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61. 发明授权

US09232992B2 Multi-layered medical device for treating a target site and associated method 有权
标题翻译：用于治疗目标部位的多层医疗装置及相关方法
公开(公告)号：US09232992B2
公开(公告)日：2016-01-12
申请号：US12179157
申请日：2008-07-24
申请人： Matthew C. Heidner , Daniel O. Adams
发明人： Matthew C. Heidner , Daniel O. Adams
IPC分类号： A61F2/06 , A61B17/12 , A61F2/24 , A61B17/00 , A61F2/07
CPC分类号： A61F2/06 , A61B17/12036 , A61B17/12109 , A61B17/12118 , A61B17/12172 , A61B17/12177 , A61B2017/00526 , A61B2017/00592 , A61B2017/00606 , A61B2017/00623 , A61B2017/00867 , A61F2/07 , A61F2/2493 , A61F2002/068
摘要： Embodiments of the present invention provide medical devices and methods for treating a target site within the body, such as for treating vascular abnormalities. For example, one embodiment provides a stent graft including an occlusive material having a preset, overlapping configuration comprising at least three inverted overlapping layers that are folded over one another. The at least three inverted overlapping layers are configured to be separated and disposed within a catheter in a non-overlapping configuration and return to the preset, overlapping configuration when deployed from the catheter.
摘要翻译：本发明的实施方案提供用于治疗体内靶点的医疗装置和方法，例如用于治疗血管异常。例如，一个实施例提供一种支架移植物，其包括具有预设的重叠构型的封闭材料，所述重叠配置包括彼此折叠的至少三个倒置的重叠层。所述至少三个倒置的重叠层被配置为以不重叠的构造分离并设置在导管内，并且当从导管展开时返回到预设的重叠构型。

62. 发明授权

US09179920B2 Occlusion device and associated deployment method 有权
标题翻译：闭塞装置及相关部署方法
公开(公告)号：US09179920B2
公开(公告)日：2015-11-10
申请号：US14282121
申请日：2014-05-20
申请人： AGA Medical Corporation
发明人： Brooke Ren
IPC分类号： A61B17/12
CPC分类号： A61B17/12122 , A61B17/12172
摘要： An occlusion device for occluding a cavity defined by a body is provided, and includes first and second laterally-expandable portions each formed of a woven tubular fabric and having opposed proximal and distal ends. The first portion is insertable into the cavity so as to be substantially disposed therein upon lateral expansion thereof. A connective element tethers the distal end of the first portion and the second portion, and is cooperable therewith to form a collapsible assembly extending along an insertion axis. Retention members, operably engaged with each of the first and second portions and spaced apart about a laterally outward surface thereof, are adapted to engage the body, after insertion of the collapsed assembly, second portion-first, into the cavity, and subsequent lateral expansion of the first and second portions, so as to retain the assembly substantially within the cavity. An associated deployment method is also provided.
摘要翻译：提供一种用于封闭由主体限定的空腔的闭塞装置，并且包括第一和第二横向可膨胀部分，每个由编织的管状织物形成并具有相对的近端和远端。第一部分可插入空腔中，以便在其侧向膨胀时基本上设置在其中。连接元件系固第一部分和第二部分的远端，并且与其配合以形成沿着插入轴线延伸的可折叠组件。与第一部分和第二部分中的每一个可操作地接合并且围绕其横向向外表面间隔开的保持构件适于在将塌缩组件插入第二部分之后接合主体，并且随后的横向膨胀的第一和第二部分，以便将组件基本上保持在空腔内。还提供了相关的部署方法。

63. 发明授权

US09113890B2 Devices and methods for occluding vascular abnormalities 有权
标题翻译：用于阻塞血管异常的装置和方法
公开(公告)号：US09113890B2
公开(公告)日：2015-08-25
申请号：US13367011
申请日：2012-02-06
申请人： Anup Dasnurkar , Jana Santer , Matthew C. Heidner
发明人： Anup Dasnurkar , Jana Santer , Matthew C. Heidner
IPC分类号： A61M29/00 , A61B17/12 , A61B17/00
CPC分类号： A61B17/12113 , A61B17/12172 , A61B17/12177 , A61B2017/00526 , A61B2017/00592 , A61B2017/00862 , A61B2017/00867
摘要： Medical devices are provided that include at least one layer that defines a proximal end, a distal end, and an expanded volume portion between the proximal and distal ends. The expanded volume portion defines a longitudinal axis extending between the proximal and distal ends. A first end feature including a reversible connection for attachment to a pusher member may be attached to the proximal end. The first end feature may define a first axis between its opposing ends. Similarly, a second end feature defining a second axis between its opposing ends may be located at the distal end. In the contracted state (e.g., when constrained within a delivery catheter), the first axis and the second axis may be aligned with the longitudinal axis, and in the expanded state (e.g., when deployed), the first axis and/or the second axis may be angled with respect to the longitudinal axis.
摘要翻译：提供了医疗装置，其包括限定近端，远端和近端和远端之间的扩张体积部分的至少一个层。膨胀的体积部分限定在近端和远端之间延伸的纵向轴线。包括用于附接到推动器构件的可逆连接的第一端部特征可以附接到近端。第一端部特征可以在其相对端部之间限定第一轴线。类似地，在其相对的端部之间限定第二轴线的第二端部特征可以位于远端。在收缩状态（例如，当限制在输送导管内时），第一轴线和第二轴线可以与纵向轴线对准，并且在展开状态（例如，当展开时），第一轴线和/或第二轴线轴线可以相对于纵向轴线成角度。

64. 发明申请

US20140288591A1 MULTI-LAYER BRAIDED STRUCTURES FOR OCCLUDING VASCULAR DEFECTS 有权
标题翻译：用于阻塞血管缺损的多层布线结构
公开(公告)号：US20140288591A1
公开(公告)日：2014-09-25
申请号：US14282134
申请日：2014-05-20
申请人： AGA Medical Corporation
发明人： Kurt Amplatz , Matt Glimsdale , Jana Santer , Derek Wise , John C. Oslund , Kent Anderson , Daniel O. Adams
IPC分类号： A61B17/12 , A61B17/00
CPC分类号： A61B17/0057 , A61B17/12031 , A61B17/12109 , A61B17/12122 , A61B17/12159 , A61B17/12163 , A61B17/12172 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2017/00632 , A61B2017/00867 , A61B2017/12127 , A61F2/24 , A61F2250/0069
摘要： A collapsible medical device and associated methods of occluding an abnormal opening in, for example, a body organ, wherein the medical device is shaped from plural layers of a heat-treatable metal fabric. Each of the fabric layers is formed from a plurality of metal strands and the assembly is heat-treated within a mold in order to substantially set a desired shape of the device. By incorporating plural layers in the thus-formed medical device, the ability of the device to rapidly occlude an abnormal opening in a body organ is significantly improved.
摘要翻译：一种可折叠的医疗装置和在例如身体器官中闭塞异常开口的相关方法，其中所述医疗装置由多层可热处理的金属织物成形。每个织物层由多个金属线形成，并且该组件在模具内进行热处理，以便基本上设置该装置的期望形状。通过在如此形成的医疗装置中并入多层，显着提高了装置快速闭塞体内器官的异常开口的能力。

65. 发明申请

US20140257361A1 MEDICAL DEVICE FOR TREATING A TARGET SITE 审中-公开
标题翻译：用于治疗目标网站的医疗设备
公开(公告)号：US20140257361A1
公开(公告)日：2014-09-11
申请号：US13791337
申请日：2013-03-08
申请人： AGA MEDICAL CORPORATION
发明人： Darren Todd Prom
IPC分类号： A61B17/12
CPC分类号： A61B17/12022 , A61B17/12031 , A61B17/12109 , A61B17/12172 , A61B17/12177 , A61B2017/00477 , A61B2017/12095
摘要： Embodiments of the present disclosure are directed to medical devices, methods, and systems for delivering a medical device to a target site. In one embodiment, a medical device includes a proximal lobe and a distal lobe, at least one of the proximal lobe or the distal lobe configured to receive a delivery device therethrough. The medical device also includes a central engagement member disposed between the proximal lobe and the distal lobe, the central engagement member configured to be engaged by a delivery device for facilitating deployment of the proximal and distal lobes at the target site.
摘要翻译：本公开的实施例涉及用于将医疗装置递送到目标部位的医疗装置，方法和系统。在一个实施例中，医疗装置包括近侧凸耳和远端叶片，所述近侧凸耳或远侧凸起中的至少一个构造成接收穿过其中的输送装置。医疗装置还包括设置在近端瓣和远端叶之间的中心接合构件，中心接合构件构造成由输送装置接合，以便于近端和远端瓣在目标部位的展开。

66. 发明申请

US20140257357A1 OCCLUSION DEVICE AND ASSOCIATED DEPLOYMENT METHOD 有权
标题翻译： OCCLUSION设备和相关部署方法
公开(公告)号：US20140257357A1
公开(公告)日：2014-09-11
申请号：US14282121
申请日：2014-05-20
申请人： AGA Medical Corporation
发明人： Brooke Ren
IPC分类号： A61B17/12
CPC分类号： A61B17/12122 , A61B17/12172
摘要： An occlusion device for occluding a cavity defined by a body is provided, and includes first and second laterally-expandable portions each formed of a woven tubular fabric and having opposed proximal and distal ends. The first portion is insertable into the cavity so as to be substantially disposed therein upon lateral expansion thereof. A connective element tethers the distal end of the first portion and the second portion, and is cooperable therewith to form a collapsible assembly extending along an insertion axis. Retention members, operably engaged with each of the first and second portions and spaced apart about a laterally outward surface thereof, are adapted to engage the body, after insertion of the collapsed assembly, second portion-first, into the cavity, and subsequent lateral expansion of the first and second portions, so as to retain the assembly substantially within the cavity. An associated deployment method is also provided.
摘要翻译：提供一种用于封闭由主体限定的空腔的闭塞装置，并且包括第一和第二横向可膨胀部分，每个由编织的管状织物形成并具有相对的近端和远端。第一部分可插入空腔中，以便在其侧向膨胀时基本上设置在其中。连接元件系固第一部分和第二部分的远端，并且与其配合以形成沿着插入轴线延伸的可折叠组件。与第一和第二部分中的每一个可操作地接合并且围绕其横向向外的表面间隔开的保持构件适于在将塌缩的组件插入第二部分之后接合主体，并且随后的横向膨胀的第一和第二部分，以便将组件基本上保持在空腔内。还提供了相关的部署方法。

67. 发明申请

US20140249568A1 EMBOLIC PROTECTION PASS THROUGH TUBE 有权
标题翻译：通过管子进行刺激保护
公开(公告)号：US20140249568A1
公开(公告)日：2014-09-04
申请号：US13782755
申请日：2013-03-01
申请人： AGA MEDICAL CORPORATION
发明人： Daniel Adams , Mathias Charles Glimsdale , Brian Joseph Perszyk , Chris Quinn , Brooke Ren
IPC分类号： A61F2/01
CPC分类号： A61F2/013 , A61F2002/018 , A61F2230/0006 , A61F2230/0069 , A61F2230/008
摘要： An embolic protection device includes an outer surface that is configured to form a substantially sealed relationship with a body lumen such that emboli are deflected and/or captured by the outer surface before such emboli can travel to other parts of the body. An inner surface of the embolic protection device includes a longitudinally extending lumen through which instrumentation may be inserted, facilitating passage of such instrumentation through the body lumen while minimizing risk to the patient from emboli.
摘要翻译：栓塞保护装置包括外表面，其被配置为与体腔形成基本密封的关系，使得在这种栓塞可以行进到身体的其他部分之前，栓塞被外表面偏转和/或捕获。栓塞保护装置的内表面包括纵向延伸的内腔，通过该内窥镜，可以插入仪器，便于将这种仪器通过体腔，同时使患者从栓塞的风险最小化。

68. 发明申请

US20140249565A1 EMBOLIC PROTECTION DEVICE 有权
标题翻译：嵌入式保护装置
公开(公告)号：US20140249565A1
公开(公告)日：2014-09-04
申请号：US13782657
申请日：2013-03-01
申请人： AGA MEDICAL CORPORATION
发明人： Robert M. Laine
IPC分类号： A61F2/01
CPC分类号： A61F2/013 , A61F2002/016 , A61F2230/0067 , A61F2230/008 , A61F2250/0063
摘要： Embolic protection devices useful for filtering emboli during interventional cardiac, vascular, or other procedures are described. The device can include first and second expandable mesh filters having open and closed ends. The first filter is attached to a catheter at its closed end. The second filter is attached to a steerable guide wire at its closed end. The second filter includes a cinching wire circumferentially attached to the filter. The filters are deployed in separate vessels, such as the brachiocephalic artery and the left common carotid artery. A procedure is performed, and the filters trap any emboli travelling through the path of the filters. At the end of the procedure, the second filter is closed using the cinching wire, and retracted into the first filter. Both the first and second filters are collapsed into a sheath and removed from the body with along with any emboli trapped in the filters.
摘要翻译：描述了在介入心脏，血管或其他手术过程中用于过滤栓塞的栓塞保护装置。该装置可以包括具有开放和封闭端的第一和第二可膨胀网状过滤器。第一个过滤器在其封闭端连接到导管。第二个过滤器在其封闭端连接到可导向的导丝。第二过滤器包括周向地附接到过滤器的收紧线。过滤器部署在单独的容器中，例如头臂动脉和左颈总动脉。执行一个过程，并且过滤器捕获穿过过滤器路径的任何栓子。在程序结束时，使用收紧线将第二过滤器关闭，并缩回到第一过滤器中。第一和第二过滤器都被折叠成护套并且与被捕获在过滤器中的任何栓塞一起从身体移除。

69. 发明授权

US08758389B2 Devices and methods for occluding abnormal openings in a patient's vasculature 有权
标题翻译：用于阻塞病人脉管系统异常开口的装置和方法
公开(公告)号：US08758389B2
公开(公告)日：2014-06-24
申请号：US13300322
申请日：2011-11-18
申请人： Mathias C. Glimsdale
发明人： Mathias C. Glimsdale
IPC分类号： A61M29/00
CPC分类号： A61B17/0057 , A61B17/12109 , A61B17/12122 , A61B17/12172 , A61B17/12177 , A61B2017/00526 , A61B2017/00579 , A61B2017/00592 , A61B2017/00597 , A61B2017/00606 , A61B2017/00623 , A61B2017/00867 , A61B2017/12095
摘要： A medical device is provided in which one or both ends of the device encourage the formation of tissue across substantially the entire area of the respective end that is exposed to the blood flow for reducing the risk of a thrombotic embolism. The medical device includes a tubular structure having at least one expanded volume portion and a tapered transition portion. The tubular structure may be made through the braiding of a number of strands, and a first end feature may be used to secure the proximal strand ends. The proximal strand ends may be secured via the proximal end of the first end feature, such that the tapered transition portion is formed over the circumferential surface of the first end feature, and only a proximal end surface (or a portion of the proximal end surface) of the first end feature is exposed to the path of flowing blood.
摘要翻译：提供了一种医疗装置，其中装置的一端或两端促使组织穿过暴露于血流的相应末端的基本上整个区域，以减少血栓栓塞的风险。医疗装置包括具有至少一个膨胀体积部分和锥形过渡部分的管状结构。管状结构可以通过编织多个股线制成，并且可以使用第一端部特征来固定近端股末端。近端股端可以经由第一端部特征的近端固定，使得锥形过渡部分形成在第一端部特征的圆周表面上，并且仅仅近端表面（或近端表面的一部分）的第一端部特征暴露于流动的血液的路径。

70. 发明申请

US20140135734A1 DEVICES AND METHODS FOR DELIVERING VASCULAR IMPLANTS 有权
标题翻译：用于输送血管植入物的装置和方法
公开(公告)号：US20140135734A1
公开(公告)日：2014-05-15
申请号：US13771245
申请日：2013-02-20
申请人： AGA MEDICAL CORPORATION
发明人： Gregory James Dakin , Darren Todd Prom , Anup Dasnurkar
IPC分类号： A61M25/00
CPC分类号： A61M25/0082 , A61B17/12022 , A61B2017/00526 , A61B2017/00623 , A61B2017/12054 , Y10T29/49826
摘要： Embodiments of the present disclosure are directed to delivery devices, methods, and systems for delivering an implant to a target site. In one embodiment, a delivery device includes a core member defining a proximal end and a distal end and an outer winding defining a proximal end and a distal end, wherein the outer winding surrounds and is coupled to the core member. The outer winding extends at least partially between the proximal end of the core member and the distal end of the core member, and the outer winding is configured for displacement within a delivery catheter. The delivery device further includes a coupling member at the distal end of the core member configured to releasably attach to an implant.
摘要翻译：本公开的实施例涉及用于将植入物递送到目标部位的递送装置，方法和系统。在一个实施例中，输送装置包括限定近端和远端的芯构件和限定近端和远端的外绕组，其中外绕组围绕并联接到芯构件。外绕组至少部分地延伸在芯构件的近端和芯构件的远端之间，并且外绕组构造成用于在输送导管内移位。输送装置还包括在芯构件的远端处的构造成可释放地附接到植入物的联接构件。

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