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61. 发明授权

US4788700A Fluorescent X-ray analyzing method of solution specimen and specimen sampler used for the method 失效
标题翻译：用于该方法的溶液样品和样品取样器的荧光X射线分析方法
公开(公告)号：US4788700A
公开(公告)日：1988-11-29
申请号：US928657
申请日：1986-11-05
申请人： Shigetoshi Kurozumi , Tadahiro Abe , Hideo Maruyama , Noriko Yasui
发明人： Shigetoshi Kurozumi , Tadahiro Abe , Hideo Maruyama , Noriko Yasui
IPC分类号： G01N23/22 , G01N23/223 , H05G1/00
CPC分类号： G01N23/2202
摘要： For analyzing the solution specimen according to the fluorescent X-ray analyzing method, a certain quantity of solution specimen to be analyzed is impregnated into a thin porous sheet, for example by dripping method, and the sheet is dried for evaporating the solvent. Held on an appropriate holder, for example, the sheet is placed in the vacuum atmosphere or the atmosphere of helium gas, so that the primary X-rays are irradiated and the wavelength or the intensity of the fluorescent X-rays generated from the solute remained in the sheet may be detected. The concentration of the solution may be changed by concentration or by dilution, so that an adequate intensity of the fluorescent X-ray may be generated. The specimen sampler is made of porous sheet material, to which the solution specimen to be analyzed is impregnated and dried to remain only the solute of the solution in the sheet. To the circumferential edge of the sheet is attached a circular edge of a support, so that the central portion of the porous sheet is sufficiently spaced from the circumferentially provided support.
摘要翻译：为了根据荧光X射线分析法对溶液样品进行分析，将一定量的待分析溶液试样浸渍在例如滴加法的薄多孔片材中，干燥以蒸发溶剂。例如，在适当的保持器上，将片材放置在真空气氛或氦气气氛中，从而照射初级X射线，并且保留从溶质产生的荧光X射线的波长或强度可能检测到纸张。可以通过浓缩或稀释来改变溶液的浓度，从而可以产生足够强度的荧光X射线。样品取样器由多孔片材制成，待分析的溶液样品被浸渍和干燥，以仅保留片材中溶液的溶质。在片材的圆周边缘附着有支撑件的圆形边缘，使得多孔片材的中心部分与周向设置的支撑件充分地间隔开。

62. 发明授权

US4719120A Detection of oxygen in thin films 失效
标题翻译：检测薄膜中的氧气
公开(公告)号：US4719120A
公开(公告)日：1988-01-12
申请号：US913793
申请日：1986-09-29
申请人： Arold K. Green , Robert H. Hammond
发明人： Arold K. Green , Robert H. Hammond
IPC分类号： C23C14/52 , G01N23/22 , B05D5/12
CPC分类号： C23C14/52 , G01N23/2202
摘要： A method for determining the presence, during deposition of a first thin m layer, of a substance which escapes when the layer is cooled and transferred from its deposition environment for analysis to determine the presence of the substance. The layer is first covered with a second layer of a material which captures the escaping substance. This second layer is then covered with a cap layer of a substance which seals the second layer against contamination, as from the atmosphere during transfer. The layered structure, with the escaped substance retained in the second layer, is then analyzed, as by sputter depth profiling and Auger electron spectroscopy, to determine the presence in the second layer of the escaped substance and thus determine the presence of this substance during deposition of the first layer.
摘要翻译：一种用于确定在沉积第一薄膜层期间存在当该层被冷却并从其沉积环境转移以确定物质的存在时逸出的物质的存在的方法。该层首先用覆盖逸出物质的第二层材料覆盖。然后，该第二层被覆盖有物质的盖层，所述物质的密封层与传递期间的大气密封第二层以防污染。然后通过溅射深度分布和俄歇电子能谱法分析保留在第二层中的逃逸物质的分层结构，以确定在逸出物质的第二层中的存在，从而确定沉积期间该物质的存在的第一层。

63. 发明授权

US4680716A Automatic method and apparatus for dosing samples 失效
标题翻译：自动计量样品的方法和装置
公开(公告)号：US4680716A
公开(公告)日：1987-07-14
申请号：US676448
申请日：1984-11-29
申请人： Alain Naudi
发明人： Alain Naudi
IPC分类号： G01N23/223 , G01N1/28 , G01N1/44 , G01N23/22 , G06F15/46
CPC分类号： G01N1/44 , G01N23/2202
摘要： In an automatic sample-dosing method and machine a "bead" is formed which is to be analysed by X-ray fluorescence with, the mixture being dosed in three stages: feeding with flux material (lithium tetraborate), feeding with sample material, and feeding with flux material in such a way that the sample material does not stick to the wall of the weighing pan by making use of the relevant angles of repose.
摘要翻译：在自动采样计量方法和机器中，形成要通过X射线荧光分析的“珠粒”，混合物分三个阶段进料：喂入助焊剂材料（四硼酸锂），喂入样品材料，以及以这样的方式供给助焊剂材料，使得样品材料通过利用相关的休止角度不粘附在称重盘的壁上。

64. 发明授权

US3890089A Homogeneous fusion system and method 失效
标题翻译：均匀融合系统和方法
公开(公告)号：US3890089A
公开(公告)日：1975-06-17
申请号：US40709473
申请日：1973-10-17
申请人： ALUMINUM CO OF AMERICA
发明人： MATOCHA CHARLES K
IPC分类号： G01N1/04 , F27B17/02 , G01N1/44 , F27B3/06
CPC分类号： F27B17/02 , G01N1/286 , G01N1/44 , G01N23/2202 , G01N23/223 , G01N2001/2866
摘要： A fusion system is provided whereby material in comminuted form or the like may be automatically fused under conditions which provide a homogeneously fused sample which then may be analyzed by analytical techniques to determine content of the material. The apparatus for carrying out the fusion provides control of the initial heating time, fusion time, and cooling time, as well as controlling the mixing or blending of the sample material during the fusion to ensure the homogenuity of the mixture.
摘要翻译：提供了一种融合系统，其中粉碎形式的材料等可以在提供均匀融合的样品的条件下自动融合，然后可以通过分析技术分析以确定材料的含量。用于进行熔化的装置提供初始加热时间，融合时间和冷却时间的控制，以及在熔化期间控制样品材料的混合或混合，以确保混合物的均匀度。

65. 发明公开

US20240288391A1 SYSTEM TO INSPECT, MODIFY OR ANALYZE A REGION OF INTEREST OF A SAMPLE BY CHARGED PARTICLES, SET OF SYSTEMS TO INSPECT, MODIFY OR ANALYZE A REGION OF INTEREST OF A SAMPLE AND METHOD TO INSPECT, MODIFY OR ANALYZE A REGION OF INTEREST OF A SAMPLE BY CHARGED PARTICLES 审中-公开
公开(公告)号：US20240288391A1
公开(公告)日：2024-08-29
申请号：US18653555
申请日：2024-05-02
申请人： Carl Zeiss SMT GmbH
发明人： John A. Notte , Mark D. DiManna , Jeffrey Sauer , Terry Griffin
IPC分类号： G01N23/2251 , G01N23/2202
CPC分类号： G01N23/2251 , G01N23/2202 , G01N2223/309 , G01N2223/3301
摘要： A system inspects, modifies or analyzes a region of interest of a sample via charged particles. A detector device of the system produces a pixel image having horizontal and vertical pixel resolutions. A charged particle deflection device produces a scanning charged particle beam in a scanning region. The deflection device has horizontal and vertical deflection units controlled by a digital to analog converter having a digital resolution larger than the horizontal pixel resolution and/or the vertical pixel resolution. An operator control interface of the system selects an assignment between respective image pixels of a desired pixel image and digital inputs of the DAC to produce horizontal and/or vertical deflection signals to guide the charged particle beam to the location of the respective image pixel. A reliable image of a sample can be obtained even when there is zooming or panning within an accessible region of the sample.

66. 发明公开

US20240288389A1 CHARGED PARTICLE ASSESSMENT SYSTEM AND METHOD 审中-公开
公开(公告)号：US20240288389A1
公开(公告)日：2024-08-29
申请号：US18660165
申请日：2024-05-09
申请人： ASML NETHERLANDS B.V.
发明人： Marco Jan-Jaco WIELAND , Erwin SLOT , Peter Paul HEMPENIUS , Niels Johannes Maria BOSCH
IPC分类号： G01N23/2202 , B08B5/00 , B08B7/00 , G01N23/2251
CPC分类号： G01N23/2202 , B08B5/00 , B08B7/0035 , G01N23/2251 , G01N2223/6116 , G01N2223/646
摘要： The embodiments of the present disclosure provide a charged particle assessment system for projecting a beam of charged particles towards a sample. The system comprises a sample holder configured to hold a sample; a charged particle optical system configured to project a beam of charged particles from a charged particle source downbeam towards the sample and comprising a cleaning target; and a cleaning device. The cleaning device is configured to supply cleaning medium in a cleaning flow towards the cleaning target incident on the cleaning target so that the cleaning flow approaches the cleaning target from downbeam of the cleaning target, and to stimulate the cleaning medium at or near the cleaning target such that the cleaning medium cleans at least a portion of the surface of the cleaning target.

67. 发明公开

US20230349847A1 METHOD FOR DETERMINING PROTEIN STRUCTURE USING CRYO-ELECTRON MICROSCOPY 审中-公开
公开(公告)号：US20230349847A1
公开(公告)日：2023-11-02
申请号：US18307936
申请日：2023-04-27
申请人： SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY CHINESE ACADEMY OF SCIENCES
发明人： Horst VOGEL , Zhili RAO , Xueying WANG , Xiaokang ZHANG , Shuguang YUAN , Huawei ZHANG
IPC分类号： G01N23/2251 , G01N23/2202
CPC分类号： G01N23/2251 , G01N23/2202
摘要： A method for determining a protein structure using cryo-electron microscopy, including: enabling a target protein to contain a tag; enabling a resulting target containing the tag to bind a scaffold protein to form a complex between the target protein and the scaffold protein; and performing single-particle imaging using the cryo-electron microscopy to determine a structure of the target protein in complex with the scaffold protein. The scaffold protein is any one of streptavidin, avidin, or derivatives thereof. The tag is configured for selectively binding to the scaffold protein. The tag is one selected from the group consisting of: a biotin tag, comprising a biotin; a biotinylated protein or polypeptide tag, comprising a protein sequence and a biotin covalently linked to the protein sequence; a Strep-tag; and a biotinylated or strep-tagged antibody, or antibody Fab fragment, or single-chain antibody.

68. 发明公开

US20230333032A1 SAMPLE HOLDER FOR DETECTION OF HYDROGEN PERMEATION AND HYDROGEN PERMEATION AND DIFFUSION PATH OBSERVATION DEVICE 审中-公开
公开(公告)号：US20230333032A1
公开(公告)日：2023-10-19
申请号：US18028862
申请日：2021-08-19
申请人： NATIONAL INSTITUTE FOR MATERIALS SCIENCE
发明人： Akiko Nakamura , Taro Yakabe , Naoya Miyauchi
IPC分类号： G01N23/2204 , G01N23/2251 , G01N23/2202 , H01J37/20
CPC分类号： G01N23/2204 , G01N23/2251 , G01N23/2202 , H01J37/20 , H01J2237/2002
摘要： The sample holder 30 comprises: a holder body 31 for holding the sample 17; an electrolyte introduction chamber 31b provided with an opening 31c that opens to a measurement region 17a of the sample; a retainer plate 33, which is provided with a through-hole 33a corresponding to the measurement region of the sample, for retaining the sample from the electron source side around the through-hole to sandwich the sample airtightly with the holder body; double sealing members 32 arranged between the surface of the holder body and the sample so as to surround the periphery of the measurement region of the sample; a differential exhaust pipe 35, which opens to a space between the sealing members on the surface of the holder body, for exhaust the space through the opening; and electrodes 19 for electrolysis made up of a bias application electrode 19a and an opposing electrode 36.

69. 发明公开

US20230333031A1 SAMPLE BLOCK AND SAMPLE BLOCK HOLDER 审中-公开
公开(公告)号：US20230333031A1
公开(公告)日：2023-10-19
申请号：US18008071
申请日：2021-06-02
申请人： ROCKTYPE LTD
发明人： Henrik Nilsen OMMA
IPC分类号： G01N23/2202 , G01N23/2251
CPC分类号： G01N23/2202 , G01N23/2251 , G01N2223/418
摘要： A sample block (1) and a sample block holder (51) for use in the analysis of material samples, such as rock drill cuttings (24), using a scanning electron microscope. The sample block (1) is provided with a profile that facilitates alignment within the sample block holder (51) that ensures that a sample block (1) that is inspected and then subsequently re-inspected remains in the same orientation for the first and second inspections. Areas of interest of the rock drill cuttings (24) identified in the first inspection can thus be reliably inspected during the second inspection because the possibility of the sample block (1) being submitted in a different orientation has been removed.

70. 发明公开

US20230296797A1 Multi-Physical Field Imaging Method and System Based on PET-CT and DAS 审中-公开
公开(公告)号：US20230296797A1
公开(公告)日：2023-09-21
申请号：US18321746
申请日：2023-05-22
申请人： Institute of Geology and Geophysics, Chinese Academy of Sciences
发明人： Zizhuo Ma , Yibo Wang , Yikang Zheng , Shaojiang Wu , Qingfeng Xue
IPC分类号： G01N23/2206 , G01N29/14 , G01N29/22 , G01N23/046 , G01N23/2202
CPC分类号： G01N23/2206 , G01N23/046 , G01N23/2202 , G01N29/14 , G01N29/227
摘要： Embodiments of the present disclosure provide a multi-physical field imaging method based on PET-CT and DAS, comprising: wrapping distributed acoustic sensors on a surface of a non-metallic sample to be tested, and then placing them in a pressure device; loading triaxial pressures; preparing a tracer fluid; pumping the tracer fluid into the non-metallic sample; collecting PET images and CT images of internal structure of the non-metallic sample, meanwhile, monitoring internal acoustic emission events of the non-metallic sample in real time; combining the PET images with the CT images, to obtain PET/CT images; locating the acoustic emission events, and obtaining occurrence time and spatial location of internal structural perturbations; and analyzing a mechanism of fluid-solid coupling effect in the non-metallic sample under loaded stress. The imaging method and system of the present disclosure can accurately and reliably image the fluid-solid coupling process in the material.

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