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61. 发明授权

US5921939A Device for monitoring measurement electrodes to detect the presence of faults in electrode, leads and in the connection of the electrodes to a patient 失效
标题翻译：用于监测测量电极以检测电极，引线中的故障以及电极与患者的连接的装置
公开(公告)号：US5921939A
公开(公告)日：1999-07-13
申请号：US24973
申请日：1998-02-06
申请人： Peter Danielsson , Thomas Ohlsson
发明人： Peter Danielsson , Thomas Ohlsson
IPC分类号： A61B5/0408 , A61B5/0424 , A61B5/053 , A61B5/0428
CPC分类号： A61B5/0424 , A61B5/0531 , A61B5/0535
摘要： In a device for monitoring measurement electrodes, attached to a patient in order to pick up physiological measurement signals, and a neutral electrode and associated leads at the same time as physiological measurement signals are picked up, each measurement electrode is connected to an input terminal on its associated measurement amplifier. A test signal generator is arranged to generate a pure AC signal, without any direct current component, across the neutral electrode attached to a patient during the pickup of measurement signals.
摘要翻译：在用于监测测量电极的装置中，为了拾取生理测量信号而连接到患者，以及在拾取生理测量信号的同时中性电极和相关联的引线，每个测量电极连接到输入端上其相关的测量放大器。测试信号发生器被布置成在拾取测量信号期间跨越附接到患者的中性线产生没有任何直流分量的纯AC信号。

62. 发明授权

US5520191A Myocardial ischemia and infarction analysis and monitoring method and apparatus 失效
标题翻译：心肌缺血和梗死分析及监测方法及装置
公开(公告)号：US5520191A
公开(公告)日：1996-05-28
申请号：US320511
申请日：1994-10-07
申请人： Per Karlsson , Gunilla Lundahl , Michael Oljemark , Johan Ubby
发明人： Per Karlsson , Gunilla Lundahl , Michael Oljemark , Johan Ubby
IPC分类号： A61B5/00 , A61B5/04 , A61B5/0424 , A61B5/044 , A61B5/0452 , A61B5/0464 , A61B5/0472
CPC分类号： A61B5/061 , A61B5/0006 , A61B5/04011 , A61B5/04028 , A61B5/04525 , A61B5/0472 , A61B5/7475 , A61B5/0424 , A61B5/0464 , A61B5/7217 , A61B5/7221
摘要： A cardiac monitoring method and system provides advanced ischemia and infarction analysis and monitoring. Advanced calculations are performed on ECG signals to obtain parameter values relating to myocardial ischemia and infarction. Dominant heart beats are averaged to form a smooth beat, which is analyzed to determine the parameter values continuously and in real-time. The result of each analyzed time interval is presented as points in a trend graph on a monitoring display. All calculations are performed on-line and the trend curves are updated immediately.
摘要翻译：心脏监测方法和系统提供先进的缺血和梗死分析和监测。对ECG信号进行高级计算，以获得与心肌缺血和梗死相关的参数值。平衡主心心跳以形成平滑节拍，进行分析以连续和实时地确定参数值。每个分析的时间间隔的结果在监视显示器的趋势图中表示为点。所有计算都在线执行，趋势曲线将立即更新。

63. 发明授权

US5020541A Apparatus for sensing lead and transthoracic impedances 失效
公开(公告)号：US5020541A
公开(公告)日：1991-06-04
申请号：US464348
申请日：1990-01-12
申请人： Arthur R. Marriott
发明人： Arthur R. Marriott
IPC分类号： A61B5/0424 , A61B5/053
CPC分类号： A61B5/0535 , A61B5/0424
摘要： A method and apparatus for use with medical electrode systems that sense the integrity of lead connections and patient transthoracic impedance is provided. In an ECG electrode application, a carrier circuit (12) produces two carrier signals (S.sub.C1 and S.sub.C2) that are out of phase with each other. The S.sub.C1 signal is applied to an RA lead through a terminating impedance (Z1). The S.sub.C2 signal is applied to LA, LL and V leads through terminating impedances (Z2, Z3, and Z4). Each of the S.sub.C1 and S.sub.C2 carrier signals comprises a lead impedance frequency component (S.sub.LI) and an impedance respiration frequency component (S.sub.IR). First stage amplifiers (A1, A2, and A3) located in an ECG preamplifier (13) amplify the difference between a lead voltage on the RA lead (V.sub.RA) and lead voltages on the LA, LL, and V leads (V.sub.LA, V.sub.LL and V.sub.V). High pass filters (F1, F2 and F3) remove patient ECG signals from the outputs of A1, A2 and A3 to produce first stage output voltages (V.sub.1, V.sub.2 and V.sub.5). The V.sub.1, V.sub.2 and V.sub.5 voltages are demodulated by a demodulator circuit (18). Lead impedance demodulators (DM1, DM2 and DM3) are clocked by a lead impedance control signal (S.sub.A) that has the same frequency as the S.sub.LI component so that the outputs of DM1, DM2 and DM3 are lead impedance-related voltages (V.sub.L1, V.sub.L2 and V.sub.L5). V.sub.2 is also demodulated by an impedance respiration demodulator (DM4). DM4 is clocked by an impedance respiration control signal (S.sub.B) that has the same frequency as the S.sub.IR component so that the output of DM4 is a transthoracic impedance-related voltage V.sub.T. V.sub.T is amplified by an operational amplifier (OA10) to produce an impedance respiration-related voltage (V.sub.R). The ECG preamplifier (13) and the demodulator circuit (18) include fast DC restoration circuits (66, 68, 70 and 71) that use switched capacitor integrators (76) to restore ECG outputs (V.sub.E1, V.sub.E2, and V.sub.E5) and the V.sub.R voltage to nominal values when a DC offset has occurred.

64. 发明授权

US4993423A Method and apparatus for differential lead impedance comparison 失效
标题翻译：差分引线阻抗比较的方法和装置
公开(公告)号：US4993423A
公开(公告)日：1991-02-19
申请号：US464380
申请日：1990-01-12
申请人： John R. Stice
发明人： John R. Stice
IPC分类号： A61B5/0424 , G01R17/10
CPC分类号： A61B5/0424 , G01R17/105
摘要： A differential lead impedance comparison apparatus (10) senses lead impedance and compensates for patient-to-patient and electrode variability. A bridge circuit (12) is connected to one end of electrode conductors (22, 24 and 26) in an ECG Leads I configuration. The other end of the conductors (22, 24 and 26) are connected to a patient (18) via electrodes (RA, LA and LL). Leads formed in part by RA, LA and LL and the respective conductors (22, 24 and 26) have lead impedances (R.sub.b, R.sub.a, and R.sub.c). Constant current sources (11, 12 and 13) are connected to the conductors (22, 24 and 26) and supply constant AC currents (I.sub.1, I.sub.2 and I.sub.3). A first bridge output voltage (V.sub.M) is produced by I.sub.1 and a combination 32 of R.sub.a, R.sub.b, and R.sub.c. A second bridge output voltage (V.sub.P) is produced by I.sub.2 and a combination 34 of R.sub.a, R.sub.b, and R.sub.c. A differential amplifier circuit (14) differentially amplifies the V.sub.M and V.sub.P voltages to produce differential voltages (V.sub.OM and V.sub.OP). Demodulators (DM1 and DM2) demodulate V.sub.OM and V.sub.OP to produce differential impedance voltages (V.sub.1M and V.sub.1P). A first comparator (OA3) changes states and produces a high logic output when V.sub.1M equals or exceeds a first threshold level (V.sub.TH1). A second comparator (OA4) changes states and produces a high logic output when V.sub.1P equals or exceeds a second threshold level (V.sub.TH2). An exclusive OR gate (G1) produces a high logic output (V.sub.OUT) when one and only one of OA3 or OA4 produce a high logic output.
摘要翻译：差分引线阻抗比较装置（10）感测引线阻抗并补偿患者与患者和电极的变异性。桥接电路（12）以ECG引线I配置连接到电极导体（22,24和26）的一端。导体（22,24和26）的另一端通过电极（RA，LA和LL）连接到患者（18）。由RA，LA和LL部分形成的引线和相应的导体（22,24和26）具有引线阻抗（Rb，Ra和Rc）。恒流源（11,12和13）连接到导体（22,24和26），并提供恒定的交流电流（I1，I2和I3）。第一桥输出电压（VM）由I1和Ra，Rb和Rc的组合32产生。第二桥输出电压（VP）由I2和Ra，Rb和Rc的组合34产生。差分放大器电路（14）差分地放大VM和VP电压以产生差分电压（VOM和VOP）。解调器（DM1和DM2）解调VOM和VOP以产生差分阻抗电压（V1M和V1P）。当V1M等于或超过第一阈值电平（VTH1）时，第一比较器（OA3）改变状态并产生高逻辑输出。当V1P等于或超过第二阈值电平（VTH2）时，第二比较器（OA4）改变状态并产生高逻辑输出。当OA3或OA4中只有一个产生高逻辑输出时，异或门（G1）产生高逻辑输出（VOUT）。

65. 发明授权

US4424816A Neurological monitoring device test circuitry 失效
标题翻译：神经监测装置测试电路
公开(公告)号：US4424816A
公开(公告)日：1984-01-10
申请号：US258587
申请日：1981-04-29
申请人： Alfred S. Callahan , James S. Rhodes , Timothy L. Johnson , John G. Durden
发明人： Alfred S. Callahan , James S. Rhodes , Timothy L. Johnson , John G. Durden
IPC分类号： A61B5/0424 , A61B5/0476 , A61B5/04
CPC分类号： A61B5/0476 , A61B5/0424
摘要： Circuitry for use with a brain wave monitoring device is provided for selectively monitoring the impedance of the current paths in the patient's scalp concurrently with brain wave monitoring, and circuitry for self-testing the system for proper functioning.
摘要翻译：用于脑波监测装置的电路被提供用于与脑波监测同时选择性地监测患者头皮中的电流路径的阻抗，以及用于自我测试系统以用于正常功能的电路。

66. 发明授权

US4338951A Magnetically coupled isolation interface circuit 失效
标题翻译：磁耦合隔离接口电路
公开(公告)号：US4338951A
公开(公告)日：1982-07-13
申请号：US179614
申请日：1980-08-19
申请人： Thomas V. Saliga
发明人： Thomas V. Saliga
IPC分类号： A61B5/0424 , A61B5/0476 , A61B5/00
CPC分类号： A61B5/0424 , A61B5/0476 , Y10S128/908
摘要： A pair of toroidally wound cores are maintained in a generally parallel, vertical, spaced apart relationship by a tubular insulating member passing through the toroid centers. The tubular member insulates the windings from a coupling loop which passes through the tube and which closes outside the toroidal windings. One winding is the primary of the isolation circuit, connecting the source of signals through a FET device to ground, and the other winding is secondary winding, which is also connected to ground through a FET, and which is coupled to a utilization device through a low pass filter. The FET devices are synchronously pulsed at a frequency above the signal frequency and the filter pass band.
摘要翻译：一对环形卷绕的芯通过通过环形中心的管状绝缘构件保持大致平行的垂直隔开的关系。管状构件将绕组与通过管并联在环形绕组外部的耦合回路隔离。一个绕组是隔离电路的主要部分，将信号源通过FET器件连接到地，而另一个绕组是次级绕组，其也通过FET连接到地，并且其通过低通滤波器。 FET器件以高于信号频率和滤波器通带的频率同步脉冲。

67. 发明授权

US4331161A Patient sensor continuity detector 失效
标题翻译：患者传感器连续性检测器
公开(公告)号：US4331161A
公开(公告)日：1982-05-25
申请号：US45562
申请日：1979-06-04
申请人： Anilbhai S. Patel
发明人： Anilbhai S. Patel
IPC分类号： A61B5/00 , A61B5/0424 , A61F7/00 , A61F7/02 , A61G12/00
CPC分类号： A61F7/007 , A61B5/01 , A61B5/0424 , A61B5/6843 , A61G12/00 , A61F2007/0001 , A61F2007/0086 , A61G2203/46 , A61G2203/70
摘要： A device detects a discontinuity in the communication of a sensor with a patient by detecting separation of the sensor from the patient. An alarm responds to the detected separation of the sensor from the patient to signal the discontinuity in the sensor operation. The device is particularly useful with a patient warming device which is responsive to the patient's temperature as sensed by the sensor for controlling the heat applied to the patient.
摘要翻译：设备通过检测传感器与患者的分离来检测与患者的传感器的通信中的不连续性。警报响应于检测到的传感器与患者的分离，以指示传感器操作中的不连续性。该装置对于患者加温装置特别有用，该装置响应于由传感器感测的患者的温度，以控制施加到患者的热量。

68. 发明授权

US4294263A System for detecting probe dislodgement 失效
标题翻译：用于检测探针移位的系统
公开(公告)号：US4294263A
公开(公告)日：1981-10-13
申请号：US75253
申请日：1979-09-13
申请人： Benjamin L. Hochman
发明人： Benjamin L. Hochman
IPC分类号： A61B5/01 , A61B5/00 , A61B5/0424 , A61B18/16 , A61M5/168 , G01D5/26 , G01K7/00 , G01K13/00
CPC分类号： A61B5/01 , A61B18/16 , A61B5/0059 , A61B5/0424 , A61B5/6843 , A61M5/16831 , G01D5/268 , G01K13/002 , A61G2203/46 , Y10S200/36
摘要： A probe having a contact surface adapted to be placed on a body surface to monitor or control a body function. When the probe is dislodged from the body, an increased radiation level impinging on the contact surface is sensed and an indication of probe dislodgement is provided.
摘要翻译：具有适于放置在身体表面上的接触表面以用于监测或控制身体功能的探针。当探针从身体移出时，感测到暴露于接触表面上的增加的辐射水平并提供探针移位的指示。

69. 再颁专利

USRE30502E Open lead testing system for EEG 失效
标题翻译：开放式脑电检测系统
公开(公告)号：USRE30502E
公开(公告)日：1981-02-03
申请号：US709466
申请日：1976-08-16
申请人： Cecil C. Lencioni, Jr.
发明人： Cecil C. Lencioni, Jr.
IPC分类号： A61B5/0424 , G01R31/02
CPC分类号： G01R31/026 , A61B5/0424
摘要： A system for continuous monitoring for open circuits in multiple lead EEG systems during patient testing. Means are provided for repetitively applying a low current signal, having a distinctive waveform and frequency, to each electrode of the system. In the event an electrode is detached from the patient's scalp or otherwise open, the distinctive signal is apparent in the recorded output. Otherwise the distinctive signal is of such low magnitude that it is below the signal-to-noise ratio of the EEG amplifier. In systems including multiple leads, the test signal is successively applied to each electrode in the system in a time-controlled sequence. In one preferred embodiment a distinctive signal is used comprising a four pulse burst of 25 Hz frequency.

70. 发明授权

US4188956A Method for the analysis, display and classification of multivariate indices of brain function--a functional electrophysiological brain scan 失效
标题翻译：脑功能多变量指数分析，显示和分类方法 - 功能性电生理脑扫描
公开(公告)号：US4188956A
公开(公告)日：1980-02-19
申请号：US918730
申请日：1978-06-26
申请人： E. Roy John
发明人： E. Roy John
IPC分类号： A61B5/0424 , A61B5/0478 , A61B5/0484 , A61B5/04
CPC分类号： A61B5/7264 , A61B5/0424 , A61B5/0478 , A61B5/0484 , A61B5/7232
摘要： A method in electroencephalography (EEG) for the display of neurometric test data in which electrical activity generated by the brain either spontaneously or in response to specified challenges or conditions is detected at specified locations on the head surface of the subject by a plurality of electrodes. Features extracted from the spontaneous or evoked brain waves are quantified according to specified neurometric indices and categorized, using the mean values and standard deviations of control groups, according to their relative probability in a population of normal healthy people. Multivariate methods such as multiple analysis of variance or stepwise discriminate analysis can be used to identify independent features particularly useful for diagnosis. The values of such features can be used to construct a multivariate vector for each individual patient. If the length of this vector for data from a specified electrode placement is above the norm by a predetermined amount, for example, two standard errors, a plus sign is plotted at the corresponding position in a head diagram. If it is below the norm, for example, by more than two standard deviations (p
摘要翻译：用于显示神经测试数据的脑电图方法（EEG），其中通过多个电极在受试者的头部表面上的指定位置处检测由大脑自发产生或响应于特定挑战或条件的电活动。从自发或诱发的脑波中提取的特征根据指定的神经测量指标进行量化，并根据其在正常健康人群中的相对概率使用对照组的平均值和标准偏差进行分类。可以使用多变量方法（如多重方差分析或逐步鉴别分析）来识别对诊断特别有用的独立特征。这些特征的值可用于为每个单独的患者构建多变量载体。如果用于来自指定电极放置的数据的该向量的长度高于标准预定量，例如两个标准误差，则在头部图中的相应位置处绘制加号。如果低于规范，例如，超过两个标准偏差（p <0.01），头部图上绘制一个减号。

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