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61. 发明申请

US20140271706A1 COMPOSITIONS AND METHODS FOR UTILIZATION OF ALGAL COMPOUNDS 有权
标题翻译： ALGAL化合物的组合物和方法
公开(公告)号：US20140271706A1
公开(公告)日：2014-09-18
申请号：US14025772
申请日：2013-09-12
申请人： James Astwood , Michelle L. Collins , Brian Connolly
发明人： James Astwood , Michelle L. Collins , Brian Connolly
IPC分类号： A23L1/30 , A61K31/202 , A61K31/232 , A61K31/661 , A61K31/7028 , A61K36/02 , A61K31/201
CPC分类号： A23L17/60 , A21D2/165 , A23D9/00 , A23L2/04 , A23L33/105 , A23L33/115 , A23L33/12 , A23V2002/00 , A23V2200/308 , A23V2200/326 , A23V2200/328 , A23V2250/187 , A23V2250/1876 , A23V2250/202 , A61K31/20 , A61K31/201 , A61K31/202 , A61K31/231 , A61K31/661 , A61K31/683 , A61K31/7012 , A61K31/7028 , A61K36/02 , C11B3/001 , C11C1/02 , C11C3/08 , C12N15/8247 , C12P7/6427 , A61K2300/00 , A23V2250/1868
摘要： Provided herein are exemplary compositions, products, and capsules utilizing POA, EPA, blends of POA and EPA, total algal oil compositions, and/or whole biomass compositions in methods of inhibiting inflammation including in cardiovascular disease, diabetes, obesity, stroke, metabolic syndromes, dementia, Alzheimer's disease, and/or cancer. The exemplary compositions, products, and capsules may be orally, topically, intravenously, and/or subcutaneously administered. The exemplary compositions herein may be used as feed, food, food supplements, beverages, beverage supplements, nutritional products, products for athletic performance, pharmaceutical products, and/or medical products for mammalian use, including humans.
摘要翻译：本文提供了在抑制炎症的方法中使用POA，EPA，POA和EPA的混合物，总藻类组合物和/或整个生物质组合物的示例性组合物，产品和胶囊，包括在心血管疾病，糖尿病，肥胖症，中风，代谢综合征，痴呆，阿尔茨海默病和/或癌症。示例性组合物，产品和胶囊可以是口服，局部，静脉内和/或皮下施用的。本文的示例性组合物可用作饲料，食品，食品添加剂，饮料，饮料补充剂，营养产品，用于运动表现的产品，药物产品和/或哺乳动物使用的医疗产品，包括人类。

62. 发明授权

US08795679B2 Pharmaceutical and cosmetic use of extracts from algae obtainable from saline hot water sources 有权
标题翻译：从盐水热水源获得的藻类提取物的药物和化妆品用途
公开(公告)号：US08795679B2
公开(公告)日：2014-08-05
申请号：US12299749
申请日：2007-05-07
申请人： Sigurbjorn Einarsson , Asa Brynjolfsdottir , Jean Krutmann
发明人： Sigurbjorn Einarsson , Asa Brynjolfsdottir , Jean Krutmann
IPC分类号： A61K36/02
CPC分类号： A61Q19/08 , A61K8/99 , A61Q17/00 , A61Q19/00
摘要： The invention provides the use of extracts from algae for cosmetic and/or medical treatment of skin, including improving and enhancing the skin-barrier, anti-aging treatment and photo-protective treatment. The invention is based on the finding that extracts from algae obtainable from saline hot water sources exhibit a multi-faceted biological effect useful in the cosmetic and/or therapeutic treatment of skin for the above purposes. Specifically, it has been shown that such algae extracts induce markers (involucrin, filaggrin and transglutaminase-1) for skin barrier formation in keratinocytes, induce collagen expression in dermal fibroblasts and inhibit UVA-induced up-regulation of photo-aging markers (matrix metalloproteinase MMP-1 and cytokine IL-6).
摘要翻译：本发明提供藻类提取物用于皮肤的化妆和/或医学治疗的用途，包括改善和增强皮肤屏障，抗衰老治疗和光保护治疗。本发明基于以下发现：从盐水热水源获得的藻类提取物出于上述目的，可用于化妆品和/或治疗皮肤的多面生物学效应。具体地说，已经表明，这样的藻类提取物诱导角质形成细胞中的皮肤屏障形成的标志物（外皮蛋白，丝胶蛋白和转谷氨酰胺酶-1），诱导真皮成纤维细胞中的胶原表达并抑制UVA诱导的光老化标记物（基质金属蛋白酶 MMP-1和细胞因子IL-6）。

63. 发明授权

US08791060B2 Composition and use of phyto-percolate for treatment of disease 有权
标题翻译：植物渗滤液的组成和用途用于治疗疾病
公开(公告)号：US08791060B2
公开(公告)日：2014-07-29
申请号：US12897574
申请日：2010-10-04
申请人： Tiffany Thomas , Michael Tempesta
发明人： Tiffany Thomas , Michael Tempesta
IPC分类号： C07K14/00 , A61K36/02 , A61K31/715 , A61K38/16
CPC分类号： A61K38/16 , A61K31/715 , A61K36/02
摘要： This invention relates generally to a method of preparation of a phyto-percolate that is derived from fresh water mixture including algae. The phyto-percolate is believed to contain an enzyme having proteolytic activity. The invention further relates to the use of the phyto-percolate in a variety of disease state.
摘要翻译：本发明一般涉及从含有藻类的淡水混合物得到的植物渗透液的制备方法。植物渗透液被认为含有具有蛋白水解活性的酶。本发明还涉及在各种疾病状态下植物渗透液的使用。

64. 发明授权

US08758769B2 Composition for preventing and treating acetaminophen inducing liver injury comprising the protein extract from Porphyra yezoensis 有权
标题翻译：用于预防和治疗诱导肝损伤的对乙酰氨基酚的组合物，其包含来自紫菜属（Porphyra yezoensis）的蛋白质提取物
公开(公告)号：US08758769B2
公开(公告)日：2014-06-24
申请号：US12083195
申请日：2007-08-28
申请人： Taek-Jeong Nam , Mi-Jin Kwon , Hye-Jung Hwang
发明人： Taek-Jeong Nam , Mi-Jin Kwon , Hye-Jung Hwang
IPC分类号： A61K36/02 , A61K8/97
CPC分类号： A61K8/975 , A61K38/011 , Y10S435/814 , Y10S514/893
摘要： Disclosed is a composition for preventing and treating acetaminophen induced liver injury including the protein extracted from Porphyra yezoensis. The protein(s), separated and purified from hot water extracts of Porphyra yezoensis, having the molecular weight of 14 kDa measured by sodium dodecyl sulfate polyacrylamide gel electrophoresis, has an excellent effect for inhibiting the oxidative injury of liver tissue and cell apoptosis of liver cells induced by acetaminophen.
摘要翻译：公开了一种用于预防和治疗对乙酰氨基酚诱发的肝损伤的组合物，包括从紫菜属中提取的蛋白质。通过十二烷基硫酸钠聚丙烯酰胺凝胶电泳测定的具有14kDa分子量的紫菜紫菜热水提取物中分离纯化的蛋白质对抑制肝组织氧化损伤和肝细胞凋亡具有极好的作用对乙酰氨基酚诱导的细胞。

65. 发明授权

US08722057B2 Method for producing β-carotene rich Dunaliella powder 有权
标题翻译：富含胡萝卜素的杜氏盐藻的生产方法
公开(公告)号：US08722057B2
公开(公告)日：2014-05-13
申请号：US13462003
申请日：2012-05-02
申请人： Ami Ben-Amotz , Nobuo Mori
发明人： Ami Ben-Amotz , Nobuo Mori
IPC分类号： A61K39/385 , C12N1/12 , A61K36/02
CPC分类号： A61K36/05 , A23L17/60 , A23L33/105 , A61K2236/331
摘要： In a step of producing a powder product of the alga belonging to the genus Dunaliella, a pH adjusting step is included in which an alga belonging to the genus Dunaliella is allowed to be in a basic state of pH 9.5 or higher. According to the method, it is possible to provide dried Dunaliella powder containing β-carotene at a high content by suppressing degradation of β-carotene as an active ingredient while decreasing each of the total pheophorbide amount and the existing pheophorbide amount to a predetermined value or less, even if the total pheophorbide amount and the existing pheophorbide amount of the cultured algae belonging to the genus Dunaliella are higher in summer.
摘要翻译：在制造属于杜氏盐藻属的藻类的粉末产物的步骤中，包括属于杜氏盐藻属的藻类处于pH9.5或更高的碱性状态的pH调节步骤。根据该方法，可以通过抑制β-胡萝卜素作为活性成分的降解，以高含量提供含有β-胡萝卜素的干燥杜氏盐藻粉，同时将总脱镁叶酸量和现有的脱镁叶酸量降低至预定的价值以下，即使属于杜氏盐藻属的培养藻类的总脱镁叶酸量和现存的偏磷酸盐量在夏季较高。

66. 发明申请

US20140093554A1 NUTRITIONAL COMPOSITIONS WITH LARGE LIPID GLOBULE SIZE 审中-公开
标题翻译：具有大脂肪全球尺寸的营养成分
公开(公告)号：US20140093554A1
公开(公告)日：2014-04-03
申请号：US13914405
申请日：2013-06-10
申请人： N.V. Nutricia
发明人： Eline Marleen VAN DER BEEK , Gelske SPEELMANS , Antonie VAN BAALEN , Annemarie OOSTING , Günther BOEHM
IPC分类号： A23L1/30 , A61K9/14 , A61K31/575 , A61K31/688 , A61K35/66 , A61K31/20 , A61K35/60 , A61K36/02 , A61K36/06 , A23L1/29 , A61K31/202
CPC分类号： A61K36/02 , A23L33/115 , A23L33/12 , A23L33/40 , A23V2002/00 , A61K9/1276 , A61K9/14 , A61K31/20 , A61K31/202 , A61K31/575 , A61K31/688 , A61K35/20 , A61K35/60 , A61K35/66 , A61K36/06 , A23V2200/306 , A23V2250/18 , A61K2300/00
摘要： The present invention relates to a nutritional composition for infants and/or toddlers comprising a lipid component which has a large lipid globule size. The composition can be used to increase bone mineral content and/or bone mass density.
摘要翻译：本发明涉及包含脂质组分的婴儿和/或幼儿的营养组合物，所述脂质组分具有大的脂质球尺寸。该组合物可用于增加骨矿物质含量和/或骨质量密度。

67. 发明授权

US08637096B2 Compositions and method for enhancing insulin activity 失效
标题翻译：用于增强胰岛素活性的组合物和方法
公开(公告)号：US08637096B2
公开(公告)日：2014-01-28
申请号：US13524485
申请日：2012-06-15
申请人： Curtis C. Stojan
发明人： Curtis C. Stojan
IPC分类号： A61K36/45 , A61K36/906 , A61K36/736 , A61K36/82 , A61K36/886 , A61K36/02
CPC分类号： A61K36/00 , A61K9/0034 , A61K9/08 , A61K36/54 , A61K38/28 , A61K2300/00
摘要： A new treatment for individuals suffering from type 2 diabetes. The formulation used in the treatment includes a mixture of a thiazoleineione, an insulin, cinnamon bark extract, and at least one synergistic supplement selected from the group consisting of blueberry leaf extract, cranberry extract, kelp extract, sugar sea beet extract, acerola berry extract; ginger root extract, black cherry extract, green tea extract, Irish moss extract, aloe vera extract, and Stevia leaf extract. The thiazoleineione is preferably pioglitazone. The insulin is preferably an Insulin Aspart of rDNA origin. It is preferred that the cinnamon bark extract and synergistic supplement be in the form of a liquid concentrate.
摘要翻译：对2型糖尿病患者的新治疗。用于治疗的制剂包括噻唑啉酮，胰岛素，肉桂皮提取物和至少一种选自蓝莓叶提取物，蔓越莓提取物，海带提取物，糖甜菜提取物，黑莓果实提取物的协同增效剂的混合物 ; 姜根提取物，黑樱桃提取物，绿茶提取物，爱尔兰苔藓提取物，芦荟提取物和甜菊叶提取物。噻唑啉酮优选吡格列酮。胰岛素优选为来源于rDNA的胰岛素天冬氨酸。优选的是肉桂皮提取物和协同增效剂是液体浓缩物的形式。

68. 发明授权

US08586053B2 Composition and use of phyto-percolate for treatment of disease 有权
标题翻译：植物渗滤液的组成和用途用于治疗疾病
公开(公告)号：US08586053B2
公开(公告)日：2013-11-19
申请号：US12067735
申请日：2006-04-20
申请人： Tiffany Thomas
发明人： Tiffany Thomas
IPC分类号： A61K36/02
CPC分类号： A61K38/02 , A61K31/715 , A61K36/02
摘要： This invention relates generally to a method of preparation of a phyto-percolate that is derived from fresh water mixture including algae. The invention further relates to the use of the phyto-percolate in a variety of disease states. The phyto-percolate is believed to contain an activity that induces the reduction of soluble and insoluble fibrin. Further, the phyto-percolate is believed to reduce oxidative stress in the body.
摘要翻译：本发明一般涉及从含有藻类的淡水混合物得到的植物渗透液的制备方法。本发明还涉及植物浸膏在各种疾病状态中的应用。据信植物渗透液含有诱导可溶性和不溶性纤维蛋白降低的活性。此外，植物渗透液被认为可以减少体内的氧化应激。

69. 发明授权

US08512764B2 Cosmetic use of skin cell autophagy activators 有权
公开(公告)号：US08512764B2
公开(公告)日：2013-08-20
申请号：US13133046
申请日：2009-12-04
申请人： Jean Paufique
发明人： Jean Paufique
IPC分类号： A61K36/00 , A61K36/06 , A61K36/02 , A61K36/752
CPC分类号： A61K8/97 , A61K8/99 , A61K36/04 , A61K36/062 , A61K36/185 , A61K36/42 , A61K36/48 , A61K36/752 , A61Q19/08
摘要： The object of the invention is the use in a cosmetic composition of an effective amount of at least one cutaneous cell autophagy activator as a cosmetic active ingredient. The invention also relates to cosmetic compositions that include at least one cutaneous cell autophagy activator as a cosmetic active ingredient 5 and a cosmetic process for detoxifying skin and/or for preventing or combating cutaneous aging.

70. 发明授权

US08440209B2 Adhesive for medical applications and means for haemostasis 有权
标题翻译：用于医疗应用的粘合剂和止血手段
公开(公告)号：US08440209B2
公开(公告)日：2013-05-14
申请号：US13037850
申请日：2011-03-01
申请人： Andreas Speitling , Philip Procter , Joachim Schomburg , Christian Schultz , Wolf-Dieter Jülich , Ulrike Lindequist , Frieder Schauer , Annett Mikolasch , Katrin Manda
发明人： Andreas Speitling , Philip Procter , Joachim Schomburg , Christian Schultz , Wolf-Dieter Jülich , Ulrike Lindequist , Frieder Schauer , Annett Mikolasch , Katrin Manda
IPC分类号： A61K9/00 , A61K31/74 , A61K31/765 , A61K36/02 , A01N65/00 , A01N63/02
CPC分类号： C09J175/04 , A61L24/043 , C08G18/10 , C08G18/428 , C08G18/6446 , C08L89/00 , C09J189/00 , Y10T428/2982 , C08L67/04 , C08G18/64
摘要： The invention relates to adhesives for medical applications and methods of their preparation and use.
摘要翻译：本发明涉及用于医疗应用的粘合剂及其制备和使用方法。

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