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    • 71. 发明申请
    • NOVEL DIHYDRONAPHTHALENE COMPOUND AND USE THEREOF
    • 新型二氢萘酚化合物及其用途
    • US20100249400A1
    • 2010-09-30
    • US12675331
    • 2008-09-11
    • Isamu Shiina
    • Isamu Shiina
    • C07D403/12C07D413/12C07C211/09C07D401/12
    • C07D295/088C07C217/24C07C2602/10
    • Disclosed is a compound represented by the formula (I) below as a dihydronaphthalene compound having a chemical structure which is excellent in production efficiency when compared with lasofoxifene and nafoxidine. This compound is useful as a proteasome inhibitor and/or an antitumor agent. (In the formula, two —(CH2)l—N(R1) (R2) groups represent a same substituent; R1 and R2 each represents a hydrogen atom, or a same or different alkyl group; or alternatively, R1 and R2 may combine together to form a monocyclic heterocyclic ring with a nitrogen atom having them or additionally together with one or more atoms selected from an oxygen atom, a sulfur atom and a nitrogen atom; R3, R4 and R5 each represents one or more substituents selected from a hydrogen atom, an alkyl group, an acyl group, an alicyclic group, an aromatic group, a halogen atom, an acyloxy group, a cyano group and a nitro group; l represents an integer of 2-5; n represents an integer of 1-4; m represents an integer of 1-5; and q represents an integer of 1-3.)
    • 公开了下述式(I)表示的化合物,其具有与拉索昔芬和nafoxidine相比具有优异的生产效率的化学结构的二氢化合物。 该化合物可用作蛋白酶体抑制剂和/或抗肿瘤剂。 (式中,二 - (CH 2)1 -N(R 1)(R 2)基团表示相同的取代基; R 1和R 2各自表示氢原子或相同或不同的烷基;或者,R 1和R 2可以组合 一起形成具有氮原子的单环杂环,或者另外与一个或多个选自氧原子,硫原子和氮原子的原子一起形成; R3,R4和R5各自表示一个或多个选自氢的取代基 原子,烷基,酰基,脂环族基团,芳香族基团,卤素原子,酰氧基,氰基和硝基; l表示2-5的整数; n表示1- 4; m表示1-5的整数,q表示1-3的整数。)
    • 74. 发明申请
    • Anti-Reflection Structure Body, Method Of Producing The Same And Method Of Producing Optical Member
    • 防反射结构体及其制造方法及其制造方法
    • US20090323189A1
    • 2009-12-31
    • US12310016
    • 2007-08-09
    • Jun Taniguchi
    • Jun Taniguchi
    • G02B1/11C23C14/48
    • G02B1/118
    • An anti-reflection structure body comprises a base member which is made of glassy carbon and at a surface of which is formed an anti-reflection structure including a cluster of minute projections each having a diameter that contracts towards a tip thereof. The minute projections preferably have an average height of from 200 nm to 3000 nm and an average maximum diameter of from 50 nm to 300 nm, and an average pitch of from 50 nm to 300 nm. An anti-reflection structure body which is easily produced, capable of achieving an anti-reflection effect near to non-reflection, and capable of providing the minute structure even to a member having a high melting point such as quartz glass or the like by transfer or the like can be provided.
    • 防反射结构体包括由玻璃碳制成的基底构件,其表面形成有防反射结构,该防反射结构包括具有朝向其尖端收缩的直径的微小突起簇。 微小突起的平均高度优选为200nm〜3000nm,平均最大直径为50nm〜300nm,平均间距为50nm〜300nm。 一种抗反射结构体,其易于制造,能够实现接近无反射的抗反射效果,并且能够通过转印对具有高熔点的构件(例如石英玻璃等)提供均匀的微小结构 或类似物。