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61. 发明授权

US07192708B2 Nucleic acid enzyme biosensors for ions 有权
标题翻译：用于离子的核酸酶生物传感器
公开(公告)号：US07192708B2
公开(公告)日：2007-03-20
申请号：US10702676
申请日：2003-11-06
申请人： Yi Lu , Jing Li
发明人： Yi Lu , Jing Li
IPC分类号： C12Q1/68 , C07H21/04 , C12P19/34
CPC分类号： C12Q1/25 , C12Q1/68 , G01N2333/9005 , C12Q2563/179
摘要： A method of detecting the presence of an ion includes contacting a nucleic acid enzyme with a sample suspected of containing the ion, where the enzyme contains a ribonucleotide and is dependent on the ion to produce a product from a substrate, and measuring an amount of the product produced. The ion is Pb2+, and is in the presence of other ions.
摘要翻译：检测离子的存在的方法包括将核酸酶与怀疑含有离子的样品接触，其中酶含有核糖核苷酸并且依赖于离子从底物产生产物，并测量其量产品生产。离子是Pb 2+，并且存在其它离子。

62. 发明申请

US20060089397A1 Synthetic diazonamides 有权
公开(公告)号：US20060089397A1
公开(公告)日：2006-04-27
申请号：US11264502
申请日：2005-10-31
申请人： Patrick Harran , Jing Li , Susan Jeong
发明人： Patrick Harran , Jing Li , Susan Jeong
IPC分类号： C07D491/14 , A61K31/424
CPC分类号： C07D498/22
摘要： The application discloses novel synthetic compounds, modeled after unique toxins extracted from the marine invertebrate Diazona angulata useful in the treatment abnormal cell mitosis. The application also discloses novel methods for synthesis of these compounds and methods of using these compounds.

63. 发明申请

US20050276858A1 Bifunctional-modified hydrogels 审中-公开
标题翻译：双功能改性水凝胶
公开(公告)号：US20050276858A1
公开(公告)日：2005-12-15
申请号：US11093531
申请日：2005-03-30
申请人： Weiyuan Kao , Jeffrey Phillips , Jing Li , David Lok , Rathna Gundloori
发明人： Weiyuan Kao , Jeffrey Phillips , Jing Li , David Lok , Rathna Gundloori
IPC分类号： A61K47/48 , A61L15/22 , A61L15/60 , C08G81/00 , C08L101/14 , A61K9/70 , A61K9/14
CPC分类号： C08L101/14 , A61K47/60 , A61K47/6903 , A61L15/225 , A61L15/32 , A61L15/325 , A61L15/60 , C08G81/00 , C08L89/06
摘要： Disclosed are hydrogels wherein a polymer matrix is modified to contain a bifunctional poly(alkylene glycol) molecule covalently bonded to the polymer matrix. The hydrogels can be cross-linked using, for example, glutaraldehyde. The hydrogels may also be crosslinked via an interpenetrating network of a photopolymerizable acrylates. The hydrogels may also be modified to have pharmacologically-active agents covalently bonded to the poly(alkylene glycol) molecules or entrained within the hydrogel. Living cells may also be entrained within the hydrogels.
摘要翻译：公开了水凝胶，其中将聚合物基体改性为含有共价键合到聚合物基质上的双官能聚（亚烷基二醇）分子。水凝胶可以使用例如戊二醛进行交联。水凝胶也可以通过可光聚合的丙烯酸酯的互穿网络交联。水凝胶也可以被修饰成具有共价键合到聚（亚烷基二醇）分子或夹带在水凝胶内的药理活性剂。活细胞也可能被夹带在水凝胶内。

64. 发明申请

US20050262571A1 System and method to support platform firmware as a trusted process 有权
标题翻译：支持平台固件作为受信任流程的系统和方法
公开(公告)号：US20050262571A1
公开(公告)日：2005-11-24
申请号：US10786284
申请日：2004-02-25
申请人： Vincent Zimmer , Willard Wiseman , Jing Li
发明人： Vincent Zimmer , Willard Wiseman , Jing Li
IPC分类号： G06F21/00 , H04L9/00
CPC分类号： G06F21/57
摘要： A system and method to support platform firmware as a trusted process. Measurement of a trusted portion of original firmware are measured by a core root of trust measurement (CRTM). The measurement is stored in a secure manner during pre-boot. During operating system (OS)-runtime, requests are made to access an unqualified current version of firmware corresponding to a secure execution mode. A portion of the current firmware analogous to the trusted portion is measured. The measurements of the trusted original portion and unqualified current portion are compared to verify they match. If they match, it indicates that the current portion and the trusted portion are one in the same. Thus, the current portion of firmware is trustworthy. Accordingly, the firmware may be executed as a trusted process. Embodiments employ locality to enforce the trusted process. The use of locality prevents unqualified users (i.e., software) from accessing data stored by trusted firmware.
摘要翻译：将平台固件支持为可信过程的系统和方法。原始固件的受信任部分的测量是通过信任测量（CRTM）的核心根来测量的。在预引导期间，以安全的方式存储测量。在操作系统（OS） - 运行时期间，请求访问对应于安全执行模式的不合格的当前版本的固件。测量与可信部分类似的当前固件的一部分。比较可信原始部分和不合格的当前部分的测量结果，以验证它们是否匹配。如果它们匹配，则表示当前部分和可信部分是相同的。因此，固件的当前部分是值得信赖的。因此，固件可以作为可信过程来执行。实施例采用本地来强制可信过程。使用本地防止不合格用户（即，软件）访问由可信固件存储的数据。

65. 发明申请

US20050203085A1 Rifamycin C-11 oxime cyclo derivatives effective against drug-resistant microbes 有权
标题翻译：对抗耐药微生物有效的利福霉素C-11肟环衍生物
公开(公告)号：US20050203085A1
公开(公告)日：2005-09-15
申请号：US11076173
申请日：2005-03-09
申请人： Jing Li , Zhenkun Ma
发明人： Jing Li , Zhenkun Ma
IPC分类号： A61K31/5383 , A61K31/5415
CPC分类号： C07D498/18
摘要： The current invention relates to a series of rifamycin derivatives having antimicrobial activities, including activities against drug-resistant microorganisms, specifically, the 3,4-cyclo-rifamycin derivatives having an oxime group at the C-11 position.
摘要翻译：本发明涉及一系列具有抗菌活性的利福霉素衍生物，包括抗药性微生物的活性，具体地说，具有C-11位上肟基的3,4-环 - 利福霉素衍生物。

66. 发明申请

US20050118624A1 Fluorescent probes for ribosomes and method of use 审中-公开
标题翻译：核糖体荧光探针及其使用方法
公开(公告)号：US20050118624A1
公开(公告)日：2005-06-02
申请号：US10954996
申请日：2004-09-30
申请人： Zhenkun Ma , Jing Li , In Kim , Yafei Jin , Anthony Lynch , Eric Roche , Doug Beeman
发明人： Zhenkun Ma , Jing Li , In Kim , Yafei Jin , Anthony Lynch , Eric Roche , Doug Beeman
IPC分类号： C07H17/08 , C07H21/04 , C09B11/08 , C09B11/24 , C09B23/01 , C12Q1/68 , G01N33/533 , G01N33/58
CPC分类号： C09B11/08 , C09B11/24 , C09B23/0075 , G01N33/533 , G01N33/582 , G01N2500/00
摘要： Fluorescent probes that have binding affinity to ribosomes. The fluorescent probes are useful tools for identifying small molecules that bind to the 50S or 30S subunits of the bacterial and other ribosomes and serve as novel ribosome inhibitors. These probes are also useful for determining the interactions between a specific ligand and the ribosome.
摘要翻译：对核糖体具有结合亲和力的荧光探针。荧光探针是用于鉴定结合细菌和其他核糖体的50S或30S亚基的小分子并用作新的核糖体抑制剂的有用工具。这些探针也可用于确定特异性配体和核糖体之间的相互作用。

67. 发明授权

US06884422B1 Freeze-dried hepatitis A attenuated live vaccine and its stabilizer 有权
标题翻译：冷冻干燥的甲型肝炎减毒活疫苗及其稳定剂
公开(公告)号：US06884422B1
公开(公告)日：2005-04-26
申请号：US09807783
申请日：1999-10-10
申请人： Jingye Liu , Pengfu Wang , Guangpu Li , Baosheng Xie , Zongming Song , Shuyan Li , Jing Liu , Ying Yu , Xizhen Guangpu Zhang , Ben Liang , Lingjiu Liu , Wei Wang , Ling Zhang , Yong Xue , Jing Li , Yuhong Li , Hui Lin , Zongju Wan
发明人： Jingye Liu , Pengfu Wang , Guangpu Li , Baosheng Xie , Zongming Song , Shuyan Li , Jing Liu , Ying Yu , Xizhen Guangpu Zhang , Ben Liang , Lingjiu Liu , Wei Wang , Ling Zhang , Yong Xue , Jing Li , Yuhong Li , Hui Lin , Zongju Wan
IPC分类号： A61K9/19 , A61K39/29 , A61P31/12 , A61K39/245 , C12N13/00 , C12N7/00
CPC分类号： A61K9/19 , A61K39/12 , A61K39/29 , A61K2039/5254 , C12N2760/18434 , C12N2770/32434 , Y02A50/464
摘要： The present invention relates to hepatitis A vaccine, especially to a lyophilized attenuated hepatitis A vaccine which can be stored at ambient temperature for extended periods of time, and to a method for producing the same. The present invention further relates to a stabilizer for lyophilized live vaccine and its use in improving thermostability of lyophilized live vaccine during lyophilization processing and storage period after lyophilization.
摘要翻译：本发明涉及甲型肝炎疫苗，特别涉及可在环境温度下长时间储存的冻干减毒甲型肝炎疫苗及其制备方法。本发明还涉及一种用于冻干活疫苗的稳定剂及其在冷冻干燥处理和冷冻干燥后的保存期间用于提高冻干活疫苗的热稳定性的用途。

68. 发明授权

US06657559B1 Mouse with remote control function of infrared ray 失效
标题翻译：鼠标具有红外线遥控功能
公开(公告)号：US06657559B1
公开(公告)日：2003-12-02
申请号：US09581403
申请日：2000-07-25
申请人： Jing Li
发明人： Jing Li
IPC分类号： H03K1794
CPC分类号： G06F3/0383
摘要： A mouse with infrared remote control function comprises: an optical encode control circuit, a microprocessor circuit, a wire driver circuit of the transmitting part, an infrared modulating transmitter circuit, an infrared receiving demodulation circuit, a wire driver circuit of the receiving part, an interface switching circuit, a receiver/transmitter interface circuit and a power circuit (it can be switched off) for supplying the power circuit to the said optical encode control circuit, microprocessor circuit, infrared modulating transmitter circuit. Besides a single-purpose mouse with infrared remote control function is provided by the present invention, by using the interface switch circuit and automatic switch circuit, a dual-purpose mouse with both compatible infrared remote control function and compatible cable control function can be implemented.
摘要翻译：具有红外遥控功能的鼠标包括：光学编码控制电路，微处理器电路，发射部分的线驱动电路，红外调制发射机电路，红外接收解调电路，接收部分的线驱动电路，接口切换电路，接收器/发射器接口电路和电源电路（可以关闭），用于向所述光编码控制电路，微处理器电路，红外调制发射机电路提供电源电路。本发明提供了具有红外遥控功能的单用鼠标，通过使用接口开关电路和自动切换电路，可以实现具有兼容的红外遥控功能和兼容电缆控制功能的双用途鼠标。

69. 发明授权

US06410940B1 Micro-size LED and detector arrays for minidisplay, hyper-bright light emitting diodes, lighting, and UV detector and imaging sensor applications 有权
标题翻译：用于微型显示器，超亮度发光二极管，照明和UV检测器和成像传感器应用的微尺寸LED和检测器阵列
公开(公告)号：US06410940B1
公开(公告)日：2002-06-25
申请号：US09594960
申请日：2000-06-15
申请人： Hongxing Jiang , Jingyu Lin , Sixuan Jin , Jing Li
发明人： Hongxing Jiang , Jingyu Lin , Sixuan Jin , Jing Li
IPC分类号： H01L2715
CPC分类号： B82Y20/00 , H01L27/14601 , H01L27/156 , H01L31/035236 , H01L31/12 , H01L33/08
摘要： A micro-size LED-like optical element has an n-contact, a p-contact, and an optical active structure connected between the n-contact and the p-contact for generating light when forward biased and for detecting light when reverse biased. The optical active structure has a diameter of about 20 &mgr;m or smaller. When the the optical active structure is forward biased, it forms a micro-size LED (&mgr;LED). When the optical active structure is reverse biased, it forms a micro-size detector (&mgr;detector). An array of the micro-size optical active structures may be used as a minidisplay, a detector, or a sensor (when each structure is separately wired), or as a hyperbright LED (when the structures are wired to turn on and off simultaneously). Alternatively, a hyperbright LED may be obtained by forming a plurality of micro-size holes extending into an LED wafer.
摘要翻译：微尺寸LED状光学元件具有n接触，p接触和连接在n接触和p接触之间的光学有源结构，用于当正向偏置时产生光并且用于当反向偏置时检测光。光学活性结构的直径约为20μm或更小。当光学有源结构正向偏置时，它形成微尺寸LED（muLED）。当光学有源结构被反向偏置时，它形成微尺寸检测器（泥浆仪）。微尺寸光学活性结构的阵列可以用作微型显示器，检测器或传感器（当每个结构单独布线时），或者作为超光LED（当结构被布线以同时打开和关闭时）。或者，可以通过形成延伸到LED晶片中的多个微尺寸孔来获得超光LED。

70. 发明授权

US6127573A Oxidaton of primary alcohols to carboxylic acids with a TEMPO catalyst using NaClO.sub.2 and NaClO 失效
标题翻译：使用NaClO2和NaClO，用TEMPO催化剂将伯醇氧化成羧酸
公开(公告)号：US6127573A
公开(公告)日：2000-10-03
申请号：US283936
申请日：1999-04-01
申请人： Jing Li , Zhiguo Song , David M. Tschaen , Mangzu Zhao
发明人： Jing Li , Zhiguo Song , David M. Tschaen , Mangzu Zhao
IPC分类号： C07C51/16
CPC分类号： C07C51/29 , C07C201/12 , C07C269/06 , C07D263/52
摘要： The present invention relates to a TEMPO-catalyzed oxidation of primary alcohols, RCH.sub.2 OH to corresponding carboxylic acids, RCOOH in the presence of catalytic in the presence of catalytic amount of NaClO and stoichiometric amount of NaClO.sub.2 as an oxidant. ##STR1##
摘要翻译：本发明涉及在催化量的NaClO和化学计量的NaClO 2作为氧化剂的存在下，在催化剂存在下，将伯醇，RCH 2 OH的TEMPO催化氧化成相应的羧酸RCOOH。

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