
摘要： A composition and method for producing plants with increased biomass and growth characteristics, and plants which flower early relative to wild-type plants. The MtNIP gene is over-expressed in plants to increase biomass, growth, and early flowering. Other genes in the NRT1/PTR family may also be over-expressed to increase biomass, growth, and early flowering.
摘要翻译：用于生产具有增加的生物量和生长特性的植物的组合物和方法以及相对于野生型植物早期花期的植物。 MtNIP基因在植物中过表达，以增加生物量，生长和早期开花。 NRT1 / PTR家族中的其他基因也可能被过度表达以增加生物量，生长和早期开花。

72. 发明授权

US09218947B2 Nanomanipulation coupled nanospray mass spectrometry (NMS) 有权
标题翻译：纳米操纵耦合纳喷射质谱（NMS）
公开(公告)号：US09218947B2
公开(公告)日：2015-12-22
申请号：US14327927
申请日：2014-07-10
申请人： University of North Texas
发明人： Guido Fridolin Verbeck, IV
IPC分类号： H01J49/04 , G01N1/02 , H01J49/00 , G01N21/65 , H01J49/16
CPC分类号： H01J49/0027 , G01N21/65 , H01J49/0404 , H01J49/0459 , H01J49/167
摘要： A coupled nanomanipulation and nanospray mass spectrometry (NMS) system for single cell, single organelle, and ultra-trace molecular analysis is disclosed herein. The system primarily comprises a bio-workstation coupled to a NMS. The bio-workstation primarily comprises of a nanomanipulator stage with a plurality of nano-positioners attached to a cabinet with a piezo voltage source and a pressure injector. The present invention further describes a fingerprint lift method that when coupled with the system disclosed herein can be used for retrieval and analysis of trace amounts of drug and explosive residues. The system described herein has been used in the areas of trace and document analysis within the forensic field, trace fiber analysis, and electrostatic lifts for illicit drugs, as well as document and painting analysis.
摘要翻译：本文公开了用于单细胞，单细胞器和超微量分子分析的偶联纳米操纵和纳喷射质谱（NMS）系统。该系统主要包括耦合到NMS的生物工作站。生物工作站主要包括具有多个纳米定位器的纳米操纵器台，该纳米定位器用压电电压源和压力注射器连接到机柜。本发明进一步描述了当与本文公开的系统耦合时可用于追踪和分析痕量的药物和爆炸性残留物的指纹提升方法。本文描述的系统已被用于法医领域的追踪和文件分析，微量纤维分析和非法药物静电升降以及文件和绘画分析领域。

73. 发明申请

US20150351647A1 EFFECTIVE CPR PROCEDURE WITH REAL TIME EVALUATION AND FEEDBACK USING SMARTPHONES 审中-公开
标题翻译：有效的CPR程序与实时评估和反馈使用智商
公开(公告)号：US20150351647A1
公开(公告)日：2015-12-10
申请号：US14701222
申请日：2015-04-30
申请人： University of North Texas
发明人： Ramanamurthy Dantu , Neeraj Gupta , Vishnu Dantu , Zachary Morgan
IPC分类号： A61B5/024 , A61H31/00 , A61B5/00
CPC分类号： A61B5/02438 , A61B5/0013 , A61B5/0022 , A61B5/02416 , A61B5/68 , A61B5/6824 , A61B5/6898 , A61B2560/0223 , A61H31/007 , A61H2201/5097 , A61H2230/08 , G09B19/003 , G09B23/288 , G16H40/67 , H04M1/72538 , H04M2250/12
摘要： A method for performing CPR, comprising activating an application on one or more mobile phones having one or more sensors, placing one or more mobile phones on the finger of a subject to collect information about the subject, determining whether CPR is necessary based on the collected information about the subject, calibrating the sensors of the one or more mobile phones, placing the one or more mobile phones in a position on a hand of a user of the one or more mobile phones, administering chest compressions to the subject, activating a sensor of the one or more mobile phones, including an accelerometer sensor, to permit the application to capture information about the chest compression rate and displacement relating to movement of the chest of the subject, and transmitting the chest compression rate and displacement information of the subject to the emergency dispatcher using the mobile phone.
摘要翻译：一种用于执行CPR的方法，包括激活具有一个或多个传感器的一个或多个移动电话上的应用，将一个或多个移动电话放置在对象的手指上以收集关于所述对象的信息，基于所收集的信息来确定是否需要CPR 关于该主题的信息，校准一个或多个移动电话的传感器，将一个或多个移动电话放置在一个或多个移动电话的用户的手上的位置，向对象施加胸部按压，激活传感器一个或多个移动电话，包括加速度计传感器，以允许应用程序捕获关于胸部压缩率和与被检体的胸部运动相关的位移的信息，并将对象的胸部压缩率和位移信息传送到紧急调度员使用手机。

74. 发明申请

US20150329870A1 Methods for Elevating Fat/Oil Content in Plants 审中-公开
标题翻译：提高植物油脂含量的方法
公开(公告)号：US20150329870A1
公开(公告)日：2015-11-19
申请号：US14654320
申请日：2013-12-19
申请人： BOSTON MEDICAL CENTER CORPORATION , UNIVERSITY OF NORTH TEXAS
发明人： Vishwajeet Puri , Kent Chapman , Christopher James , Yingqi Cai
IPC分类号： C12N15/82 , C12N9/10 , C12N9/20 , C07K14/415
CPC分类号： C12N15/8247 , C07K14/415 , C12P7/6463
摘要： In some embodiments, the present invention provides a method of elevating lipid content in vegetative (non-seed) plant or algal cells, plant tissues, or whole plants by genetically modifying the plant or algae to express a protein or polypeptide associated with lipid metabolism (such as fat-specific protein 27) of animal origin or plant origin. Also provided are genetically-modified plant or algal cells, plant tissues, or whole plants with elevated cellular lipid content, expressing a protein or polypeptide associated with lipid metabolism (such as fat-specific protein 27) of animal (e.g. human) origin or plant origin.
摘要翻译：在一些实施方案中，本发明提供通过遗传修饰植物或藻类以表达与脂质代谢相关的蛋白质或多肽来提高营养（非种子）植物或藻类细胞，植物组织或整株植物中的脂质含量的方法（如脂肪特异性蛋白质27）的动物来源或植物来源。还提供了具有升高的细胞脂质含量的表达与动物（例如人）来源或植物的脂质代谢（例如脂肪特异性蛋白27）相关的蛋白质或多肽的遗传修饰植物或藻类细胞，植物组织或全植物起源。

75. 发明申请

US20150214156A1 MANUFACTURABLE SPIN AND SPIN-POLARON INTERCONNECTS 有权
标题翻译：可制造旋转和旋转极性互连
公开(公告)号：US20150214156A1
公开(公告)日：2015-07-30
申请号：US14606085
申请日：2015-01-27
申请人： THE UNIVERSITY OF NORTH TEXAS
发明人： Jeffry KELBER
IPC分类号： H01L23/532
CPC分类号： H01L29/0669 , H01L23/532 , H01L29/1606 , H01L29/4908 , H01L29/66742 , H01L43/14 , H01L2924/0002 , H01L2924/00
摘要： Manufacturable spin and spin-polaron interconnects are disclosed that do not exhibit the same increase in resistivity shown by Cu interconnects associated with decreasing linewidth. These interconnects rely on the transmission of spin as opposed to charge. Two types of graphene based interconnect approaches are explored, one involving the injection and diffusive transport of discrete spin-polarized carriers, and the other involving coherent spin polarization of graphene charge carriers due to exchange interactions with localized substrate spins. Such devices are manufacturable as well as scalable (methods for their fabrication exist, and the interconnects are based on direct growth, rather than physical transfer or metal catalyst formation). Performance at or above 300 K, as opposed to cryogenic temperatures, is the performance criteria.
摘要翻译：公开了可制造的自旋和自旋极化互连，其不显示与减少线宽相关联的Cu互连所示的电阻率相同的增加。这些互连依赖于自旋的传输而不是电荷。探讨了两种类型的基于石墨烯的互连方法，一种涉及离散自旋极化载流子的注入和扩散传输，另一种涉及石墨烯载流子的相干自旋极化，这是由于与局部衬底自旋的交换相互作用。这样的器件是可制造的以及可扩展的（存在其制造的方法，并且互连基于直接生长而不是物理转移或金属催化剂形成）。性能在300 K以上，与低温相反，是性能标准。

76. 发明申请

US20150045205A1 Controlled Deposition of Metal and Metal Cluster Ions by Surface Field Patterning in Soft-Landing Devices 有权
标题翻译：通过软着陆装置中的表面场图案控制金属和金属簇离子的沉积
公开(公告)号：US20150045205A1
公开(公告)日：2015-02-12
申请号：US14077911
申请日：2013-11-12
申请人： UNIVERSITY OF NORTH TEXAS
发明人： Guido Fridolin Verbeck, IV , Stephen Davila
IPC分类号： C23C14/22 , C23C14/04 , C23C14/12
CPC分类号： C23C14/221 , B81C2201/112 , B82B3/00 , B82Y30/00 , B82Y40/00 , C23C14/04 , C23C14/12 , C23C14/28 , C23C14/54
摘要： A soft-landing (SL) instrument for depositing ions onto substrates using a laser ablation source is described herein. The instrument of the instant invention is designed with a custom drift tube and a split-ring ion optic for the isolation of selected ions. The drift tube allows for the separation and thermalization of ions formed after laser ablation through collisions with an inert bath gas that allow the ions to be landed at energies below 1 eV onto substrates. The split-ring ion optic is capable of directing ions toward the detector or a landing substrate for selected components. The inventors further performed atomic force microscopy (AFM) and drift tube measurements to characterize the performance characteristics of the instrument.
摘要翻译：本文描述了使用激光烧蚀源将离子沉积到衬底上的软着陆（SL）仪器。本发明的仪器设计有用于分离选定离子的定制漂移管和分离环离子光学器件。漂移管允许通过与允许离子以低于1eV的能量降落到基底上的惰性浴气碰撞在激光烧蚀之后形成的离子的分离和热化。分裂环离子光学器件能够将离子引向检测器或用于选定部件的着陆衬底。本发明人进一步进行原子力显微镜（AFM）和漂移管测量以表征仪器的性能特征。

77. 发明授权

US08946692B2 Graphene (multilayer) boron nitride heteroepitaxy for electronic device applications 有权
标题翻译：石墨烯（多层）氮化硼异质外延电子器件应用
公开(公告)号：US08946692B2
公开(公告)日：2015-02-03
申请号：US13678827
申请日：2012-11-16
申请人： University of North Texas
发明人： Jeffry A Kelber
IPC分类号： H01L29/06 , H01L29/15 , H01L31/0256 , H01L29/08 , H01L35/24 , H01L51/00 , B32B9/04 , B82Y30/00 , B82Y40/00 , C01B31/04 , C23C16/26 , C23C16/34 , H01L21/02 , H01L21/8238 , H01L23/532
CPC分类号： B32B9/041 , B82Y30/00 , B82Y40/00 , C01B32/186 , C23C16/26 , C23C16/342 , H01L21/02112 , H01L21/0228 , H01L21/823871 , H01L23/53276 , H01L45/00 , H01L2924/0002 , Y10T428/24355 , Y10T428/24967 , Y10T428/261 , H01L2924/00
摘要： Disclosed is a substrate-mediated assembly for graphene structures. According to an embodiment, long-range ordered, multilayer BN(111) films can be formed by atomic layer deposition (ALD) onto a substrate. The subject BN(111) films can then be used to order carbon atoms into a graphene sheet during a carbon deposition process.
摘要翻译：公开了用于石墨烯结构的基板介导的组件。根据实施例，可以通过原子层沉积（ALD）在衬底上形成长程有序的多层BN（111）膜。然后可以在碳沉积过程中将目标BN（111）膜用于将碳原子排列成石墨烯片。

78. 发明申请

US20140296249A1 4-PHENYLPIPERAZINE DERIVATIVES WITH FUNCTIONALIZED LINKERS AS DOPAMINE D3 RECEPTOR SELECTIVE LIGANDS AND METHODS OF USE 审中-公开
标题翻译：具有功能性连接子的4-苯基哌嗪衍生物作为DOPAMINE D3受体选择性配体和使用方法
公开(公告)号：US20140296249A1
公开(公告)日：2014-10-02
申请号：US14266076
申请日：2014-04-30
申请人： The United States of America, as Represented by the Secretary, Department of Health and Human Serv , THE UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE AT FORT WORTH
发明人： Amy Hauck Newman , Peter Grundt , George C. Cyriac , Robert Luedtke , Jianjing Cao
IPC分类号： C07D307/85 , G01N33/566 , C07D209/42 , C07D213/56 , C07D295/13
CPC分类号： C07D307/85 , C07D209/42 , C07D209/48 , C07D213/56 , C07D213/64 , C07D213/81 , C07D213/89 , C07D295/092 , C07D295/096 , C07D295/13 , C07D295/145 , C07D333/70 , G01N33/566
摘要： Dopamine D3 receptor antagonists and partial agonists are known to modulate the reinforcing and drug-seeking effects induced by cocaine and other abused substances. By introducing functionality into the butylamide linking chain of the 4-phenylpiperazine class of ligands, improved D3 receptor affinity and selectivity, as well as water solubility, is achieved. A series of linking-chain derivatives are disclosed wherein functionality such as OH, OAc, and cis or trans-cyclopropyl groups have been introduced into the linking chain. In general, these modifications are well tolerated at D3 receptors and achieve high selectivity over D2 and D4 receptors.
摘要翻译：已知多巴胺D3受体拮抗剂和部分激动剂调节可卡因和其他滥用物质诱导的增强和寻求药物作用。通过将功能性引入4-苯基哌嗪类配体的丁酰胺连接链中，实现了改善的D3受体亲和力和选择性以及水溶性。公开了一系列连接链衍生物，其中诸如OH，OAc和顺式或反式 - 环丙基的官能团已被引入连接链。通常，这些修饰在D3受体上具有良好的耐受性，并且相对于D2和D4受体实现高选择性。

79. 发明申请

US20140173777A1 METHODS FOR ELEVATING FAT/OIL CONTENT IN PLANTS 审中-公开
标题翻译：在植物中提取脂肪/油含量的方法
公开(公告)号：US20140173777A1
公开(公告)日：2014-06-19
申请号：US13830012
申请日：2013-03-14
申请人： BOSTON MEDICAL CENTER CORPORATION , UNIVERSITY OF NORTH TEXAS
发明人： Vishwajeet PURI , Kent CHAPMAN , Christopher JAMES
IPC分类号： C12N15/82
CPC分类号： C12N15/8247 , C07K14/415 , C12P7/6463
摘要： In some embodiments, the present invention provides a method of elevating lipid content in vegetative (non-seed) plant or algae cells, plant tissues, or whole plants by genetically modifying the plant or algae to express a lipid droplet-associated protein or polypeptide (such as fat-specific protein 27) of mammalian origin. Also provided are genetically-modified plant or algae cells, plant tissues, or whole plants with elevated cellular lipid content, expressing a lipid droplet-associated protein or polypeptide (such as fat-specific protein 27) of mammalian (e.g. human) origin.
摘要翻译：在一些实施方案中，本发明提供了通过遗传修饰植物或藻类以表达脂滴相关蛋白或多肽来提高营养（非种子）植物或藻类细胞，植物组织或整株植物中的脂质含量的方法（例如哺乳动物来源的脂肪特异性蛋白质27）。还提供了表达哺乳动物（例如人）来源的脂滴相关蛋白或多肽（例如脂肪特异性蛋白27）的经遗传修饰的植物或藻类细胞，植物组织或具有升高的细胞脂质含量的全植物。

80. 发明申请

US20130252859A1 SOLID LUBRICATING, HARD AND FRACTURE RESISTANT COMPOSITES FOR SURFACE ENGINEERING APPLICATIONS 审中-公开
标题翻译：表面工程应用的固体润滑，硬质和抗断裂复合材料
公开(公告)号：US20130252859A1
公开(公告)日：2013-09-26
申请号：US13769787
申请日：2013-02-18
申请人： University of North Texas
发明人： Sundeep Gopagoni , Thomas W. Scharf , Rajarshi Banerjee , Jaimie S. Tiley
IPC分类号： F16C33/04
CPC分类号： C10M7/00 , C10M103/02 , C10M2201/0413 , C10N2210/08 , C10N2220/082 , C10N2230/06
摘要： A method and composition for producing a monolithic hybrid composite consisting of a composite matrix, a reinforcement phase, and a solid/self-lubrication phase. The composition may comprise a graphite (“C”) phase and a titanium carbide (“TiC”) phase in a nickel (“Ni”) matrix. The process may include the step of blending pure Ni and pure titanium (“Ti”) powders with Ni-coated graphite powder using Laser Engineered Net Shaping (“LENS”). The novel composite, when achieved with an optimum chemical and structural phase ratio, exhibits a balance of high hardness, fracture toughness, and low friction/wear,
摘要翻译：一种用于生产由复合基体，增强相和固体/自润滑相组成的单片混合复合材料的方法和组合物。组合物可以在镍（“Ni”）基质中包含石墨（“C”）相和碳化钛（“TiC”）相。该方法可以包括使用激光工程净化（“LENS”）将纯Ni和纯钛（“Ti”）粉末与Ni涂覆的石墨粉末混合的步骤。新型复合材料在达到最佳化学结构相比时，具有高硬度，断裂韧性和低摩擦/磨损的平衡，

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