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    • 64. 发明申请
    • Drug delivery device using microprojections
    • 药物输送装置使用微喷射
    • US20050273049A1
    • 2005-12-08
    • US10863044
    • 2004-06-08
    • Peter KrulevitchMariam Maghribi
    • Peter KrulevitchMariam Maghribi
    • A61F2/958A61M25/00A61M29/02A61M29/00
    • A61M25/10A61M2025/0057A61M2025/1013A61M2025/105A61M2025/1086
    • A device for delivering a therapeutic agent into tissue includes: an elongated body; and a first balloon in the body expandable from a collapsed position to an expanded position; and a second balloon in the body expandable from a collapsed position to an expanded position. The second balloon has a plurality of apertures therein. A therapeutic agent is located in the second balloon. A plurality of microprojections are located on a surface of the second balloon for penetrating tissue. Upon expansion of the first balloon from the collapsed position to the expanded position, the second balloon is expanded from the collapsed position to the expanded position for deploying the plurality of microprojections into tissue and for dispensing the therapeutic agent from the second balloon into the tissue through the plurality of apertures.
    • 用于将治疗剂递送到组织中的装置包括:细长体; 并且所述主体中的第一气球从折叠位置可展开到展开位置; 以及主体中的第二球囊,其从折叠位置可扩展到展开位置。 第二气球在其中具有多个孔。 治疗剂位于第二气囊中。 多个微突出物位于第二球囊的用于穿透组织的表面上。 当第一气囊从折叠位置膨胀到扩张位置时,第二气囊从折叠位置膨胀到扩张位置,用于将多个微突出物展开到组织中,并且用于将治疗剂从第二气囊分配到组织中 多个孔。