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61. 发明申请

US20130231701A1 SUTURE SECURING SYSTEMS, DEVICES AND METHODS 有权
标题翻译：保护系统，设备和方法
公开(公告)号：US20130231701A1
公开(公告)日：2013-09-05
申请号：US13411320
申请日：2012-03-02
申请人： Laveille Kao Voss , Aaron M. Fortson , Douglas H. Mehl , Rizza Garcia , Wouter E. Roorda
发明人： Laveille Kao Voss , Aaron M. Fortson , Douglas H. Mehl , Rizza Garcia , Wouter E. Roorda
IPC分类号： A61B17/06
CPC分类号： A61B17/0057 , A61B17/0401 , A61B17/0467 , A61B17/0485 , A61B17/0487 , A61B17/12136 , A61B2017/00654 , A61B2017/00663 , A61B2017/0417 , A61B2017/0454 , A61B2017/0461 , A61B2017/0464 , A61B2017/06176
摘要： A suture securing system is provided for use in closing a vessel puncture site while eliminating the need for sutures to be manually tied in knots. The system may include an elongate body comprising a shaft and a barrel slidably mounted on the shaft. A knot replacement element may include an outer surface and an inner lumen configured to receive suture lengths. The knot replacement element may be at least partially positioned within the distal end of the barrel adjacent to the distal portion of the shaft and may be configured to selectively fasten the suture lengths together over the vessel repair site. The system may also include a snare configured to draw the suture lengths through the knot replacement element and at least a portion of the elongate body. A trimmer member may be configured to selectively trim the suture lengths extending from the knot replacement element.
摘要翻译：提供缝合线固定系统用于封闭血管穿刺部位，同时消除缝合线手动绑扎的需要。该系统可以包括细长主体，其包括轴和可滑动地安装在轴上的筒体。结更换元件可以包括构造成接收缝合线长度的外表面和内腔。结更换元件可以至少部分地定位在与轴的远侧部分相邻的镜筒的远端内，并且可以被配置为在血管修复位置上选择性地将缝合线长度紧固在一起。该系统还可以包括被配置为通过结更换元件和细长主体的至少一部分绘制缝合线长度的圈套。修剪器构件可以被配置为选择性地修剪从结更换元件延伸的缝合线长度。

62. 发明授权

US08517979B2 Carriers for hemostatic tract treatment 有权
标题翻译：止血道治疗载体
公开(公告)号：US08517979B2
公开(公告)日：2013-08-27
申请号：US12643612
申请日：2009-12-21
申请人： Wouter E. Roorda , Stefan Richter
发明人： Wouter E. Roorda , Stefan Richter
IPC分类号： A61M31/00
CPC分类号： A61L29/16 , A61B17/0057 , A61B17/0467 , A61B2017/00668 , A61B2017/00672 , A61B2017/00884 , A61B2090/036 , A61B2090/062 , A61B2090/0807 , A61L29/085 , A61L31/10 , A61L31/16 , A61M25/0009 , A61M25/0045 , A61M25/0097 , A61M25/04 , A61M29/00
摘要： Apparatuses and methods for administering a hemostatic agent to the tissue surrounding an opening in a body lumen are disclosed. The apparatus can include a tissue-contacting region and an optional body lumen-penetrating region. At least one hemostatic agent is included as a component of a coating over and/or a mixture with the material of at least a portion of the tissue-contacting region.
摘要翻译：公开了一种用于向身体腔中的开口周围的组织施用止血剂的装置和方法。该装置可以包括组织接触区域和任选的身体内腔穿透区域。至少一种止血剂作为涂层的组分包含在组织接触区域的至少一部分的材料上和/或混合物中。

63. 发明申请

US20130190810A1 CLOSURE DEVICE 有权
标题翻译：封闭装置
公开(公告)号：US20130190810A1
公开(公告)日：2013-07-25
申请号：US13791829
申请日：2013-03-08
申请人： Wouter E. Roorda , Kelly J. McCrystle , Ian J. Clark , Laveille K. Voss , Ni Ding
发明人： Wouter E. Roorda , Kelly J. McCrystle , Ian J. Clark , Laveille K. Voss , Ni Ding
IPC分类号： A61B17/00
CPC分类号： A61B17/0057 , A61B2017/00004 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2017/00619 , A61B2017/00623 , A61B2017/00654 , A61B2017/00659 , A61B2017/00986 , A61B2017/00991 , A61B2090/0811
摘要： A device for closing an opening in a wall of a body lumen includes a closure element with a first flange and a second flange. Both the first flange and the second flange may have a delivery cross-sectional dimension and a deployed cross-sectional dimension. The device for closing an opening further includes a first coupler element disposed on the first flange and a second coupler element disposed on the second flange, the first and second coupler elements cooperating to couple the first flange to the second flange.
摘要翻译：用于关闭体腔内的开口的装置包括具有第一凸缘和第二凸缘的闭合元件。第一凸缘和第二凸缘都可以具有输送横截面尺寸和展开的横截面尺寸。用于关闭开口的装置还包括设置在第一凸缘上的第一耦合器元件和设置在第二凸缘上的第二耦合器元件，第一和第二耦合器元件协作以将第一凸缘耦合到第二凸缘。

64. 发明申请

US20120296374A1 TISSUE EVERSION APPARATUS AND TISSUE CLOSURE DEVICE AND METHODS FOR USE THEREOF 有权
标题翻译：组织代谢装置及组织闭合装置及其使用方法
公开(公告)号：US20120296374A1
公开(公告)日：2012-11-22
申请号：US13111403
申请日：2011-05-19
申请人： John M. Ziobro , Wouter E. Roorda
发明人： John M. Ziobro , Wouter E. Roorda
IPC分类号： A61B17/00
CPC分类号： A61B17/0057 , A61B2017/0065 , A61B2017/00659 , A61B2017/00668 , A61B2017/1121
摘要： Methods and apparatuses for closure of vascular punctures or other openings in bodily tissues. The apparatuses and methods described herein are configured for everting a portion of tissue around a puncture site for wound closure on the external surface of the wound. For example, the tissue eversion apparatus may be configured for drawing up a portion of a vessel surrounding a venous or arterial puncture and orienting the inner surface of the vessel at least partially outward so that a closure element may be placed around the inverted region on the exterior surface of the vessel. In some embodiments, the devices are bioabsorbable.
摘要翻译：用于在身体组织中闭合血管穿刺或其他开口的方法和装置。本文所述的装置和方法被配置用于在伤口的外表面上绕过穿刺部位周围的组织的一部分进行伤口闭合。例如，组织外翻装置可以被配置为用于画出围绕静脉或动脉穿刺的容器的一部分，并且至少部分地向外定向容器的内表面，使得闭合元件可以围绕在船的外表面。在一些实施方案中，所述装置是生物可吸收的。

65. 发明申请

US20120035630A1 CLOSURE DEVICE WITH LONG TINES 有权
标题翻译：带长条的闭合装置
公开(公告)号：US20120035630A1
公开(公告)日：2012-02-09
申请号：US12850242
申请日：2010-08-04
申请人： Wouter E. Roorda
发明人： Wouter E. Roorda
IPC分类号： A61B17/03
CPC分类号： A61B17/064 , A61B2017/00668 , A61B2017/0641
摘要： A device for engaging tissue may include a generally annular-shaped body defining a plane and disposed about a central axis extending substantially normal to the plane. The body may be movable from a substantially planar configuration lying generally in the plane towards a transverse configuration extending out of the plane. The body may include a plurality of looped elements including alternating inner and outer curved regions. The inner curved regions may define an inner periphery of the body and the outer curved regions may define an outer periphery of the body in the planar configuration. A plurality of tines may extend from the outer curved regions. The tines may be oriented generally towards the central axis in the planar configuration and generally parallel to the central axis in the transverse configuration. The tines may extend beyond the central axis without passing through the central axis so as to collectively form a central lumen about the central axis in the planar configuration.
摘要翻译：用于接合组织的装置可以包括限定平面的大致环形的主体，并围绕基本上垂直于该平面延伸的中心轴设置。主体可以从通常在平面中的基本上平面的构造移动到横向延伸出平面的横向构型。主体可以包括多个环形元件，包括交替的内部和外部弯曲区域。内弯曲区域可以限定主体的内周边，并且外弯曲区域可以在平面构型中限定主体的外周。多个齿可以从外部弯曲区域延伸。尖齿可以在平面构造中大致朝向中心轴定向，并且在横向构型中大致平行于中心轴线。齿可以延伸超过中心轴线而不穿过中心轴线，以便在平面构型中围绕中心轴线共同形成中心腔。

66. 发明授权

US08007858B2 System and method for coating implantable devices 有权
标题翻译：可植入装置涂层的系统和方法
公开(公告)号：US08007858B2
公开(公告)日：2011-08-30
申请号：US12363538
申请日：2009-01-30
申请人： Stephen D. Pacetti , Wouter E. Roorda , Ni Ding
发明人： Stephen D. Pacetti , Wouter E. Roorda , Ni Ding
IPC分类号： A61L33/00
CPC分类号： B05D3/0466 , A61L31/16 , A61L2300/416 , A61L2300/606 , A61L2420/02 , B05D3/0473 , B05D3/048 , Y10T428/1393 , Y10T428/31507 , Y10T428/31551 , Y10T428/31725 , Y10T428/31786 , Y10T428/31855
摘要： A method and system of coating an implantable device, such as a stent, are provided.
摘要翻译：提供涂覆可植入装置（例如支架）的方法和系统。

67. 发明授权

US07955615B2 Polycationic peptide coatings and methods of coating implantable medical devices 有权
公开(公告)号：US07955615B2
公开(公告)日：2011-06-07
申请号：US11212376
申请日：2005-08-26
申请人： Stephen D. Pacetti , Eugene T. Michal , Syed F. A. Hossainy , Ni Ding , Wouter E. Roorda
发明人： Stephen D. Pacetti , Eugene T. Michal , Syed F. A. Hossainy , Ni Ding , Wouter E. Roorda
IPC分类号： A61F2/04
CPC分类号： A61K31/727 , A61K31/728 , A61K31/737 , A61L31/10 , C08L89/00
摘要： Coatings for medical devices which include polycationic peptides such as L-arginine and methods for fabricating the coatings are disclosed.

68. 发明授权

US07875286B2 Polycationic peptide coatings and methods of coating implantable medical devices 有权
标题翻译：聚阳离子肽涂层和涂覆可植入医疗器械的方法
公开(公告)号：US07875286B2
公开(公告)日：2011-01-25
申请号：US11213290
申请日：2005-08-26
申请人： Stephen D. Pacetti , Eugene T. Michal , Syed F. A. Hossainy , Ni Ding , Wouter E. Roorda
发明人： Stephen D. Pacetti , Eugene T. Michal , Syed F. A. Hossainy , Ni Ding , Wouter E. Roorda
IPC分类号： A61F2/02
CPC分类号： A61K31/727 , A61K31/728 , A61K31/737 , A61L31/10 , C08L89/00
摘要： Coatings for medical devices which include polycationic peptides such as L-arginine and methods for fabricating the coatings are disclosed.
摘要翻译：公开了包括聚阳离子肽如L-精氨酸的医疗器械用涂层和制造涂层的方法。

69. 发明授权

US07803406B2 Polycationic peptide coatings and methods of coating implantable medical devices 有权
标题翻译：聚阳离子肽涂层和涂覆可植入医疗器械的方法
公开(公告)号：US07803406B2
公开(公告)日：2010-09-28
申请号：US11213288
申请日：2005-08-26
申请人： Stephen D. Pacetti , Eugene T. Michal , Syed F. A. Hossainy , Ni Ding , Wouter E. Roorda
发明人： Stephen D. Pacetti , Eugene T. Michal , Syed F. A. Hossainy , Ni Ding , Wouter E. Roorda
IPC分类号： A61K9/50
CPC分类号： A61K31/727 , A61K31/728 , A61K31/737 , A61L31/10 , C08L89/00
摘要： Methods of forming coatings comprising a polycationic peptide for medical devices are disclosed. Also disclosed is a coating comprising a polycationic peptide.
摘要翻译：公开了形成包含用于医疗装置的聚阳离子肽的涂层的方法。还公开了包含聚阳离子肽的涂层。

70. 发明申请

US20100185234A1 CLOSURE DEVICES, SYSTEMS, AND METHODS 审中-公开
标题翻译：封闭装置，系统和方法
公开(公告)号：US20100185234A1
公开(公告)日：2010-07-22
申请号：US12688065
申请日：2010-01-15
申请人： Aaron M. Fortson , Wouter E. Roorda
发明人： Aaron M. Fortson , Wouter E. Roorda
IPC分类号： A61B17/03
CPC分类号： A61B17/0057 , A61B2017/00646 , A61B2017/00654
摘要： The present disclosure includes vessel closure devices, systems, and methods. A closure device configured to close an opening in a body lumen may include an elongate member having a distal end and a proximal end. An anchor member may be disposed on the elongate member proximate the distal end of the elongate member. A cap member may also be disposed on the elongate member a distance from the distal end of the elongate member. The anchor member and the cap member cooperate to close the opening in the body lumen.
摘要翻译：本公开包括容器封闭装置，系统和方法。构造成关闭体腔内的开口的闭合装置可以包括具有远端和近端的细长构件。锚定构件可以设置在细长构件附近的细长构件的远端。盖构件也可以从细长构件的远端延伸一定距离的细长构件。锚固构件和帽构件协作以关闭体腔中的开口。

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