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71. 发明授权

US09519885B2 System and method for linking a web-based resource with an electronic medical record 有权
标题翻译：将基于网络的资源与电子医疗记录相关联的系统和方法
公开(公告)号：US09519885B2
公开(公告)日：2016-12-13
申请号：US13584915
申请日：2012-08-14
申请人： Karl M. Kochendorfer , Jared S. Coberly
发明人： Karl M. Kochendorfer , Jared S. Coberly
IPC分类号： G06Q10/10 , G06Q50/24 , G06F9/445
CPC分类号： G06Q10/10 , G06F8/65 , G06F19/00 , G06Q50/24
摘要： A data processing system and method that, in some cases, include an EMR system and a web server. In some cases, the EMR system includes a plurality of electronic medical records for a plurality of patients. One or more of the electronic medical records may include a URL or HTTP Post message that defines a path to a web-based resource, such as a treatment algorithm or medical calculator. In some embodiments, the URL and/or HTTP Post message is constructed based on information in a patient's medical record.
摘要翻译：在某些情况下，包括EMR系统和Web服务器的数据处理系统和方法。在一些情况下，EMR系统包括用于多个患者的多个电子医疗记录。一个或多个电子医疗记录可以包括定义到诸如治疗算法或医疗计算器的基于网络的资源的路径的URL或HTTP Post消息。在一些实施例中，URL和/或HTTP Post消息是基于患者医疗记录中的信息构建的。

72. 发明申请

US20160347621A1 SYNTHESIS OF BORANE COMPOUNDS 审中-公开
标题翻译：硼烷化合物的合成
公开(公告)号：US20160347621A1
公开(公告)日：2016-12-01
申请号：US15116365
申请日：2015-02-03
申请人： ALEXANDER VALENTINOVICH SAFRONOV , SATISH SUBRAY JALISATGI , MARION FREDERICK HAWTHORNE
发明人： ALEXANDER VALENTINOVICH SAFRONOV , SATISH SUBRAY JALISATGI , MARION FREDERICK HAWTHORNE
IPC分类号： C01B35/00 , C07F5/02 , C07F5/04
CPC分类号： C01B35/00 , C01B35/121 , C01B35/14 , C07F5/022 , C07F5/04
摘要： The present invention is directed to a process for the synthesis of alkali metal tetrahydroborates-10B and amine borane-10B precursors, such as sodium tetrahydroborate-10B and triethylamine borane-10B.
摘要翻译：本发明涉及合成碱金属四氢硼酸盐-10B和胺硼烷-10B前体的方法，例如四氢硼酸钠-IBB和三乙胺硼烷-IBB。

73. 发明授权

US09508007B2 Method of predicting crop yield loss due to N-deficiency 有权
标题翻译：预测由于N缺乏导致的作物产量损失的方法
公开(公告)号：US09508007B2
公开(公告)日：2016-11-29
申请号：US14886712
申请日：2015-10-19
申请人： The Curators of the University of Missouri
发明人： Peter Clifton Scharf , Victoria Cacnio Hubbard
IPC分类号： G06K9/00 , G06T7/40 , A01C21/00 , G06Q50/02 , G06Q10/04 , G06Q10/06
CPC分类号： G06K9/00657 , A01C21/007 , G06K9/0063 , G06K9/2018 , G06K9/4642 , G06K9/4652 , G06K9/52 , G06Q10/04 , G06Q10/06315 , G06Q50/02 , G06T7/90 , G06T2207/10024 , G06T2207/10036 , G06T2207/30188
摘要： A method for determining the yield loss of a crop using remote sensor data is described. The yield loss is determined using the reflectivity of light by the crop canopy measured from remote sensor data such as an aerial photograph that is digitized and spatially referenced to the field's longitude and latitude. Pixel values from the aerial photograph, expressed relative to pixel values from well fertilized areas of the field, are transformed to yield losses using a linear transformation that was developed using empirical data. A similar method is described to determine recommended nitrogen fertilization rates for the crop fields. The yield loss data is useful for nitrogen fertilization management, as it allows a producer of crops to weigh the expense of fertilization against the loss of revenue due to yield loss.
摘要翻译：描述了使用远程传感器数据确定作物的产量损失的方法。产量损失是使用由远程传感器数据测量的作物冠层的光的反射率确定的，例如数字化并且空间参考场的经度和纬度的空中照片。通过使用经验数据开发的线性变换，将来自空间照片的像素值相对于场受精区域的像素值转换为产生损失。描述了类似的方法来确定作物田的推荐氮肥率。产量损失数据对于氮肥管理是有用的，因为它允许作物生产者权衡施肥费用与产量损失造成的收入损失。

74. 发明申请

US20160340350A1 Separation Method for Active Pharmaceutical Ingredients from Excipients 有权
标题翻译：赋形剂活性药物成分的分离方法
公开(公告)号：US20160340350A1
公开(公告)日：2016-11-24
申请号：US15137868
申请日：2016-04-25
申请人： Jerry L. Atwood
发明人： Jerry L. Atwood
IPC分类号： C07D417/12 , B03B5/32 , C07D211/22
CPC分类号： C07D417/12 , C07D211/22
摘要： The present invention provides a method for physically separating the active pharmaceutical ingredient (API) from the excipients in a pharmaceutical formulation before the API is fully characterized by standard techniques. The presently disclosed method is based on making use of the difference in density of the API and that of the excipients. In the method, the API is not dissolved, nor is the crystal form of the API changed.
摘要翻译：本发明提供了在通过标准技术完全表征API之前，将药物制剂中的活性药物成分（API）与赋形剂物理分离的方法。目前公开的方法是基于API的使用和赋形剂的密度差异。在该方法中，API不溶解，API的晶体形式也不变。

75. 发明授权

US09486747B2 Nanocomposite membranes with advanced antifouling properties under visible light irradiation 有权
标题翻译：纳米复合膜在可见光照射下具有先进的防污性能
公开(公告)号：US09486747B2
公开(公告)日：2016-11-08
申请号：US14821390
申请日：2015-08-07
申请人： Baolin Deng , Jun Yin
发明人： Baolin Deng , Jun Yin
IPC分类号： B01D39/00 , B01D39/14 , B29C65/20 , B29C47/00 , B01D69/08 , B01D65/08 , B01D69/02 , B01D69/14 , B01D71/34
CPC分类号： B01D69/08 , B01D65/08 , B01D69/02 , B01D69/148 , B01D71/34 , B01D2321/343
摘要： Nitrogen doped TiO2 (N—TiO2) is used to fabricate Poly(vinyledene fluoride) (PVDF)/N—TiO2 mixed matrix hollow fiber membranes (HFMs) through a phase inversion method to improve filtration efficiencies and antifouling properties. The membranes performances were evaluated based on the water permeability, humic acid (HA) rejection and antifouling properties. Resulting membranes showed brown color and improved hydrophilicity, especially under light irradiation. When compared to original PVDF and PVDF/P25 membrane, mixed matrix membranes containing N—TiO2 nanoparticles (NPs) showed clear photocatalytic activities under visible light irradiation. Also, membrane performance assessments indicated that PVDF/N—TiO2 membranes possessed enhanced water flux, similar HA rejection (e.g., above 96%) and improved fouling resistance with PVDF membranes as a control. The results demonstrate the potential of the suggested methodology for development of membranes with improved water permeability and superior antifouling properties based on photo-degradation processes and photo-induced hydrophilicity enhancement driven by solar light as a renewable energy source.
摘要翻译：氮掺杂TiO2（N-TiO2）用于通过相转化法制备聚（氟乙烯）氟化物（PVDF）/ N-TiO2混合基质中空纤维膜（HFM），以提高过滤效率和防污性能。膜性能基于透水性，腐殖酸（HA）排斥和防污性能进行评估。所得膜显示褐色和改善的亲水性，特别是在光照射下。与原始PVDF和PVDF / P25膜相比，含有N-TiO2纳米粒子（NP）的混合基质膜在可见光照射下显示出明显的光催化活性。此外，膜性能评估表明，PVDF / N-TiO2膜具有增强的水通量，类似的HA排斥（例如高于96％），并且以PVDF膜作为对照改善了耐污垢性。结果表明了基于光降解过程和由太阳光作为可再生能源驱动的光诱导亲水性增强的改进的水渗透性和优异的防污性质的膜的开发方法的潜力。

76. 发明授权

US09456890B2 Scaffold for bone and tissue repair in mammals 有权
公开(公告)号：US09456890B2
公开(公告)日：2016-10-04
申请号：US13740365
申请日：2013-01-14
申请人： The Curators of the University of Missouri
发明人： Delbert E. Day , Steven B. Jung
IPC分类号： A61F2/02 , A61L27/10 , A61L27/56 , A61L27/44 , A61L27/50 , A61L27/60 , A61F2/30
CPC分类号： A61F2/02 , A61F2/30965 , A61F2002/30448 , A61F2002/30766 , A61F2002/3092 , A61F2220/005 , A61L27/10 , A61L27/446 , A61L27/50 , A61L27/56 , A61L27/60 , A61L2430/02 , A61L2430/30 , A61L2430/34 , C08L67/04 , C08L33/12
摘要： A mammalian tissue scaffold and method for making a tissue scaffold including a rigid scaffold body of biocompatible glass fibers bonded together and in special alignment to define open channels within the scaffold to allow fluid flow into and within the scaffold.

77. 发明授权

US09427483B2 Radioisotope trithiol complexes 有权
标题翻译：放射性同位素三硫醇复合物
公开(公告)号：US09427483B2
公开(公告)日：2016-08-30
申请号：US14679520
申请日：2015-04-06
申请人： Silvia S. Jurisson , Cathy S. Cutler , Anthony J. Degraffenreid
发明人： Silvia S. Jurisson , Cathy S. Cutler , Anthony J. Degraffenreid
IPC分类号： A61K51/04 , A61K51/10
CPC分类号： A61K51/0478 , A61K51/1093
摘要： The present invention is directed to a series of stable radioisotope trithiol complexes that provide a simplified route for the direct complexation of radioisotopes present in low concentrations. In certain embodiments, the complex contains a linking domain configured to conjugate the radioisotope trithiol complex to a targeting vector. The invention is also directed to a novel method of linking the radioisotope to a trithiol compound to form the radioisotope trithiol complex. The inventive radioisotope trithiol complexes may be utilized for a variety of applications, including diagnostics and/or treatment in nuclear medicine.
摘要翻译：本发明涉及一系列稳定的放射性同位素三硫醇复合物，其提供用于以低浓度存在的放射性同位素的直接络合的简化途径。在某些实施方案中，复合物含有被配置成将放射性同位素三硫醇复合物与靶向载体缀合的连接结构域。本发明还涉及将放射性同位素与三硫醇化合物连接以形成放射性同位素三硫醇络合物的新方法。本发明的放射性同位素三硫醇复合物可用于各种应用，包括核医学中的诊断和/或治疗。

78. 发明授权

US09395353B2 Nanopore-facilitated single molecule detection of nucleic acid 有权
标题翻译：纳米孔促进核酸分子检测
公开(公告)号：US09395353B2
公开(公告)日：2016-07-19
申请号：US13810105
申请日：2011-07-14
申请人： Li-Qun Gu , Yong Wang , Kai Tian
发明人： Li-Qun Gu , Yong Wang , Kai Tian
IPC分类号： G01N27/327 , G01N33/487 , C12Q1/68
CPC分类号： C12Q1/6825 , C12Q1/6886 , C12Q2600/178 , G01N33/48721 , C12Q2523/307 , C12Q2525/161 , C12Q2525/207 , C12Q2565/631
摘要： The present invention provides a new and improved oligonucleotide detection method based on the nanopore technology with a probe containing a complementary sequence to the target oligonucleotide and a terminal extension at the probe's 3′ terminus, 5′ terminus, or both termini. The improved nanopore sensor with the probe enables sensitive, selective, and direct detection, differentiation and quantification of target oligonucleotides such as miRNAs. The inventive detection method may also be employed as a non-invasive and cost-effective diagnostic method for cancer detection based on miRNA levels in the patient's blood sample.
摘要翻译：本发明提供了一种新的和改进的基于纳米孔技术的寡核苷酸检测方法，其中探针含有靶寡核苷酸的互补序列，探针的3'末端，5'末端或两个末端具有末端延伸。具有探针的改进的纳米孔传感器能够灵敏，选择性和直接检测，分化和定量靶寡核苷酸，如miRNA。本发明的检测方法也可以用作基于患者血液样品中的miRNA水平的用于癌症检测的非侵入性和成本有效的诊断方法。

79. 发明申请

US20160166459A1 INSTRUMENT-ASSISTED SOFT TISSUE MOBILIZATION TOOL 审中-公开
标题翻译：仪器辅助软组织移动工具
公开(公告)号：US20160166459A1
公开(公告)日：2016-06-16
申请号：US14969862
申请日：2015-12-15
申请人： Jaya Ghosh , Ellie Koehly , Yaw Sarpong , Roger de la Torre , Jonathon Buehler , Brett Hayes , Teresa Graff , Katherina Chen
发明人： Jaya Ghosh , Ellie Koehly , Yaw Sarpong , Roger de la Torre , Jonathon Buehler , Brett Hayes , Teresa Graff , Katherina Chen
IPC分类号： A61H1/00
CPC分类号： A61H7/001 , A61H2201/0153 , A61H2201/1695
摘要： A tool for use in assisting soft tissue mobilization and bodily tissue amelioration, such as stimulation of superficial tissue, deep tissue mobilization, breaking up scar tissue, and soft tissue massaging, are described. The tool comprises a device for application to bodily tissue that includes a body having a substantially teardrop shape in a vertical section. In a longitudinal aspect, the body includes a first and a second portion. The first portion of the device corresponds at least in part to a substantially bulbous handle part of the teardrop shape of the vertical section and is adapted for ease of grasping and manipulation at the first end. The second portion of the device corresponds at least in part to a substantially tapered converging double-beveled linear edge of the teardrop shape of the vertical section and is adapted for facilitated application of the device to bodily tissue at the second end.
摘要翻译：描述了用于辅助软组织动员和身体组织改善的工具，例如刺激表面组织，深层组织移动，分解瘢痕组织和软组织按摩。该工具包括用于应用于身体组织的装置，其包括在垂直部分中具有基本上泪滴形状的主体。在纵向方面，主体包括第一和第二部分。该装置的第一部分至少部分地对应于垂直部分的泪滴形状的大致球形手柄部分，并且适于在第一端容易抓握和操纵。装置的第二部分至少部分地对应于垂直部分的泪滴形状的基本上锥形的收敛双斜面线性边缘，并且适于便于将装置应用于第二端的身体组织。

80. 发明授权

US09351966B2 Composition comprising a combination of omeprazole and lansoprazole, and a buffering agent, and methods of using same 有权
标题翻译：包含奥美拉唑和兰索拉唑组合的组合物和缓冲剂及其使用方法
公开(公告)号：US09351966B2
公开(公告)日：2016-05-31
申请号：US14490531
申请日：2014-09-18
申请人： The Curators of the University of Missouri
发明人： Jeffrey O. Phillips
IPC分类号： A61K31/4439 , A61K9/20 , A61K31/415 , A61K31/44
CPC分类号： A61K31/4439 , A61K9/2009 , A61K9/2054 , A61K9/2059 , A61K31/415 , A61K31/44 , A61K2300/00
摘要： The present disclosure relates to pharmaceutical compositions comprising omeprazole, lansoprazole and sodium bicarbonate. Methods of using such compositions are also provided.
摘要翻译：本公开涉及包含奥美拉唑，兰索拉唑和碳酸氢钠的药物组合物。还提供了使用这些组合物的方法。

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