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61. 发明申请

US20080280938A1 Screening Method 失效
标题翻译：筛选方法
公开(公告)号：US20080280938A1
公开(公告)日：2008-11-13
申请号：US11885781
申请日：2006-03-07
申请人： Masaaki Mori , Kimiko Kanehashi
发明人： Masaaki Mori , Kimiko Kanehashi
IPC分类号： A61K31/473 , G01N33/566 , G01N33/53
CPC分类号： A61K31/473 , G01N2500/02
摘要： The present invention provides a medicament for preventing/treating cancer, comprising a tacrine compound, or a compound promoting the binding between the tacrine compound and a protein comprising the same or substantially the same amino acid sequence as the amino acid sequence represented by SEQ ID NO: 1.
摘要翻译：本发明提供了用于预防/治疗癌症的药物，其包含他克林化合物或促进他克林化合物与包含与SEQ ID NO所示氨基酸序列相同或基本相同的氨基酸序列的蛋白质之间的结合的化合物：1。

62. 发明申请

US20070117160A1 Novel method of screening 有权
标题翻译：新型筛选方法
公开(公告)号：US20070117160A1
公开(公告)日：2007-05-24
申请号：US11587285
申请日：2005-04-22
申请人： Ryo Fujii , Kazunori Nishi , Yasuhiro Tanaka , Masaaki Mori
发明人： Ryo Fujii , Kazunori Nishi , Yasuhiro Tanaka , Masaaki Mori
IPC分类号： G01N33/567 , G01N33/53
CPC分类号： G01N33/566 , G01N2333/726 , G01N2500/00 , Y10S435/975
摘要： The present invention relates to screening of an agonist/antagonist, etc. Specifically, the present invention provides a method of screening an agonist or antagonist of a G protein-coupled receptor protein comprising the same or substantially the same amino acid sequence as the amino acid sequence represented by SEQ ID NO: 1, or a salt thereof, which comprises using the receptor protein or a salt thereof and a cholesterol metabolism-related substance, and so on.
摘要翻译：本发明涉及激动剂/拮抗剂等的筛选。具体而言，本发明提供筛选G蛋白偶联受体蛋白的激动剂或拮抗剂的方法，其包含与氨基酸相同或基本上相同的氨基酸序列由SEQ ID NO：1表示的序列或其盐，其包括使用受体蛋白质或其盐和胆固醇代谢相关物质等。

63. 发明申请

US20070042947A1 Agents for preventing and/or treating uppper digestive tract disorders 审中-公开
标题翻译：用于预防和/或治疗上消化道疾病的药剂
公开(公告)号：US20070042947A1
公开(公告)日：2007-02-22
申请号：US10548817
申请日：2004-03-11
申请人： Hirokazu Matsumoto , Koh Takagi , Masaaki Mori
发明人： Hirokazu Matsumoto , Koh Takagi , Masaaki Mori
IPC分类号： A61K38/17
CPC分类号： A61K38/177 , A61K38/1709 , C12N2310/11 , G01N2800/06
摘要： A compound or its salts that inhibit the activity of the polypeptide or receptor of the present invention and the antibody of the present invention as well as the antisense DNA of the present invention are useful as, e.g., gastric acid secretion inhibitors, mucosa protectants, mineral absorption promoters, etc., which are less toxic and safe, and can be used as, e.g., agents for preventing/treating upper digestive tract disorders, antibacterial agents to Helicobacter pylori, etc. A compound or its salts that promote the activity of the polypeptide or receptor of the present invention, the polypeptide or receptor of the present invention and the DNA of the present invention can be used as, e.g., gastric acid secretion promoters and can be used as, e.g., agents for preventing/treating dyspepsia, bone metabolism disorders, anemia, etc. A compound or its salts that promote the activity of the polypeptide or receptor of the present invention, the polypeptide of the present invention, etc. can also be used as test agents for gastric secretory function. Furthermore, the polypeptide or receptor of the present invention and the DNA of the present invention are also useful for screening the agents for the prevention/treatment described above.
摘要翻译：抑制本发明的多肽或受体和本发明的抗体以及本发明的反义DNA的活性的化合物或其盐可用于例如胃酸分泌抑制剂，粘膜保护剂，矿物质吸收促进剂等，其毒性和安全性较低，并且可以用作例如用于预防/治疗上消化道疾病的药剂，对幽门螺杆菌等的抗菌剂。促进幽门螺杆菌活性的化合物或其盐本发明的多肽或受体，本发明的多肽或受体和本发明的DNA可以用作例如胃酸分泌促进剂，并且可以用作例如用于预防/治疗消化不良，骨骼的药剂代谢紊乱，贫血等。促进本发明的多肽或受体的活性，本发明的多肽等的化合物或其盐。c 也可用作胃分泌功能的试剂。此外，本发明的多肽或受体和本发明的DNA也可用于筛选用于上述预防/治疗的药剂。

64. 发明授权

US06274870B1 Method for spectrometrically measuring isotopic gas and apparatus thereof 有权
标题翻译：光谱测量同位素气体的方法及其装置
公开(公告)号：US06274870B1
公开(公告)日：2001-08-14
申请号：US09303427
申请日：1999-05-03
申请人： Yasuhiro Kubo , Katsuhiro Morisawa , Yasushi Zasu , Eiji Ikegami , Kazunori Tsutsui , Tamotsu Hamao , Masaaki Mori , Takashi Maruyama
发明人： Yasuhiro Kubo , Katsuhiro Morisawa , Yasushi Zasu , Eiji Ikegami , Kazunori Tsutsui , Tamotsu Hamao , Masaaki Mori , Takashi Maruyama
IPC分类号： G01N2135
CPC分类号： G01N21/3504 , A61B5/0059 , A61B5/0836 , A61B5/097 , A61B10/00 , A61B2010/0087 , G01N21/0332 , G01N21/11 , G01N21/274 , G01N21/314 , G01N33/0006 , G01N33/497
摘要： A correction curve (FIG. 19) is prepared by plotting 12CO2 concentrations and 13CO2/12CO2 concentration ratios which are determined on the basis of a calibration curve and 13CO2 and 12CO2 absorbances of gaseous samples having the same 13CO2/12CO2 concentration ratio but known different 12CO2 concentrations. A gaseous test sample containing 13CO2 and 12CO2 as component gases is introduced into a cell, and spectrometrically measured. A 12CO2 concentration of the gaseous test sample is determined by way of the spectrometric measurement. A concentration ratio correction value is obtained on the basis of the correction curve and the 12CO2 concentration of the gaseous test sample thus determined. A measured 13CO2/12CO2 concentration ratio is divided by the concentration ratio correction value thus obtained for correction of the 13CO2/12CO2 concentration ratio. Thus, the measurement accuracy of the concentration ratios of the component gases can be improved.
摘要翻译：通过绘制12CO2浓度和13CO2 / 12CO2浓度比，通过绘制12CO2浓度和13CO2 / 12CO2浓度比来制备校正曲线（13CO2 / 12CO2浓度比），这些浓度比是根据13CO2 / 12CO2浓度比相同但已知不同12CO2的气态样品的校正曲线和13CO2和12CO2吸光度确定的浓度将含有作为组分气体的13CO 2和12 CO 2的气态测试样品引入到电池中，并进行光谱测量。通过光谱测量法测定气态测试样品的12CO2浓度。基于如此确定的气体试样的校正曲线和12CO 2浓度获得浓度比校正值。测量的13CO 2 / 12CO 2浓度比除以由此获得的用于校正13CO 2 / 12CO 2浓度比的浓度比校正值。因此，能够提高成分气体的浓度比的测定精度。

65. 再颁专利

USRE35886E Phosphonic acid derivatives and use thereof 失效
标题翻译：膦酸衍生物及其用途
公开(公告)号：USRE35886E
公开(公告)日：1998-09-01
申请号：US680295
申请日：1996-07-12
申请人： Mitsuhiro Wakimasu , Masaaki Mori , Akira Kawada
发明人： Mitsuhiro Wakimasu , Masaaki Mori , Akira Kawada
IPC分类号： A61K38/00 , A61K38/55 , A61P9/00 , A61P9/12 , A61P13/02 , A61P15/00 , C07K1/06 , C07K1/113 , C07K5/06 , C07F9/22 , A61K33/42
CPC分类号： C07K5/06191 , A61K38/00 , Y02P20/55
摘要： A phosphonic acid derivative compound represented by formula �I ! or a pharmaceutically acceptable salt thereof: ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3 each represent hydrocarbon groups which may be substituted, except cases in which (1) R.sub.2 is unsubstituted methyl, ( 2 ) R.sub.3 is an unsubstituted hydrocarbon group having 1 to 3 carbon atoms, and (3) R.sub.1 is benzyloxycarbonylaminomethyl, R.sub.2 is isobutyl and R.sub.3 is isobutyl or phenylmethyl, which has endothelin-converting enzyme inhibiting activity and is useful as pharmaceutical drugs such as therapeutic agents for hypertension, cardiac or cerebral circulatory diseases and renal diseases. This is a Reissue of a Patent which was the subject of a Reexamination Certificate No. B1 5,330,978, dated Jun. 18, 1996, Request No. 90/00400, Oct. 18, 1995.
摘要翻译：由式[I]表示的膦酸衍生物或其药学上可接受的盐：其中R 1，R 2和R 3各自表示可以被取代的烃基，除了（1）R 2是未取代的甲基，（2）R3为未取代的碳原子数1〜3的烷基，（3）R1为苄氧羰基氨基甲基，R2为异丁基，R3为异丁基或苯甲基，具有内皮素转化酶抑制活性，可用作药物作为高血压，心脏或脑循环系统疾病和肾脏疾病的治疗剂。 + PR这是1996年10月18日，1996年10月18日申请号90/00400的1996年6月18日的复审证书B1 5,330,978的主题的重新发行。

66. 发明授权

US4748455A System for driving a thermal print head 失效
标题翻译：用于驱动热打印头的系统
公开(公告)号：US4748455A
公开(公告)日：1988-05-31
申请号：US858534
申请日：1986-04-28
申请人： Masaaki Mori
发明人： Masaaki Mori
IPC分类号： B41J2/36 , H04N1/23 , G01D15/10
CPC分类号： B41J2/36
摘要： A system for driving a thermal print head including a plurality of heat-producing elements which are activated selectively in accordance with digital image data obtained from an analog image signal is provided. In one aspect, the driving system is so structured to insert additional data between any two adjacent image data whenever the space between the two exceeds a predetermined level thereby allowing to maintain the dot density at constant when printed. In another aspect, the driving system controls the time period of activation of each of the heat-producing elements in accordance with preheat control data obtained by carrying out AND processing between each of the digital image data of one print line and the corresponding each of the digital image data of the next following print line. In a further aspect, the present driving system has a structure such that a reference point in a print line may be set at a desired location along the print line.
摘要翻译：提供一种用于驱动热打印头的系统，其包括根据从模拟图像信号获得的数字图像数据选择性地激活的多个发热元件。在一个方面，驱动系统如此构造以便每当两者之间的空间超过预定水平时，在任何两个相邻图像数据之间插入附加数据，从而允许在打印时将点密度保持恒定。在另一方面，驱动系统根据通过在一个打印行的每个数字图像数据和每个打印行的每个之间执行AND处理而获得的预热控制数据来控制每个发热元件的激活时间下一个打印行的数字图像数据。在另一方面，本驱动系统具有这样的结构，使得打印线中的参考点可以设置在沿着打印线的期望位置。

67. 发明授权

US4684959A Thermal recording system using unregulated power supply 失效
标题翻译：热记录系统采用不稳定电源
公开(公告)号：US4684959A
公开(公告)日：1987-08-04
申请号：US745908
申请日：1985-06-18
申请人： Masaaki Mori , Chiharu Okada
发明人： Masaaki Mori , Chiharu Okada
IPC分类号： B41J2/37 , B41J2/355 , G01D15/10
CPC分类号： B41J2/355
摘要： A thermal recording system includes a thermal print head provided with a plurality of electrical resistors arranged in the form of a single row and selectively activated when an activation pulse is supplied, a brute supply for supplying a power supply voltage to the resistors and a pulse generator for controlling the duration of the activation pulse in accordance with the level of the power supply voltage actually applied to the resistors. The pulse generator controls the pulse width of the activation pulse so as to maintain substantially constant the activation energy defined as a product of (power supply voltage actually applied).sup.2 and (pulse width of activation pulse).
摘要翻译：热敏记录系统包括热敏打印头，其设置有以单列形式布置的多个电阻器，并且当提供激活脉冲时被选择性地激活，用于向电阻器供应电源电压的强电源和脉冲发生器用于根据实际施加到电阻器的电源电压的电平来控制激活脉冲的持续时间。脉冲发生器控制激活脉冲的脉冲宽度，以便将作为（实际施加电源电压）2和（激活脉冲的脉冲宽度）的乘积定义的激活能保持基本恒定。

68. 发明授权

US4605813A Amorphous silicon solar battery 失效
标题翻译：非晶硅太阳能电池
公开(公告)号：US4605813A
公开(公告)日：1986-08-12
申请号：US754201
申请日：1985-07-11
申请人： Yukihisa Takeuchi , Masaaki Mori , Kenji Maekawa , Toshiaki Nishizawa
发明人： Yukihisa Takeuchi , Masaaki Mori , Kenji Maekawa , Toshiaki Nishizawa
IPC分类号： H01L31/04 , H01L27/142 , H01L31/0224 , H01L31/0392 , H01L27/14 , H01L31/06
CPC分类号： H01L31/022425 , H01L31/03921 , H01L31/046 , H01L31/0465 , Y02E10/50
摘要： A flexible amorphous silicon solar battery comprising a metal foil as the substrate thereof, an insulating layer integrally formed on the metal foil, and at least one amorphous silicon photoelectric conversion portion formed on the insulating layer. The amorphous silicon photoelectric conversion portion thereof comprises an a-Si thin film having a potential barrier therein, an upper electrode and a lower electrode. The a-Si thin film is sandwiched between the upper and lower electrodes. The upper electrodes may be formed of a transparent conductive film. The transparent conductive film may be also in two layers composed of a relatively thin tin dioxide film and a relatively thick ITO film thereby to lower the resistance of transparent conductive film and to obtain a superior a-Si thin film having no impurity particles therein. A plurality of a-Si photoelectric conversion portions may be formed on the same substrate, and are connected in series with one another, to increase the output voltage thereof. The a-Si photoelectric conversion portions may be formed as forward junction and/or reverse junction types. The a-Si solar battery of this invention is flexible because of use of a metal foil with thickness of 10 to 250 .mu.m such as stainless steel, aluminum or iron as the substrate thereof, so that it can be easily attached to a product having a curved surface thereon, such as an automobile or the like. Further, there are no problems or disadvantages, such as spallings and cracks of the a-Si thin film, or deterioration of the physical properties thereof, so that the a-Si solar battery of this invention can provide excellent conversion efficiency.
摘要翻译：一种柔性非晶硅太阳能电池，其特征在于，以金属箔为基材，在所述金属箔上一体形成的绝缘层和形成在所述绝缘层上的至少一个非晶硅光电转换部。其非晶硅光电转换部分包括其中具有势垒的a-Si薄膜，上电极和下电极。 a-Si薄膜夹在上电极和下电极之间。上部电极可以由透明导电膜形成。透明导电膜也可以由相对较薄的二氧化锡膜和较厚的ITO膜构成，从而降低透明导电膜的电阻，并获得其中没有杂质颗粒的优异的a-Si薄膜。多个a-Si光电转换部可以形成在同一基板上，并且彼此串联连接以增加其输出电压。 a-Si光电转换部分可以形成为正向结和/或反向连接类型。本发明的a-Si太阳能电池由于使用厚度为10〜250μm的金属箔（例如不锈钢，铝或铁等）作为基板而具有柔性，因此可以容易地与具有其上的曲面，例如汽车等。此外，没有诸如a-Si薄膜的剥落和裂纹或其物理性能的劣化的问题或缺点，使得本发明的a-Si太阳能电池可以提供优异的转换效率。

69. 发明授权

US10662443B2 Method for producing alkane and recombinant microorganism capable of synthesizing alkane 有权
公开(公告)号：US10662443B2
公开(公告)日：2020-05-26
申请号：US14235833
申请日：2011-08-15
申请人： Masaaki Mori
发明人： Masaaki Mori
IPC分类号： C12P5/02 , C12N9/02 , C12N15/81
摘要： A method for producing alkane and a recombinant microorganism with good alkane productivity in a reaction system for synthesizing alkane by alkane synthase activity are provided. Alkane productivity is significantly improved in a system for synthesizing alkane by alkane synthase in the presence of ferredoxin. Specifically, the method for producing alkane according to the present invention comprises synthesizing alkane by alkane synthase in the presence of ferredoxin.

70. 发明授权

US08900351B2 Filter medium and method of manufacturing the same and filter unit 有权
标题翻译：过滤介质及其制造方法及过滤单元
公开(公告)号：US08900351B2
公开(公告)日：2014-12-02
申请号：US12742625
申请日：2008-11-11
申请人： Masaaki Mori , Masatoshi Suzuki
发明人： Masaaki Mori , Masatoshi Suzuki
IPC分类号： B01D53/22 , B01D39/16
CPC分类号： B01D39/1692 , B01D69/12 , B01D71/36 , B01D2239/0654
摘要： Provided is a filter medium including a porous polytetrafluoroethylene (PTFE) membrane and a gas-permeable supporting member that are integrated to ensure sufficient stiffness, having excellent gas permeability, and providing excellent bonding between respective layers included in the filter medium. The gas-permeable supporting member includes: a substrate having gas-permeability; and a fiber layer that is placed on the substrate so as to be in contact with the porous PTFE membrane. The gas-permeable supporting member has a structure in which fibers of the fiber layer enter into the substrate and are entangled with the substrate so that the fiber layer is bonded to the substrate. The fiber layer contains polyolefin-containing fibers that are bonded to the porous membrane.
摘要翻译：提供了一种过滤介质，其包括多孔聚四氟乙烯（PTFE）膜和气体可渗透的支撑构件，其一体化以确保足够的刚度，具有优异的气体渗透性，并且在包含在过滤介质中的各个层之间提供优异的粘合。透气性支撑构件包括：具有透气性的基板; 以及放置在基板上以与多孔PTFE膜接触的纤维层。透气性支撑构件具有纤维层的纤维进入基板并与基板缠结的结构，使得纤维层与基板结合。纤维层含有与多孔膜结合的含有聚烯烃的纤维。

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