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61. 发明授权

US5799120A Waveguide type wavelength multiplexing/demultiplexing module 失效
标题翻译：波导型波长复用/解复用模块
公开(公告)号：US5799120A
公开(公告)日：1998-08-25
申请号：US759748
申请日：1996-12-03
申请人： Kazuhiko Kurata , Naoki Kimura
发明人： Kazuhiko Kurata , Naoki Kimura
IPC分类号： G02B6/30 , G02B6/12 , G02B6/122 , G02B6/34 , G02B6/42 , G02B6/26
CPC分类号： G02B6/2938 , G02B6/12007 , G02B6/4246 , G02B2006/12109 , G02B2006/12147 , G02B2006/12164 , G02B6/29332 , G02B6/29368
摘要： In a waveguide type wavelength multiplexing/demultiplexing (WDM) module, a wavelength multiplexing/demultiplexing function can be realized with a half length of the conventional directional coupling device. The waveguide type WDM module is comprised of: a common waveguide for conducting first signal light having a first wavelength and second signal light having a second wavelength; common light input/output means coupled to the common waveguide; a substrate containing a WDM unit for multiplexing/demultiplexing the first signal light and the second signal light; a first waveguide for conducting the first signal light; first light input/output means optically coupled to the first waveguide; and second light input/output means for inputting/outputting the second signal light. The WDM unit includes a directional coupling type WDM device constituted by two sets of waveguides connected to the first waveguide and the common waveguide respectively. The directional coupling type WDM device is comprised of: a first edge surface perpendicular to a waveguide for constituting a directional coupling unit at a position equal to a half of a complete coupling length with respect to the first signal light in the directional coupling unit; and wavelength selecting means arranged at the first edge surface, for reflecting the first signal light and for passing there-through the second signal light; and the second light input/output means is comprised of coupling means for optically being coupled to the second signal light at the first edge surface.
摘要翻译：在波导型波分复用/解复用（WDM）模块中，可以用常规定向耦合器件的一半长度实现波长复用/解复用功能。波导型WDM模块包括：用于传导具有第一波长的第一信号光和第二波长的第二信号光的公共波导; 共同的光输入/输出装置耦合到公共波导; 包含用于对第一信号光和第二信号光进行多路复用/解复用的WDM单元的基板; 用于传导第一信号光的第一波导; 光耦合到第一波导的第一光输入/输出装置; 以及用于输入/输出第二信号光的第二光输入/输出装置。 WDM单元包括分别连接到第一波导和公共波导的两组波导构成的定向耦合型WDM器件。定向耦合型WDM器件包括：垂直于波导的第一边缘表面，用于在相对于定向耦合单元中的第一信号光的等于完整耦合长度的一半的位置处构成定向耦合单元; 以及布置在所述第一边缘表面处的波长选择装置，用于反射所述第一信号光并通过所述第二信号光; 并且第二光输入/输出装置包括用于在第一边缘表面处光耦合到第二信号光的耦合装置。

62. 发明授权

US08846870B2 Anti-HS6ST2 antibodies and uses thereof 有权
标题翻译：抗HS6ST2抗体及其用途
公开(公告)号：US08846870B2
公开(公告)日：2014-09-30
申请号：US12998988
申请日：2009-12-22
申请人： Shigeto Kawai , Naoki Kimura
发明人： Shigeto Kawai , Naoki Kimura
IPC分类号： C07K16/00 , G01N33/574 , C07K16/30 , C07K16/40 , C07K16/28
CPC分类号： C07K16/30 , C07K16/28 , C07K16/40 , C07K2317/73 , C07K2317/732 , G01N33/57423 , G01N33/57438 , G01N33/57449
摘要： The present invention provides antibodies that bind to HS6ST2 proteins, pharmaceutical compositions comprising the antibodies as active ingredients, methods for diagnosing cancer using the antibodies, HS6ST2 proteins conjugated to cytotoxic agents and pharmaceutical compositions comprising the HS6ST2 proteins as active ingredients.
摘要翻译：本发明提供结合HS6ST2蛋白的抗体，包含抗体作为活性成分的药物组合物，使用抗体诊断癌症的方法，与细胞毒性剂缀合的HS6ST2蛋白和包含HS6ST2蛋白作为活性成分的药物组合物。

63. 发明授权

US08569454B2 YS68 polypeptide involved in primitive hematopoiesis 失效
标题翻译：涉及原始造血的YS68多肽
公开(公告)号：US08569454B2
公开(公告)日：2013-10-29
申请号：US12837241
申请日：2010-07-15
申请人： Tetsuya Taga , Naoki Kimura
发明人： Tetsuya Taga , Naoki Kimura
IPC分类号： C07K14/475
CPC分类号： C07K14/47 , A61K38/00
摘要： A novel gene, dubbed “YS68”, involved in primitive hematopoiesis was successfully isolated from cDNA derived from mouse yolk sacs. In addition, a human gene corresponding to this gene was successfully isolated. Expression characteristics of these genes suggested their involvement in primitive hematopoiesis. The proteins of this invention and genes encoding the proteins may be utilized as tools for drug development against diseases, such as hematological disorders.
摘要翻译：从源自小鼠卵黄囊的cDNA中成功分离了一种称为“YS68”的新基因，涉及原始造血。此外，成功分离了与该基因相对应的人类基因。这些基因的表达特征表明它们参与原始造血。本发明的蛋白质和编码蛋白质的基因可以用作针对疾病如血液学疾病的药物开发的工具。

64. 发明授权

US08158385B2 Cell death-inducing agent 失效
标题翻译：细胞死亡诱导剂
公开(公告)号：US08158385B2
公开(公告)日：2012-04-17
申请号：US10530696
申请日：2003-10-10
申请人： Shuji Ozaki , Masahiro Abe , Masayuki Tsuchiya , Naoki Kimura , Shigeto Kawai
发明人： Shuji Ozaki , Masahiro Abe , Masayuki Tsuchiya , Naoki Kimura , Shigeto Kawai
IPC分类号： C12P21/04 , C12P21/08
CPC分类号： C07K16/2833 , A61K2039/505 , C07K14/70539 , C07K2317/34 , C07K2317/565 , C07K2317/626 , C07K2317/73
摘要： To identify antigens of the 2D7 antibody, the present inventors cloned the 2D7 antigen. The results suggested that the 2D7 antigen is an HLA class I molecule. Based on this finding, the present inventors examined whether the 2D7 antibody has cell death-inducing activity. Nuclei fragmentation was observed when the 2D7 antibody was cross-linked with another antibody, indicating that cell-death was induced. Further, diabodies of the 2D7 antibody were found to have very strong cell death-inducing activities, even without the addition of another antibody. These results indicate that minibodies of an HLA-recognizing antibody can be used as cell death-inducing agents.
摘要翻译：为了鉴定2D7抗体的抗原，本发明人克隆了2D7抗原。结果表明，2D7抗原是HLA I类分子。基于该发现，本发明人检查了2D7抗体是否具有细胞死亡诱导活性。当2D7抗体与另一种抗体交联时，观察到细胞核碎裂，表明诱导细胞死亡。此外，发现2D7抗体的双抗体具有非常强的细胞死亡诱导活性，即使没有添加另一种抗体。这些结果表明HLA识别抗体的小体抗体可以用作细胞死亡诱导剂。

65. 发明授权

US08158284B2 Lithium ion secondary battery 有权
标题翻译：锂离子二次电池
公开(公告)号：US08158284B2
公开(公告)日：2012-04-17
申请号：US12354039
申请日：2009-01-15
申请人： Naoki Kimura
发明人： Naoki Kimura
IPC分类号： H01M4/13 , H01M4/58 , C01B31/00 , C01B31/02 , C01B31/04
CPC分类号： H01M10/0525 , H01M4/366 , H01M4/587 , Y02E60/122 , Y02T10/7011
摘要： A lithium ion secondary battery is capable of improving the energy density and power density and excellent in high rate cycle characteristics applicable to hybrid cars, etc. The lithium ion secondary battery including a positive electrode of a lithium transition metal complex oxide, a negative electrode for absorbing/releasing lithium, and a non-aqueous electrolyte containing a lithium salt, in which the negative electrode has a negative electrode active material using a non-graphitizing carbon (spacing d(002) of 0.360 nm or more by XRD) and a graphitizing carbon (spacing d(002) of 0.339 nm or more and less than 0.360 nm by XRD) surface-modified at a thickness in a range from 10 nm to 100 nm in admixture, comprising the non-graphitizing carbon and the graphitizing carbon at a ratio in the range of 90 to 50 wt % :10 to 50 wt % and, further, graphitizing carbon having a grain size larger than that of the non-graphitizing carbon is used.
摘要翻译：锂离子二次电池能够提高能量密度和功率密度以及适用于混合动力汽车等的高速循环特性优异。锂离子二次电池包括锂过渡金属复合氧化物的正极，负极吸收/释放锂，以及含有锂盐的非水电解质，其中负极具有使用非石墨化碳的负极活性物质（通过XRD的间隔d（002）为0.360nm以上）和石墨化碳（通过XRD测定的0.339nm以上，0.339nm以上且小于0.360nm的间隔d（002））在10nm〜100nm的范围内进行表面改性，包含非石墨化碳和石墨化碳比率在90〜50重量％的范围内：10〜50重量％，进一步使用比非石墨化碳的粒径大的石墨化碳。

66. 发明授权

US08053970B2 Light emitting device and illumination device 有权
标题翻译：发光装置及照明装置
公开(公告)号：US08053970B2
公开(公告)日：2011-11-08
申请号：US12369351
申请日：2009-02-11
申请人： Naoki Kimura , Ryuji Suzuki , Ken Sakuma , Naoto Hirosaki
发明人： Naoki Kimura , Ryuji Suzuki , Ken Sakuma , Naoto Hirosaki
IPC分类号： H05B33/14
CPC分类号： C09K11/7734 , C09K11/7774 , H01L33/502 , H01L2224/45144 , H01L2224/48091 , Y02B20/181 , H01L2924/00014 , H01L2924/00
摘要： An LED with a semiconductor light emitting element that emits a blue or a blue-violet light, and a fluorescent material that absorbs some or all of the light emitted from the element and emits a fluorescent light of a wavelength different from the absorbed light. The fluorescent material is a mixed fluorescent material obtained by mixing a first fluorescent material that emits a blue-green or a green light, a second fluorescent material that has a peak emission wavelength longer than that of the first fluorescent material and emits a green or a yellow-green light, a third fluorescent material that has a 1 peak emission wavelength longer than that of the second fluorescent material and emits a yellow-green, a yellow or a yellow-red light, and a fourth fluorescent material that has a peak emission wavelength longer than that of the third fluorescent material and emits a yellow-red or a red light.
摘要翻译：具有发射蓝色或蓝紫色光的半导体发光元件的LED以及吸收从元件发射的一些或全部光并发射与吸收光不同的波长的荧光的荧光材料。荧光材料是通过混合发射蓝绿色或绿色光的第一荧光材料获得的混合荧光材料，具有比第一荧光材料的峰值发射波长长的发光波长的第二荧光材料，并发出绿色或黄绿色光，具有比第二荧光材料长的1个峰值发射波长并发射黄绿色，黄色或黄色 - 红色光的第三荧光材料，以及具有峰值发光的第四荧光材料波长比第三荧光材料长，并发出黄红色或红色光。

67. 发明申请

US20110262929A1 ANTI-HS6ST2 ANTIBODIES AND USES THEREOF 有权
标题翻译：抗HS6ST2抗体及其用途
公开(公告)号：US20110262929A1
公开(公告)日：2011-10-27
申请号：US12998988
申请日：2009-12-22
申请人： Shigeto Kawai , Naoki Kimura
发明人： Shigeto Kawai , Naoki Kimura
IPC分类号： C12Q1/68 , A61P35/00 , C12N9/96 , C07K16/40 , C12Q1/48
CPC分类号： C07K16/30 , C07K16/28 , C07K16/40 , C07K2317/73 , C07K2317/732 , G01N33/57423 , G01N33/57438 , G01N33/57449
摘要： The present invention provides antibodies that bind to HS6ST2 proteins, pharmaceutical compositions comprising the antibodies as active ingredients, methods for diagnosing cancer using the antibodies, HS6ST2 proteins conjugated to cytotoxic agents and pharmaceutical compositions comprising the HS6ST2 proteins as active ingredients.
摘要翻译：本发明提供结合HS6ST2蛋白的抗体，包含抗体作为活性成分的药物组合物，使用抗体诊断癌症的方法，与细胞毒性剂缀合的HS6ST2蛋白和包含HS6ST2蛋白作为活性成分的药物组合物。

68. 发明申请

US20110235498A1 OPTICAL DISK DEVICE AND POWER SUPPLY METHOD 失效
标题翻译：光盘设备和电源方法
公开(公告)号：US20110235498A1
公开(公告)日：2011-09-29
申请号：US13158253
申请日：2011-06-10
申请人： Manabu Murakami , Shigeru Fukinuki , Naoki Kimura
发明人： Manabu Murakami , Shigeru Fukinuki , Naoki Kimura
IPC分类号： G11B7/125
CPC分类号： G11B7/126 , G11B7/1275 , G11B2007/0006
摘要： According to one embodiment, an optical disk device includes types of semiconductor laser diodes configured to emit laser light of different wavelengths, an output control circuit configured to control light output of each semiconductor laser diode, and a composite power source configured to generate voltages required for driving the types of semiconductor laser diodes and operating the output control circuit from a single power source voltage and to selectively output the generated voltages. The composite power source includes an input port to input an external control signal at a time of voltage selection and is configured to change the output voltage stepwise in response to the control signal.
摘要翻译：根据一个实施例，光盘装置包括配置为发射不同波长的激光的半导体激光二极管的类型，被配置为控制每个半导体激光二极管的光输出的输出控制电路和被配置为产生驱动类型的半导体激光二极管，并从单个电源电压操作输出控制电路并选择性地输出所产生的电压。复合电源包括在电压选择时输入外部控制信号的输入端口，并且被配置为响应于控制信号逐步改变输出电压。

70. 发明授权

US07668408B2 Support apparatus for optical characteristic measurement, and program product used for same 有权
标题翻译：用于光学特性测量的支持装置，以及用于其的程序产品
公开(公告)号：US07668408B2
公开(公告)日：2010-02-23
申请号：US11398792
申请日：2006-04-06
申请人： Naoki Kimura , Toru Kobayashi , Norio Ishikawa
发明人： Naoki Kimura , Toru Kobayashi , Norio Ishikawa
IPC分类号： G06K7/10 , G06K9/20
CPC分类号： G01J3/50 , G01J3/02 , G01J3/0264 , G01J3/027 , G01J3/0289 , G01N21/25
摘要： A support apparatus for optical characteristic measurement includes a measurement data inputter configured to input measurement data obtained by an optical characteristic measuring instrument, an image inputter configured to input an image of a measurement object, a measurement table in which the measurement data and the image of the measurement object corresponding to the measurement data are recorded, and a measurement data manager configured to record the measurement data inputted by the measurement data inputter in the measurement table so as to be associated with the image of the measurement object every time an optical characteristic of the measurement object is measured.
摘要翻译：用于光学特性测量的支持装置包括测量数据输入器，被配置为输入由光学特性测量仪器获得的测量数据，被配置为输入测量对象的图像的图像输入器，测量数据和测量数据的图像记录与测量数据相对应的测量对象，并且测量数据管理器被配置为将测量数据输入器输入的测量数据记录在测量表中，以便每当测量对象的光学特性测量对象。

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