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    • 62. 发明申请
    • Cycloaliphatic polyepoxy compounds and prepartation thereof
    • 环脂族聚环氧化合物及其制备
    • US20080004425A1
    • 2008-01-03
    • US11819615
    • 2007-06-28
    • Takashi KuboTatsuya NakanoTakahiro Iwahama
    • Takashi KuboTatsuya NakanoTakahiro Iwahama
    • C08G59/00C08G65/00C08L63/00
    • C08G59/24C07D303/16C07D303/40
    • Is disclosed a cycloaliphatic polyepoxy compound represented by following Formula (1): wherein Y represents a linkage group or a single bond; and HAs each represent hydrogen atom at the junction between cyclohexane ring and oxirane ring, and the cyclohexane rings may each further have one or more substituents in addition to the groups shown in the formula. The cycloaliphatic polyepoxy compound contains stereoisomers in such proportions as to have a ratio A/B of 1.8 or more, wherein “A” and “B” are integrated intensities of signals of protons at the junction between cyclohexane ring and oxirane ring as determined by 1H-NMR spectroscopy of the compound, in which “A” represents the integrated intensity of a signal observed at a lower magnetic field, and “B” represents the integrated intensity of a signal observed at a higher magnetic field.
    • 公开了由下式(1)表示的脂环族聚环氧化合物:其中Y表示连接基团或单键; 和H A S各自表示环己烷环和环氧乙烷环之间的连接处的氢原子,除了式中所示的基团外,环己烷环还可以具有一个或多个取代基。 脂环族聚环氧化合物含有比例为A / B为1.8以上的立体异构体,其中“A”和“B”是在环己烷环与环氧乙烷环之间的连接处的质子信号的积分强度, 化合物的1 H-NMR光谱,其中“A”表示在较低磁场下观察到的信号的积分强度,“B”表示在较高磁场下观察到的信号的积分强度 领域。
    • 66. 发明授权
    • Malic acid and oxalacetic acid derivatives
    • 苹果酸和草乙酸衍生物
    • US06489504B2
    • 2002-12-03
    • US09801648
    • 2001-03-09
    • Yasutaka IshiiTatsuya Nakano
    • Yasutaka IshiiTatsuya Nakano
    • C07C6521
    • C07C69/716C07C69/675C07C2603/00C07C2603/74
    • A malic acid or oxalacetic acid derivative is represented by the following formula (1): wherein ring Z is an alicyclic carbon ring; each of Ra and Rb is independently a hydrogen atom, a metal atom, or an organic group; and Y is a hydroxyl group or an oxygen atom, where ring Z is a bridged carbon ring or a monocyclic carbon ring having eight or more members when Y is an oxygen atom. The alicyclic carbon ring includes, for example, cyclooctane ring and adamantane ring. This compound is a novel malic acid derivative having an alicyclic group bonded to a carbon atom at the 3-position, or a novel oxalacetic acid derivative having a specific alicyclic group bonded to a carbon atom at the 3-position.
    • 苹果酸或草乙酸衍生物由下式(1)表示:其中环Z是脂环碳环; Ra和Rb各自独立地为氢原子,金属原子或有机基团; Y为羟基或氧原子,当Y为氧原子时,其中环Z为桥碳环或具有8个以上成员的单环碳环。 脂环碳环包括例如环辛烷环和金刚烷环。 该化合物是具有与3-位上的碳原子键合的脂环基的新型苹果酸衍生物,或具有与3-位上的碳原子键合的特定脂环基的新型草乙酸衍生物。
    • 68. 发明授权
    • Process for the preparation of hydroxyadamantanone derivatives
    • 羟基金刚烷酮衍生物的制备方法
    • US06229050B1
    • 2001-05-08
    • US09647460
    • 2000-09-29
    • Tatsuya Nakano
    • Tatsuya Nakano
    • C07C4561
    • C07C49/513Y02P20/55
    • The invented process produces a corresponding 5-hydroxy-2-adamantanone derivative by allowing a 2-adamantanone derivative of the following formula (1): wherein each of Ra, Rb, and Rc is, identical to or different from one another, a hydrogen atom, a halogen atom, an alkyl group, a hydroxyl group which may be protected by a protective group, a hydroxymethyl group which may be protected by a protective group, an amino group which may be protected by a protective group, a carboxyl group which may be protected by a protective group, or a nitro group, and of carbon atoms constituting an adamantane skeleton, the other carbon atoms than carbon atoms at bridgehead positions and at a bonding position of an oxo group may have a substituent, to react with oxygen in the presence of N-hydroxyphthalimide or another imide compound, a vanadium compound, and a manganese compound.
    • 本发明方法通过使下式(1)的2-金刚烷酮衍生物生成相应的5-羟基-2-金刚烷酮衍生物:其中Ra,Rb和Rc各自彼此相同或不同,为氢 原子,卤素原子,烷基,可被保护基保护的羟基,可被保护基保护的羟甲基,可被保护基保护的氨基,羧基, 可以被保护基,硝基和构成金刚烷骨架的碳原子保护,在桥头位置的碳原子和氧代基的键合位置处的其它碳原子可以具有取代基,与氧反应 在N-羟基邻苯二甲酰亚胺或其它酰亚胺化合物,钒化合物和锰化合物的存在下。