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    • 61. 发明授权
    • Image processing device, image processing method, and program
    • 图像处理装置,图像处理方法和程序
    • US08948506B2
    • 2015-02-03
    • US13581784
    • 2011-01-05
    • Yasushi SaitoIsao Hirota
    • Yasushi SaitoIsao Hirota
    • G06K9/00G06T5/00H04N9/04G06K9/46
    • G06T5/007G06K9/4671G06T3/4015H04N9/045H04N2209/046
    • A device and method for generating RGB arrangement data from an imaging signal by a photograph imaging device having an RGBW arrangement are provided. An edge detection unit analyzes an output signal in the RGBW arrangement from the imaging device, and thus obtains edge information corresponding to each pixel, and a texture detection unit generates texture information. Furthermore, a parameter calculation unit performs an interpolation process of converting an application pixel position according to the edge direction corresponding to a conversion pixel. A blend process unit inputs a parameter which the parameter calculation unit generates, edge information and texture information, and determines a conversion pixel value by performing a blend process by changing a blend ratio of the parameter which the parameter calculation unit calculates, according to the edge information corresponding to the conversion pixel and the texture information.
    • 提供了一种通过具有RGBW布置的照相成像装置从成像信号产生RGB排列数据的装置和方法。 边缘检测单元从成像装置分析RGBW布置中的输出信号,从而获得与每个像素对应的边缘信息,纹理检测单元生成纹理信息。 此外,参数计算单元执行根据与转换像素对应的边缘方向转换应用像素位置的内插处理。 混合处理单元输入参数计算单元生成的参数,边缘信息和纹理信息,并且通过根据边缘改变参数计算单元计算的参数的混合比来执行混合处理来确定转换像素值 对应于转换像素和纹理信息的信息。
    • 62. 发明申请
    • IMAGE PROCESSING DEVICE, IMAGE PROCESSING METHOD, AND PROGRAM
    • 图像处理设备,图像处理方法和程序
    • US20130216130A1
    • 2013-08-22
    • US13581784
    • 2011-01-05
    • Yasushi SaitoIsao Hirota
    • Yasushi SaitoIsao Hirota
    • G06T5/00G06K9/46
    • G06T5/007G06K9/4671G06T3/4015H04N9/045H04N2209/046
    • A device and method for generating RGB arrangement data from an imaging signal by a photograph imaging device having an RGBW arrangement are provided. An edge detection unit analyzes an output signal in the RGBW arrangement from the imaging device, and thus obtains edge information corresponding to each pixel, and a texture detection unit generates texture information. Furthermore, a parameter calculation unit performs an interpolation process of converting an application pixel position according to the edge direction corresponding to a conversion pixel. A blend process unit inputs a parameter which the parameter calculation unit generates, edge information and texture information, and determines a conversion pixel value by performing a blend process by changing a blend ratio of the parameter which the parameter calculation unit calculates, according to the edge information corresponding to the conversion pixel and the texture information.
    • 提供了一种通过具有RGBW布置的照相成像装置从成像信号产生RGB排列数据的装置和方法。 边缘检测单元从成像装置分析RGBW布置中的输出信号,从而获得与每个像素对应的边缘信息,纹理检测单元生成纹理信息。 此外,参数计算单元执行根据与转换像素对应的边缘方向转换应用像素位置的内插处理。 混合处理单元输入参数计算单元生成的参数,边缘信息和纹理信息,并且通过根据边缘改变参数计算单元计算的参数的混合比来执行混合处理来确定转换像素值 对应于转换像素和纹理信息的信息。
    • 64. 发明申请
    • IMAGE PROCESSING APPARATUS AND IMAGE PROCESSING METHOD, AND PROGRAM
    • 图像处理设备和图像处理方法及程序
    • US20120257821A1
    • 2012-10-11
    • US13132044
    • 2010-08-19
    • Yasushi SaitoIsao Hirota
    • Yasushi SaitoIsao Hirota
    • G06K9/00
    • H04N9/045G06T3/4015H04N1/4092
    • To provide an apparatus that generates an RGB pattern data from an image pickup signal by an image pickup element having an RGBW pattern and a method. An edge detection unit analyzes an output signal of the image pickup signal of the RGBW pattern to obtain edge information corresponding to the respective pixels, and a texture detection unit generates texture information. Furthermore, a parameter calculation unit executes an interpolation processing in which an applied pixel position is changed in accordance with an edge direction of a transform target pixel to generate parameters equivalent to an interpolation pixel value. In a blend processing unit, the parameters generated by the parameter calculation unit, the edge information, and the texture information are input, in accordance with the edge information and the texture information corresponding to the transform pixel, a blend ratio of the parameters calculated by the parameter calculation unit is changed, the blend processing is executed, and a transform pixel value is decided.
    • 提供一种通过具有RGBW图案的图像拾取元件和方法从图像拾取信号生成RGB图案数据的装置。 边缘检测单元分析RGBW图案的摄像信号的输出信号,以获得与各像素对应的边缘信息,并且纹理检测单元生成纹理信息。 此外,参数计算单元执行插值处理,其中应用的像素位置根据变换目标像素的边缘方向而改变,以产生与内插像素值相等的参数。 在混合处理单元中,根据与变换像素对应的边缘信息和纹理信息,输入由参数计算单元生成的参数,边缘信息和纹理信息,由以下参数计算的参数的混合比: 改变参数计算单元,执行混合处理,并且确定变换像素值。
    • 67. 发明授权
    • Primary cultured adipocytes for gene therapy
    • 原代培养的脂肪细胞进行基因治疗
    • US07820438B2
    • 2010-10-26
    • US10518472
    • 2003-06-18
    • Masashi ItoYasushi Saito
    • Masashi ItoYasushi Saito
    • C12N5/00C12N5/10A61K48/00
    • C12N5/0653A61K35/12C12N2510/00C12N2510/02
    • The present invention relates to primary cultured adipocytes for gene therapy, where the adipocytes stably maintain a foreign gene encoding a protein that is secreted outside of cells. This invention provides cells suitable for gene therapy, which can replace bone marrow cells and liver cells used for conventional ex vivo gene therapy. The present invention established methods for transferring foreign genes into primary cultured adipocytes, which are suitable for ex vivo gene therapy; can be easily collected and implanted; and can be removed after implantation. Specifically, the present invention established these methods that use retroviral vectors. The present invention also established primary cultured adipocytes for gene therapy, where the adipocytes stably maintain a foreign gene encoding a protein that is secreted outside of cells.
    • 本发明涉及用于基因治疗的原代培养的脂肪细胞,其中脂肪细胞稳定地维持编码在细胞外分泌的蛋白质的外源基因。 本发明提供适用于基因治疗的细胞,其可代替用于常规体外基因治疗的骨髓细胞和肝细胞。 本发明建立了将外源基因转移到适合离体基因治疗的原代培养脂肪细胞中的方法; 可以轻松收集和植入; 并且可以在植入后去除。 具体地,本发明建立了使用逆转录病毒载体的这些方法。 本发明还建立了用于基因治疗的原代培养的脂肪细胞,其中脂肪细胞稳定地保持编码在细胞外分泌的蛋白质的外源基因。
    • 69. 发明申请
    • PRIMARY CULTURED ADIPOCYTES FOR GENE THERAPY
    • 用于基因治疗的主要文化ADIPOCYY
    • US20090010901A1
    • 2009-01-08
    • US12175186
    • 2008-07-17
    • Masashi ItoYasushi Saito
    • Masashi ItoYasushi Saito
    • A61K48/00A61K35/12
    • C12N5/0653A61K35/12C12N2510/00C12N2510/02
    • The present invention relates to primary cultured adipocytes for gene therapy, where the adipocytes stably maintain a foreign gene encoding a protein that is secreted outside of cells. This invention provides cells suitable for gene therapy, which can replace bone marrow cells and liver cells used for conventional ex vivo gene therapy. The present invention established methods for transferring foreign genes into primary cultured adipocytes, which are suitable for ex vivo gene therapy; can be easily collected and implanted; and can be removed after implantation. Specifically, the present invention established these methods that use retroviral vectors. The present invention also established primary cultured adipocytes for gene therapy, where the adipocytes stably maintain a foreign gene encoding a protein that is secreted outside of cells.
    • 本发明涉及用于基因治疗的原代培养的脂肪细胞,其中脂肪细胞稳定地维持编码在细胞外分泌的蛋白质的外源基因。 本发明提供适用于基因治疗的细胞,其可代替用于常规体外基因治疗的骨髓细胞和肝细胞。 本发明建立了将外源基因转移到适合离体基因治疗的原代培养脂肪细胞中的方法; 可以轻松收集和植入; 并且可以在植入后去除。 具体地,本发明建立了使用逆转录病毒载体的这些方法。 本发明还建立了用于基因治疗的原代培养的脂肪细胞,其中脂肪细胞稳定地保持编码在细胞外分泌的蛋白质的外源基因。