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61. 发明授权

US07841670B2 Vehicle wheel 有权
标题翻译：车轮
公开(公告)号：US07841670B2
公开(公告)日：2010-11-30
申请号：US12656383
申请日：2010-01-28
申请人： Kazuo Takeda , Tomokazu Nishikawa , Daiichiro Kawashima , Tatsuya Oba , Tetsuya Arakawa , Koji Murakami , Kenichi Sakanoshita
发明人： Kazuo Takeda , Tomokazu Nishikawa , Daiichiro Kawashima , Tatsuya Oba , Tetsuya Arakawa , Koji Murakami , Kenichi Sakanoshita
IPC分类号： B60B7/06
CPC分类号： B60B7/14 , B60B7/0053 , B60B7/04 , B60B7/06 , B60B7/063 , B60B7/066 , B60B7/08 , B60B7/18
摘要： The degree of freedom in design is increased while maintaining strength by enabling a decorative member to be disposed without thinning a wheel main body.A wheel is made up of a wheel main body 1 which is made up of a rim portion 10 and a disc portion 11 and which has a vent hole 141 in the disc portion 11 and a decorative member 2 made from a resin which is held in at least the disc portion 11 and is observed from the vent hole 141. Since the decorative member 2 is observed in the vent hole 141, the wheel main body 1 including spoke portions 14 does not have to be thinned. In addition, since the design of the decorative member is observed in cooperation with the design of the disc portion 11, the degree of freedom in design is increased.
摘要翻译：通过使装饰构件能够在不使轮主体变薄的情况下进行设置，可以提高设计自由度，同时保持强度。车轮由轮缘主体1构成，车轮主体1由轮辋部分10和盘部分11构成，并且在盘部分11中具有通气孔141，以及由树脂制成的装饰件2 至少是圆盘部分11，并且从通气孔141观察到。由于在通气孔141中观察到装饰件2，所以包括轮辐部分14的轮主体1不一定要变薄。此外，由于与盘部11的设计配合观察装饰构件的设计，因此设计的自由度增加。

62. 发明申请

US20100210591A1 BIS(TRIMETHYLSILYL)PHENYL COMPOUND OR SALT THEREOF, AND USE THEREOF 失效
标题翻译： BIS（三甲基甲硅烷基）苯基化合物或其盐，及其用途
公开(公告)号：US20100210591A1
公开(公告)日：2010-08-19
申请号：US12682097
申请日：2008-10-10
申请人： Yoshimitsu Suda , Hiromi Oshiumi , Koji Murakami
发明人： Yoshimitsu Suda , Hiromi Oshiumi , Koji Murakami
IPC分类号： A61K31/695 , C07F7/10
CPC分类号： C07F7/0812 , C07F7/081
摘要： The present invention provides a compound that exhibits an excellent antitumor effect and reduces side effects, such as skin disorders, of the existing retinoid by selectively activating on the nuclear receptor RARα, thereby possibly producing significant improvement of clinical profits. Specifically, the present invention provides a bis(trimethylsilyl)phenyl compound represented by Formula (I): wherein X is N or CH; Y is O or S; R1, R2, and R3 are the same or different and are hydrogen or lower alkyl; R4 and R5 are the same or different and are hydrogen, lower alkyl, or halogen; and a bond between a carbon atom to which R1 is attached and a carbon atom to which R2 is attached is a single bond or a double bond; or a salt thereof.
摘要翻译：本发明提供通过选择性活化核受体RARα而显示出优异的抗肿瘤效果并降低现有类视色素的副作用，例如皮肤病，从而可能显着改善临床利益。具体地说，本发明提供由式（I）表示的双（三甲基甲硅烷基）苯基化合物：其中X是N或CH; Y为O或S; R1，R2和R3相同或不同，为氢或低级烷基; R4和R5相同或不同，为氢，低级烷基或卤素; 并且R 1所连接的碳原子和R 2所连接的碳原子之间的键为单键或双键; 或其盐。

63. 发明申请

US20100093825A1 Bicycloester derivative 失效
标题翻译：双环衍生物
公开(公告)号：US20100093825A1
公开(公告)日：2010-04-15
申请号：US12654018
申请日：2009-12-08
申请人： Yasumichi Fukuda , Yoshikazu Asahina , Kohei Ohata , Kazuya Yokota , Koji Murakami , Toshiyuki Matsui
发明人： Yasumichi Fukuda , Yoshikazu Asahina , Kohei Ohata , Kazuya Yokota , Koji Murakami , Toshiyuki Matsui
IPC分类号： A61K31/40 , A61K31/4025 , A61P3/00 , A61P19/10 , A61P35/00
CPC分类号： C07D405/12 , C07D207/16 , Y02P20/55
摘要： SummaryNovel bicycloester derivatives and pharmaceutically acceptable salts thereof have high DPP-IV inhibitory activity.Solving MeansThe novel bicycloester derivatives are represented by the general formula (1): Pharmaceutically acceptable salts thereof are also included (Example: (2S,4S)-1-[[(N-(4-ethoxycarbonylbicyclo[2.2.2]oct-1-yl)amino]acetyl]-4-fluoropyrrolidine-2-carbonitrile)).
摘要翻译：发明概述新型双环衍生物及其药学上可接受的盐具有高的DPP-IV抑制活性。解决方法新型双环衍生物由通式（1）表示：其药学上可接受的盐也包括在实施例中：（2S，4S）-1 - [[（N-（4-乙氧羰基双环[2.2.2] 吡啶-1-基）氨基]乙酰基] -4-氟吡咯烷-2-腈））。

64. 发明申请

US20090124631A1 Combination Therapy 审中-公开
标题翻译：联合治疗
公开(公告)号：US20090124631A1
公开(公告)日：2009-05-14
申请号：US12209419
申请日：2008-09-12
申请人： Zuomei Li , Koji Murakami
发明人： Zuomei Li , Koji Murakami
IPC分类号： A61K31/506 , A61P35/00 , A61K31/4439 , A61K31/337 , A61K31/40 , A61K31/4468 , A61K31/496 , A61K31/427
CPC分类号： A61K45/06 , A61K31/337 , A61K31/402 , A61K31/4439 , A61K31/451 , A61K31/496 , A61K31/506 , A61K2300/00
摘要： The invention relates to the treatment of mammalian diseases manifested by abnormal cell growth and/or abnormal cell proliferation. More particularly, the invention relates to the use of combination therapies to control abnormal cell growth and/or abnormal cell proliferation. In particular, the invention relates to the use of isotype-selective inhibitors of histone deacetylases 1, 2 and/or 3 (HDACs 1-3), as well as isotype-selective inhibitors of HDAC1 and/or HDAC2, to potentiate therapeutic activity of microtubule-stabilization agents.
摘要翻译：本发明涉及由异常细胞生长和/或异常细胞增殖所表现的哺乳动物疾病的治疗。更具体地，本发明涉及组合疗法用于控制异常细胞生长和/或异常细胞增殖的用途。特别地，本发明涉及组蛋白脱乙酰酶1,2和/或3（HDAC1-3）的同种型选择性抑制剂以及HDAC1和/或HDAC2的同种型选择性抑制剂在增强治疗活性中的用途微管稳定剂。

65. 发明申请

US20080303338A1 Wheel for vehicle 有权
标题翻译：车轮
公开(公告)号：US20080303338A1
公开(公告)日：2008-12-11
申请号：US12155246
申请日：2008-05-30
申请人： Kazuo Takeda , Tatsuya Oba , Tetsuya Arakawa , Koji Murakami , Kenji Fukuda , Kazuki Yamazaki
发明人： Kazuo Takeda , Tatsuya Oba , Tetsuya Arakawa , Koji Murakami , Kenji Fukuda , Kazuki Yamazaki
IPC分类号： B60B1/00
CPC分类号： B60B7/14
摘要： A wheel for vehicle includes a wheel body, a decorated member, and a visible space. The wheel body has a rim, a hub, and a plurality of spokes connecting the hub and the rim. The decorated member is made from resin, is disposed on a surface of at least one of the spokes, and is retained to the wheel body. The visible space is disposed between the decorated member and the one of the spokes at least, exhibits a height in an axial direction of the wheel body, and is visible from an axial outer side of the wheel body.
摘要翻译：用于车辆的车轮包括轮体，装饰构件和可见空间。轮体具有轮辋，轮毂和连接轮毂和轮辋的多个辐条。装饰构件由树脂制成，设置在至少一个辐条的表面上，并被保持在轮体上。所述可视空间至少设置在所述装饰构件和所述一个所述辐条之间，在所述车轮主体的轴向方向上具有高度，并且从所述车轮主体的轴向外侧可见。

66. 发明申请

US20050217798A1 Plasma processing apparatus 审中-公开
标题翻译：等离子体处理装置
公开(公告)号：US20050217798A1
公开(公告)日：2005-10-06
申请号：US11088211
申请日：2005-03-22
申请人： Akira Sugiyama , Shuhichi Kitamura , Koji Murakami , Daisuke Takahashi , Shohzoh Yoshimoto
发明人： Akira Sugiyama , Shuhichi Kitamura , Koji Murakami , Daisuke Takahashi , Shohzoh Yoshimoto
IPC分类号： H05H1/24 , C23C16/50 , C23F1/00 , H01J37/32 , H01L21/304 , H01L21/3065
CPC分类号： H01J37/32009 , H01J37/32082 , H01J37/32532
摘要： The plasma processing apparatus includes main electrodes 5, 31 opposed to each other with a plasma processing space 15 interposed therebetween. The plasma processing apparatus further has a side electrode 6 opposed to side faces 5B-1, 5B-2 of the main electrode 5, as well as a side electrode 32 opposed to side faces 31B-1, 31B-2 of the main electrode 31. Therefore, in addition to the plasma processing space 15 between the main electrode 5 and the main electrode 31, an electric field can be formed in spaces between the side faces of the main electrodes 5, 31 and the side electrodes 6, 32, the spaces serving as predischarge areas 16-1, 16-2. By this electric field, processing gas present in the predischarge areas 16-1, 16-2 can be transformed into plasma. Electrons and excitation species of the plasma generated in these predischarge areas 16-1, 16-2 can be supplied directly to the plasma processing space 15.
摘要翻译：等离子体处理装置包括彼此相对的主电极5,31，其间插入等离子体处理空间15。等离子体处理装置还具有与主电极5的侧面5B-B-B-B-B相对的侧面电极6以及与侧面31B-1，31B-2相对的侧面电极32 主电极31.因此，除了主电极5和主电极31之间的等离子体处理空间15之外，可以在主电极5,31的侧面与侧电极6之间的空间中形成电场，32，用作预充电区域16-1,16-2的空间。通过该电场，存在于预充电区域16-1,16-2中的处理气体可以转换成等离子体。在这些预放电区域16-1,16-2中产生的等离子体的电子和激发物质可以直接供应到等离子体处理空间15。

67. 发明授权

US06730687B1 Substituted benzylthiazolidine-2, 4-dione derivatives 失效
标题翻译：取代的苄基噻唑烷-2,4-二酮衍生物
公开(公告)号：US06730687B1
公开(公告)日：2004-05-04
申请号：US10049645
申请日：2002-02-25
申请人： Hiroyuki Miyachi , Masahiro Nomura , Takahiro Tanase , Koji Murakami , Masaki Tsunoda
发明人： Hiroyuki Miyachi , Masahiro Nomura , Takahiro Tanase , Koji Murakami , Masaki Tsunoda
IPC分类号： A61K31426
CPC分类号： C07D277/34
摘要： The invention provides novel substituted benzylthiazolidine-2,4-dione derivatives that bind to receptor to activate as ligands of human peroxisome proliferator-activated receptor (PPAR) and exhibit blood glucose-decreasing action and lipid-decreasing action, and processes for preparing them. It relates to substituted benzylthiazolidine-2,4-dione derivatives represented by the general formula (1) [wherein the bond mode of A denotes —CH2CONH—, —NHCONH—, —CH2CH2CO— or —NHCOCH2—, and B denotes a lower alkyl group with carbon atoms of 1 to 4, lower alkoxy group with carbon atoms of 1 to 3, halogen atom, trifluoromethyl group, trifluoromethoxy group, phenyl group which is unsubstituted or may have substituents, phenoxy group which is unsubstituted or may have substituents or benzyloxy group which is unsubstituted or may have substituents], their medicinally acceptable salts, their hydrates and processes for preparing them.
摘要翻译：本发明提供了新的取代的苄基噻唑烷-2,4-二酮衍生物，其结合受体以作为人类过氧化物酶体增殖物激活受体（PPAR）的配体活化并显示出血糖降低作用和降脂作用，以及制备它们的方法。它涉及由通式（1）表示的取代的苄基噻唑烷-2,4-二酮衍生物[其中A的键合模式表示-CH 2 CONH-，-NHCONH-，-CH 2 CH 2 CO-或-NHCOCH 2 - ，B表示低级烷基具有1至4个碳原子的烷基，具有1至3个碳原子的低级烷氧基，卤素原子，三氟甲基，三氟甲氧基，未取代或可具有取代基的苯基，未被取代或可具有取代基的苯氧基或可具有取代基的苯氧基未取代或可具有取代基的基团]，它们的药学上可接受的盐，它们的水合物及其制备方法。

68. 发明授权

US5902138A Branch junction box 失效
标题翻译：分支接线盒
公开(公告)号：US5902138A
公开(公告)日：1999-05-11
申请号：US599953
申请日：1996-02-14
申请人： Koji Murakami
发明人： Koji Murakami
IPC分类号： H01R9/24 , H01R31/08 , H02G3/16 , H05K1/00 , H05K1/02 , H05K3/00 , H05K3/20 , H05K3/30 , H05K3/40 , H01R9/09
CPC分类号： H05K3/306 , H01R9/2466 , H05K1/0263 , H01R12/59 , H01R31/08 , H05K1/0284 , H05K1/0393 , H05K2201/0352 , H05K2201/09045 , H05K2201/091 , H05K2201/09118 , H05K2201/10272 , H05K2201/10583 , H05K2201/10651 , H05K2203/167 , H05K3/0058 , H05K3/202 , H05K3/4084
摘要： A branch junction box containing a flexible printed circuit sheet includes circuit terminals and other parts which are easily mounted. A first insulation plate is provided on one of its faces, with a plurality of printed circuit terminals vertically fixed therethrough. On its other face, the first insulation plate carries a flexible printed circuit sheet, the printed circuit of which is electrically connected to the circuit terminals. The surface of the insulating plate facing the circuit terminals may be provided with bus bar wiring patterns and corresponding bus bar terminals. These circuit terminals and bus bar terminals are branch-connected to wiring harnesses in a proper and reliable way through connectors formed in the casing of the box.
摘要翻译：包含柔性印刷电路板的分支接线盒包括电路端子和容易安装的其它部件。第一绝缘板设置在其一个面上，多个印刷电路端子垂直固定在其中。在另一面上，第一绝缘板带有柔性印刷电路板，其印刷电路电连接到电路端子。面向电路端子的绝缘板的表面可以设置有母线布线图案和相应的母线端子。这些电路端子和母线端子通过形成在盒的壳体中的连接器以适当且可靠的方式分支连接到线束。

69. 发明授权

US5750515A Cancer metastasis inhibitor 失效
标题翻译：癌转移抑制剂
公开(公告)号：US5750515A
公开(公告)日：1998-05-12
申请号：US737799
申请日：1996-11-26
申请人： Jiro Shibata , Konstanty Wierzba , Koji Murakami , Yuji Yamada , Koichi Shudo
发明人： Jiro Shibata , Konstanty Wierzba , Koji Murakami , Yuji Yamada , Koichi Shudo
IPC分类号： A61K31/192 , A61K31/196 , A61K31/695 , A61P35/04 , A61K31/19 , A61K31/20
CPC分类号： A61K31/695 , A61K31/192 , A61K31/196
摘要： The present invention relates to a cancer metastasis inhibitor comprising a benzoic acid derivative as an active ingredient represented by the formula (I) ##STR1## wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are the same or different and each represents hydrogen atom, hydroxyl group or trimethylsilyl group, or R.sub.3 and R.sub.4 are bonded to each other to form a tetramethylene group substituted with lower alkyl group, and X represents group --COCH.dbd.C(OH)--, group --NHCO-- or group --CONH--, provided that when R.sub.3 and R.sub.4 are bonded to each other to form a tetramethylene group substituted with lower alkyl group, X is group --COCH.dbd.C(OH)-- or group --CONH--, use of the benzoic acid derivative for preparing the cancer metastasis inhibitor and method of inhibiting cancer metastasis, characterized in that an effective amount of the benzoic acid derivative is administered to a mammalian animal for inhibiting metastasis of cancer. The benzoic acid derivative represented by the above formula (I) has extremely good metastasis inhibiting properties.
摘要翻译： PCT No.PCT / JP96 / 00980 Sec。 371日期1996年11月26日 102（e）1996年11月26日PCT PCT 1996年4月10日PCT公布。第WO96 / 32101号公报日期：1996年10月17日本发明涉及包含苯甲酸衍生物作为由式（I）表示的活性成分的癌症转移抑制剂，其中R1，R2，R3和R4相同或不同，各自表示氢原子，羟基或三甲基甲硅烷基，或者R 3和R 4相互键合形成被低级烷基取代的四亚甲基，X表示-COCH = C（OH） - 基团，-NHCO-或基团 -CONH-，条件是当R 3和R 4彼此键合以形成被低级烷基取代的四亚甲基时，X是基团-COCH = C（OH） - 或基团-CONH-，使用苯甲酸衍生物制备癌转移抑制剂和抑制癌转移的方法，其特征在于向哺乳动物施用有效量的苯甲酸衍生物以抑制癌转移。上述式（I）表示的苯甲酸衍生物具有极好的转移抑制性质。

70. 发明授权

US5551912A Coin conveying apparatus 失效
标题翻译：硬币输送装置
公开(公告)号：US5551912A
公开(公告)日：1996-09-03
申请号：US297509
申请日：1994-08-29
申请人： Takatoshi Takemoto , Tosikazu Chida , Noriaki Kano , Eizi Ito , Koji Murakami , Takasi Itagaki , Kozo Sekimoto , Masanori Suzuki
发明人： Takatoshi Takemoto , Tosikazu Chida , Noriaki Kano , Eizi Ito , Koji Murakami , Takasi Itagaki , Kozo Sekimoto , Masanori Suzuki
IPC分类号： B65G47/66 , G07D9/00 , G07D1/00 , B65G47/56
CPC分类号： G07D9/00 , B65G47/66 , Y10S193/01
摘要： The ending side of one coin conveying endless belt is made higher than the starting side of another adjacent coin conveying endless belt. Between the ending side of the one coin conveying belt and the starting side of the another coin conveying belt, there is provided a coin slide to let the coins, which have reached the ending side of the one coin conveying belt, slide down to the starting side of the another coin conveying belt. By using the coin slide, the transference of coins from the one coin conveying belt to the another coin conveying belt can be ensured.
摘要翻译：输送环形带的一个硬币的终端被制成高于另一个相邻硬币输送环形带的起始侧。在一个硬币输送带的结束侧和另一个硬币输送带的起始侧之间，设置有硬币滑块，以使已经到达一个硬币输送带的终止侧的硬币向下滑动到起始另一个硬币传送带的一侧。通过使用硬币滑块，可以确保硬币从一个硬币输送带转移到另一个硬币输送带。

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